Clinicopathological features and evaluation of microsatellite stability of colorectal carcinoma with cribriform comedo pattern by Tuğba Günler, Pinar Karabağli, Hicret Tiyek, Özge Keskin, Muslu K. Körez

“…Conclusion: According to the findings, CRAs with comedo cribriform patterns are tumors with more aggressive features. It can be said that these tumors have a specific molecular feature related to MSS. …”
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Aetiologies and Management of Retropharyngeal Abscess in Paediatric Age Group by Prem Kumar, Abhilasha Somashekhar

“…Five children showed the complications of which 60% of them were infant: Conclusion: The crucial step in infants with RPA is prompt diagnosis and aggressive management. Initial antibiotics should be a broad spectrum until the pus culture sensitivity reports are available. …”
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Inside the impulsive brain: a narrative review on the role of neurobiological, hormonal and genetic factors influencing impulsivity in psychiatric disorders by Hannah Raji, Susha Dinesh, Sameer Sharma

“…While serotonin systems show promise for treating impulsive aggressiveness, challenges encompass intricate hormonal interactions, ethical considerations, limited treatment options, and the necessity for individualized approaches. …”
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Proceedings of clinical trials on bile tract cancer by XIONG Yichen, YANG Ziyi, SANG Yuer, GONG Wei

“…Bile tract cancer (BTC) is aggressive and difficult to diagnose at an early stage. …”
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Regenerative activity of stomach epithelial cells at small-intestinal obstruction by V. Ye. Milyukov, K. K. Nguyen

“…At the same time metabolism of epitheliocytes of coating layer and cervical part cells and cells of cambial fundic part of glands is suppressed most significantly, at preservation of metabolic processes of zymogenic main cells of mucosal glands (pepsinogen­producing cells), i.e. generating aggressive factor. Both at acute strangulation and acute obturation smallintestinal obstruction the most pronounced morphofunctional changes of the stomach mucosa within disease development were observed in the antral region that explains the most frequent localization of acute ulcers in this area. …”
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Predicting survival in malignant glioma using artificial intelligence by Wireko Andrew Awuah, Adam Ben-Jaafar, Subham Roy, Princess Afia Nkrumah-Boateng, Joecelyn Kirani Tan, Toufik Abdul-Rahman, Oday Atallah

“…Abstract Malignant gliomas, including glioblastoma, are amongst the most aggressive primary brain tumours, characterised by rapid progression and a poor prognosis. …”
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Male Perineal Carcinoma: Experience in 4 Cases and Literature Review by Agustín Fraile Poblador, Manuel Hevia Palacios, Manuel Rodríguez Vegas, Alberto Artiles Medina, Enrique Sanz Mayayo, Silvia García Barreras, Guillermo Fernández Conejo, Rafael Rodríguez Patrón, Varona Crespo Constatino, Ana Saiz González, Javier Burgos Revilla

“…Perineal carcinoma of unknown origin is a rare and aggressive disease, so an early diagnosis and adequate treatment are essential to prevent its progression. …”
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Intracranial desmoid tumor simulating a trigeminal schwannoma: case report and literature review by Beatrice Silva Fernandes, Jessica Fernandes Vasconcelos, Paulo Eduardo Goncalves, Joilson Francisco de Souza Junior, Ricardo Queiroz Gurgel, Arthur Maynart Pereira Oliveira

“…Abstract Background Desmoid tumor (DT) is a non-encapsulated and locally aggressive benign neoplasm. Although it does not have malignant behavior, it has a high capacity for local growth. …”
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Outcome for Patients with Triple-Negative Breast Cancer Is Not Dependent on Race/Ethnicity by Quyen D. Chu, Amanda E. Henderson, Fred Ampil, Benjamin D. L. Li

“…Triple negative breast cancer (TNBC) is biologically aggressive and is associated with a worse prognosis. …”
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Implementation of criminal law policy of Ukraine under martial law: a study of negative trends by Pysmenskyy Ye.

