Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry by Tapasyapreeti Mukhopadhyay, Arulselvi Subramanian, Venencia Albert, Anand Kumar, Tushar Sehgal, Sulekha Karjee, Harprasad Pati

“…The platelet distribution width, mean platelet volume, platelet-large cell ratio, plateletcrit, and immature platelet fraction were 9.4 ± 2.7 fL, 8.7 ± 1.2 fL, 16.9% ± 8.9%, 0.6% ± 0.3%, and 4.4% ± 3.9%, respectively. The r-time, k-time, alpha angle, and maximum amplitude were 15 ± 0.3 min, 2.1 ± 0.4 min, 65.2° ± 2.3°, and 76.1 ± 10.1 mm, respectively. …”
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Preliminary study on mercury pollution affecting soil bacteria near a mercury mining area by Jianxiong Du, Yili Yuan, Jianfeng Li, Shuqing Zhang, Yuxiang Ren

“…The sequencing results indicated a significantly greater diversity of the soil bacterial community in SMO2, SMO20, and SMO650 (relative high mercury contents) than in SMO300 and SMO500 (relative low mercury contents). Alpha diversity analysis revealed that the soil bacterial community diversity in SMO2 and SMO20 significantly exceeded that in SMO30, SMO500, and SMO650. …”
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Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease by Hongjun Ba, Yao Wang, Lili Zhang, Huishen Wang, Zhan-Peng Huang, Youzhen Qin

“…KD diagnostic biomarkers, including the alkaline phosphatase (ALPL), endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 2 (EDEM2), and histone cluster 2 (HIST2H2BE), were discovered (AUC=1.000) and verified utilizing the GSE73461 dataset (AUC=1.000). …”
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Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota by Kai Kang, Yue Sun, Dan Pan, Bing Chang, Li-Xuan Sang

“…Then, 16S rRNA sequencing of the large intestinal content was performed, and analysis of alpha diversity and beta diversity showed that the richness of the gut microbiota was decreased in the DSS group compared to the control group and restored after NAM treatment. …”
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Psychometric accuracy of the Dutch Child and Adolescent Trauma Screener by Lieke H. Kooij, Irma M. Hein, Cedric Sachser, Samantha Bouwmeester, Madelief Bosse, Ramón J. L. Lindauer

“…The KJTS showed excellent reliability (alpha = .92) on both selfreport and caregiver report. …”
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Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models by Sébastien Soubeyrand, Paulina Lau, Ruth McPherson, Ruth McPherson

“…COP1 downregulation reduced hepatic nuclear factor-4 alpha (HNF4A) abundance and function, as assessed by a lower abundance of key HNF4A targets, reduced APOB secretion, and reporter assays. …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…We used Discovery Studio software to analyze the folding free energy of variant proteins, and the AlphaFold database to analyze structural alterations in mutant proteins. …”
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Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells by Zohre Miri-Lavasani, Shukoofeh Torabi, Roya Solhi, Bahareh Shokouhian, Parvaneh Afsharian, Zahra Heydari, Abbas Piryaei, Zahra Farzaneh, Nikoo Hossein-khannazer, Hamidreza Aboulkheyr Es, Ensieh Zahmatkesh, Andreas Nussler, Moustapha Hassan, Mustapha Najimi, Massoud Vosough

“…Hepatocyte nuclear factor 4 alpha (HNF4α) is the key hepatogenesis transcription factor and its upregulation may decrease the invasiveness of cancerous cells by suppressing epithelial-mesenchymal transition (EMT). …”
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An Autonomous Underwater Vehicle Navigation Technique for Inspection and Data Acquisition in UWSNs by Arif Wibisono, Md. Jalil Piran, Hyoung-Kyu Song, Byung Moo Lee

“…Furthermore, in the inspection and data acquisition mission in UWSN simulated as node points (o) in pink, AUV (&#x002A;) in blue effectively follows the predetermined points while acquiring data, as indicated by green lines (-) within just 5 seconds, achievable by increasing the value of <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula> (angle of attack) of the target node to reduce delay time. …”
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ESTRATEGIAS DIDÁCTICAS DIRIGIDAS A LOS DOCENTES DE EDUCACIÓN FÍSICA PARA FAVORECER EL DESARROLLO DE LAS CAPACIDADES COORDINATIVAS DE LOS EDUCANDOS DEL SUBSISTEMA DE EDUCACIÓN INICI... by Darwin Joel Orduz Albarracin

“…., la recolección de datos se efectuó a través de la técnica de la encuesta, y como instrumentos la aplicación de un cuestionario el cual fue validado a través del juicio de expertos y la confiabilidad se determinó según el coeficiente de Alpha de Cronbach. La investigación finalmente concluyó que los docentes especialistas  presentan  insuficiente conocimiento sobre las estrategias didácticas innovadoras donde se emplee los métodos y estilos globales de enseñanza, asimismo, se evidenció aplicación de los métodos deductivo e inductivo principalmente, obviando los otros métodos que también pueden ser utilizados. …”
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Vaginal hysterectomy versus vaginal assisted NOTES hysterectomy (VANH): a protocol for a randomised controlled trial by Merel Kimman, Ilse Bekkers, Lynn Hoen, Huib A A M van Vliet, Nicol A C Smeets, Anne Damoiseaux, Martine M L H Wassen

