Evaluating the resilience of the drug supply chain based on SWARA and CoCoSo multi criteria decision making approach with type 1 and interval type 2 fuzzy data (case study: Bojnord... by Fatemeh Bahman, Alireza Shahraki, Sayyid Ali Banihashemi

“…The questionnaire was approved by experts, and its reliability with Cronbach's alpha coefficient of 0.965. The percentage of personal characteristics was calculated using SPSS-26 software. …”
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INVESTIGATING THE BIOCHEMICAL PROFILE AND NUTRITIONAL COMPOSITION OF VERNONIA AMYGDALINA LEAVES: A STUDY ON ANTIOXIDANT PROPERTIES, PHYTOCHEMICAL COMPOSITION, ENZYME INHIBITION, AN... by Olugbenga D. Oloruntola, Fehintoluwa S. Oladebeye, Samuel A. Adeyeye, Simeon O. Ayodele, Ojurereoluwa A. Ayodele, Olufemi E. Adeniji

“…Moreover, the study unveiled the extract’s inhibitory effects on key enzymes and proteins involved in metabolic processes, with notable rates of 29.34% for anti-glucosidase activity, 43.28% for alpha-amylase inhibition, 34.44% for albumin denaturation inhibition, and 57.04% for anti-proteinase activity. …”
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Xylazine as a Drug of Abuse and Its Effects on the Generation of Reactive Species and DNA Damage on Human Umbilical Vein Endothelial Cells by Luz Silva-Torres, Christian Veléz, Lyvia Álvarez, Beatriz Zayas

“…Human xylazine (XYL) abuse among addicts has received great interest due to its potential toxic effects upon addicts and the need to understand the mechanism of action associated with the potential health effects. XYL is an alpha-2 agonist restricted to veterinarian applications, without human medical applications. …”
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The highly prolific phenotype of Lacaune sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary. by Laurence Drouilhet, Camille Mansanet, Julien Sarry, Kamila Tabet, Philippe Bardou, Florent Woloszyn, Jérome Lluch, Grégoire Harichaux, Catherine Viguié, Danielle Monniaux, Loys Bodin, Philippe Mulsant, Stéphane Fabre

“…The identification of these glycoproteins by mass spectrometry revealed at least 10 proteins, including inhibin alpha and betaA subunits, as potential targets of B4GALNT2 activity. …”
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Two Cases of Severe Hypertension in JAK2 Mutation-Positive Myeloproliferative Neoplasms by Raunak Rao, Spoorthy Kulkarni, Ian B. Wilkinson

“…Aspirin, long-acting nifedipine, interferon-alpha 2A, and renal artery angioplasty were employed in management. …”
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NDUFA11 may be the disulfidptosis-related biomarker of ischemic stroke based on integrated bioinformatics, clinical samples, and experimental analyses by Sijun Li, Ningyuan Chen, Junrui He, Xibao Luo, Wei Lin

“…Based on IS models, experimental analyses were performed to verify DE-DRB expression and the correlation between DE-DRBs.ResultsLeucine-rich pentatricopeptide repeat-containing (LRPPRC) and NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (NDUFA11) were identified as DE-DRBs. …”
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Concepciones acerca del aprendizaje: diseño y validación de un cuestionario para profesores en formación by Silvia L. Vilanova, María B. García, Orlanda Señoriño

“…Para determinar la fiabilidad del análisis factorial y en consecuencia, la validez de constructo, se utilizó el Alpha de Cronbach. El posterior análisis de los datos muestra el uso de la teoría interpretativa del aprendizaje, basada en una concepción epistemológica vinculada con el realismo crítico.…”
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A New Functional Model for Prediction of Chaperone Activity of the Recombinant M. tb Acr (α-Crystallin) Using Insulin as Substrate by Gautam Krishnan, Utpal Roy

“…In this study, Mycobacterium alpha crystallin (acr) gene was cloned and expressed in Escherichia coli (E. coli). …”
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Elevated Serum TNF-α Is Related to Obesity in Type 2 Diabetes Mellitus and Is Associated with Glycemic Control and Insulin Resistance by Hana Alzamil

“…Tumor necrosis factor alpha (TNF-α) is a cytokine that is released by adipocytes and inflammatory cells in response to chronic inflammation. …”
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Wharton’s Jelly Mesenchymal Stem Cell Conditioned Medium Ameliorates Diabetes-Induced Testicular Damage and Sperm Abnormalities by Mitigating Oxidative Stress, Apoptosis, and Infla... by Mojtaba Sargazi, Narges Karbalaei, Saied Karbalay-Doust, Sara Keshtgar, Zohre Aghaei

