Characterization of the Merkel Cell Carcinoma miRNome by Matthew S. Ning, Annette S. Kim, Nripesh Prasad, Shawn E. Levy, Huiqiu Zhang, Thomas Andl

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Rare Site of an Inflammatory Myofibroblastic Tumor at the Epididymis: A Case Report by Lange A, Dominiak N, Petros FG

“…Tumor markers were unremarkable for lactate dehydrogenase (LDH), beta-human chorionic gonadotropin (b-hCG), and alpha-fetoprotein (AFP). A right inguinal approach was performed. …”
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Health Literacy Influences Heart Failure Knowledge Attainment but Not Self-Efficacy for Self-Care or Adherence to Self-Care over Time by Aleda M. H. Chen, Karen S. Yehle, Nancy M. Albert, Kenneth F. Ferraro, Holly L. Mason, Matthew M. Murawski, Kimberly S. Plake

“…Repeated measures analysis of variance with Bonferroni-adjusted alpha levels was used to test longitudinal outcomes. …”
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Cells and Cytokines in Milk of Subclinically Infected Bovine Mammary Glands after the Use of Immunomodulatory Composition GLP 810 by Gundega Gulbe, Māra Pilmane, Vaira Saulīte, Simona Doniņa, Jevgenijs Jermolajevs, Lilija Peškova, Anda Valdovska

“…The analyses of tumour necrosis factor-alpha, interleukin-10, and beta-defensin-2 revealed that the production of the aforementioned cytokines significantly increased, whereas no significant effects on interleukin-1 and caspase-6 expression in milk leukocytes were recorded. …”
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Ghrelin Protects Lipopolysaccharide-Induced Acute Lung Injury Rats against Pulmonary Vascular Dysfunction by Inhibiting Inflammation by Guang Li, Chen-Liang Zhou, Wen-Fang Xia, Di Zhang, Hui-Qing Lin

“…Immunohistochemical staining to detect alpha-smooth muscle actin (α-SMA) and proliferating cell nuclear antigen (PCNA) expression was performed to assess the intrapulmonary arterial wall thickness and the proliferation of smooth muscle cells, respectively. …”
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Structural analysis of the impact of learning from errors and organizational failures on innovative performance with the mediation role of knowledge absorptive capacity (case study... by Sara Mohammadi, Farajallah Rahimi, Eslam Fakher, Ilnaz Irani Behbahani

“…The validity and reliability of these questionnaires were confirmed using content validity and Cronbach's alpha (above 0.7).Findings: The results of the structural equation modeling test using SmartPLS-3 software indicated that although learning from organizational errors has a direct and significant impact on innovative performance, it also leads to a greater increase in innovative performance through employees' absorptive capacity. …”
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Inhibitory Effect of Flavonoid Extract of Lotus Leaf on Alcohol-Induced Gastric Injury by Antioxidant Capacity in Mice by Yi Chen, Qin Li, Zhiping Kuang, Xin Zhao, Ruokun Yi, Xiaowei He, Guangjing Feng

“…Besides, FELL significantly reduced the levels of interleukin 6 (IL-6), interleukin 12 (IL-12), tumor necrosis factor alpha (TNF-α), and interferon gamma (IFN-γ). The quantitative polymerase chain reaction (qPCR) and Western blot results proved that FELL upregulated the mRNA and protein expressions of SOD1, SOD2, CAT, epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), neuronal nitric oxide synthase (nNOS), and endothelial nitric oxide synthase (eNOS) and downregulated the expression of inducible nitric oxide synthase (iNOS) in the gastric tissue of mice with gastric injury. …”
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Corporate genome screening India (CoGsI) identified genetic variants association with T2D in young Indian professionals by Shah Fahad Husami, Tavleen Kaur, Love Gupta, Garima Rastogi, Lakhvinder Singh, Pooja Meena, Indu Sharma, Hemender Singh, Varun Sharma

