Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

“…IntroductionTriple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer resistant to endocrine and targeted therapies. …”
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Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review by ZHANG Wangru, CHEN Yuanyuan, LI Zhiping, MENG Jian

“…A craniomaxillofacial CT scan revealed that the tumor had grown aggressively, resulting in destruction of the skull base. …”
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Cross-Gendering the Racial Memory by Marlon B. Ross

“…On the one hand, Gaines’s iconography has the benefit of disturbing and subverting the normatively masculine stance of black nationalism by figuring a she/male whose cross-gendering is less aggressively patriarchal in size and intent, more ambivalently feminine in spirit and form. …”
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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer by Xudong Li, Jingjing Ge, Mengdi Wan, Tongtong Feng, Xiaoqian Li, Haibo Zhang, Zhangyan Wang, Yongsheng Gao, Meiting Chen, Fei Pan

“…The copper transporter, solute carrier family 31 member 1 (SLC31A1), has been associated with tumor aggressiveness and unfavorable outcomes in various types of tumors. …”
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Sistemas Fisiográficos del Área Natural Protegida "Valle Cretácico"; Provincia de Río Negro by Nora Romina Solorza, Marcos Damián Mare

“…As an example, it is enough to mention the practice of not regulated sport activities that are aggressive for environment, which contribute to accelerate erosion processes, loss of vegetation and soils, etc., while the unplanned urban development characterized by the lack of basic services in the suburbs, has led to a high rate of extraction of wood resources of the bush, the emergence of unauthorized micro rubbish dumps, greater frequency in the fire occurrence, etc. …”
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A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy by Robert Hodgson, Matthew Walton, Helen Fulbright, Laura Bojke, Ruth Walker, Alexis Llewellyn, Sofia Dias, Lesley Stewart, David Steel, John Lawrenson, Tunde Peto, Mark Simmonds

“…However, anti-vascular endothelial growth factor drugs are expensive relative to current care options, and it is unclear whether this additional cost is justified when the immediate risk of vision loss is lower compared to patients with more aggressive ophthalmological conditions. Objective To systematically review the evidence supporting the cost-effectiveness of alternative treatments for diabetic retinopathy. …”
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Impact of COVID-19 on Corporate Cash Holdings and Speed of Adjustment by Abbas Aflatooni, Mohammad Khatiri, Farzad Eivani

“…The observed increases in cash holdings and adjustment speeds suggested that Iranian firms adopted more aggressive cash management strategies to navigate the heightened uncertainty and financing constraints imposed by the COVID-19 pandemic. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…COVID-19 is a new virus, very aggressive, with a high level of contagiousness and its capacity to be transmitted has been probably underestimated. …”

Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…[xxi] Additionally, the medical records of Black patients are 2.5 times more likely to contain negative descriptors like non-compliant, non-adherent, aggressive, unpleasant, and hysterical than those of white patients.…”
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