“…The following negative features are identified that are inherent in the process of implementing Ukraine’s criminal law policy in the context of a high-intensity war: erroneous and/or unequal application of criminal law norms that are flawed; inability to interpret the Criminal Code of Ukraine using all the appropriate methods; inability (unwillingness) to establish the correlation between the literal legal text and the true meaning of legal norms; attempts to use criminal law to play along with the prevailing moods in society (which are characterized by repressiveness given the conditions of an aggressive war); focusing on formal indicators in combating crime with concentration of efforts on simple cases. …”
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Metallurgical assessment of Al-Zr-Y alloys for laser-based processing by J.T. Hierlihy, I.W. Donaldson, D.P. Bishop

“…The scope of aluminum alloys commercially available for laser-based additive manufacturing is limited yet the demand for them is growing aggressively. In many cases, end-users are particularly interested in those that offer enhanced thermal stability. …”
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Influence of Obesity Parameters on Different Regional Patterns of Lymph Node Metastasis in Papillary Thyroid Cancer by Wan-Xiao Wu, Jia-Wei Feng, Jing Ye, Gao-Feng Qi, Li-Zhao Hong, Jun Hu, Sheng-Yong Liu, Yong Jiang, Zhen Qu

“…However, BMI was not the predictor for aggressiveness of PTC in terms of LNM. Clinical decision-making for regional LNM in PTC patients should consider the factor of obesity.…”
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Legal and Moral Aspects of Confidential Cooperation between Individuals and Law Enforcement Agencies by V. M. Davydiuk

“…It has been established that the involvement of persons, from a moral point of view, into confidential cooperation is determined by: the voluntary nature of such involvement; public duty; perception of appropriate cooperation as the assistance to the community for its proper functioning; compulsory use of confidants for the prevention and detection of latent crimes; counteracting aggressive protection of criminal interests; guaranteeing the public interests by saving the costs for law enforcement function, since the use of confidants is more financially effective than attracting additional law enforcement forces and means.…”
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Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. by Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Bartlomiej Salamaga, Justyna Folkert, Krzysztof Rakus, Magdalena Chadzinska, Jan Potempa, Graham P Stafford, Tomasz K Prajsnar, Craig Murdoch

“…However, the mechanism by which immune cells respond to Pg challenge in vivo remains elusive. Pg produce aggressive proteolytic virulence factors termed gingipains which not only provide nutrients necessary for bacterial growth, but also subvert the host immune response, facilitating bacterial survival. …”
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Negotiation and Procurement Performance in Uganda: A Case Study of Kabale Municipality. by Tayebwa, Newbold

“…The study results from findings on the effects of competitive negotiations on the procurement performance of Kabale Municipal Council were; a competitive negotiation is more focused on a short-term win, competitive negotiation strategies are less likely to concede, and competitive tactics often seek to use intimidation and aggressive threats to drive the other party to make concessions. …”
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Non-Performing Loans and Performance of Financial Institutions in Kabale District by Alex, Semusu

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A rare case of recurrent adenoid cystic carcinoma of the breast with weak hormone receptor positivity by Jonathan W. Ray, MD, Mena Louis, DO, Nathaniel Grabill, MD, Jaime Morel Ruiz, MD, Priscilla Strom, MD

“…Recurrent breast ACC presents management challenges due to rarity and unpredictable behavior. More aggressive surgery and tailored treatment may improve outcomes. …”
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Genotyping and drug susceptibility profiling of Prototheca sp. strains isolated from cases of protothecosis in dogs by Angelika Proskurnicka, Mateusz Iskra, Sylwia Wronka, Zofia Bakuła, Patrizia Danesi, Marconi Rodrigues deFarias, Fábio Vinícius Ramos Portilho, Márcio Garcia Ribeiro, Uwe Rösler, Rui Kano, Richard Malik, Tomasz Jagielski

“…Abstract Background Protothecosis in dogs is a rare, yet emerging disease, distinguished by its often‐aggressive clinical course and high fatality rate. Our study was conducted to enhance treatment protocols for affected dogs by better understanding the genetic diversity and drug resistance patterns of Prototheca species. …”
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Biomonitoring PhIP, a Potential Prostatic Carcinogen, in the Hair of Healthy Men of African and European Ancestry by Robert J. Turesky, Clarence Jones, Jingshu Guo, Kari Cammerrer, Laura A. Maertens, Emmanuel S. Antonarakis, Zhanni Lu, Logan G. Spector

“…Frequent consumption of well-done meats containing 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP), a prevalent HAA that is a prostatic carcinogen in rodents and DNA-damaging agent in human prostate cells, has been linked to aggressive prostate cancer (PC) pathology. African American (AA) men face nearly twice the risk for developing and dying from PC compared to White men. …”
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Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review by Magdalena Maria Pietrzko, Maciej Pietrzko, Wojciech Niemczyk, Dariusz Skaba, Rafał Wiench

“…Greater improvements in clinical and radiological parameters were seen in patients diagnosed with aggressive periodontitis compared to patients with chronic periodontitis. …”
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