Chronic restraint stress affects the diurnal rhythms of gut microbial composition and metabolism in a mouse model of depression by Yue Wang, Peijin Cui, Maolin Cao, Ling Ai, Li Zeng, Xue Li, Dan Chen, Fang Gong, Liang Fang, Chanjuan Zhou

“…Results CRS mice exhibited depressive-like behaviours after 4 weeks of restriction. Alpha- and beta-diversity analyses revealed that the microbial composition in control and CRS mice oscillated throughout the day. …”
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Tear metabolomics reveals novel potential biomarkers in epithelial herpes simplex keratitis by Jinyu Zhang, Zhenning Wu, Yangqi Zhang, Kaili Wu, Xiaoyi Li, Shiyou Zhou

“…The changed metabolites were enriched in these pathways: arginine and proline metabolism, phospholipid biosynthesis, alpha linolenic acid and linoleic acid metabolism, retinol metabolism. …”
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Self-assessment of didactic performance of psychology and education professors in Mexico and Peru by Aldo Bazán-Ramírez, Walter Capa-Luque, Roberto Chávez-Nava, Mónica C. Dávila-Navarro, Homero Ango-Aguilar, Edmundo Hervias-Guerra, Catalina Bello-Vidal

“…The reliability for the overall score of the questionnaire as well as for the interactive episodes evidenced McDonald’s ordinal alpha and omega coefficients ≥0.94 and H coefficient ≥ 0.95. …”
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The Psychometric Properties of the Persian Migraine-Specific Quality of Life Questionnaire Version 2.1 in Episodic and Chronic Migraines by Alireza Zandifar, Samaneh Sadat Masjedi, Faraidoon Haghdoost, Fatemeh Asgari, Navid Manouchehri, Mahboobeh Banihashemi, Mohammad Reza Najafi, Abbas Ghorbani, Behzad Zolfaghari, Ali Gholamrezaei, Vahid Shaygannejad, Mohammad Saadatnia

“…Internal consistency (Cronbach alpha) and test-retest reproducibility (intraclass correlation coefficients) were used to assess reliability. …”
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Ameliorative effect of curcuminoids in liver fibrosis rat model via regulating GIPC1 gene and modulating MMP-8/TIMP-3 balance mediated by miR-483-5p by Rana Mostafa Adel, Sara Mostafa Kamal, Eman Adel Sherif, Sara Hatem El-shafiey

“…We aimed to explore CURC’s effect on declining the inflammatory cytokines TNF-α (tumor necrosis factor-alpha), IL-6 (interleukin-6), TGF-β1 (transforming growth factor beta1), regulating GIPC1 expression, and adjusting MMP-8/TIMP-3 balance mediated by miRNA-483-5p (microRNA-483-5p) in TAA (thioacetamide)-induced liver fibrotic albino Wistar rat model. …”
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Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice by Brecht Attema, Montserrat A. de la Rosa Rodriguez, Evert M. van Schothorst, Sander Grefte, Guido JEJ. Hooiveld, Sander Kersten

“…Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. …”
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The extensive cultivation of Pyropia haitanensis along the coastal areas influences the ecological dynamics of nearby intertidal mudflat pond water by Peihao Liu, Qijun Luo, Shanshan Zhu, Juanjuan Chen, Rui Yang, Tingting Niu, Tiegan Wang, Peng Zhang, Haimin Chen

“…The dynamic diversity patterns and structure of microbial communities were determined by 16S and 18S rRNA sequencing, and the environmental factors were measured.ResultsIn the offshore aquaculture area, the cultivation of P. haitanensis increased the dissolved oxygen and pH, decreased inorganic nutrients, reduced the alpha diversity of bacteria, established the dominance of Proteobacteria, but did not influence the composition of microeukaryotes. …”
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DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3 by Wenjian Yao, Linlin Shang, Yinghao Wang, Lei Xu, Yu Bai, Mingyu Feng, Xiangbo Jia, Sen Wu

“…Abstract Background The RAR-related orphan receptor alpha (RORA), a circadian clock molecule, is highly associated with anti-oncogenes. …”
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Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway by Lingchao Miao, Meng Sam Cheong, Haolin Zhang, Haroon Khan, Haroon Khan, Hongxun Tao, Yuxiao Wang, Wai San Cheang

“…Chronic oral administration of purslane extract ameliorated colon shortening syndrome and reduced bowel inflammation in HFD-induced obese mice through suppression of the toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling pathway to downregulate TLR4, myeloid differentiation factor 88 (MyD88), Ser32 phosphorylation of NF-κB inhibitor alpha (IκBα), and Ser536 phosphorylation of NF-κB p65 expression levels, thereby inhibiting the pro-inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-6 levels.ConclusionThe present study supports the anti-inflammatory potential of purslane extract for modulating bowel inflammation under obesity through inhibition of the TLR4/NF-κB signaling pathway.…”
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Development and validation of the “Adjustment Disorder Scale for Medically Ill Patients - ETAM” by Juan Pablo Zapata-Ospina, Natalia Rodríguez, Ayda Margarita Rodríguez, Jenny García-Valencia, Mercedes Jiménez-Benítez, Nicolás Martínez-Ramos, Diana Restrepo Bernal, Ana Lucía Gallego, Carolina Gómez, Luis Fernando Tabares, Carlos Cardeño-Castro, Daniel Camilo Aguirre-Acevedo