“…We calculated a sample size of 124 women assuming 27% SDD difference with an alpha of 0.05 and power of 0.8. A total of 83 patients will be included in the VANH-group and 41 patients in the VH-group, using an enrolment ratio of 2:1. …”
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Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection by Yuexin Wang, Qiuli Yang, Yingjie Dong, Likun Wang, Zhiyuan Zhang, Ruiying Niu, Yufei Wang, Yujing Bi, Guangwei Liu

“…In addition, Piezo1 integrates magnesium signalling and the SIRT2-hypoxia-inducible factor-1 alpha (HIF1α)-dependent pathway to orchestrate reciprocal M1 and M2 macrophage lineage commitment through neutrophil-derived NET DNA. …”
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A psychometric appraisal of a revised preparedness for medication administration questionnaire in final-year undergraduate nursing students: a secondary analysis by Susan Irvine, Sharon Andrew, Christina Aggar, Nicola Whiteing, Anecita Gigi Lim, Brett Williams

“…The final revised version of the questionnaire titled the Preparedness for Medication Administration Revision2 (PMAR2) contained 16 items loading onto one of the 2 factors titled Clinical Reasoning and Confidence to Practice Safely. Cronbach alpha coefficients for the factors were .89 to .95, respectively. …”
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Detection of The TNFSF Members BAFF, APRIL, TWEAK and Their Receptors in Normal Kidney and Renal Cell Carcinomas by Vassiliki Pelekanou, George Notas, Katerina Theodoropoulou, Marilena Kampa, Dimitrios Takos, Vassilia-Ismini Alexaki, Jelena Radojicic, Frank Sofras, Andreas Tsapis, Efstathios N. Stathopoulos, Elias Castanas

“…Therapeutic approaches targeting TNF-alpha have shown limited efficacy, while anti-TRAIL (TNFSF10) antibodies have shown enhanced activity. …”
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Morphological and molecular changes in renal tissue following experimental unilateral ureteral obstruction in rat kidneys by Tuncer KUTLU, Huseyin OZKAN, Ziya YURTAL, Ufuk KAYA, Mehmet GUVENC

“…By the second day, hyperemia, increased tumor necrosis factor-alpha (TNFα) gene expression, and elevated malondialdehyde (MDA) levels were evident. …”
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Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts by Mariko Miura, Hideki Kitaura, Fumitoshi Ohori, Kohei Narita, Jiayi Ren, Takahiro Noguchi, Aseel Marahleh, Jinghan Ma, Angyi Lin, Ziqiu Fan, Itaru Mizoguchi

“…Abstract Tumor necrosis factor-alpha (TNF-α) is a significant cytokine that regulates bone resorption under inflammatory conditions. …”
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Karhunen–Loeve orthogonal decomposition method for problems of EEG assessment of patients with migraine by Egorov, Evgenij Nikolaevich, Zhuravlev, Maksim Olegovich, Runnova, Anastasia Evgenevna, Evstropov, Maksim Arkad`evich, Redzhepova, Alena Садуллаевна

“…It has been shown that there is a relationship between the number of significant modes and the power of the alpha rhythm in electroencephalography signals, and the spatial localization of this effect in the occipital region of the brain can be traced. …”
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Non-Steroidal Anti-Inflammatory Drugs Are Inhibitors of the Intestinal Proton-Coupled Amino Acid Transporter (PAT1): Ibuprofen and Diclofenac Are Non-Translocated Inhibitors by Carsten Uhd Nielsen, Sebastian Jakobsen, Maria L. Pedersen

“…The molecular interaction between NSAIDs and hPAT1 was investigated using an AlphaFold2 model and molecular docking. <b>Results:</b> NSAIDs such as ibuprofen, diclofenac, and flurbiprofen inhibited proline uptake via hPAT1, with IC₅₀ values of 954 (logIC₅₀ 2.98 ± 0.1) µM, 272 (logIC₅₀ 2.43 ± 0.1) µM, and 280 (logIC₅₀ 2.45 ± 0.1) µM, respectively. …”
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The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator? by Daniel S. Smyk, Athanasios Mavropoulos, Giorgina Mieli-Vergani, Diego Vergani, Marco Lenzi, Dimitrios P. Bogdanos

“…CD1d-restricted iNKT cells are regulators of immune responses and produce cytokines that may be proinflammatory (such as interferon-gamma (IFN-γ)) or anti-inflammatory (such as IL-4). iNKT cells also appear to play a role in B cell regulation and antibody production. Alpha-galactosylceramide (α-GalCer), a derivative of the marine sponge, is a potent stimulator of iNKT cells and has been proposed as a therapeutic iNKT cell activator. …”
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Vaginal flora in HPV infection: a cross‑sectional analysis by Peining Dou, Feng Fang, Rongqiu Qin, Jingsong Nie, Xiaoyan Chen, Xiaoyan Yin, Yiding Wang, Shengying Shi

“…The vaginal microbial communities of both groups were analysed for diversity and differences to explore their association with HPV infection.Results The abundance of Lactobacillus was found to be reduced, while Gardnerella vaginalis was significantly more prevalent in the HPV + group. In terms of alpha diversity indices, the Shannon index (P = .0036) and Simpson index (P = .02) were higher in the HPV + group compared to the HPV − group, indicating greater community diversity in the HPV + group. …”
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