“…Out of 42, three missense variants (rs1402467, rs6050, and rs713598) in Sulfotransferase family 1 C member 4 (SULT1C4), Fibrinogen Alpha Chain (FGA), and Taste 2 Receptor Member 38 (TAS2R38) and two untranslated region (UTR) variants (rs1063320 and rs6296) in Major Histocompatibility Complex, Class I, G (HLA-G) and 5-Hydroxytryptamine Receptor 1B (HTR1B) were associated with the T2D risk. …”
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6-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPARδ in HUVECs, HEK293, and Differentiated 3T3-L1 Cells by Yong-Jik Lee, Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, Hong Seog Seo

“…The lipid accumulation in differentiated 3T3-L1 cells was evaluated by using Oil Red O staining. 6- Gingerol increased the level of phosphorylated endothelial nitric oxide synthase (eNOS) protein but decreased that of vascular cell adhesion protein 1 (VCAM1) and tumor necrosis factor alpha (TNFα) in HUVECs. In HEK293 cells, the expression of the epithelial sodium channel (ENaC) protein was reduced by 6-gingerol. …”
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NHSL3 controls single and collective cell migration through two distinct mechanisms by Nikita M. Novikov, Jinmei Gao, Artem I. Fokin, Nathalie Rocques, Giovanni Chiappetta, Karina D. Rysenkova, Diego Javier Zea, Anna Polesskaya, Joelle Vinh, Raphael Guerois, Alexis M. Gautreau

“…We identify the partner repertoire of each isoform using proteomics and predict direct partners and their binding sites using an AlphaFold2-based pipeline. Rescue with specific isoforms, and lack of rescue when relevant binding sites are mutated, establish that the interaction of a long isoform with MENA/VASP proteins is critical at cell-cell junctions for collective migration, while the interaction of a short one with 14-3-3θ in lamellipodia is critical for single cell migration. …”
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Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice by Hongxing Zhang, Chi Shang, Zhao Tian, Hatem K. Amin, Rami B. Kassab, Ahmed E. Abdel Moneim, Yingang Zhang

“…Carrageenan injection potentiated an inflammatory reaction as presented by the elevated serological C-reactive protein (CRP) levels and transcription of tumor necrosis factor-alpha (TNF-α, Tnfα), interleukin-1 beta (IL-1β, Il1b), interleukin-2 (IL-2, Il2), inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase-2 (COX-2, Ptgs2), prostaglandin E2 (PGE2), monocyte chemoattractant protein-1 (MCP-1, Ccl1), nuclear factor kappa B (NF-κB), and myeloperoxidase (MPO) activity, while interleukin-10 (IL-10) was declined in the injured paw tissue. …”
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Reduced Systemic Levels of IL-10 Are Associated with the Severity of Obstructive Sleep Apnea and Insulin Resistance in Morbidly Obese Humans by Sonia Leon-Cabrera, Yoaly Arana-Lechuga, Enrique Esqueda-León, Guadalupe Terán-Pérez, Antonio Gonzalez-Chavez, Galileo Escobedo, Javier Velázquez Moctezuma

“…Blood samples were obtained for estimation of total cholesterol and triglycerides, insulin, glucose, insulin resistance, tumor necrosis factor alpha (TNF-α), interleukin 12 (IL12), and interleukin 10 (IL-10). …”
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Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based in silico approaches by David Hoffmann, Joschka Bauer, Markus Kossner, Andrew Henry, Anne R. Karow-Zwick, Giuseppe Licari

“…The most effective QSAR model considered the accessible surface area (ASA) of the residue, the pKa value of the backbone amide, and the root mean square deviations of both the alpha carbon and the side chain. The accuracy was further enhanced by incorporating the QSAR model into a decision tree, which also includes empirical information about the sequential successor and the position in the protein. …”
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Using selective NIR wavelengths in portable devices to evaluate the chemical composition of cattle feeds by Lorenzo Serva, Luisa Magrin, Giovanni Chillemi, Giorgio Marchesini, Daniele Pietrucci, Francesco Renzi, Riccardo Valentini, Igino Andrighetto, Marco Milanesi

