Development of a novel instrument to measure Japanese psychiatric nurses’ technological competency as caring in nursing by Yoshiyuki Takashima, Hirokazu Ito, Gil P. Soriano, Yuko Yasuhara, Kyoko Osaka, Savina Schoenhofer, Tetsuya Tanioka

“…Results: The developed instrument comprises 22 items with a 4-factor structure: competency to practice caring and person-centered care (Factor 1); competency to recognize and respond to ethical issues in psychiatry (Factor 2); competency to utilize technology in psychiatry (Factor 3); and competence to practice care for the preservation of human dignity and shared decision making (Factor 4). Cronbach’s alpha for the entire scale was 0.864, while that for factors 1-4 was 0.911, 0.814, 0.773, and 0.64, respectively. …”
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The role of the interleukin family in liver fibrosis by Zixin Zhang, Zixin Zhang, Jiahui Wang, Hui Li, Qun Niu, Qun Niu, Yujing Tao, Yujing Tao, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Haijian Dong, Haijian Dong

“…Relevant studies have demonstrated that effective inhibition of hepatitis B virus (HBV) replication by nucleoside (acid) analogs or polyethylene glycol alpha-interferon can lead to recovery in some patients with hepatitis B liver fibrosis, However, some patients with liver fibrosis do not show improvement, even after achieving a complete serologic and virologic response. …”
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Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis by Salvatore Dimonte, Paywast Jamal Jalal, Hiwa Abdulrahman Ahmad, Safa Bakr Karim, Taib Ahmed Hama Soor, Salar Ibrahim Ali, Muhammed Babakir-Mina, Francesco Greco

“…Moreover, the 2019-nCoV is not closely related to other alpha, beta and gamma human Coronavirus, including MERS-CoV. …”
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Comparative Metabolic Analysis of Different <i>Indica</i> Rice Varieties Associated with Seed Storability by Fangxi Wu, Yidong Wei, Yongsheng Zhu, Xi Luo, Wei He, Yingheng Wang, Qiuhua Cai, Huaan Xie, Guosheng Xie, Jianfu Zhang

“…The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicated that several biosynthesis pathways were involved in the observed metabolite differences, including alpha-linolenic acid metabolism, butanoate metabolism, and propanoate metabolism. …”
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miR-210 in Exosomes Derived from Macrophages under High Glucose Promotes Mouse Diabetic Obesity Pathogenesis by Suppressing NDUFA4 Expression by Feng Tian, Ping Tang, Zhilian Sun, Ruifen Zhang, Danhua Zhu, Junying He, Jixing Liao, Qinghua Wan, Jie Shen

“…Macrophage-derived exosomes impaired glucose uptake and mitochondrial CIV complex activity and suppressed NADH dehydrogenase ubiquinone 1 alpha subcomplex 4 (NDUFA4) expression in 3T3-L1 adipocytes. miR-210 directly bind with mRNA sequences of NDUFA4 gene. …”
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Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel‐Like Structures in Hydrogels for Tissue Engineering by Chinmoy Patra, Amey Rayrikar, Ganesh Wagh, Florian Kleefeldt, Kaveh Roshanbinfar, Florian Cop, Iva Nikolic, Mirko H. H. Schmidt, Amparo Acker‐Palmer, Süleyman Ergün, Felix B. Engel

“…Notably, the angiogenesis‐associated integrins itgav and itgb3.1 are coexpressed with nephronectin a in the region of the caudal vein plexus and posterior somites; nephronectin binds to integrin alpha‐V/integrin beta‐3.1 (ITGAV/ITGB3.1), and itgav morphants phenocopy nephronectin a mutants. …”
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Acute and chronic effects of physical exercise on atherosclerosis, kynurenine pathway, endothelial function and inflammation in patients with coronary artery disease: a clinical tr... by Eliete Bouskela, Gabriela Andrade Paz, Marcus VDS Rangel, Caio Luan Farias, André Luiz Conveniente Soares, Erica Langner, Tatiana Teixeira, Patrícia M L Dutra, Paulo Farinatti, Maria das Graças C Souza, Juliana P Borges

