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2401
Quality of Life Assessment in Diabetic Patients Using a Validated Tool in a Patient Population Visiting a Tertiary Care Center in Bhubaneswar, Odisha, India
Published 2020-01-01“…The final questionnaire had an overall Cronbach’s alpha value of 0.894 (subscale: 0.55 to 0.85), showing high internal consistency in the current study population. …”
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2402
Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes
Published 2013-01-01“…Secretion levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), NF-κB nuclear translocation, NF-κB activation, Stat3 phosphorylation, and peroxisome proliferator-activated receptor alpha (PPARα) mRNA and protein levels, as well as the cell proliferation ability were measured at the end of the treatment and after 24 hours of recovery. …”
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2403
H. Wendl Leaf Metabolites Potentiate the Radiosensitivity of Hepatocellular Carcinoma Through Ki67 and PARP Inhibition
Published 2025-01-01“…Likewise, the tumor markers alpha-fetoprotein (AFP) and gamma-glutamyl transferase (GGT) levels were considerably reduced in HCC rats. …”
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2404
Validação transcultural da versão moçambicana da escala de autoeficácia em Educação Física inclusiva
Published 2025-02-01“…Resultados: Os valores dos índices de bondade e de ajustamento do modelo atestam a fidignidade da versão Moçambicana (NFI=0,83; TLI=0,91; CFI=0,92; IFI=0,92; RMSEA =0,074). Os valores de Alpha de Cronbach de cada uma das variáveis observadas variaram entre 0,786 e 0,823 para Deficiência Intelectual (DI), entre 0,732 e 0,826 para Deficiência Física (DF) e entre 0,729 e 0,847 para Deficiência Visual (DV), demonstrando valores bons de consistência interna. …”
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2405
Bifidobacterium adolescentis-derived nicotinic acid improves host skeletal muscle mitochondrial function to ameliorate sarcopenia
Published 2025-02-01“…Additionally, NAD+ activation enhances the silent-information-regulator 1 (SIRT1)/peroxisome-proliferator-activated-receptor-γ-coactivator 1-alpha (PGC-1α) axis, stimulating mitochondrial biogenesis and promoting oxidative metabolism in slow-twitch fibers, ultimately improving muscle function. …”
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2406
Effects of Adipose-tissue Derived Mesenchymal Stem Cells on PBMCs in Co-culture with HeLa Cell Line
Published 2024-04-01“…Materials and Methods: The effect of MSC cells on proliferation, apoptosis, and gene expression of the cytokines tumor necrosis factor alpha (TNF-α), transforming growth factor beta (TGF-β), interleukin (IL)-4, IL-2, and interferon-γ in PBMCs cultured together with HeLa cells was investigated using flow cytometry and real-time polymerase chain reaction (PCR), respectively. …”
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2407
Stress factors among physiotherapy students at a university in Gauteng, South Africa
Published 2025-01-01“…Data were collected through an online anonymised self-administered questionnaire. The Cronbach alpha coefficients for each subscale were 0.99 for physical, 0.72 for interpersonal relationships, 0.85 for academic and 0.81 for environment. …”
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2408
Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors
Published 2010-01-01“…We demonstrated that a significant percentage of hASCs differentiated into a CAF-like myofibroblastic phenotype (e.g., expression of alpha smooth muscle actin and tenascin-C) when exposed to conditioned medium from the human breast cancer lines MDAMB231 and MCF7. …”
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2409
Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats
Published 2025-01-01“…In irradiated rats, CNPs also showed anti-neuroinflammatory effects by reducing brain interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α), and nuclear factor-kappa B (NF-ĸB) levels (P < 0.05). …”
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2410
Natural language processing to identify suicidal ideation and anhedonia in major depressive disorder
Published 2025-01-01“…Interrater reliability (IRR) was calculated using Krippendorff’s alpha. A novel transformer architecture-based NLP model was trained on clinical notes to recognize linguistic patterns and contextual cues. …”
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2411
Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women
Published 2017-01-01“…The panel of adipokines included interleukin- (IL-) 6, IL-8, IL-1β, adipsin, lipocalin-2/neutrophil gelatinase-associated lipocalin (ngal), TNF-alpha, monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, hepatocyte growth factor, resistin, leptin, adiponectin, and nerve growth factor. …”
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2412
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice
Published 2025-01-01“…In addition, we measured the levels of certain inflammatory cytokines (Tumour Necrosis Factor-alpha (TNF-α), Interleukin-1 (IL-1), Interleukin-6 (IL-6), and Interleukin-10 (IL-10), looked at the expression of tight junction proteins (Zonula Occludens-1(ZO-1), Claudin-1), measured mucin-2 levels, and looked into changes in the gut flora. …”
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2413
Serum cardiac and inflammatory biomarker levels following chemotherapy among female patients with breast cancer attending at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiop...
