Exploring patient-centered barriers to hemophilia care in Southern Nigeria: Study Protocol by Eguzo K, Ekwere T, Kirikareye B, Okoye H, Egharevba P, Oluoha C

“…Whereas the average years in practice for the HCPs was 13±6 years and had encountered about 20 patients (IQR: 6, 32) with hematologic disorders in the previous month. A Cronbach's alpha of 0.92 (PLwH Survey) and 0.91 (HCP survey) was obtained for the surveys, indicating excellent internal consistency. …”
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Intra-oral approach for excision of an unusual cystic mass in a 12-year-Old girl: A case report by Nasem Jamal Yousef, Issa Saad, Marwan Al-Raeei, Chadi Azmeh, Maya Saad, Zeina Darwich

“…Nonsurgical treatments like alpha-interferon, calcitonin, and corticosteroids have been described, and their advantages may be worth considering. …”
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Predictive factors for clinical cure in the treatment of HBeAg(−) chronic hepatitis B or compensated cirrhosis: a prospective observational study by Yan-Qing Lv, Ru-Hua Guo, Kun-Yu Liu, Jia-Jie Li, Hui-Fan Ji

“…BackgroundSequential or combined treatment with nucleos(t)ide analogs (NAs) and pegylated interferon alpha-2b (Peg-IFN-α-2b) can improve the clinical cure rate. …”
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In silico characterisation of the avocado WAK/WAKL gene family with a focus on genes involved in defence against Phytophthora cinnamomi by Aaron Harvey, Aaron Harvey, Noëlani van den Berg, Noëlani van den Berg, Velushka Swart, Velushka Swart

“…The predicted proteins from these genes were modelled with AlphaFold2, and structural similarity across different rootstocks, as well as their binding affinity for oligogalacturonides, were assessed. …”
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Revealing the impact of tadalafil-loaded proniosomal gel against dexamethasone-delayed wound healing via modulating oxido-inflammatory response and TGF-β/Macrophage activation path... by Nermin A Helmy, Elsayed A Abdel Aziz, Mustafa Abd El Raouf, Reda M S Korany, Doaa A Mansour, Sara M Baraka, Arwa A Hassan, Eman Gomaa, Mennatullah M Faisal, Walaa A A Basha, Esraa M Fahmy, Rashed A Alhotan, Anam Ayyoub, Shaimaa Selim

“…The TAD-loaded proniosomal gel successfully antagonized the impacts of DEX by dampening MDA production, and enhancing total antioxidant capacity, coupled with modulation of inflammatory-related genes, inducible nitric oxide synthase, tumor necrosis factor-alpha, interleukin-1β, and matrix metalloproteinase 9, during all healing stages (p < 0.05). …”
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Development of a Japanese version of the patient perceptions of deprescribing – Short form by Mio Kushibuchi, Kenya Ie, Masaki Takahashi, Amy M. Linsky, Steven M. Albert

“…Confirmatory factor analysis of the Japanese version of SF‐PPoD revealed satisfactory structural validity with two‐dimensional structure, “Motivation for Deprescribing” and “Primary Care Physician Relationship.” Cronbach's alpha showed good internal consistency, and test–retest demonstrated acceptable intra‐rater reliability. …”
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Recent advances in nanotechnology for Parkinson’s disease: diagnosis, treatment, and future perspectives by Virendra Kumar Yadav, Seshathiri Dhanasekaran, Nisha Choudhary, Deepak Nathiya, Vishal Thakur, Rachna Gupta, Sheersha Pramanik, Pankaj Kumar, Nishant Gupta, Ashish Patel

“…This review provides insights into the pathophysiology of Parkinson’s disease, highlighting the mechanisms of neurodegeneration, the role of alpha-synuclein, and the disruption of dopaminergic pathways. …”
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Deciphering the fungal symphony: unveiling the fungal dynamics during the fermentation of traditional Chinese strong-flavor Daqu by Lina Zhao, Wenjing Zhang, Yuting Niu, Xiaohan Chen, Jiuyang Guo, Ying Wu, Ying Wu, Xuan Li, Shaobin Gu, Shaobin Gu, Shaobin Gu

“…The results showed that the alpha and beta diversity of fungal community were significantly different during Daqu fermentation. …”
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Nanobody-thioesterase chimeras to specifically target protein palmitoylation by Chien-Wen Kuo, Caglar Gök, Hannah Fulton, Eleanor Dickson-Murray, Samuel Adu, Emily K. Gallen, Sheon Mary, Alan D. Robertson, Fiona Jordan, Emma Dunning, William Mullen, Godfrey L. Smith, William Fuller

“…Using a thioesterase fused to a nanobody directed against the Ca(v)1.2 beta subunit we reduce palmitoylation of the Ca(v)1.2 alpha subunit, modifying the channel’s voltage dependence and arrhythmia susceptibility in stem cell derived cardiac myocytes. …”
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Modeling COVID-19 dynamics in the Basque Country: characterizing population immunity profile from 2020 to 2022 by Bechir Naffeti, Zeineb Ounissi, Akhil Kumar Srivastav, Nico Stollenwerk, Joseba Bidaurrazaga Van-Dierdonck, Maíra Aguiar

