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2321
Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Published 2016-01-01“…The aim of this study was to investigate the changes of regulatory T cells (Treg), interleukin-6 (IL-6), IL-10, transforming growth factor-β (TGF-β), and tumor necrosis factor-alpha (TNF-α) in patients with type 2 diabetes mellitus (T2DM). …”
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2322
Competências de escrita manual e processamento sensorial em crianças dos 6 aos 7 anos e 11 meses
Published 2024-12-01“…O questionário demonstrou excelente consistência interna, com valores de Alpha de Cronbach superiores a 0,80. Para avaliar a validade discriminativa por grupos conhecidos, foram realizadas comparações entre géneros e anos escolares. …”
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2323
Lean Transformation Success: The Role of Management and Employee Engagement
Published 2023-09-01“…Tools: As the initial step of the research, using Cronbach's alpha, it was concluded that obtained set of items in the group are closely related and measure a particular aspect. …”
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2324
CGDINet: A Deep Learning-Based Salient Object Detection Algorithm
Published 2025-01-01“…The results show that CGDINet outperforms other mainstream significance object detection models in evaluation metrics such as <inline-formula> <tex-math notation="LaTeX">${\mathrm {maxF}}_{\mathrm {\beta }}$ </tex-math></inline-formula>, <inline-formula> <tex-math notation="LaTeX">$\mathrm {S}_{\mathrm {\alpha }}$ </tex-math></inline-formula>, and MAE, with almost no increase in computational cost (FLOPs) and parameters. …”
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2325
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial–mesenchymal transition
Published 2024-12-01“…This study tested the hypothesis that the Krüppel-like factor 4 (KLF4)/miR-101/Collagen alpha-1X (COL10A1) axis could inhibit epithelial-mesenchymal transition (EMT) and renal fibrosis after AKI in a mouse model of ischemia-reperfusion (I/R)-induced renal fibrosis and HK-2 cells by gene silencing, overexpression, immunofluorescence, immunohistochemistry, real-time quantitative PCR, Western blotting, dual-luciferase reporter assay, fluorescence in situ hybridization (FISH) and ELISA. …”
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2326
Cross-cultural adaptation: South African Gestational Diabetes Mellitus Knowledge Questionnaire
Published 2025-01-01“…For internal consistency, Cronbach’s alpha values were 0.534 for the Afrikaans version, 0.434 for the English version and 0.621 for the isiXhosa version. …”
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2327
Örgütsel Çatışma Çözüm Yöntemleriyle Duygusal Zeka Arasındaki İlşki: Bir Tasarım Mühendisliği Örneği
Published 2014-02-01“…Kullanılan ölçeklerin güvenilirlik değerleri için Cronbach Alpha sayılarına bakılmışve duygusal zeka anketi için .95, çatışma yönetimi anketi için ise .88 gibi yüksek alfa katsayılarına ulaşılmıştır. …”
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2328
Development and validation of a questionnaire for table tennis teaching in physical education
Published 2025-01-01“…The last study was a confirmatory factor analysis (to establish the final number of items and their structure. The ordinal alpha values ranged from 0.65 to 0.72, obtaining an average value of 0.70, indicating coherence between the measurement of the items. …”
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2329
Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy
Published 2016-01-01“…ASPP2 knockdown facilitated the proliferation and migration of RPE cells and enhanced the expression of mesenchymal markers such as alpha smooth muscle actin, fibronectin, and ZEB1. …”
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2330
Precision fetal cardiology detects cyanotic congenital heart disease using maternal saliva metabolome and artificial intelligence
Published 2025-01-01“…Pathway analysis showed significant alterations in Arachidonic Acid, Alpha-linoleic acid, and Tryptophan metabolism indicating significant lipid dysfunction in cyanotic CHD. …”
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2331
Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation
Published 2025-02-01“…Results Direct contact of CAL-1 and IMR-90 cells under ER stress conditions led to increased expression of fibronectin and alpha-smooth muscle actin (α-SMA). This effect required expression of the ER stress signaling sensor protein kinase R-like ER kinase (PERK) in pDCs and was observed only upon direct contact between both cell types. …”
