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561
Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity
Published 2025-02-01“…Post-translational modifications (PTMs) of these proteins play crucial roles in their function, activity, and interactions with other factors by modifying specific amino acids, thereby enabling a diverse range of protein functions. …”
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562
Discrimination of superficial lymph nodes using ultrasonography and tissue metabolomics coupled with machine learning
Published 2025-01-01“…We observed significant increases in many amino acids, organic acids, lipids, and nucleosides in both lymphoma and metastasis groups, compared to the benign group. …”
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563
Correlation between dominant bacterial community and non-volatile organic compounds during the fermentation of shrimp sauces
Published 2023-01-01“…The quality of salt-fermented shrimp sauce was evaluated in this work by determining the total volatile basic nitrogen (TVB-N), the amino acid nitrogen (AAN), organic acid, 5'-nucleotide and free amino acids (FAA). …”
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564
<i>Ajuga reptans</i> L. Herb Extracts: Phytochemical Composition and Pharmacological Activity Screening
Published 2025-01-01“…In aqueous and aqueous-alcoholic soft extracts of the <i>A. reptans</i> herb, 16 amino acids, 20 phenolics, and 10 volatile substances were identified by HPLC and GC/MS. …”
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565
Harnessing multivariate insights coupled with susceptibility indices to reveal morpho-physiological and biochemical traits in heat tolerance of cotton
Published 2025-01-01“…Biochemical assays underlined the elevated activities of antioxidant enzymes superoxide dismutase (SOD), peroxidase (POD), total free amino acids (TFA), total soluble sugars (TSS), proline content and declined production of total soluble proteins (TSP), which is indicative of oxidative stress. …”
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566
Sheep Manure-Tail Vegetable-Corn Straw Co-Composting Improved the Yield and Quality of Mini Chinese Cabbage
Published 2025-01-01“…Meanwhile, the STS formula also increased the concentrations of polyphenols and essential amino acids of mini Chinese cabbage and also had excellent performance in volatile compounds. …”
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567
Deodorization of Egg White Powder by Ozone Treatment and Underlying Mechanism
Published 2024-12-01“…In addition, fluorescence quenching and molecular docking showed that the major binding force between egg white protein and off-flavor substances was hydrophobic interaction, and their main binding sites were in a hydrophobic cavity composed of amino acids such as Leu66, Lys69, Glu87E, Ala87F, Cys87H, Glu129, Tyr130, Cys133, and Gly320. …”
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568
Preparation of Cod Gelatin Antifreeze Peptides and Its Application of Frozen-Thawed Surimi
Published 2025-02-01“…By determining the molecular weight distribution and amino acid composition of DcAFPs, their basic properties were analyzed. …”
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569
Effects of different protein levels on growth performance and body composition of spotted scat, Scatophagus argus
Published 2025-01-01“…Further studies about amino acids of the diets as well as body compositions should be conducted to elucidate for better dietary formulation of S. argus. …”
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570
Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A
Published 2020-01-01“…The 3D structure of ATL1 was predicted by RaptorX and modeled using UCSF Chimera to compare the differences between the native and the mutant amino acids. Results. Five nsSNPs out of 249 were classified as the most deleterious (rs746927118, rs979765709, rs119476049, rs864622269, and rs1242753115). …”
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571
Whole-Genome Duplication and Purifying Selection Contributes to the Functional Redundancy of Auxin Response Factor (ARF) Genes in Foxtail Millet (Setaria italica L.)
Published 2021-01-01“…SiARFs were categorized into either activators or repressors according to the enrichment of specific amino acids. Intrinsic disorder was featured in the middle regions of ARF activators. …”
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572
Protective mechanism of Coprinus comatus polysaccharide on acute alcoholic liver injury in mice, the metabolomics and gut microbiota investigation
Published 2024-01-01“…Metabolites pathways analysis showed that hepatoprotective effect of CCP was related to energy metabolism, biosynthesis of unsaturated fatty acids, amino acids metabolism and lipid metabolism. Additionally, CCP inhibited an increase in the number of Clostridium perfringens, Enterobacteriaceae and Enterococcus, and a decrease in the number of Lactobacillus and Bifidobacterium in the gut of ALD mice. …”
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573
One-step introduction of the hexafluoroisobutyl group, synthesis of (S)-5,5,5,5',5',5'-hexafluoroleucine, and its incorporation into peptides and proteins
Published 2024-12-01“…In biological systems, it notably corresponds to the side chain of the amino acid leucine. The replacement of this branched chain by the hexafluoroisobutyl group provides a significantly more hydrophobic moiety while maintaining a close global morphology. …”
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574
The Nutritional Composition of Maca in Hypocotyls (Lepidium meyenii Walp.) Cultivated in Different Regions of China
Published 2017-01-01“…The protein content of maca ranged from 9.31% to 21.02% by dry basis of maca powders and Xiaopingba-Y, Yulong-Y, and Pamirs-Y have the higher protein contents. The essential amino acids (EAA) contents ranged from 189.19 to 312.90 mg/g protein. …”
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575
Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions.
Published 2025-01-01“…Using genetic code expansion and incorporation of commercially available unnatural amino acids, we have developed a highly accessible method whereby interactions between biotinylated ubiquitin-like protein (UBL) probes and their binding partners can be stabilised using ultraviolet (UV) light-induced crosslinks. …”
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576
Changes in Flavor Substances of Sauced Beef during Processing Based on the Maillard Reaction
Published 2024-12-01“…Ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) identified 103, 167, and 200 differential metabolites in the CT, F, and CF groups, respectively, and a large number of amino acids, dipeptides, nucleosides, and heterocyclic compounds were produced in the CF group; gas chromatography-mass spectrometry (GC-MS) results showed that CF and F promoted the production of volatile flavor substances in sauced beef. …”
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577
Dietary inulin supplementation improves meat quality and off-flavor of duck meat referring to regulated muscle fiber types and antioxidant capacity
Published 2025-01-01“…Inulin increased the content of umami and sweet amino acids by 2.63 %, which affects the flavor of duck meat. …”
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578
Revealing systematic changes in the transcriptome during the transition from exponential growth to stationary phase
Published 2025-01-01“…., Crp, NtrC, CysB, Cbl) responsible for metabolizing the limiting element; and (iii) the shortage of each limiting element differentially affects the production of amino acids and extracellular polymers. This study demonstrates how the combination of genome-scale datasets and new data analytics reveals the fundamental characteristics of a key transition in the life cycle of bacteria.IMPORTANCENutrient limitations are critical environmental perturbations in bacterial physiology. …”
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579
Integrated transcriptomic and metabolomic analyses elucidate the mechanism by which grafting impacts potassium utilization efficiency in tobacco
Published 2025-01-01“…Metabolome analysis revealed 175 metabolites with significant differences, primarily involving primary metabolites such as amino acids and carbohydrates. Among these, there was an increase in the metabolites levels related to glycolysis, amino acid metabolism, and the TCA cycle pathway in grafted tobacco leaves. …”
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580
Molecular Assessment of Domain I of Apical Membrane Antigen I Gene in Plasmodium falciparum: Implications in Plasmodium Invasion, Taxonomy, Vaccine Development, and Drug Discovery
Published 2022-01-01“…The DNA sequence generated was converted into the matching amino acid sequence using bioinformatic techniques. …”
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