“…Levels of KP metabolites (TRP, KYN, kynurenic acid and quinolinic acid), inflammatory cytokines (interleukin-6, tumour necrosis factor-alpha and interferon-gamma), T-cell subpopulations and soluble adhesion molecules (soluble P-selectin, soluble vascular cell adhesion molecule-1 and soluble intercellular adhesion molecule-1) will be assessed via ELISA, flow cytometry and multiplex assays, respectively. …”
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Enhancing Food Security via selecting Superior Camelina (Camelina sativa L.) parents: a positive approach incorporating pheno-morphological traits, fatty acids composition, and Toc... by Amin Ebrahimi, Hamzeh Minaei Chenar, Sajad Rashidi-Monfared, Danial Kahrizi

“…The fatty acid C18:2 displayed a markedly strong positive correlation with alpha-tocopherol (0.99**), while C18:3 exhibited positive correlations with gamma-tocopherol (0.98**) and total tocopherol (0.98**). …”
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Nicotinamide Mononucleotide Restores NAD⁺ Levels to Alleviate LPS-Induced Inflammation via the TLR4/NF-κB/MAPK Signaling Pathway in Mice Granulosa Cells by Mehboob Ahmed, Umair Riaz, Haimiao Lv, Muhammad Amjad, Sohail Ahmed, Shaokat Ali, Muhammad Usman Ghani, Guohua Hua, Liguo Yang

“…The results of this experiment demonstrated that LPS had negative effects on GCs in term of reduced viability and proliferation rates and upregulated the production of pro-inflammatory cytokines, including interleukin-1 beta (IL-1β), interleukin-6 (IL-6), cyclooxygenase-2 (Cox-2), and tumor necrosis factor-alpha (TNF-α). Notably, the levels of NAD⁺ and NAD⁺/NADH ratio in GCs were reduced in response to inflammation. …”
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Mechanism of dexmedetomidine protection against cisplatin induced acute kidney injury in rats by Zeng-lu Zheng, Jun-wei Ma, Yi Luo, Gui-jin Liang, Shi-jie Lei, Ke-jin Yan, Hai-bing Meng, Xiu-juan Liu

“…In addition, four serum biochemical indices were measured: histopathological damage in rat kidneys was detected; levels of inflammatory factors, interleukin (IL)-1β, IL-18, IL-6, and tumor necrosis factor alpha, in kidney tissue homogenate of rats were assessed through enzyme-linked immunosorbent assay (ELISA); and levels of NLRP-3, caspase-1, cleaved caspase-1, gasdermin D (GSDMD), and GSDMD-N in kidney tissues of rats were determined via western blotting.Results Dex treatment reduced nephromegaly and serum clinical marker upregulation caused by CP-induced AKI. …”
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A Review of Treatment Methods and Available Therapies for Individuals with ADHD by Zuzanna Gałuszka, Natalie Papachristoforou, Daria Michałka, Monika Makar, Tomasz Bartuś, Żaneta Góra, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…The analysis focuses on stimulant and non-stimulant medications, including methylphenidate, amphetamines, atomoxetine, and alpha-2 agonists, with regional variations in treatment guidelines. …”
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Mechanism of <italic>Hedyotis Diffusa</italic> in Treatment of Osteosarcoma based on Network Pharmacology and Molecular Docking by Qin LIU, Xinwei DUAN, Xihai LI

“…After topology analysis to PPI, the eight core genes that indicate a close interaction were estrogen receptor 1(ESR1), JUN, and RAC-alpha serine/threonine-protein kinase(AKT1), G1/S-specific cyclin-D1(CCND1), FOS, mitogen-activated protein kinase 1(MAPK1), cellular tumor antigen p53(TP53)and MYC. …”
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Enhancing growing rabbit heat stress resilience through dietary supplementation with natural antioxidants by Ibrahim Talat El-Ratel, Aml Mekawy, Sara H.M. Hassab, Sameh Abdelnour