“…External validation was accomplished with spectra collected by different instruments, origins and sample types, and the highest adjusted coefficients of determination in validation were 0.95 for dry matter and 0.84 for alpha-amylase and sodium sulphite-treated NDF. Results demonstrated that using a few spectral bands is suitable for instrument calibration.…”
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Potential Candidate Genes Associated with Litter Size in Goats: A Review by Wenting Chen, Ying Han, Yinghui Chen, Xiaotong Liu, Huili Liang, Changfa Wang, Muhammad Zahoor Khan

“…Recent advancements in genetic research have identified key genes and pathways associated with reproductive traits, including gonadotropin-releasing hormone (<i>GnRH</i>), inhibin (<i>INHAA</i>), Kit ligand (<i>KITLG</i>), protein phosphatase 3 catalytic subunit alpha (<i>PPP3CA</i>), prolactin receptor (<i>PRLR</i>), POU domain class 1 transcription factor 1 (<i>POU1F1</i>), anti-Müllerian hormone (<i>AMH</i>), bone morphogenetic proteins (<i>BMP</i>), growth differentiation factor 9 (<i>GDF9</i>), and <i>KISS1</i> and suppressor of mothers against decapentaplegic (<i>SMAD</i>) family genes, among others. …”
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Challenges and future prospects of online practical education in physical education faculties during the COVID-19 pandemic by O.M. Abdel Fattah, A.A. Zureigat, S.H. Qasim, M.A. Alzughailat, A.S. Khasawneh

“…We used frequencies, percentages, Cronbach’s alpha coefficient, mean, standard deviations, three-way ANOVA, and Scheffe test to address the study sample responses.Results. …”
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Predicting Factors Affecting the Behavior of Healthcare Employees in the Use of Personal Protective Equipment During Epidemics Based on Godin et al’s Model: A Study in Iran by Milad Ahmadi Marzaleh, Peivand Bastani, Abolfazl Raeyat Mohtashami, Payam Farhadi, Saeed Ghanbari, Ramin Ravangard

“…After reviewing the related articles and interviewing the experts and based on the model of Godin et al. (2008), a questionnaire was developed, validated, and tested for reliability using face and content validity as well as Cronbach’s alpha. Collected data were analyzed using SPSS v.21 and modeled by Structural Equation Modeling (SEM) via SPSS v.21 and Smart PLS v.3 software. …”
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Muhâsebede Hata ve Hilelerin Önlenmesinde Mali Hizmet Çalışanlarının Sorumluluğunun Tespitine Yönelik Bir Araştırma by Onur Açıkgöz, Enis Baha Biçer

“…Araştırmanın Croanbach Alpha değeri 0,72 olarak hesaplanmıştır. Anket soruları demografik bilgiler, muhasebe hataları, muhasebe hileleri ve mali hizmet çalışanlarının sorumlulukları olmak üzere 4 bölümden oluşmaktadır. …”
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C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability by Santhosh Kumar Nagarajan, Joy Weber, Daniel Roderer, Jörg Piontek

“…While the mechanism of CPE-claudin interaction is well understood, the structure and assembly of the pore complex remain elusive. Here, we used AlphaFold2 complex prediction, structure alignment, and molecular dynamics simulations to generate models of prepore and pore states of the CPE/claudin-4 complex. …”
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Translation, cross-cultural adaptation and validation of the composite physical function scale in Chinese community-dwelling older adults by Jiaying Qi, Jing Xu, Hui Zhang, Mingshuai Feng, Hongyan Meng, Li Wang

“…Results The C-CPF was consistent with the original version, which consisted of a single dimension with 12 items. It had a Cronbach’s alpha coefficient of 0.901, fold-half reliability of 0.831 and test–retest reliability of 0.994. …”
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