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2281
Cytokines in Liver Cirrhosis (Their Importance in Assessing Activity and Decompensation)
Published 2023-11-01“…The study of the content of pro-inflammatory and anti-inflammatory cytokines in the blood serum of patients with Class A liver cirrhosis showed, that levels of tumour necrosis factor alpha (TNF-α), interleukin-2, interleukin-6 were statistically higher compared to healthy individuals, while the concentration of anti-inflammatory interleukin-10 was lower (30.7 ± 4.7 pg/mL) in comparison with the control group. …”
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2282
Bi-Hormonal Endocrine Cell Presence Within the Islets of Langerhans of the Human Pancreas Throughout Life
Published 2025-01-01“…There was no change in the relative presence of alpha- or beta-cells with advancing age, but delta-cell presence showed a decline with age (R<sup>2</sup> = 0.59, <i>p</i> < 0.001). …”
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2283
In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol
Published 2025-03-01“…Rather, they prime the macrophage, potentiating LPS-stimulated TNF alpha secretion and key pro-inflammatory enzymes. …”
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2284
Analysis of the Multilevel Impact of Social Network Quality on Personality Dimensions in Purchasing
Published 2024-06-01“…The reliability of the questionnaire was confirmed using Cronbach’s alpha and the CR index, while its validity was confirmed using content, convergent, and discriminant validity methods. …”
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2285
Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells
Published 2022-01-01“…The levels of miR-206 and gap junction protein alpha 1 (GJA1) in EPCs and vascular tissues of DVT mice were detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). …”
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2286
Enhancing patient education on the role of tibial osteotomy in the management of knee osteoarthritis using a customized ChatGPT: a readability and quality assessment
Published 2025-01-01“…The responses were evaluated for quality using the DISCERN criteria and readability using the Flesch Reading Ease Score (FRES) and Flesch-Kincaid Grade Level (FKGL).ResultsThe native ChatGPT-4 model scored a mean DISCERN score of 38.41 (range 25–46), indicating poor quality, while “The Knee Guide” scored 45.9 (range 33–66), indicating moderate quality. Cronbach's Alpha was 0.86, indicating good interrater reliability. …”
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2287
Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis in Suckling Lambs with Intrauterine Growth Retardation
Published 2020-01-01“…Compared with CON lambs, relative protein 53 (P53), apoptosis antigen 1 (Fas), Bcl-2-associated X protein (Bax), caspase-3, cytochrome C, tumor necrosis factor alpha (TNF-α), nuclear factor kappa-B (NF-κB) p65, and NF-κB pp65 protein levels were higher (P<0.05) in liver from IUGR lambs, whereas those in liver from IUGR lambs under Arg or NCG treatment were lower than those in IUGR lambs. …”
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2288
Unusual open-system behaviour revealed by LA-MC-ICP-MS U–Th dating of coral and coralline algae bio-carbonates
Published 2023-06-01“…The precision on the dates is comparable to those of alpha-spectrometry (around 7.6% on average), but the possibility of multiple in-situ analyses offers other advantages. …”
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2289
Distinct gut microbial signature and altered short chain fatty acid metabolism at disease onset in a rat preclinical model of superimposed preeclampsia
Published 2024-12-01“…At disease onset on GD14, the fecal gut microbiome of SHRSP showed a lower alpha diversity and significant differences in beta diversity when compared with control animals. …”
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2290
Validation of the Perceived hope scale in Arabic-speaking adults living in Gaza in the midst of war, destruction and death
Published 2025-01-01“…Results The fit indices of the one-factor solution reached the standards of good model fit, with excellent internal consistency (Cronbach’s alpha = 0.90). Invariance was established in our sample at the configural, metric and scalar levels in terms of gender groups. …”
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2291
Measurement through structural equations of the self-concept instrument in high-school students
Published 2025-01-01“…Data analysis utilized SPSS version 25 and AMOS 24 software to ensure reliability and validity through structural equation modeling.ResultsThe AF-5 demonstrated high reliability, with a Cronbach's alpha of 0.854. Gender differences were observed, with females scoring higher in emotional self-concept and males excelling in physical self-concept. …”
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2292
Evaluation of Cardioprotective Effect of 3,5,3′-Tri-iodo-L-thyronine in Isoproterenol-Induced Cardiotoxicity
Published 2011-01-01“…Lower heart weight, upregulation of cardiac myosin heavy chain alpha (MHC-α), and reduced inflammatory cell infiltration, myonecrosis, vacuolar changes, and a trend toward normal cardiac muscle fiber architecture in microscopic examination of cardiac tissue further support the cardioprotective effect of T3.…”
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2293
Development of a psychological frailty index: results from the China health and retirement longitudinal study
Published 2025-02-01“…The PFI demonstrated satisfactory internal consistency (Cronbach’s alpha = 0.764) and criterion validity (rho = 0.806). …”
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2294
Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants
Published 2015-01-01“…However, a completely new surgical approach providing safe handling of the photosensor array had to be developed. The Retina Implant Alpha IMS consisting of a subretinal microphotodiode array and cable linked to a cochlear-implant-like ceramic housing was introduced via a retroauricular incision through a subperiosteal tunnel above the zygoma into the orbit using a specially designed trocar. …”
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2295
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling
Published 2025-01-01“…Using a cytokine cocktail containing IL-17A, interferon-gamma and tumour necrosis factor-alpha to produce a psoriasis-like phenotype, a role for ALOX15B in human epidermal keratinocyte inflammation was investigated. siRNA-mediated silencing of ALOX15B increased CCL2 expression and secretion. …”
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2296
Measuring effective indicators for waste disposal in order to assess the sustainable environment: application of fuzzy approach
Published 2023-09-01“…., economic, technical, environmental, and social, based on their respective propensity.In the second step, a statistical analysis questionnaire was distributed among the study population, and Cronbach's alpha was explained for all four main factors of the study. …”
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2297
Translation, cultural adaptation and validation of the SCHNOS in French
Published 2019-03-01“…Internal consistency was high, with Cronbach’s alpha of 0.93 for F-SCHNOS-O and 0.95 for F-SCHNOS-C. …”
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2298
Investigating the inflammatory effect of microplastics in cigarette butts on peripheral blood mononuclear cells
Published 2025-01-01“…The purpose of this study was to analyze the immune response of human peripheral blood mononuclear cells (PBMCs) when exposed to cigarette filter microfibers, measuring the secretion of the inflammatory cytokines TNFα (tumor necrosis factor-alpha) and IL-6 (interleukin-6). In this study, we examined how used cigarette cellulose acetate microfibers affect the viability of peripheral blood mononuclear cells in an appropriate culture medium at three concentrations: 50, 100, and 200 µg/ml. …”
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2299
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2300
Variation in Botryosphaeriaceae from Eucalyptus plantations in YunNan Province in southwestern China across a climatic gradient
Published 2020-10-01“…Isolates were identified by comparing DNA sequences of the internal transcribed spacer ribosomal RNA locus (ITS), partial translation elongation factor 1-alpha (tef1), β-tubulin 2 (tub2) and DNA-directed RNA polymerase II subunit (rpb2) genes, and combined with their morphological characteristics. …”
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