A Case of Congenital Brainstem Oligodendroglioma: Pathology Findings and Review of the Literature by Stefan Kostadinov, Suzanne de la Monte

“…The pathological features of the lesion distinguish it from previous reports in which spontaneous regression of pontine gliomas occurred and argue in favor of establishing a tissue diagnosis to plan for aggressive versus conservative management.…”
Get full text

“The Road of War” and “The Path of Peace”: William Morris’s Representation of Violence by Eleonora Sasso

“…Morris’s early romances and the high fantasies develop their own detailed blueprint of wars and battles which reveal to be a broad philosophical meditation on the entire mediaeval vision of man’s aggressive attitude. As part of this overview of the tradition Morris devotes close attention to mediaeval emblems of war displaying considerable ambivalence towards them. …”
Get full text

End-of-life decisions and palliative care in surgical intensive care units by Polona Gams, Anja Kramarič Lozar, Primož Gradišek, Maja Šoštarič

“…In intensive care units the ethical dilemma arises, questioning whether aggressive treatments merely postpone the inevitable end of life and become burdensome to patients. …”
Get full text

Mucoepidermoid Carcinoma of the Lung: A Case Report and Literature Review by S. Alsidawi, J. C. Morris, K. A. Wikenheiser-Brokamp, S. L. Starnes, N. A. Karim

“…Surgical resection is the primary treatment for low-grade MEC with excellent outcomes, while high-grade MEC is a more aggressive form of malignancy. Clinical Case. We report a case of a 46-year-old woman who presented with dyspnea on exertion. …”
Get full text

Acral Lentiginous Melanoma Presenting with Amelanotic Metastasis by Alaka J Mohan, AjithkumarKidanga zhiyathmana, Neelakandhan Asokan

“…Acral melanoma is an aggressive subtype of melanoma which presents on palms soles and nails. …”
Get full text

Epithelioid Angiosarcoma of the Septum Pellucidum by Chiara Baldovini, Matteo Martinoni, Gianluca Marucci

“…Albeit extremely rare, this neoplasia is a potential source of misdiagnosis for other aggressive malignant tumors, and it should be taken into consideration.…”
Get full text

Candidate SNP markers of social dominance, which may affect the affinity of the TATAbinding protein for human gene promoters by I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko

“…The following heuristic hypothesis has been proposed: if an excess of a protein in several animal organs was experimentally identified as physiological marker of increased aggressiveness and if a polymorphism (SNP) can cause superexpression of the human gene homologous of the animal gene encoding this protein, then this polymorphism can be a candidate SNP marker of social dominance, whereas a deficient expression corresponds to subordinate and vice versa. …”
Get full text

Hemorrhagic Longitudinally Extensive Transverse Myelitis (LETM) as a First Presentation of Neuromyelitis Optica Spectrum Disorder (NMOSD): A Case Report and Literature Review by Shima Jahani, Fateme Jamshidi, Abdorreza Naser Moghadasi

“…Even though the patient received aggressive treatment, he showed no significant improvement. …”
Get full text

Surviving the edge: Strategies for maximizing recovery in near-hanging cases: A case series by Arvind Kumar Yadav, Suhas Kumar Mall, Vempalli Nagasubramanyam, Rahul Gupta, Arun Kumar Pandey, Konda Sireesha

“…All our patients presented in very critical condition and were treated with early aggressive management resulting in excellent outcomes.…”
Get full text

Control de Brazilian Pepper-tree by Ken Gioeli, Ken Langeland

“…It describes this shrub or small tree which is one of the most aggressive non-native invaders of mangrove communities and affecting nearly all terrestrial ecosystems in central and southern Florida — its history, habitat, identification, and control.  …”
Get full text

Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature by Elias G. Tzelepis, Elena Barengolts, Steven Garzon, Joseph Shulan, Yuval Eisenberg

“…MSO can occasionally coexist with highly aggressive eutopic thyroid cancer. Although this concurrence is even rarer than MSO, clinicians should routinely investigate for possible synchronous thyroid cancer in all cases of MSO and also consider aggressive postoperative treatment including thyroidectomy and radioiodine ablation therapy in cases of MSO.…”
Get full text

