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1841
Monitoring poultry social dynamics using colored tags: Avian visual perception, behavioral effects, and artificial intelligence precision
Published 2025-01-01“…Additionally, fewer aggressive interactions were observed in groups with orange tags compared to groups with other colors, except for red. …”
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1842
Genomic Alterations in Primary Gastric Adenocarcinomas Correlate with Clinicopathological Characteristics and Survival
Published 2004-01-01“…Interestingly, gain of 1q32.3 and loss of 18q22.1 are associated with a bad prognosis indicating that these regions could harbour gene(s) that may determine aggressive tumour behaviour and poor clinical outcome.…”
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1843
Prognostic and clinicopathological role of soluble programmed cell death ligand-1 in patients with diffuse large B-cell lymphoma: a meta-analysis
Published 2025-01-01“…Elevated sPD-L1 levels are closely related to factors representing disease aggressiveness in DLBCL.…”
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1844
Case report: PD-L1-targeted high-affinity natural killer cells and IL-15 superagonist N-803-based therapy extend overall survival of advanced metastatic pancreatic cancer patients
Published 2025-01-01“…BackgroundMetastatic pancreatic cancer (mPC) is an aggressive form of cancer with a poor prognosis and few therapeutic options after failure of the second-line treatment. …”
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1845
Free Fatty Acids in CSF and Neurological Clinical Scores: Prognostic Value for Stroke Severity in ICU
Published 2020-01-01“…It might be a useful biomarker for early detection of high-risk patients for poor outcome and hence more aggressive treatment.…”
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1846
Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center.
Published 2025-01-01“…GBM is known for its aggressive nature and poor prognosis, with most patients experiencing tumor recurrence despite initial treatments. …”
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1847
Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4
Published 2025-02-01“…Pancreatic cancer (PC) is a leading cause of cancer mortality with high aggressiveness. Gemcitabine (GEM) is one of primary antineoplastic drugs for PC. …”
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1848
Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets
Published 2025-01-01“…Abstract Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. …”
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1849
Impact of Novel Guidelines on Multifactorial Control and Its Association with Mortality in Adult Patients with Hypertension and Newly Diagnosed Type 2 Diabetes: A 4-Year Prospectiv...
Published 2021-01-01“…High-risk profile, high mortality, and poor simultaneous control warrant more aggressive cardiorenal protection, focusing more on aging CKD patients with early newly diagnosed diabetes.…”
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1850
Novel models based on machine learning to predict the prognosis of metaplastic breast cancer
Published 2025-02-01“…Background: Metaplastic breast cancer (MBC) is a rare and highly aggressive histological subtype of breast cancer. There remains a significant lack of precise predictive models available for use in clinical practice. …”
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1851
A Local Adversarial Attack with a Maximum Aggregated Region Sparseness Strategy for 3D Objects
Published 2025-01-01“…The experimental results demonstrate that our attack method achieves both stealth and aggressiveness from different viewpoints. Furthermore, we explore the transferability of the decision regions. …”
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1852
Presenting the entrepreneurship development model in the national oil refining industry with the approach of environmental damage prevention
Published 2024-05-01“…The variable of entrepreneurial development includes 4 dimensions of innovation, risk-taking, pioneering and aggressive competition, and the variable of entrepreneurial development includes 3 dimensions of human orientation, environment orientation, and general indifference. …”
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1853
Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer’s disease: a neuropsychological data-driven approach
Published 2025-02-01“…Abstract Background The clinical presentations of early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease are distinct, with EOAD having a more aggressive disease course with greater heterogeneity. …”
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1854
NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity
Published 2025-02-01“…In contrast, NOX4 overexpression improved survival in mice and synergized with checkpoint blockade, demonstrating a positive effect on anti-tumor immunity.DiscussionThese findings show that NOX4 constrains breast cancer aggressiveness by limiting MYC-driven metabolic adaptations and supporting CD8+ T cell-mediated immunity. …”
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1855
Pancreatoduodenectomy without Vascular Resection in Patients with Primary Resectable Adenocarcinoma and Unilateral Venous Contact: A Matched Case Study
Published 2018-01-01“…The poor prognosis of PDAC is related to the aggressive biology and systemic spread of the tumor, rather than the local control of the disease.…”
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1856
Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance
Published 2024-04-01“…The newly formulated methacrylate-based adhesive capitalizes on free-radical polymerization, sol-gel reactions, and hydrophobicity to provide enhanced mechanical properties at elevated temperatures in wet environments and hydrolytic stability under aggressive aging conditions.…”
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1857
Microenvironmental G protein‐coupled estrogen receptor‐mediated glutamine metabolic coupling between cancer‐associated fibroblasts and triple‐negative breast cancer cells governs t...
Published 2024-12-01“…Abstract Background Triple‐negative breast cancer (TNBC) is a particularly aggressive type of breast cancer, known for its lack of effective treatments and unfavorable prognosis. …”
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1858
PET/CT-derived coronary calcium score may predict cardiac complications in anthracycline-treated patients with lymphoma
Published 2025-02-01“…In noncancer populations, coronary artery calcium scoring (CACS) effectively identifies individuals who may benefit from aggressive CVR modification to lower the risk of cardiovascular events. …”
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1859
Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival
Published 2025-02-01“…Abstract Diffuse large B-cell lymphoma (DLBCL) is an aggressive hematopoietic neoplasm that affects humans as well as dogs. …”
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1860
Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study
Published 2021-12-01“…Introduction Plasmablastic lymphoma (PBL), an extremely rare subtype of B-cell non-Hodgkin lymphoma (NHL), is characterized by aggressiveness, rapid progression and a bleak prognosis. …”
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