From fibrosis to granuloma: drug induced systemic sarcoidosis-like reaction after rituximab in a patient with primary Sjögren’s syndrome by Rui Rua Coelho, Sara Xavier Pires, José Ricardo Brandão, Inês Furtado

“…Drug induced sarcoidosis-like reaction (DISR) is a systemic granulomatous reaction, which is histopathologically identical to primary sarcoidosis - mostly described after the use of biologics like tumour necrosis factor alpha antagonists but also anti-CD20 (rituximab). …”
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GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

“…Growth differentiation factor 15 (GDF15) can suppress appetite and regulate energy balance through binding to glial cell-derived neurotrophic factor receptor alpha-like (GFRAL). In order to develop a novel, effective treatment for cachexia, we generated a GDF15-targeting VHH nanobody, GB18–06, that was able to bind GDF15 with high affinity. …”
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Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study by Mohamed I. Selim, Tarek El-banna, Fatma Sonbol, Walaa A. Negm, Engy Elekhnawy

“…Using immunohistochemical investigations, the percentage of the immunoreactive cells significantly decreased after using monoclonal antibodies of the tumor necrosis factor-alpha and interleukin six. So, A. maxima may be considered a new candidate for the development of new antibacterial medications. …”
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Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs by Abbas A Hamzah, Zainab I Ibrahim

“…The blood samples were collected from all animal groups at day zero before pneumoniae induction and 3, 6, and 14 days post infection  for total and differential white blood cell count ‎(WBCs) and tumor necrosis factor-alpha (TNF-α) assessments. Additionally, on days 6 and 14 post-exposure, trachea and lung tissue samples were harvested for macroscopic and microscopic pathological changes evaluation. …”
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Two sexually compatible monokaryons from a heterokaryotic Lentinula edodes strain respond differently to heat stress by Yuan Guo, Wenyu Jiao, Yajie Zhang, Meiting Tan, Qi Gao, Yu Liu, Shouxian Wang

“…The differentially accumulated metabolites (DAMs) of both strains were enriched in the glycerophospholipid metabolism, alpha-linolenic acid metabolism, biosynthesis of cofactors, etc, but were regulated differently in each strain. …”
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Identifying enablers for a circular healthcare supply chain: An integrated fuzzy DEMATEL-MMDE approach with hesitant information by Deepak Agrawal, Sumit Gupta, Chandni Dusad, M.L. Meena, G.S. Dangayach, Sandeep Jagtap

“…This paper identifies the enablers of a circular healthcare supply chain (CHSC) through a comprehensive analysis of cause and effect, interrelationships, and priorities using integrated alpha-level sets based on the fuzzy DEMATEL-MMDE approach with hesitant information. …”
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Theoretical Study of the Quadruple Gamma Transitions of Radioactive Radon and Radium Isotopes Based on Half-Life by Duaa Abed Salim, Waleed Jabbar Mhana, Hadeel Ghali Ishnayin, Khalid Hadi Mahdi

“… Background: This study investigated multiple aspects of radon and radium’s nuclear properties since they are heavy, radioactive elements that may emit alpha, beta, and gamma radiation, which is connected to cancer and poses a risk to the environment. …”
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The Swallowing Clinical Assessment Score in Parkinson’s Disease (SCAS-PD) Is a Valid and Low-Cost Tool for Evaluation of Dysphagia: A Gold-Standard Comparison Study by Larissa L. Branco, Sheila Trentin, Carla Helena Augustin Schwanke, Irenio Gomes, Fernanda Loureiro

“…Internal consistency was calculated by Cronbach’s alpha. Results. Fifty-one percent of patients were classified with dysphagia. …”
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Chronic hepatitis B and risk of kidney involvement by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

“…Moreover, renal disease may be caused by medications used for CHB treatment, e.g. direct nephrotoxicity of adefovir or tenofovir, alpha interferon-induced glomerulonephritis, etc. …”
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Carbonic Anhydrase IX Targeted Polyaspartamide fluorescent Probes for Tumor imaging by Zhang Y, Liu F, Shao C, Huang J, Yan G

“…The contrast-enhanced fluorescent imaging has been applied for non-invasive diagnosis of cancers using tumor-targeting fluorescent probes.Methods: The carbonic anhydrase IX targeted polyaspartamide fluorescent compounds (SD-PHEA-NI) were synthesized by incorporating a tumor-targeting group of sulfadiazine (SD) and N-butyl-4-ethyldiamino-1,8-naphthalimide (NI) into water-soluble carriersof poly-α,β-[N-(2-hydroxyethyl)-L-aspartamide] (PHEA). …”
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Designing a Model of Effective Factors on Creative Cultural Industries in Iran by Abbas Ghaedamini Harouni, Mehrdad Sadeghi Deh Cheshmeh, Sadegh Sadeghi Deh Cheshmeh, Narjes Mohsenifar