“…Real-time PCR detected Bax, Bcl-2, and tumor necrosis factor-alpha (TNF-α) gene expression. Our results showed that diabetes increased blood glucose levels, decreased insulin and sex hormone levels, induced testicular oxidative stress and apoptosis, and reduced sperm parameters compared to the control. …”
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The Fatty Acid Profile in Patients with Newly Diagnosed Diabetes: Why It Could Be Unsuspected by C. Castro-Correia, S. Sousa, S. Norberto, C. Matos, V. F. Domingues, M. Fontoura, C. Calhau

“…Our findings showed higher levels of alpha-linolenic acid, EPA, and DHA, as well as mono- and polyunsaturated fatty acids, in diabetic children. …”
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Turkish validity and reliability of Burnout Syndrome Assessment Scale for nurses working in intensive care units by Yağmur Dağ, Gülsün Özdemir Aydın, Nuray Turan

“…Internal consistency analyses were conducted using Cronbach’s alpha coefficients and item analysis. Confirmatory factor analysis was employed to evaluate the construct validity. …”
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The Impact of Digital Challenges On the Development of Startups In the Tourism Sector In Algeria by Narimane Benabderrahmane

“…And quantitative research was conducted by preparing a questionnaire to measure determinants of digital transformation and challenges directed towards owners of startups providing various tourism services, The result of Cronbach's alpha is 0.795 that indicates that the internal reliability of this set is acceptable. …”
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Oxidative stress and inflammation in hemodialysis: a comparison of patients with or without advanced nonalcoholic fatty liver disease (NAFLD) by Vanja Kalacun, Robert Ekart, Sebastjan Bevc, Pavel Skok, Radovan Hojs, Nina Vodošek Hojs

“…HD patients with advanced NAFLD had significantly higher levels of 8-hydroxy-2’-deoxyguanosine (8-OHdG; p = 0.025), tumor necrosis factor-alpha (TNF-α; p = 0.023), and intercellular adhesion molecule 1 (ICAM-1; p = 0.015) in comparison to HD patients without advanced NAFLD. …”
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Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis by Azael Torales-Cardeña, Isaí Martínez-Torres, Sandra Rodríguez-Martínez, Fernando Gómez-Chávez, Juan C. Cancino-Díaz, Ernesto A. Vázquez-Sánchez, Mario E. Cancino-Díaz

“…Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor “hypoxia-inducible factor 1-alpha” (HIF-1α) is involved in the homeostasis of these three biological phenomena. …”
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Changes of Immunological Profiles in Patients with Chronic Myeloid Leukemia in the Course of Treatment by Zuzana Humlová, Hana Klamová, Ivana Janatková, Karin Malícková, Petra Králíková, Ivan Šterzl, Zdeněk Roth, Eva Hamšíková, Vladimír Vonka

“…After treatment with hydroxyurea, interferon alpha, imatinib mesylate and dasatinib, or various combinations thereof, hematological remission was achieved in all patients and complete cytogenetic remission in nine of them. …”
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Re-presentations to the emergency department initial presentation with COVID-19: Insights from the omicron wave by Daniella Audish, George Braitberg, Anselm Wong

“…Conclusion: Re-presentation rates were similar to previous COVID waves with the alpha and delta variants. Respiratory symptoms and related diagnoses were common. …”
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Antimicrobial Peptides from Porcine Blood Cruor Hydrolysates as a Promising Source of Antifungal Activity by Sara García-Vela, Aurore Cournoyer, Zain Sánchez-Reinoso, Laurent Bazinet

“…Five new peptide sequences demonstrated antifungal activity, with Pep5 (FQKVVAGVANALAHKYH), an alpha-helix peptide, exhibiting the most promising results. …”
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Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene by Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu

“…Hepatic relative expressions of tumour necrosis factor-alpha (TNF-α), interleukin-six (IL-6), and nuclear factor-erythroid 2 related factor 2 (Nrf-2) were also assessed. …”
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High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels by Fangjun Chen, Priscilla S.-W. Yeung, Carolyn V. Wong, Ruben Y. Luo

“…Methods: Apparent CarHb/Hb ratios were calculated from the peak area ratios of carbamylated to native N-terminal peptides digested from hemoglobin alpha and beta subunits. Blood samples from healthy individuals, CKD patients, and chronic obstructive pulmonary disease (COPD) patients were analyzed. …”
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