Pathogenic Variants in the ABCA12 Gene Associated to Autosomal Recessive Congenital Ichthyosis: Report of an Attenuated Phenotype by Gabriela Mantilla Beltrán, Ana María Navarro Pinilla, Diego Andrés Padilla Mantilla, Alfonso Suárez Camacho, Mónica Paola Novoa Candia

“…This article reports on the cases of two female patients with symptoms of palmoplantar keratoderma since birth and a variant in the ABCA12 gene that encodes an amino acid glucosylceramide transporter known as ABCA12. …”
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Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro by Jun-Qin Li, Hui-Jie Jiang, Xiu-Yun Su, Li Feng, Na-Zhi Zhan, Shan-Shan Li, Zi-Jie Chen, Bo-Han Chang, Peng-Zhen Cheng, Liu Yang, Guo-Xian Pei

“…Further, Schwann cells regulate amino acid metabolism and lipid metabolism in preosteoblasts. …”
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Influence of Polymorphism on Glycosylation of Serum Amyloid A4 Protein by Toshiyuki Yamada, Jyunji Sato, Kazuhiko Kotani, Masafumi Tanaka

“…The results showed that the percentage of glycosylation in subjects with amino acid substitutions at positions 71 and/or 84 was significantly (P<0.05) higher than that in subjects with the wild type. …”
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MUC5B modulation of early oral biofilm glucose metabolism by Carolina Robertsson, Carolina Robertsson, Julia Davies, Gunnel Svensäter, Anders Bay Nord, Niclas Norrström, Claes Wickström

“…All annotated metabolites were intermediates in either carbohydrate metabolism, pyruvate conversion, or amino acid metabolism, which was not unexpected in biofilm glucose metabolomes from two saccharolytic species since pyruvate conversion represents a junction point between glycolysis and amino acid metabolic chains. …”
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Characterization of the complete genome sequence of the recombinant norovirus GII.P16/GII.4_Sydney_2012 revealed in Russia by E. V. Zhirakovskaia, A. Y. Tikunov, S. N. Sokolov, B. I. Kravchuk, E. I. Krasnova, N. V. Tikunova

“…A comparison of the nucleotide and the deduced amino acid sequences showed a high homology of the Russian strain with GII.P16/GII.4_Sydney_2012 strains from other parts of the world. …”
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Serum metabolic profiles in quails: Effects of age, breed, and sex by Qin He, Hanle Shang, Yizhong Huang, Lizhi Li, Zhuomin Wu, Huihui Ran, Jiguo Xu, Xinwei Xiong

“…Differences in energy metabolism and amino acid biosynthesis and metabolism were observed between males and females. …”
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Transcriptomic and metabolomic-based revelation of the effect of fresh corn extract on meat quality of Jingyuan chicken by Jinli Tian, Yanxu Wu, Wei Zhao, Guojun Zhang, Hu Zhang, Lin Xue, Lijuan Yang, Tong Zhang, Yaling Gu, Juan Zhang

“…Meat performance measurements showed that the 0.6% FCE group of Jingyuan chickens had higher intramuscular fat (IMF), pressing loss (PL), amino acid and fatty acid contents (P < 0.05). Their breasts were collected for transcriptomic and metabolomic analyses (n=8), and 210 Differentially expressed genes (DEGs) and 29 Differentially expressed genes (DEMs) were obtained. …”
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Recombinant Anti-PF4 Antibodies Derived from Patients with Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT) Facilitate Research and Laboratory Diagnosis of VITT by Luisa Müller, Venkata A. S. Dabbiru, Lucy Rutten, Rinke Bos, Roland Zahn, Stefan Handtke, Thomas Thiele, Marta Palicio, Olga Esteban, Marta Broto, Tom Paul Gordon, Andreas Greinacher, Jing Jing Wang, Linda Schönborn

“…Recombinant antibodies (rAbs) derived from VITT patient characteristic amino acid sequences of anti-PF4 IgG are an alternative to study VITT pathophysiology. …”
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Chemical Stabilisation of Collagen as a Biomimetic by R. Gordon Paul, Allen J. Bailey

