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2021
Evaluation of the Desire to Avoid Pregnancy Scale in the UK: a psychometric analysis including predictive validity
Published 2022-07-01“…Objectives To evaluate the psychometric performance, including predictive validity, of a UK version of the Desire to Avoid Pregnancy (DAP) scale.Design Prospective cohort study for psychometric evaluation.Setting UK.Participants Women in the UK aged 15 years to menopause, who were not pregnant at the time of recruitment in October 2018, were eligible. 994 women completed the baseline survey and 90.2% of women eligible for the 12-month survey participated.Primary and secondary outcome measures The DAP scale was assessed according to key measurement properties of validity (construct (structural and hypothesis testing) and criterion (predictive)), reliability (internal consistency using Cronbach’s alpha and test–retest using intraclass correlation coefficients, ICC) and differential item functioning. …”
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2022
Analysis and Characterization of the Immunogenicity of Rhoptry Protein 18
Published 2025-02-01“…The secondary structure was composed of 4.87% beta-turns, 38.45% random coils, 42.42% alpha helices, and 14.26% extended strands. Several potential T- and B-cell epitopes were identified on ROP18. …”
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2023
Development of Cutaneous Leishmaniasis after Leishmania Skin Test
Published 2011-01-01“…Mononuclear cells harvested from the patient were stimulated with Leishmania antigen and showed high levels of production of both tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ): 2,943 pg/mL and 2,313 pg/mL, respectively. …”
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2024
Accuracy of Teledentistry for Diagnosis and Treatment Planning of Pediatric Patients during COVID-19 Pandemic
Published 2022-01-01“…Interexaminer reliability was measured using the intraclass correlation coefficient (ICC) and Cronbach’s alpha. The mean kappa coefficient for the interexaminer agreement (for 24 teeth) was 0.62 in clinical and 0.69 in virtual examinations. …”
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2025
Does quercetin affect tendon healing? An experimental study in a rat model of Achilles tendon injury
Published 2025-02-01“…In the immunohistochemical analysis, type I collagen, type III collagen, alpha smooth muscle actin (SMA), and Galectin-3 were evaluated, and it was observed that quercetin increased tendon healing (p-values = 0.0166, 0.0036, 0.0323, 0.0295, respectively). …”
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2026
Melanocortin Peptide Therapy for the Treatment of Arthritic Pathologies
Published 2009-01-01“…Here we discuss the role of naturally occurring pro-opiomelanocortin (POMC)-derived melanocortin peptides (e.g., alpha melanocyte stimulating hormone [a-MSH]) and synthetic derivatives in these diseases. …”
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2027
Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma
Published 2014-01-01“…VHL is part of the VHL elongin BC protein complex that also includes CUL2/5, TCEB1, TCEB2, and RBX1; in normoxic conditions this complex targets hypoxia-inducible factor 1 alpha (HIF1A) for degradation, thus preventing a hypoxic response. …”
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2028
Association of Major Histocompatibility Complex Polymorphism With Acute Phase Response in Broiler Chicken
Published 2024-11-01“…In addition, acute phase proteins (APPs), including serum amyloid A (SAA) and alpha‐1‐acid glycoprotein (AGP), were analysed as markers of the APR. …”
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2029
Chromosome Numbers and Reproductive Life Cycles in Green Plants: A Phylotranscriptomic Perspective
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2030
Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma
Published 2021-01-01“…Liver tissues from 15 patients with HCC were collected and the levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), IL-1α, IL-1 β, IL-10, and transforming growth factor-beta1 (TGF-β1) were assessed using real-time PCR assay at different times before and after LR. …”
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2031
Cerebrospinal fluid metabolites as potential biomarkers for epilepsy: Insights from genome‐wide association studies
Published 2025-02-01“…After False Discovery Rate (FDR) multiple testing correction, two metabolites (Methylmalonate and Gamma‐glutamyl‐alpha‐lysine) were found to have robust causal links to epilepsy (p < 0.05 and FDR<0.05). …”
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2032
