Analyses of Total Alkaloid Extract of Corydalis yanhusuo by Comprehensive RP × RP Liquid Chromatography with pH Difference by Xiaodong Wei, Hongling Shen, Lijun Wang, Qingyan Meng, Wenjie Liu

“…With a pH value of 10.5, most alkaloids appear in the form of neutral molecules possessing high retention factors based on their polarity, while the alkaloid polarity order is changed when the pH value decreased to 3.0. …”
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An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with Pyrrolizidine Alkaloids by Faizullah Kakar, Zarif Akbarian, Toby Leslie, Mir Lais Mustafa, John Watson, Hans P. van Egmond, Mohammad Fahim Omar, Jawad Mofleh

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Stereospecific α-glucosidase inhibition, kinetics, and molecular docking studies on isolated diastereomeric alkaloids from Uncaria longiflora by Nurul Aina Suzlin Sulaiman, Muhammad Farhan Syakir Nor Azman, Mohd Fadhlizil Fasihi Mohd Aluwi, Zainul Amiruddin Zakaria, Mohammad Jemain Mohammad Ridhwana, Fatimah Salim

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Diastereodivergent Construction of Octahydrophenanthridinone and Octahydrophenanthridine Cores by Chunzhao Sun, Hiromichi Nishikawa, Tsubasa Inokuma, Ken-ichi Yamada

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Five New Indole Alkaloid Derivatives from Deep-Sea Fungus <i>Aspergillus fumigatus</i> AF1 by Lai-Hui Dai, Gao-Rong Zhang, Yang-Hui Ou, Xiao-Jing Liu, Hong-Liang Yao, Wen-Hao Hu, Hou-Jin Li, Wen-Jian Lan

“…One new gliotoxin derivative fumianthrogliotoxin (<b>1</b>), one new indoquizoline alkaloid <i>N</i>3-(methyl propionate) indoquizoline (<b>2</b>), and three novel indole alkaloids, anthroxyindole (<b>3</b>), (±)-asperfumiindole A (<b>4</b>), and (±)-asperfumiindole B (<b>5</b>), together with 16 known compounds (<b>6</b>–<b>21</b>), were isolated from the culture of deep-sea derived fungus <i>Aspergillus fumigatus</i> AF1. …”
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Integrated in silico and in vitro exploration of the anti-VEGFR-2 activities of a semisynthetic xanthine alkaloid inhibiting breast cancer. by Eslam B Elkaeed, Hazem Elkady, Ahmed M Khattab, Reda G Yousef, Hanan A Al-Ghulikah, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed A Elkady, Ahmed M Metwaly, Ibrahim H Eissa

“…This study presents T-1-NBAB, a new compound derived from the natural xanthine alkaloid theobromine, aimed at inhibiting VEGFR-2, a crucial protein in angiogenesis. …”
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The Elevation of LC-ESI-Q-TOF-MS Response in the Analysis of Isoquinoline Alkaloids from Some Papaveraceae and Berberidaceae Representatives by Wirginia Kukula-Koch

“…Twelve pharmacologically important isoquinoline alkaloids from four groups, aporphines, benzylisoquinolines, protoberberines, and benzophenanthridines, present in these traditionally used plant species were quantitatively determined in each studied sample, providing their alkaloid profile. …”
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In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS-CoV-2 RNA-Dependent RNA Polymerase by Rishab Marahatha, Asmita Shrestha, Kabita Sharma, Bishnu P. Regmi, Khaga Raj Sharma, Pramod Poudel, Ram Chandra Basnyat, Niranjan Parajuli

“…The molecular docking analysis predicted that naturally occurring alkaloids can bind with RNA-dependent RNA-polymerase (RdRP). …”
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Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells by Kolawole A. Olofinsan, Heidi Abrahamse, Blassan P. George

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Alkaloid content variability in the seeds of narrow-leafed lupine accessions from the VIR collection under the conditions of the Russian Northwest by M. A. Vishnyakova, A. V. Salikova, T. V. Shelenga, G. P. Egorova, L. Yu. Novikova

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Development and Validation of an Ion-Pair HPLC-UV Method for the Quantitation of Quinoline and Indoloquinoline Alkaloids in Herbal and Pharmaceutical Antimalarial Formulations by Samuel Oppong Bekoe, Emmanuel Orman, Samuel Awenteka Adjabui, Abena Amponsaa Brobbey, James Oppong-Kyekyeku, Kwabena Frimpong-Manso Opuni, Noble Kuntworbe, Samuel Asare-Nkansah