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2332
Simple hypertrophic tonsils have more active innate immune and inflammatory responses than hypertrophic tonsils with recurrent inflammation in children
Published 2020-06-01“…In TH group, elevated expression was observed in the innate immune mediators, including retinoic acid-inducible gene I (RIG-I), interferon alpha (IFN-α), mitochondrial antiviral-signaling protein (MAVS), NLR family pyrin domain containing 3 (NLRP3), toll-like receptor (TLR) 4 and TLR7. …”
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2333
Achieving chronic hepatitis B functional cure: Factors and potential mechanisms
Published 2025-01-01“…Achieving the loss of hepatitis B surface antigen (HBsAg), either with or without seroconversion to hepatitis B surface antibody (HBsAb), is regarded as a functional cure and the optimal goal for addressing CHB, and can be achieved through various approaches, including induction with nucleos(t)ide analogues (NAs), induction with pegylated interferon alpha (PegIFNα), and spontaneous clearance of HBsAg. …”
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2334
Evaluating the therapeutic effect of different forms of silymarin on liver status and expression of some genes involved in fat metabolism, antioxidants and anti‐inflammatory in old...
Published 2024-11-01“…All groups receiving silymarin showed a decrease in liver malondialdehyde content, expression of fatty acid synthase, tumour necrosis factor alpha, interleukin 6 (IL‐6) genes in the liver, and hepatic steatosis than the control, except those fed the PSM100 diet. …”
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2335
Unexpected species diversity in the understanding of selenium-containing soil invertebrates
Published 2025-01-01“…Environmental factors such as Se concentration, water content, and pH were strongly associated with species beta diversity of soil invertebrates in Se-rich areas, reshaping their distribution and abundance, while alpha diversity remained relatively stable. Among these, Se notably emerges as the primary regulatory factor increasing soil invertebrate diversity. …”
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2336
Cross-Cultural Validity, Reliability, and Psychometric Properties of the Persian Version of the Scales for Outcomes in Parkinson’s Disease-Psychosocial Questionnaire
Published 2014-01-01“…The highest and lowest correlation coefficients of internal consistency were reported for item 7 on “asking for help” (r=0.765) and item 5 on “sexual problems” (r=0.553). Cronbach’s alpha reliability coefficient of the entire scale was 0.87 (95% CI: 0.83–0.90). …”
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2337
Smad2/3 Upregulates the Expression of Vimentin and Affects Its Distribution in DBP-Exposed Sertoli Cells
Published 2015-01-01“…In a previous study, we found that peroxisome proliferator-activated receptor alpha (PPARα) influenced the distribution of vimentin by affecting its phosphorylation in DBP-exposed SCs. …”
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2338
Prevalence of nasopharyngeal bacteria during naturally occurring bovine respiratory disease in commercial stocker cattle
Published 2025-01-01“…No differences were observed in the alpha diversity matrices based on day or NumTrt (P > 0.05). …”
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2339
Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-κB Pathway
Published 2018-01-01“…Inflammation is a natural process of the innate immune system, accompanied with the increase in the level of proinflammatory mediators, for example, nitric oxide (NO) and prostaglandin (PGE2); cytokines such as interleukin 6 (IL-6), interleukin 1β (IL-1β), and tumor necrosis factor alpha (TNFα); and enzymes including inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) via the activation and nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) subunit p65 due to the phosphorylation of inhibitory protein, IκBα. …”
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2340
Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation
Published 2019-01-01“…In both A549 cells and mouse lung tissues, further study showed that Rg1 perfusion significantly suppressed the secretion of inflammatory cytokines including tumor necrosis factor- (TNF-) alpha and interleukin- (IL-) 6 and relieved cells from ER stress as supported by decreased expression of marker proteins via upregulating sirtuin 1 (SIRT1). …”
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