TLR2 Expression in Relation to IL-6 and IL-1<mml:math alttext="$eta$"> <mml:mi>&#x03B2;</mml:mi> </mml:math> and their Natural Regulators Production by PMN and...

“…In the present study, TLR2 expression and production of IL-1<mml:math alttext="$eta$"> <mml:mi>&#x03B2;</mml:mi> </mml:math> and IL-6 as well as their natural regulators (sIL-1RII, IL-1Ra and sIL-6R<mml:math alttext="$alpha$"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, sgp130, resp) by PMN of peripheral blood in patients with Lyme disease were examined. …”
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Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown by Frank T. Aboagye, Lawrence Annison, Henry Kwadwo Hackman, Maame E. Acquah, Yvonne Ashong, Isaac Owusu-Frimpong, Bill C. Egyam, Sharon Annison, George Osei-Adjei, Samuel Antwi-Baffour

“…The SARS-CoV-2 variants detected were Alpha (64.2%), Delta (22.2%), and Omicron (13.6%). …”
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Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

“…Factor analysis supported a one-factor solution. Cronbach’s alpha was 0.83, indicating internal consistency reliability. …”
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Development and assessment of the health-related quality of life scale for children with hearing loss in China by Jie Liu, Yu-Xiao Wang, Jing Li, Dahong Wu, Guang-xian Zeng, Jing Cheng, Jia-yi Wang, Jian-Zhong Zheng, Lu He

“…Reliability assessment encompassed Cronbach’s alpha coefficient, split-half reliability, and retest reliability measures. …”
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Prevalence of Fabry Disease among Patients with Parkinson’s Disease by Alexandra Lackova, Christian Beetz, Sebastian Oppermann, Peter Bauer, Petra Pavelekova, Tatiana Lorincova, Miriam Ostrozovicova, Kristina Kulcsarova, Jana Cobejova, Martin Cobej, Petra Levicka, Simona Liesenerova, Daniela Sendekova, Viktoria Sukovska, Zuzana Gdovinova, Vladimir Han, Mie Rizig, Henry Houlden, Matej Skorvanek

“…An increased prevalence of Parkinson’s disease (PD) disease has been previously reported in subjects with Fabry disease (FD) carrying alpha-galactosidase (GLA) mutations and their first-line relatives. …”
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A randomized controlled interventional study for analgesic effects of intrathecal versus intravenous dexmedetomidine on subarachnoid anesthesia with hyperbaric bupivacaine by Manu Dadhwal, Anupama Gupta, Ajay Kurian

“…Alpha2 agonists have analgesia and sedative properties when used as adjuvant in regional anesthesia. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…This results in excess accumulation of unpaired alpha-chain gene products leading to reduced red blood cell life span and the development of severe anemia. …”
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Development and psychometric evaluation of a theory of planned behavior model-based instrument for evaluation of determinants of oral health behaviors in mothers of children younge... by Rusul Abdulameer Hadi Al-Sarray, Ahmadreza Shamshiri, Muhammad Alzubidi, Mahdia Gholami, Simin Z. Mohebbi

“…For the internal stability of the tool to keep Cronbach’s alpha values > 0.7 for all domains, we had to omit three questions from attitude, one from subjective norms, and one from perceived behavioral control. …”
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Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress by Giuseppina Palladini, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Stefano Perlini, Andrea Ferrigno, Mariapia Vairetti

“…Serum hepatic enzymes and TNF-alpha were assessed. An increase in gelatinase activity in the NASH model occurred in RL compared with ML. …”
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Coping with sand and dust storms: Developing and validating of an adaptation assessment tool by Shiva Salehi, Ali Ardalan, Abbas - Ostadtaghizadeh, Armin Zareiyan, Gholamreza Garmaroudi, Abbas Rahimiforoushani

“…The reliability of the tool was then calculated using Cronbach's alpha test and the intra -cluster correlation index. …”
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Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer by Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant, Rushikesh Joshi, Sachin Mishra, Anchala Pandey, Dimple Notani, Sanjeev Shukla

“…Hypoxia drives CCCTC-binding factor (CTCF) induction through hypoxia-inducible factor 1-alpha (HIF1α), which promotes EMT, although the underlying mechanisms remain unclear. …”
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Comparative reducing and carbohydrate enzyme inhibitory activities of the root, leaf, and seed of Picralima nitida by Erwin Osiele Onyekachukwu, Aishat Mary Osagie, Sylvia Oghogho Omage, Kingsley Omage, Marshall Arebojie Azeke

