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Alpha synuclein overexpression can drive microbiome dysbiosis in mice
Published 2025-02-01Subjects: Get full text
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
Published 2025-01-01Subjects: Get full text
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Age-dependent alpha-synuclein aggregation and Lewy body formation in Parkinson’s disease
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Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity
Published 2016-01-01Get full text
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Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins
Published 2025-02-01Subjects: “…Alpha-Synuclein…”
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High-Affinity Detection of Alpha-Synuclein by Aptamer-Gold Conjugates on an Amine-Modified Dielectric Surface
Published 2019-01-01“…The therapeutic approach of PD focuses on alpha-synuclein as an important substrate of PD pathology. …”
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Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional studyResearch in context
Published 2025-02-01“…Summary: Background: Synuclein pathology in neurodegenerative diseases, such as Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB), begins years before motor or cognitive symptoms arise. Alpha-Synuclein seed amplification assays (α-syn SAA) may detect aggregated synuclein before symptoms occur. …”
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Decreasing alpha-synuclein aggregation on rotenone-induced adult Zebrafish as Parkinson’s Diseases model by ethanol extraction of Keluwih (Artocarpus camansi) leaves
Published 2023-09-01“…The aim of this study was to evaluate the effect of ethanol extract of A. camansi leaves on the levels of alpha-synuclein in male and female adult zebrafish induced with rotenone. …”
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Prion meeting 2023: implications of a growing field
Published 2024-12-01Subjects: “…Alpha-synuclein…”
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Substantia nigra alterations in mice modeling Parkinson’s disease
Published 2024-11-01Subjects: Get full text
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A review of gut microbiota as a therapeutic approach for Parkinson’s disease
Published 2024-12-01Subjects: “…alpha-synuclein…”
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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model
Published 2025-01-01Subjects: Get full text
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Preventing epileptogenesis by interaction between inositol isomers and proteins
Published 2025-02-01Subjects: “…alpha‐synuclein, 14‐3‐3 theta…”
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Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease
Published 2025-01-01Subjects: Get full text
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Are oligodendrocytes bystanders or drivers of Parkinson's disease pathology?
Published 2025-01-01“…This Unsolved Mystery discusses the limited understanding of oligodendrocytes in PD, highlighting unresolved questions regarding functional changes in oligodendroglia, the role of myelin in nigral dopaminergic neurons, the impact of the toxic environment, and the aggregation of alpha-synuclein within oligodendrocytes.…”
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Analysis on the Susceptibility Genes in Two Chinese Pedigrees with Familial Parkinson's Disease
Published 2010-01-01“…Fifty-one genomic DNA samples extracted from two Chinese pedigrees with FPD, the alpha-synuclein genes (SNCA), the leucine-rich repeat kinase 2(LRRK2), PINK1(PTEN-induced putative kinase 1), PARK7(Protein DJ1), PARK2(Parkinson juvenile disease protein 2), the glucocerebrosidase (GBA), and ATP(Ezrin-binding protein PACE-1), were sequenced by the use of polymerase chain reaction (PCR) technique. …”
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