Regulating the PI3K and AMPK pathway: the secret of 1-deoxynojirimycin's success in alleviating chronic diseases by Chengwei Yu, Qirui Hu

“…The 1-deoxynojirimycin (DNJ) is the unique alkaloid and the primary component for hypoglycemic effects in the mulberry leaves. …”
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Pemanfaatan Limbah Puntung Rokok sebagai Inhibitor Korosi pada Baja St40 Menggunakan Metode Microwave Assisted Extraction (MAE) di Lingkungan NaCl 3,56% by Ikhsan Akmal Alatif, Rahma Puspa Permatasari, Rahma Nurulgina, Zahrotul Filza Adzkia, Puri Andayani, Sabrina Aisyah Putri, Adinda, Dhyna Analyes Trirahayu, Kunlestiowati Hadiningrum

“…Based on the GC-MS test, it is known that cigarette butts waste extract contains alkaloid, terpenoid, and phenol compounds as corrosion inhibitor compounds. …”
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Phytochemical Profiles and Antioxidant and Antimicrobial Activities of the Leaves of Zanthoxylum bungeanum by Yujuan Zhang, Ziwen Luo, Dongmei Wang, Fengyuan He, Dengwu Li

“…The ethyl acetate fraction (EAF) had the highest total phenolic (97.29 mmol GAE/100 g) and flavonoid content (67.93 mmol QE/100 g), while the greatest total alkaloid content (4.39 mmol GAE/100 g) was observed in the chloroform fraction (CF). …”
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Study on Antibacterial Activities of Croton macrostachyus and Pycnostachys abyssinica Leaf Extracts Against Some Human Pathogens by Getahun Yemata, Endalamaw Yihune, Yewulsew Kebede

“…The phytochemical screening showed more abundant phenolic compounds and tannins in the extract of C. macrostachyus and alkaloid, flavonoid, phenolic compounds, and tannins in the extract of P. abyssinica. …”
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Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins by Pavić Kristina, Poje Goran, Carvalho Lais Pessanha De, Held Jana, Rajić Zrinka

“…Here we present the synthesis and evaluation of the biological activity of new hybrid compounds, ureido-type (UT) harmiquins, based on chloroquine (CQ) or mefloquine (MQ) scaffolds and β-carboline alkaloid harmine against cancer cell lines and Plasmodium falciparum. …”
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Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Yizhuo Wang, Kunjian Liu, Zhiyong Qi, Tong Chen, Wei Yu, Yang Jiang, Guofeng Li, Huijie Xiao

“…Camptothecin (CPT) is a cytotoxic quinoline alkaloid isolated from the bark and branches of the Chinese tree Camptotheca acuminata. …”
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Modulation of Tyrosine Hydroxylase, Neuropeptide Y, Glutamate, and Substance P in Ganglia and Brain Areas Involved in Cardiovascular Control after Chronic Exposure to Nicotine by Merari F. R. Ferrari, Emerson F. Coelho, Karen L. G. Farizatto, Gerson Chadi, Debora R. Fior-Chadi

“…Immunohistochemical and in situ hybridization data demonstrated increased expression of TH in brain and ganglia related to blood pressure control, preferentially in SHR, after nicotine exposure. The alkaloid also increased NPY immunoreactivity in ganglia, NTS, and PVN of SHR, in spite of decreasing its receptor (NPY1R) binding in NTS of both strains. …”
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Optimizing Extraction, Evaluating Antioxidant Activity, and Analyzing Bioactive Compounds in Trikaysornmas Formula by Suphatson Limsakul, Orawan Monthakantirat, Yaowared Chulikhit, Juthamart Maneenet, Charinya Khamphukdee, Yutthana Chotritthirong, Achiraya Phasomsap, Chantana Boonyarat, Supawadee Daodee

“…Phytochemical components such as total phenolics, total flavonoids, total carotenoids, and total alkaloids were assessed utilizing a colorimetric method. …”
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Evaluation of Tinospora cordifolia stem extract bioactive content and anticancer activity against breast cancer cells by Annisa Yuslinda, Rosyadah Nuraini, Kamila Fairuz Sarah, Ulfa Siti Mariyah, Lestari Sri Rahayu, Widodo Nashi

“…This study aims to explore the bioactive potential of Tinospora cordifolia stem extract by investigating the content of flavonoids, phenols, terpenoids and alkaloids as well as the cytotoxic and apoptotic effects on T47D breast cancer cells. …”
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Bioinsecticide Production from Cigarette Wastes by Badhane Gudeta, Solomon K, M. Venkata Ratnam