“…In the intermediate phase, multiple smaller outbreaks emerged as restrictions were relaxed and new variants, such as Alpha and Delta, appeared. During this period, reinfection rates reached $$20\%$$ 20 % , and seroprevalence increased to $$32\%$$ 32 % . …”
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Not all is lost: resilience of microbiome samples to freezer failures and long-term storage by M. Fabiola Pulido Barriga, James W. J. Randolph, Sydney I. Glassman

“…In conclusion, our study highlights that beta-diversity is more robust than alpha-diversity and fungi are more resilient to freezer failure than bacteria. …”
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Psychometric properties of the Arabic version of the Forgotten Joint Score usage in total hip arthroplasty by Waleed Albishi, Nasser M. AbuDujain, Orfan Arafah, Ibrahim S. Alshaygy, Abdulaziz Almaawi, Zyad A. Aldosari, Mohammed N. Alhuqbani, Omar A. Aldosari, Saad M. Alangari

“…To assess the test-retest reliability, 72 people took the Ar-FJS test twice. Results Cronbach’s alpha (Internal Consistency) of the Ar-FJS-12 was 0.957 and the intraclass correlation coefficient (ICC) was 0.931 indicating high reliability. …”
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Psychometric properties of the health literacy questionnaire tested in Vietnamese adults with chronic diseases by Thi Thuy Ha Dinh, Ann Bonner

“…Confirmatory factor analyses (CFA) testing nine one-factor models were fitted to test the structure of each scale, and a nine-factor model tested the hypothesized structure of the HLQ, followed by the calculation of scale reliability using Cronbach’s alpha. Results No item had floor effects, and only eight items showed ceiling effects. …”
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The Collection of Rhizosphere Microorganisms: its importance for the study of associative plant-bacterium interactions by O. V. Turkovskaya, S. N. Golubev

“…This group includes nitrogen-fixing soil alpha-proteobacte-ria of the genus Azospirillum, which form the core of the IBPPM collection. …”
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Factors influencing compassion satisfaction and compassion fatigue among nurses: a study in a tertiary hospital by Sarah Sharmala Nadarajan, Ping Lei Chui, Wan Ling Lee, Noor Hanita Zaini

“…The data were collected over a period of 6 months via online distribution of the Personal Information Form, Copenhagen Psychosocial Questionnaire (COPSOQ) version III and Professional Quality of Life (ProQOL) version V questionnaires. The Cronbach’s alpha internal consistency of the questionnaire scales was mostly acceptable and above 0.75. …”
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Pipeline for development of acylated peptide based CGRP receptor antagonist with extended half-life for migraine treatment by Jens Bjelke Kristensen, Lisbeth Elster, Morten Lundh, Borja Ballarín-González, Flora Alexopoulou, Martin Kræmer, Ditte Marie Jensen, Ulrike Leurs, Jens Christian Nielsen, Henrik H. Hansen, Kristian A. Haanes, Matilda Degn

“…The disease has neurovascular origin and migraine attacks can be elicited by vasodilative neuropeptides such as alpha calcitonin gene-related peptide (αCGRP). Antagonizing CGRP actions in migraine patients has proven clinically efficient. …”
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Acceptance and adoption determinants of telemedicine in public healthcare institutions by Kokisa E. Phorah, Lovemore Motsi

“…In order to ensure that the instrument was accurate, a pilot study was carried out prior to the main investigation. Both the alpha and power values were set at 0.05 for the statistical analysis. …”
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Leptonic dipole operator with $$\Gamma _2$$ Γ 2 modular invariance in light of Muon $$(g-2)_\mu $$ ( g - 2 ) μ by Takaaki Nomura, Morimitsu Tanimoto, Xing-Yu Wang

“…Supposing the phase of our model parameter $$\delta _{\alpha }$$ δ α for the electron to be of order one, we have estimated the upper-bound of $$\mathcal {B}(\mu \rightarrow e \gamma )$$ B ( μ → e γ ) , which is at most $$10^{-21}-10^{-20}$$ 10 - 21 - 10 - 20 . …”
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Identification of Target Genes of Antiarrhythmic Traditional Chinese Medicine Wenxin Keli by Yusi Yao, Yuhong Liu, Zhihuan Zeng, Yanqun Zhao, Tudi Li, Rong Chen, Rendan Zhang

“…In addition, the expression of sodium channel protein type 5 subunit alpha (SCN5A) and beta-2 adrenergic receptor (ADRB2) was downregulated, while muscarinic acetylcholine receptor M2 (CHRM2) was upregulated in the WXKL group (P<0.05). …”
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Romanian validation study of the Boston questionare in patients with carpal tunnel syndrome by Lenuța Bîrsanu, Roxana Covali, Emanuel Matei Roman, Ioan Alexandru Chirap-Mitulschi, Alin Ciubotaru, Mihaela-Dana Turliuc

“…Our results showed a very good construct validity and excellent reliability (Cronbach's alpha = 0.79) for Boston Carpal Tunnel Questionnaire -Romanian version and the Kaiser-Meyer-Olkin of 0.732, which is considered acceptable (a value above 0.70 is usually statistically significant for factor analysis). …”
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