“…An HPLC method targeting quinoline and indoloquinoline antimalarial alkaloids was developed, validated, and applied to evaluate herbal and pharmaceutical antimalarial formulations (HPAFs) and starting materials (APIs). …”
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NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots by Muhammad Alamzeb, Muhammad Omer, Mamoon Ur-Rashid, Muslim Raza, Saqib Ali, Behramand Khan, Asad Ullah

“…In search for new and effective drugs from natural sources bioassay-guided fractionation and isolation of Berberis glaucocarpa Stapf roots bark resulted in the isolation and characterization, on the basis of 1D and 2D NMR data, of two bisbenzylisoquinoline alkaloids, oxyacanthine (1) and tetrandrine (2), followed by urease inhibition studies. …”
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Antidepressant- and Anxiolytic-like Effects in Mice of Alkaloids from Aerial Parts of <i>Argemone platyceras</i> Link & Otto by Mayra Beatriz Gómez-Patiño, Rosa Estrada-Reyes, Héctor Hugo Hernández-Mendoza, Ángela Suarez-Rojas, Daniel Arrieta-Baez

“…<b>Methods:</b> a standardized acidic method to obtain alkaloids was used to obtain an extract (AlkExt), which was tested in adult male Swiss Webster mice in the tail suspension (TST) and forced swimming (FST) tests. …”
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Pengaruh Pemberian Ekstrak Daun Pandan Wangi (Pandanus Amarillyfolius Roxb) terhadap Berat Testis dan Diamater Tubulus Mencit (Mus Musculus) by Lili Fajria

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Corrigendum to “Intraspecific and Intracolonial Variation in the Profile of Venom Alkaloids and Cuticular Hydrocarbons of the Fire Ant Solenopsis saevissima Smith (Hymenoptera: Formicidae)” by Eduardo Gonçalves Paterson Fox, Adriana Pianaro, Daniel Russ Solis, Jacques Hubert Charles Delabie, Bruno Cunha Vairo, Ednildo de Alcântara Machado, Odair Correa Bueno

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Identification and Simultaneous Determination of the Main Toxical Pyrrolizidine Alkaloids in a Compound Prescription of Traditional Chinese Medicine: Qianbai Biyan Tablet by Mengting Yang, Daopeng Tan, Anjing Lu, Lin Qin, Changhong Wang, Hua Ling, Yanliu Lu, Yuqi He

“…Several pyrrolizidine alkaloids (PAs) were reported in Senecio scandens and others of Senecio species. …”
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Protective Effects and Mechanisms of Dendrobium nobile Lindl. Alkaloids on PC12 Cell Damage Induced by Aβ25-35 by Yuan Liu, Tingting Pi, Xiaohui Yang, Jingshan Shi

“…To observe the protective effects of Dendrobium nobile Lindl. alkaloids (DNLA) on Aβ25-35-induced oxidative stress and apoptosis in PC12 cells explore its possible protective mechanisms. …”
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Selection of an optimal method for screening the collection of narrow-leaved lupine held by the Vavilov Institute for the qualitative and quantitative composition of seed alkaloids by A. V. Kushnareva, Т. V. Shelengа, I. N. Perchuk, G. P. Egorova, L. L. Malyshev, Yu. A. Kerv, A. L. Shavarda, M. A. Vishnyakova

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Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus <i>Aspergillus</i> sp. Strain SF-7367 by Zhiming Liu, Chi-Su Yoon, Thao Quyen Cao, Hwan Lee, Il-Chan Kim, Joung Han Yim, Jae Hak Sohn, Dong-Sung Lee, Hyuncheol Oh

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Intra- and inter-plant variability of quinolizidine alkaloids in narrow-leaf lupin seeds, grown under different day/night cycles by Tawfeek Khedr, Ling-Ling Gao, Lars G. Kamphuis, Angéla Juhász, Michelle L. Colgrave

“…Inconsistent fluctuation of quinolizidine alkaloid (QA) content in lupin seeds is often observed, sometimes surpassing safe thresholds (>200 mg/kg) yet lacks a clear explanation. …”
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