“…Internal consistency was adequate, with McDonald’s omega of 0.95 and Cronbach’s alpha between 0.82 and 0.92 for its dimensions. ETAM had high test-retest reliability (intraclass correlation coefficient of 0.98). …”
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Evaluation of the Diversities in the Inflammatory Responses in Cats With Bacterial and Viral Infections by Songul Erhan, Bengu Bilgic, Ezgi Ergen, Mert Erek, Elif Ergul Ekiz, Mukaddes Ozcan, Mehmet Erman Or, Banu Dokuzeylul, Erdal Matur

“…Total and differential leukocyte counts, C‐reactive protein (CRP), transforming growth factor beta (TGF‐β), interleukin‐6 (IL‐6), tumour necrosis factor‐alpha (TNF‐α), interleukin‐1 beta (IL‐1β) and interleukin‐10 (IL‐10) concentrations were assessed in the blood samples collected from sick and healthy animals. …”
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Navigating the fear: assessing nursing students’ concerns and preventive practices in response to Monkeypox in Egypt by Shaimaa Mohamed Amin, Doaa El Demerdash, Mona Metwally El-Sayed, Tasneem Ragab Ahmed Salama, Mohamed Gamal Elsehrawy, Mohamed Hussein Ramadan Atta

“…Reliability was confirmed with Cronbach’s alpha values ranging from 0.87 to 0.94. Data analysis included descriptive statistics, Spearman correlation, and multiple linear regression using SPSS Version 23. …”
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Inclusive educational process at the university: Theoretical and experimental model of teachers' psychological readiness by V. Z. Kantor, Yu. L. Proekt

“…The survey results were analysed qualitatively and quantitatively using the Cronbach Alpha coefficient, Shapiro-Wilk, Kolmogorov-Smirnov, Mann-Whitney tests, and the median test applying the Pearson test. …”
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Understanding the vaginal microbiome among women with different genotypes of human papillomavirus infection in remote Andaman islands by Rehnuma Parvez, Santhiya Vijayakumar, Alwin Vins, Sudha Ramaiah, Anand Anbarasu, Lipika Biswas, Nisha Beniwal, Harpreet Kaur, Nagarajan Muruganandam

“…To assess diversity, samples were rarefied to 49,000 sequence reads per sample, and alpha and beta diversity metrics were calculated.ResultsThe study analyzed the presence of 21 assigned phyla, with Firmicutes, Actinobacteria, Bacteriodetes, and Proteobacteria emerging as the predominant taxa. …”
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Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time by André Luiz Musmanno Branco Oliveira, Gabriel Dias Rodrigues, Gabriel Dias Rodrigues, Bruno Moreira Silva, Philippe de Azeredo Rohan, Pedro Paulo da Silva Soares

“…Spectral analysis of R-R intervals and systolic BP revealed cardiovascular autonomic modulation in the low- (LF; 0.04–0.15 Hz) and high-frequency (HF; 0.15–0.40 Hz) bands and alpha-index (α–LF) assessed spontaneous baroreflex sensitivity (BRS). …”
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Utilizing Hip Abduction Strength to Body-Weight Ratios in Return to Sport Decision-Making After ACL Reconstruction by Steven Higbie, Jacquelyn Kleihege, Brian Duncan, Walter R. Lowe, Lane Bailey

“…Data were analyzed using univariate general linear models with an alpha level of .05. # Results Of the 528 enrolled patients, 364 (68.9%) demonstrated a low strength to BW ratio. …”
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A brief instrument measuring the water, sanitation and hygiene domain of menstrual health among women who inject drugs. by Alhelí Calderón-Villarreal, Lourdes Johanna Avelar Portillo, Daniela Abramovitz, Shira Goldenberg, Shawn Flanigan, Penelope J E Quintana, Alicia Harvey-Vera, Carlos F Vera, Gudelia Rangel, Steffanie A Strathdee, Georgia L Kayser

“…<h4>Results</h4>Among 125 (124 cis-female and 1 trans-male) PWID that reported menstruating, our 'MH WASH Domain Scale-12' was reliable (Cronbach's alpha = 0.81, McDonald's Omega total = 0.83) and valid. …”
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Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia—An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy by Patrícia Quelhas, Rui Oliveira, Carlos Kieling, Sandra Vieira, Jorge dos Santos

“…The detrimental effect of HIF-1alpha pathway activation over early native liver survival was confirmed, although independently from PC or cytoplasmic tubulin features.…”
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Evaluating strategies for global respiratory pandemic control at ports: a modelling study by Gregory Gan, Jue Tao Lim, Tong Guan, Sharon Esi Duoduwa, S Balakumar, Janhavi A, Borame L Dickens

“…To assess different infection parameters, we explored three variants (Alpha, Delta and Omicron), four prevalences (0.1%, 0.5%, 1% and 2%) and three quarantine compliances (50%, 90% and 100%).Results Across the prevalences with no intervention, our modelled simulations estimate that approximately 3%, 15%, 28% and 47% of crews are infected, totalling around 9400, 44 900, 82 600 and 141 300 infections. …”
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HEMPSEED AND COTTONSEED OILS IN THE ACCESSIONS FROM THE VIR COLLECTION AS SOURCES OF FUNCTIONAL FOOD INGREDIENTS by S. V. Grigoryev, T. V. Shelenga, K. V. Illarionova

“…The content of the omega-6 linoleic acid in hemp accessions reached 64.2%; omega-3 alpha-linolenic acid, 27.1%; monounsaturated oleic acid, 14.0%. …”
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