“…The serum Immunoglobulin G (IgG) was significantly increased, while tumor necrosis factor alpha (TNF-α), interleukin-4 (IL-4), and interferon gamma (IFN-γ) were decreased by all feed additives (P < 0.05). …”
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Post-treatment of rat aflatoxicosis by camel milk and silymarin by Nahla H. Hassaneen, Shabaan A. Hemeda, Abeer F. El Nahas, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Zuhair M. Mohammedsaleh, Sabreen E. Fadl, Eman M. El-Diasty, Hader I. Sakr, Hader I. Sakr

“…The evaluation was done through measuring leukocyte count, liver function tests, carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), ferritin, and testosterone. …”
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Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15 by Syh-Jae Lin, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Tzu Lee, Wen-I Lee, Ji-Yih Chen, Jing-Long Huang

“…We sought to examine the perforin and granzyme B expression, interferon-gamma (IFN-γ), and tumor-necrosis factor-alpha (TNF-α) production and CD107a degranulation of NK and NKT-like cells from SLE patients and their regulation by IL-15. …”
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A Resource-Efficient Multi-Entropy Fusion Method and Its Application for EEG-Based Emotion Recognition by Jiawen Li, Guanyuan Feng, Chen Ling, Ximing Ren, Xin Liu, Shuang Zhang, Leijun Wang, Yanmei Chen, Xianxian Zeng, Rongjun Chen

“…First, Discrete Wavelet Transform (DWT) is applied to extract five brain rhythms, i.e., delta, theta, alpha, beta, and gamma, from EEG signals, followed by the acquisition of multi-entropy features, including Spectral Entropy (PSDE), Singular Spectrum Entropy (SSE), Sample Entropy (SE), Fuzzy Entropy (FE), Approximation Entropy (AE), and Permutation Entropy (PE). …”
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Validity and reliability of the Malay language Perception Towards Smoking Questionnaire (BM-PTSQ) among secondary school adolescents: Further validation using Confirmatory Factor A... by Kuang Hock Lim, Yoon Ling Cheong, Hui Li Lim, Kee Chee Cheong, Mohd Hazilas Mat Hashim, Ali Aman Marine, Yong Kang Cheah, Jia Hui Lim, Sumarni Mohd Ghazali

“…In addition, we also employed EFA, confirmatory factor analyses (CFA), and Cronbach's alpha to evaluate the construct validity and reliability of the BM-PTSQ. …”
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Dutch Validation of the Self-Evaluation of Negative Symptoms Scale (SNS) by Tim van Brouwershaven, Anika Poppe, Gerdina Hendrika Maria Pijnenborg, André Aleman, Nynke Boonstra, Shiral Gangadin, Sonia Dollfus, Wim Veling, Stynke Castelein, Jan Alexander de Vos, Edith Liemburg, PHAMOUS-researchers, Lisette van der Meer

“…Internal consistency was assessed by Cronbach’s alpha. Confirmatory factor analysis (CFA) was used to evaluate the construct validity of the five subscales of the SNS. …”
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Factors influencing healthcare workers’ perceived compliance with infection prevention and control standards, North Bank East region, The Gambia, a cross-sectional study by Sheriffo M.K. Darboe, Sandra A. Darfour-Oduro, Godsway Edem Kpene, Abou Kebbeh, Nuha Fofana, Manjally Ndow, Kawsu Sanyang, Dwomoh Duah, Alfred Edwin Yawson, Ernest Kenu, Harriet Affran Bonful

“…Descriptive statistics, chi-square, and logistic regression were done at a 95% confidence limit and an alpha level of 0.05. A p-value of 0.05 was considered statistically significant. …”
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Preliminary evidence of immune infiltration and neutrophil degranulation in peripheral blood of non-obese OSA patients related to cognitive decline by Qingqing Liu, Yanru Ou, Ting Liu, Yuming He, Xiangming Quan, Ruoyun Ouyang, Zhihui Shi

“…The relevant genes, including upregulated defensin alpha 4 (DEFA4), haptoglobin (HP), survivin (BIRC5), and suppressed interferon gamma (IFNG) expression were detected. …”
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