Bioactive Phytochemicals: Bioactivity, Sources, Preparations, and/or Modifications via Silver Tetrafluoroborate Mediation by Matthew C. Achilonu, Dennis O. Umesiobi

“…This review provides an overview of the biological activities, natural occurrences, and the silver tetrafluoroborate- (AgBF4-) mediated synthesis of proanthocyanidins, glycosides, N-heterocyclic alkaloid analogues (of pyrrole, morphine, quinoline, isoquinoline, and indole), furan analogues, and halocompounds. …”
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Spectrophotometric Analysis of Caffeine by Showkat Ahmad Bhawani, Sim Siong Fong, Mohamad Nasir Mohamad Ibrahim

“…The nature of caffeine reveals that it is a bitter white crystalline alkaloid. It is a common ingredient in a variety of drinks (soft and energy drinks) and is also used in combination with various medicines. …”
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EFEKTIVITAS EKSTRAK ETANOL DAUN MAHONI (Swietenia mahagoni (L.) Jacq.) TERHADAP LARVA Aedes aegypti L. by Tisa Rizkika Nur Amelia

“…The result indicated that ethanolic extract of S. mahagoni leaf contained alkaloid, tannin, saponin, terpenoid, and flavonoid compounds. …”
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Effect of colchicine on physiological and biochemical properties of <i>Rhodococcus qingshengii</i> by Yu. A. Markova, L. A. Belovezhets, V. N. Nurminsky, I. S. Kapustina, N. V. Ozolina, V. V. Gurina, A. L. Rakevich, A. V. Sidorov

“…To understand the mechanism of action of this alkaloid on the bacterial cell, we have studied the change in the fatty acid composition and microviscosity of the R. qingshengii VKM Ac-2784D membrane. …”
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Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease by Hong-Fang Ji, Liang Shen

“…The natural isoquinoline alkaloid berberine possesses potential to treat Alzheimer's disease (AD) by targeting multiple pathogenic factors. …”
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Medicinal Effect, In Silico Bioactivity Prediction, and Pharmaceutical Formulation of Ageratum conyzoides L.: A Review by Jasvidianto C. Kotta, Agatha B. S. Lestari, Damiana S. Candrasari, Maywan Hariono

“…The essential oil contains phytochemicals such as phenol, phenolic ester, and coumarin, whereas many compounds can been identified in the whole part such as terpenoid, steroid, chromene, pyrrolizidine alkaloid, and flavonoid. Empirically, this herb has been used as an antihemorrhagic, antiseptic, antileprosy, and wound-healing agent. …”
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David Slays Goliath: Exceptional Efficacy of Oral Vinorelbine in Conquering Metastatic Finger Angiosarcoma by Te-Lin Hsu, San-Chi Chen

“…Vinorelbine, a vinca alkaloid, is listed as supportive care in AS for patients unsuitable for intensive chemotherapy or who are heavily treated. …”
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Piperine: Chemical, biological and nanotechnological applications by Quijia Christian Rafael, Araujo Victor Hugo, Chorilli Marlus

“…Piperine (PIP) is an alkaloid present in several species of piper, mainly Piper nigrum Linn. and P. longum, among other species. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“…All compounds used in the experiment exhibited a cytotoxic effect on the HeLa cell line. Berberine alkaloid showed the most pronounced cytotoxic effect on the HeLa line as recorded by all methods used in the study. …”
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INVESTIGATING CHOLAGOGUE AND CHOLERETIC ACTIVITY OF PEUMUS BOLDUS by Raphael S. F. Silva, Marcus Vinícius H. Faria, Joyce F. S. D. de Almeida, Tanos C. C. França

“…This study aimed to utilize molecular modeling and theoretical chemistry methods to contribute to the elucidation of the mechanism of action of boldine, an alkaloid present in the Peumus boldo plant. Boldo holds a special place in traditional medicinal practices throughout Brazil and has been officially recognized as medicinal plant. …”
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Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Ibogaine, a psychoactive alkaloid, has been proposed as a potential neuroregenerative agent due to its multifaceted pharmacological profile. …”
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Antibacterial and Oxacillin Resistance Reversing Effect of Harmaline in Different Strains of Staphylococcus Aureus by Zaid Ibraheem

“…Background: Harmaline is a naturally occurring indole alkaloid with many medicinal effects. Its antimicrobial effect against different pathogens has been reported previously.Objective: To explore the ability of harmaline to revers oxacillin resistance in the methicillin-resistant strain of Staphylococcus aureus (MRSA).Materials and methods: Briefly, 124 isolates of MRSA were procured from different wards of the Medical Complex City, Baghdad, Iraq. …”
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Anticalculi and antibacterial activity of methanol extract of Holothuria atra by Irwan Irwan, Jefri Saputra Mulia, Softyatuddin Karina, Eli Nurliza

“…Extraction was performed using the maceration method with methanol as the solvent over a period of 72 hours The analysis revealed the presence of four bioactive components in the methanol fraction: alkaloid, triterpenoids, flavonoids, and saponins. …”
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Novel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA by Yi-ning Zhong, Yan Zhang, Yun-qiong Gu, Shi-yun Wu, Wen-ying Shen, Ming-xiong Tan

“…Tryptanthrin is one of the most important members of indoloquinoline alkaloids. We obtained this alkaloid from Isatis. Two novel FeII and CoII complexes of tryptanthrin were first synthesized. …”
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Keefektivan Ekstrak Daun Sirih Hutan Sebagai Pengendali Serangan Hama Penggerek Buah Kopi (Hypothenemus hampei Ferrari) di Lapangan by John Agus Sahputra Pardosi, Arif Ravi Wibowo, Ebenezer Muaratama Sibarani

“…One such botanical pesticide is derived from the Piper aduncum L. plant, which contains various compounds including dilapiol, piperamidin alkaloid, flavonoids, saponins, steroids, polyphenols, tannins, and terpenoids. …”
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Severe Neurotoxicity due to Atropa belladonna Poisoning: A Case Report and Literature Review by Seyed Javad Boskabadi, Sima Ramezaninejad, Zakaria Zakariaei

“…The toxic effects of A. belladonna are attributable to its alkaloid content, which possesses potent anticholinergic properties. …”
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Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress by Md. Yusuf Al-Amin, Amitav Lahiry, Rafia Ferdous, Md. Kamrul Hasan, Md. Abdul Kader, AHM Khurshid Alam, Zahangir Alam Saud, Md. Golam Sadik

“…The phytochemical profile revealed the high content of polyphenolics and alkaloids in the chloroform fraction. Pearson’s correlation studies showed a significant association of anticholinesterase and antioxidant activity with alkaloid and phenolic contents. …”
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Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis by Su Zhang, Quan-Cheng Kan, Yuming Xu, Guang-Xian Zhang, Lin Zhu

“…Matrine (MAT), a quinolizidine alkaloid derived from the herb Radix Sophorae Flave, has been recently found to suppress clinical EAE and CNS inflammation. …”
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Larvacide Activity of Tumih (Combretocarpus rotundatus (Miq.)Danser) Leaf Extracts against Aedes aegypti by Renhart Jemi, Royda Dara Ertini Damanik, Lies Indrayanti

“…Danser leaves contained alkaloids, flavonoids, saponins, and tannins. Larvicidal test conducted on the extracts exhibited an effect on the mortality levels against Aedes aegypti larvae. …”
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Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell by Nurhayati A.P.D., Fatoni M., Santoso M., Wati F.A.

“…Trisindoline is an indole trimer alkaloid natural compound that provide a cytotoxic effect on cancer cells. …”
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