Gastric Microbiota Associated with Gastric Precancerous Lesions in <i>Helicobacter pylori</i>-Negative Patients
Published 2025-01-01“…No significant difference was observed in the alpha or beta diversity of the gastric microbiota among the groups. …”
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2033
The Mediating Role of Human Resources and Internal Processes on the Relationship between Innovation Strategy and Financial Performance
Published 2023-02-01“…The study's statistical population consists of financial managers and senior accounting supervisors of production units in Yazd province; simple random sampling was used to select the sample, and 100 acceptable questionnaires were collected and analyzed. Cronbach's alpha coefficient confirmed the content validity of the questionnaires according to experts' opinions, and the reliability was confirmed using confirmatory factor analysis. …”
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2034
Forsythia suspensa leaf fermented tea extracts attenuated oxidative stress in mice via the Ref-1/HIF-1α signal pathway and modulation of gut microbiota
Published 2025-02-01“…FSLFT has been shown to have antioxidant effects via the Redox Factor-1(Ref-1)/ hypoxia-inducible factor-1 alpha (HIF-1α) pathway, reduce inflammation caused by hydrogen peroxide through the Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) signaling pathway, and protect mouse colons from oxidative stress by repairing gut microbiota imbalance and increasing microbial diversity and abundance. …”
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2035
Association between fluoride exposure and the risk of serum CK and CK-MB elevation in adults: a cross-sectional study in China
Published 2025-01-01“…This study found that there was a positive association between urinary fluoride concentration and the risk of CK-MB elevation in participants under the age of 60 years(OR = 2.18 [95% CI: 1.39–3.42]), those who were of female gender (OR = 1.53 [95% CI: 1.07–2.19]), those who were overweight/obese (OR = 1.96 [95% CI: 1.28–2.99]), those who had central obesity (OR = 1.59 [95% CI: 1.12–2.25]), consumed alcohol (OR = 1.49 [95% CI: 1.09–2.05]), and smoked (OR = 1.50 [95% CI: 1.10–2.04]).ConclusionOur study suggests that fluoride exposure is associated with the risk of serum CK and CK-MB elevation; however, it is not associated with myocardial ischemia, arrhythmia, serum lactate dehydrogenase (LDH), serum alpha-hydroxybutyrate dehydrogenase (α-HBD), or serum aspartate aminotransferase (AST). …”
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2036
Pathological characterization of lung fibrosis in Sprague–Dawley rats treated with fluoro-edenite fibres by intrapleural injection
Published 2024-12-01“…In the fibrotic responses to FE, vimentin was the most expressed protein, followed by collagen-I and alpha-SMA. Finally, ferruginous bodies, characterized by iron deposits and ferritin expression, were observed in FE-induced lesions. …”
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2037
Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women
Published 2025-02-01“…At the genus level, the relative abundance of Lactobacillus in the Con group was 2.2 times higher than that in the OwOb group. The Alpha diversity in the OwOb group was significantly higher than in the Con group (p=0.028). …”
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2038
Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
Published 2023-09-01“…Platelet factor 4 variant (PF4V1), Pregnancy-specific beta-1-glycoprotein 2 (PSG2), Profilin-1 (PFN1) and Keratin type II cytoskeletal 2 epidermal (KRT2) showed decreased expressions, while Integrin alpha-IIb (ITGA2B) showed an increased expression after treatment with rosuvastatin. …”
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2039
Plant-Derived Compounds in Hemp Seeds (<i>Cannabis sativa</i> L.): Extraction, Identification and Bioactivity—A Review
Published 2024-12-01“…In addition to the content of proteins and healthy fats (linoleic acid and alpha-linolenic acid), hemp seeds are rich in phytochemical compounds, especially terpenoids, polyphenols, and phytosterols, which contribute to their bioactive properties. …”
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2040
Antifungal Efficacy of Ganoderma lucidum and Clotrimazole for Treatment of Denture Stomatitis: A Randomized Clinical Trial
Published 2024-12-01“…Data were analyzed using the Chi-square test, independent samples t-test, repeated measures ANOVA, and logistic regression (alpha=0.05). Results: The percentage of complete recovery on day 7 in the G. lucidum group (28%) was higher than that in the clotrimazole group (16%) but not significantly (P=0.592). …”
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