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1621
The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer
Published 2015-12-01“…The data obtained suggest that HRAS and KRAS gene mutations may characterize alternative pathways of bladder cancer pathogenesis: HRAS mutations indicating benign and KRAS mutations, aggressive disease course.…”
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1622
Étude multicritères sur le passage à un régime sans fruits chez les Cébidés et les Cercopithécidés
Published 2024-11-01“…Nutrition and ethology was monitored, including an assessment of the nutritional composition of diets before, during and after diet change; monitoring of faeces consistency; observation of feeding choices; and the occurrence of aggressive behaviour and vocalisations by scan sampling. …”
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1623
The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review
Published 2025-01-01“…Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. Aggressive therapy should be pursued to effectively manage disease activity in RA patients, while also maintaining constant vigilance for early signs of infections. …”
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1624
Women's Quality of Life After Surgical Treatment for Breast Cancer
Published 2023-10-01“…<strong>Foundation</strong>: breast cancer requires aggressive treatments such as mastectomy or lumpectomy, followed by radiotherapy or chemotherapy. …”
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1625
Upregulated Solute Carrier SLC39A1 Promotes Gastric Cancer Proliferation and Indicates Unfavorable Prognosis
Published 2022-01-01“…High SLC39A1 is critical for a more aggressive tumor phenotype by promoting cell proliferation and invasion. …”
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1626
Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas
Published 2007-01-01“…Background: Hypoxia modifies the phenotype of tumors in a way that promotes tumor aggressiveness and resistance towards chemotherapy and radiotherapy. …”
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1627
Levetiracetam Induced Behavioral Abnormalities in a Patient with Seizure Disorder: A Diagnostic Challenge
Published 2020-01-01“…This research describes the case of a 28-year-old woman with seizure disorder and a psychiatric history of schizoaffective disorder who developed aggressive behavior, paranoia, and severe hostility following administration of Levetiracetam 750 mg orally twice daily. …”
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1628
Digital Gangrene: An Unusual Manifestation of Non-Hodgkin Lymphoma
Published 2022-01-01“…The clinical picture varies from indolent to aggressive presentation and nodal (lymphadenopathy) to extranodal (central nervous system, gastrointestinal, cutaneous plaque, or ulcer) involvement. …”
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1629
Nanoparticles assisted drug delivery for effective management of Glioblastoma
Published 2025-01-01“…Glioblastoma multiforme (GBM) is one of the most aggressive forms of primary brain tumor with a dire prognosis due to its heterogeneity, invasive nature, and resistance to conventional therapies. …”
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1630
Sex differences in borderline personality disorder: A scoping review.
Published 2022-01-01“…Males with BPD were more likely to present externalizing symptoms (e.g., aggressiveness) and comorbid disorders (e.g., substance use), while females with BPD were more likely to present internalizing symptoms (e.g., affective instability) and comorbid disorders (e.g., mood and eating disorders). …”
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1631
HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
Published 2021-01-01“…Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. …”
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1632
Machine learning insights into early mortality risks for small cell lung cancer patients post-chemotherapy
Published 2025-01-01“…IntroductionSmall cell lung cancer (SCLC) is a highly aggressive form of lung cancer, and chemotherapy remains a cornerstone of its management. …”
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1633
FOXP3 as a prognostic marker and therapeutic target in immunogenic cell death modulation for clear cell renal cell carcinoma
Published 2025-01-01“…Evaluating ICD patterns in ccRCC may guide patient-specific interventions, paving the way for improved management of this aggressive cancer.…”
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1634
The narrative of the «Northern Territories» in the socio-political discourse of contemporary Japan
Published 2024-10-01“…Of particular importance from the point of view of the emotional effect on public consciousness are the theses that the Southern Kurils are the “ancestral territory of Japan,” that the USSR committed aggressive and unfair actions against Japan during World War II, and modern Russia did not correct them, and that the Japanese natives of the Southern Kurils experience enormous moral suffering, not having the opportunity to freely visit the graves of their ancestors. …”
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1635
Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer?
Published 2025-01-01“…This review also raises the possibility of using AR splice variants in predicting tumor aggressiveness. From the settings of developing nations, this may provide useful insight by integrating recent advances in AR-targeted therapies and exploring their translational potential, emphasizing the critical need for further research to optimize AR-based therapeutic strategies for breast cancer management.…”
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1636
Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma
Published 2018-01-01“…Hepatocellular carcinoma is an aggressive malignancy of the liver and is ranked as the sixth most common cancer worldwide. …”
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1637
Squamous Cell Carcinoma of Nasofacial Groove
Published 2024-05-01“…It is usually not life-threatening, though it can be aggressive causing serious complications. However, nasofacial groove is a very uncommon area for the origin of squamous cell carcinoma. …”
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1638
Prognostic value of albumin-bilirubin grade in patients with cholangiocarcinoma: a systematic review and meta-analysis
Published 2025-01-01“…CCA accounts for 10% of primary hepatic cancers and is characterized by its aggressive nature and poor prognosis. This systematic review and meta-analysis aims to assess the prognostic value of the novel hepatic function assessment measure known as albumin-bilirubin (ALBI) grade in patients with CCA. …”
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1639
Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction
Published 2012-01-01“…It has been often described as a low-grade sarcoma although there are certain characteristics like high mitotic activity and the presence of focal regions of Ki67 staining above 25% that correlate with aggressive behavior of the tumor. This is the first case of EMC metastatic to the small bowel to be reported to the medical community.…”
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1640
A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review
Published 2025-01-01“…Introduction: Temporo-insular gliomas, rare brain tumors originating from glial cells, comprise about 30% of brain tumors and vary in aggressiveness from grade I to IV. Despite advancements in neuroimaging and surgical techniques, their management remains complex due to their location near critical cognitive areas. …”
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