“…Nicotine, the primary component of tobacco products such as cigarettes, is an alkaloid and can be used as an insecticide. This research aims to extract nicotine from discarded cigarette butts and utilize it as an insecticide. …”
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Efek Ekstrak Etanol Daun Kesum (Polygonum minus Huds.) sebagai Antifungi terhadap Trichophyton rubrum by Shintya Dewi, Syarifah NYRS Asseggaf, Diana Natalia, Mahyarudin Mahyarudin

“…Hasil penelitian pada skrining fitokimia didapatkan flavonoid, saponin, alkaloid, terpenoid, dan fenol. Ekstrak etanol daun kesum memiliki aktivitas antifungi pada konsentrasi 5%; 10%; 20%; 40%; 80%. …”
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Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats by Juan Chen, Anjing Lu, Daopeng Tan, Qianru Zhang, Yanliu Lu, Lin Qin, Yuqi He

“…Scopolamine, as a tropane alkaloid found in plants such as belladonna and datura, is used clinically as a transdermal patch and is highly neurotoxic. …”
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Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease by Dmitri Leonoudakis, Anand Rane, Suzanne Angeli, Gordon J. Lithgow, Julie K. Andersen, Shankar J. Chinta

“…Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, has been reported to have potent biological activity and is used in the treatment of neurological conditions such as amyotrophic lateral sclerosis, poliomyelitis, and multiple sclerosis. …”
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Forensic classification of narcotic drugs by R. L. Stepaniuk, S. M. Lozova

“…In these groups, it is important to use generic names that describe the source of the drug, systematising natural and semi-synthetic drugs depending on the natural source of the main substance (alkaloid), and synthetic drugs – on the corresponding chemical compound. …”
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In Vitro Experimental Assessment of Ethanolic Extract of Moringa oleifera Leaves as an α-Amylase and α-Lipase Inhibitor by Adebanke Ogundipe, Babatunde Adetuyi, Franklyn Iheagwam, Keleko Adefoyeke, Joseph Olugbuyiro, Oluseyi Ogunlana, Olubanke Ogunlana

“…The result of the phytochemical screening revealed the presence of total phenolic, flavonoid, tannin, and alkaloid contents of values 0.070 ± 0.005 mg gallic acid equivalent/g, 0.180 ± 0.020 mg rutin equivalent/g, 0.042 ± 0.001 mg tannic equivalent/g, and 12.17 ± 0.001%, respectively, while the total protein analysis was 0.475 ± 0.001 mg bovine serum albumin equivalent/g. …”
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Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo by Sura Akram, Ahmed Majeed Al-Shammari, Hayder B. Sahib, Majid Sakhi Jabir

“…Therefore, we aimed at assessing the novel combination of the AMHA1 strain of Newcastle disease virus (NDV) and nonnarcotic opium alkaloid (papaverine) against breast cancer models in vitro and in vivo. …”
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Pengaruh Pemberian Air Rendaman Rumput Fatimah (Anastatica Hierochuntica) Terhadap Kadar Hormon Oksitosin dan Hormon Prolaktin Pada Tikus Putih (Rattus Norvegicus) Menyusui Perband... by Yunni Safitri, Afriwardi Afriwardi, Eny Yantri

“…Rumput fatimah (Anastatica Hierochuntica) mengandung senyawa fitokimia seperti alkaloid, tanin, dan flavonoid yang merupakan bagian fitoestrogen. …”
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Antifungal Activity and Major Bioactive Compounds of Water Extract of Pangium edule Seed against Aspergillus flavus by Kharisma I. Listyorini, Harsi D. Kusumaningrum, Hanifah N. Lioe

“…The water extract was compared to the extracts obtained by multilevel maceration using 50% ethanol, ethyl acetate, and n-hexane as solvents. Alkaloid, saponin, phenolic compound, flavonoid, triterpenoid, and glycoside were detected qualitatively in the crude extracts. …”
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Biochemical and toxicological evaluation of Solanum viarum fruit extract on Dugesia tigrina by Schaly Felipe, Braguini Welligton Luciano

“…Solanum viarum has alkaloid-rich fruits. We evaluated the antioxidant and chelating activities of the aqueous extract fraction (AEF) from S. viarum fruits and its effects on the brown planarian Dugesia tigrina. …”
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Nutritional Indices, Phytochemistry, and the In Vitro Antioxidant Activity of Carrot Fortified Tomato Concentrate by Olabisi Theresa Ademosun, Abiodun Humphrey Adebayo, Kolawole Oluseyi Ajanaku

“…Phytochemical screening showed the presence of terpenoids, cardiac glycosides, saponins, phenols, flavonoids, and alkaloids in the studied formulations. Furthermore, the incorporation of carrot led to an increase in TPC, TFC, and alkaloid concentration. …”
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