“…However, the seed extract had the highest ABTS radical scavenging ability (IC50 = 174.02 ± 0.75 µg/ml) in comparison with the root extract (IC50 = 181.83 ± 1.01 µg/ml) and leaf extract (IC50 = 279.87 ± 1.39 µg/ml). Alpha-amylase and alpha-glucosidase inhibitory properties of the extracts increased steadily with increasing concentration, as that of glibenclamide. …”
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Sustained Intraocular Pressure Rise after the Treat and Extend Regimen at 3 Years: Aflibercept versus Ranibizumab by Alper Bilgic, Laurent Kodjikian, Jay Chhablani, Anand Sudhalkar, Megha Trivedi, Viraj Vasavada, Vaishali Vasavada, Shail Vasavada, Samaresh Srivastava, Deepak Bhojwani, Aditya Sudhalkar

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Comparing the Prognostic Value of PTEN and Akt Expression with the Mitotic Activity Index in Adjuvant Chemotherapy-Treated Node-Negative Breast Cancer patients aged <55 years by Emiel A. M. Janssen, Håvard Søiland, Ivar Skaland, Einar Gudlaugson, Kjell H. Kjellevold, Arne Nysted, Jon-Arne Søreide, Jan P. A. Baak

“…Results: Twenty-one (17%) patients developed distant metastases = DMs (median follow-up: 134 months). p110alpha correlated (p = 0.01) with pAkt but only in PTEN-negatives; pAkt correlated (p = 0.02) with mTOR. …”
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Diospyros mespilifoemis hochst Modulates the Hippocampus and Prefrontal Cortex of Wistar Rat following Lithium chloride pilocarpine-induced Epilepsy by Sunday Yinka Olatunji, Oluwafemi Ezekiel Kale, Oluseyi Abimbola Ogunsola, John Afees Olanrewaju, Ijeoma Esiaba, Taiye Adelodun, Olubunmi Philip Ogunnaike

“…Levels of SOD, MDA, catalase glutamate, GABA, IL-6 and TNF-alpha were assayed using appropriate protocols. Histological and immunohistochemistry tests were done. …”
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Abnormal power and spindle wave activity during sleep in young smokers by Youwei Dong, Yongxin Cheng, Juan Wang, Zhiwei Ren, Yiming Lu, Kai Yuan, Kai Yuan, Fang Dong, Dahua Yu

“…Power spectral analysis and sleep spindle detection are used to analyze EEG activity during sleep.ResultsCompared to the non-smokers, young smokers showed increased alpha power in the frontal and central regions and decreased delta power in the central region. …”
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Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity by Douglas D. Fraser, Douglas D. Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R. Van Nynatten, Gediminas Cepinskas, Gediminas Cepinskas, Haiyan Zheng, Amenah Soherwardy, Devjit Roy

“…Our data suggests that within 48 h of hospital admission, COVID-19 patients undergo a protease storm with significantly elevated neutrophil elastase (p &lt; 0.001) and lymphocyte granzyme B (p &lt; 0.01), while, anti-protease activity is significantly increased, including alpha-1 antitrypsin (AAT; p &lt; 0.001) and alpha-1-antichymotrypsin (ACT; p &lt; 0.001). …”
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Development of an educational and monitoring mobile application for pregnant women in Nigeria by Abdulhammed Opeyemi Babatunde, Abdulhammed Opeyemi Babatunde, Adejumoke Idowu Ayede, Amalia Colangelo, Tuan Dung Nguyen, Abdullahi Tunde Aborode, Charles Umeh, Maria Paula Hernandez, Oluwaseyi Iyanuoluwa Ayede, Oluwatobiloba Oluwadunni Ayede

“…Mobile applications increased the level of knowledge of preeclampsia by 179%. User feedback from alpha testing informed the development of a high-fidelity prototype for beta testing. …”
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Investigating Postoperative Urinary Retention: Risk Factors and Postsurgical Outcomes in Total Joint Arthroplasty by Madeleine J.F. Powers, MSIII, Zachary T. Grace, MD, Barrett B. Torre, MD, Dorothy B. Wakefield, MS, Laura Sanzari, MS, BSN, RN, Matthew J. Grosso, MD

“…Variables analyzed included age, sex, alpha-blocker prescription, operative joint, body mass index, American Society of Anesthesiologists score, Charlson Comorbidity Index classification, and anesthesia type. …”
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Primary Lymphoma of the Liver: A Case Report and Review by Franzjosef Schweiger, Rowen Shinder, Sheldon Rubin

“…The diagnosis of these rare tumours is suggested by the presence of a hepatic mass without lymphadenopathy, splenomegaly or bone marrow involvement, as well as normal carcinoembryonic antigen and alpha-fetoprotein levels. However, histological examination of tissue is essential to confirm the diagnosis. …”
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