“…This can be achieved by a number of different cross-linking agents that react with specific amino acid residues on the collagen molecule imparting individual biochemical, thermal and mechanical characteristics to the biomaterial. …”
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Modeling Cu(II) Binding to Peptides Using the Extensible Systematic Force Field by Faina Ryvkin, Frederick T. Greenaway

“…The utility of the extensible systematic force field (ESFF) was tested for copper(II) binding to a 34-amino-acid Cu(II) peptide, which includes five histidine residues and is the putative copper-binding site of lysyl oxidase. …”
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Prediction of Deleterious Nonsynonymous Single-Nucleotide Polymorphism for Human Diseases by Jiaxin Wu, Rui Jiang

“…As a typical type of genetic variation, nonsynonymous single-nucleotide polymorphisms (nsSNPs) occurring in protein coding regions may alter the encoded amino acid, potentially affect protein structure and function, and further result in human inherited diseases. …”
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Structure and Physiological Actions of Ghrelin by Christine Delporte

“…Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n-octanoylation modification on its serine in position 3, catalyzed by ghrelin O-acyl transferase. …”
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Practical Tips for Construction of Custom Peptide Libraries and Affinity Selection by Using Commercially Available Phage Display Cloning Systems by Keisuke Fukunaga, Masumi Taki

“…In the M13 system, Pro or a basic amino acid (especially, Arg) should be avoided at the N-terminus of peptide fused to gp3. …”
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Research progress on energy metabolism regulation in stored platelets by GAO Chengyan, LOU Can, LEI Hang, CAI Xiaohong

“…In maintaining normal function and activation processes, glycolysis, lipid metabolism, and amino acid metabolism play key roles in the energy demand of platelets. …”
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Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets by Yijiang Bei, Linqiang He, Jin Jing, Xiaoming Chen, Fan Yuan, Gaohua Yao, XueYan Ding, Lei Wang, Fan Zhou

“…Different dietary protein levels did not significantly influence the muscle crude protein or amino acid profile (P > 0.05) but significantly affected the contents of some fatty acids (P < 0.05). …”
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Pengaruh Pemberian Glutamin pada Kemampuan Fagositosis Makrofag terhadap Pseudomonas Aeruginosa by Daslina , Eryati Darwin, Aziz Djamal

“…The conclusion from this study is a non-essensial amino acid glutamine has the effect to increase the ability of the body's immune system. …”
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Adropin: a key player in immune cell homeostasis and regulation of inflammation in several diseases by Junmin Wang, Ning Ding, Chong Chen, Simin Gu, Jing Liu, Yanping Wang, Liubing Lin, Yiyuan Zheng, Yong Li

“…Adropin is a secreted peptide encoded by the energy homeostasis-associated gene (ENHO), located chromosome 9p13.3, with a conserved amino acid sequence across humans and mice. Its expression is regulated by various factors, including fat, LXRα, ERα, ROR, and STAT3. …”
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Posttranslational Modifications and the Immunogenicity of Biotherapeutics by Roy Jefferis

“…Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure and function are determined by posttranslational modifications (PTMs), including quality control (QC) in the endoplasmic reticulum (ER) and during passage through the Golgi apparatus. …”
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The key metabolic genes and networks regulating the fruit acidity and flavonoid of Prunus mume revealed via transcriptomic and metabolomic analyses by Xuan Gao, Shuangshuang Wu, Guosheng Lv, Mengyang Wang, Lingxiang Li, Yahui Liu, Feng He, Jiaxin Xiao

“…While the differentially accumulated metabolites were mainly associated with flavone and flavonol biosynthesis and amino acid and carbon metabolism. Moreover, we identified key metabolites, such as citric and succinic acids, which may be central to the development of acidity in Mei fruit, and determined that they are under the regulatory influence of specific genes, including galactinol-sucrose-galactosyltransferase 5, mitogen-activated protein kinase kinase kinase NPK1-like, glutamate receptor, and chalcone isomerase. …”
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Eye development under the control of SRp55/B52-mediated alternative splicing of eyeless. by Weronika Fic, François Juge, Johann Soret, Jamal Tazi

“…B52/SRp55 generates two isoforms of eyeless differing by an alternative exon encoding a 60-amino-acid insert at the beginning of the paired domain. …”
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