Virtual Violence and New Media Ethics: The Boundary between Legitimate and Harmful Expressions by Hasan Sazali, Abdul Rahman Matondang, Desvi Yanti Mukhtar, Rasyidah Rasyidah

“…The objective of this study is to explore the dynamics of the transition between creative expression and aggressive online behavior, as well as to identify its implications for individuals and society. …”
Get full text

Hypercalcemia and Bone Metastasis in a Case of Large Cell Neuroendocrine Carcinoma With Unknown Primary by Ekrem Yetiskul, Jordyn Salak, Fatema Arafa, Alaukika Agarwal, Amanda Matra, Muhammad Niazi, Marcel Odaimi

“…NETs frequently demonstrate a propensity to metastasize, spreading to diverse anatomical regions such as the liver, lungs, lymph nodes, and bones, illustrating their aggressive nature and the complexity of their management. …”
Get full text

Interventional Treatment of Abdominal Compartment Syndrome during Severe Acute Pancreatitis: Current Status and Historical Perspective by Dejan V. Radenkovic, Colin D. Johnson, Natasa Milic, Pavle Gregoric, Nenad Ivancevic, Mihailo Bezmarevic, Dragoljub Bilanovic, Vladimir Cijan, Andrija Antic, Djordje Bajec

“…It occurs as combination of inflammation of retroperitoneum, visceral edema, ascites, acute peripancreatic fluid collections, paralytic ileus, and aggressive fluid resuscitation. The frequency of ACS in SAP may be rising due to more aggressive fluid resuscitation, a trend towards conservative treatment, and attempts to use a minimally invasive approach. …”
Get full text

Extensive Growth of an Anaplastic Meningioma by Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn

“…With the presented case, we would like to show the aggressive behavior of anaplastic meningiomas in a very illustrative way. …”
Get full text

Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors: A State of the Art Review by Sven-Petter Haugvik, Knut Jørgen Labori, Bjørn Edwin, Øystein Mathisen, Ivar Prydz Gladhaug

“…Over the last decade there has been a noticeable trend towards more aggressive surgery as well as more minimally invasive surgery in patients with PNETs. …”
Get full text

The Role of Targeted Focal Therapy in the Management of Low-Risk Prostate Cancer: Update on Current Challenges by Daniel W. Smith, Diliana Stoimenova, Khadijah Eid, Al Barqawi

“…These men are thus burdened with the morbidities associated with aggressive treatments, commonly incontinence and erectile dysfunction, without receiving a mortality benefit. …”
Get full text

FOX DOMESTICATION: MOLECULAR MECHANISMS INVOLVED IN SELECTION FOR BEHAVIOR by L. N. Trut, Yu. E. Herbeck, A. V. Kharlamova, R. G. Gulevich, A. V. Kukekova

“…Attention is focused on the role of artificial selection in the transformation of behavior of these animals, which has created the unique populations of tame and aggressive foxes. Additional resources were developed to analyze the molecular nature of differences in the behavior of these unique foxes: the meiotic map of the fox genome was constructed, crosses of tame and aggressive animals obtained informative segregating subpopulations, and the formerly applied method of quantification of behavioral phenotypes was improved. …”
Get full text

Clinical Outcome of Patients with Complete Pathological Response to Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancers: The Indian Scenario by Snita Sinukumar, Prachi Patil, Reena Engineer, Ashwin Desouza, Avanish Saklani

“…In the Indian subcontinent, despite younger patients with aggressive tumor biology, outcome in complete responders is good.…”
Get full text

Metaplastic Carcinoma of the Breast with Squamous Differentiation: A Case Report from the University Teaching Hospital of Kigali (CHUK), Rwanda by Delphine Uwamariya, Carine Nyampinga, Anne Yvette Nsenguwera, Belson Rugwizangoga

“…Metaplastic breast carcinoma is a rare and aggressive condition, accounting less than 1% of breast malignancies. …”
Get full text