“…Both validity questionnaires were confirmed, and Cronbach's alpha coefficient measured its reliability above 0.70.Findings: The Delphi identification test was used to identify the influential factors and was screened in two stages. …”
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Assessment of Factors Affecting Time to Recovery from COVID-19: A Retrospective Study in Ethiopia by Anteneh Mengist Dessie, Sefineh Fenta Feleke, Denekew Tenaw Anley, Rahel Mulatie Anteneh, Zelalem Animut Demissie

“…P value with 95% CI for the hazard ratio was used for testing the significance at alpha 0.05. Results. Six hundred twenty-two cases followed, and 540 observations developed an event at the end of the follow-up. …”
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Role of Career Counselling in Medical Profession: Perceptions of Medical Students by Hina Ahmed, Abdullah Yousaf, Muhammad Ahmed, Muhammad Tauqeer Akhtar

“…After receiving formal IRB approval, data was collected via self-designed google forms and WhatsApp groups from MBBS students in their first to final academic year who volunteered to participate after piloting with Cronbach Alpha score of 0.81. After collecting data, SPSS software version 26 was utilized for analysis. …”
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Cultural adaptation, translation and validation of the conflict in adolescence dating relationship inventory (CADRI) in the Greek language. by Esperanza Barroso-Corroto, Juan Manuel Carmona-Torres, José Alberto Laredo-Aguilera, Ángel López-Fernández-Roldan, Carlos Navarrete-Tejero, Evangelia Kartsoni, Antonios Christodoulakis, Athina Patelarou, Michail Zografakis-Sfakianakis

“…The internal consistency and reliability were good (>0.7), with a Cronbach's alpha of 0.889 for the violence perpetrated subscale and 0.925 for the violence suffered subscale, indicating strong correlations between the total item scores. …”
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Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from <i>Taenia solium</i> Using Computational and Bioinformatics Tools by César Sánchez-Juárez, Roberto Flores-López, Lluvia de Carolina Sánchez-Pérez, Ponciano García-Gutiérrez, Lucía Jiménez, Abraham Landa, Rafael A. Zubillaga

“…The workflow involved modeling and refining the 3D structure from the sequence using the AlphaFold algorithm and all-atom molecular dynamics simulations with an explicit solvent. …”
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University social responsibility and knowledge management for a tax culture: Perception of internal stakeholders of tax advisory centers in Peru by Joberth Vargas-Figueroa, Melva Linares-Guerrero, Sindulfo Javier Diaz-Angulo, Maria Jeanett Ramos-Cavero, Franklin Cordova-Buiza

“…Judges validated it using Aiken’s V and Cronbach’s Alpha reliability test, obtaining a result of 0.921. …”
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Genetic Signatures of Contrasted Outbreak Histories of “Candidatus Liberibacter asiaticus”, the Bacterium That Causes Citrus Huanglongbing, in Three Outermost Regions of the Europe... by Olivier Pruvost, Karine Boyer, Frédéric Labbé, Marine Weishaar, Anaïs Vynisale, Claire Melot, Cécile Hoareau, Gilles Cellier, Virginie Ravigné

“…Huanglongbing can be caused by three species of the phloem‐limited alpha‐proteobacterium, “Candidatus Liberibacter,” which are transmitted by psyllids. …”
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ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells by Lijing Qin, Geng Tang, Ruirui Gui, Yanming Yang, Li Wang, Weiqiang Xu, Hongyuan Tian, Lei Yu, Xiangshan Yang, Zhicheng Wang

“…Abstract Identifying novel targets for molecular radiosensitization is critical for improving the efficacy of colorectal cancer (CRC) radiotherapy. Alpha-thalassemia/mental retardation X-linked (ATRX), a member of the SWI/SNF-like chromatin remodeling protein family, functions in the maintenance of genomic integrity and the regulation of apoptosis and senescence. …”
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Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects by Takashi Kobayashi, Takaomi Kessoku, Michihiro Iwaki, Asako Nogami, Masato Yoneda, Satoru Saito, Yoshie Yamana, Yosuke Nishitani, Hiroshige Kuwahara, Atsushi Nakajima

“…Messenger RNA levels for the pro-inflammatory cytokines, interleukin-1 beta, and tumor necrosis factor-alpha showed no significant changes in the small intestine; however, their expressions significantly decreased in the colon. …”
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Comparative Protective Effects of N-Acetylcysteine, N-Acetyl Methionine, and N-Acetyl Glucosamine against Paracetamol and Phenacetin Therapeutic Doses–Induced Hepatotoxicity in Rat... by Tahia H. Saleem, Nagwa Abo El-Maali, Mohammed H. Hassan, Nahed A. Mohamed, Nashwa A. M. Mostafa, Emaad Abdel-Kahaar, Azza S. Tammam

“…Biochemical assays of malondialdehyde (MDA), nitric oxide (NO), reduced glutathione (GSH), total thiols, and alpha-fetoprotein (AFP) in liver homogenates and serum assays of ALT, AST, 8-hydroxy guanine (8-OH-Gua), and AFP were done. …”
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