Published 2025-01-01“…An Elecsys 2010 Troponin-T immunoassay analyzer was used to measure serum levels of cardiac troponin T (cTnT), creatinine kinase-myocardial band (CK-MB), C-reactive protein (CRP), and R and D systemic luminex performance assays were used to measure serum Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF- α). Data were analyzed using the SPSS version 23 package, and a p-value < 0.05 was considered statistically significant. …”
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2414
Bioinformatics and Expression Profiling of the DHHC-CRD S-Acyltransferases Reveal Their Roles in Growth and Stress Response in Woodland Strawberry (<i>Fragaria vesca</i>)
Published 2025-01-01“…A complementation assay in yeast PAT mutant <i>akr1</i> and auto-S-acylation assay of one FvPAT (FvPAT19) confirmed its enzyme activity where the Cys in the DHHC motif was required. An AlphaFold prediction of the DHHC and the mutated DHHC155S of FvPAT19 provided further proof of the importance of C155 in fatty acid binding. …”
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2415
Adaptation Studies of the Aggression and Victimization Scales for Elementary School Children
Published 2013-07-01“…CSBS-SR’s and CSEQ-SR’s test-retest reliability were found to be .64 and.80 and internal consistency assessed by Cronbach Alpha were found to be .84 and .90 respectively. …”
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2416
Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease
Published 2015-01-01“…Serum calcium, phosphorus, 25(OH)-vitamin D, parathyroid hormone (PTH), erythrocyte sedimentation rate, high-sensitivity C-reactive protein, interleukin- (IL-) 17, IL-6, IL-1β, interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), plasmatic and urinary NGAL, and 24 h albuminuria and proteinuria were measured before and 24 h after an intravenous bolus of paricalcitol (5 mcg). …”
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2417
Screening and Early Diagnosis of Hepatocellular Cancer and Optimization of Diagnostic Imaging Techniques: A Review and Conclusion of the Expert Panel
Published 2023-02-01“…Screening for HCC in high-risk groups (cirrhosis of any etiology, patients with chronic viral hepatitis B and patients with F3 liver fibrosis) should be organized as regular (every 6 months) liver ultrasound in combination with determination of the serum alpha-fetoprotein (AFP) level. At an AFP level of ≥ 20 ng/ml, even in the absence of changes according to ultrasound data, it is advisable to perform MRI with a hepatospecific contrast agent (gadoxetic acid) which makes it possible to detect very small focal liver lesions. …”
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2418
A Study on Canopy Volume Measurement Model for Fruit Tree Application Based on LiDAR Point Cloud
Published 2025-01-01“…In the domain of point cloud feature extraction, an improved Alpha Shape algorithm is proposed for extracting point cloud contours. …”
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2419
Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor‐Repopulating Cells of Intrahepatic Cholangiocarcinoma via Disrupting Cytoskeleton by P‐Selectin/PSGL1 N‐Glycosylation Bloc...
Published 2025-01-01“…Sulfarotene induces retinoic acid receptor alpha (RARɑ) translocation from the cytoplasm to the nucleus, suppressing P‐selectin expression at the transcriptional level. …”
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2420
Estimación sustentable del riesgo cardiovascular con las tablas predictivas de Gaziano sin laboratorio
Published 2022-06-01“…A estas personas se les realizó la prueba de confiabilidad Alpha de Cronbach. Se les preguntó si tenían otros hábitos modificables (frecuencia de ejercicios físicos, consumo de bebidas alcohólicas, si realizan meriendas entre comidas y si le adiciona sal a estas). …”
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