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22621
Effects of Nicotinamide Riboside Supplementation on Postmortem Mitochondrial Functionality and Apoptotic Activation
Published 2025-01-01“…Background/Objectives: Early postmortem mitochondrial function and apoptotic activation affect meat quality development. Nicotinamide riboside (NR) supplementation to pigs prior to harvest can improve pork color stability, but its mechanism remains unclear. …”
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22622
Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning
Published 2025-01-01“…Moreover, PLAC8 overexpression was found to promote the proliferation of urothelial cells without affecting their migratory ability by inhibiting the Akt/mTOR/PI3K signaling pathway.ConclusionsOur study identifies potential diagnostic candidate genes and reveals the complex immune landscape associated with IC/BPS. …”
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22623
MUC5B modulation of early oral biofilm glucose metabolism
Published 2025-02-01“…IntroductionSalivary mucin MUC5B has been suggested to support eubiosis in early oral biofilms by regulating the attachment of commensals, while downregulating dysbiotic activities related to dental caries development, such as microbial carbohydrate transport and metabolism.MethodsTo investigate how the metabolism of glucose, a potential driver for dental caries, in early mono- and dual-species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates was affected by the presence of the complex salivary mucin MUC5B, this study employed nuclear magnetic resonance (NMR)-based metabolomics with the interpretation of network integration.Results and discussionMUC5B reduced early attachment in the presence of glucose compared with uncoated surfaces but maintained even species distribution. …”
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22624
Progress in phase field research of dead lithium in lithium batteries
Published 2025-03-01“…The phase field method is used to determine how the formation of dead lithium affects the overall life of the battery. The phase field is also used to simulate the long-term behavior of lithium metal anodes to predict the battery life under various operating conditions. …”
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22625
Faktor-Faktor yang Berhubungan dengan Perilaku Seksual Remaja di Kota Padang
Published 2016-08-01“…It can be concluded that adolescent sexual behavior in Padang City be affected by males, high exposure with internet and negative attitude toward sexual behavior. …”
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22626
Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway
Published 2024-12-01“…However, the low maturation rate of AVF severely affects its use in patients. A more comprehensive understanding and study of the mechanisms of AVF maturation is urgently needed.Methods and results In this study, we downloaded the publicly available datasets (GSE119296 and GSE220796) from the Gene Expression Omnibus (GEO) and merged them for subsequent analysis. …”
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22627
Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach
Published 2025-01-01“…MR analyses revealed strong causation between IBS and multisite chronic pain (OR=2.20, 95% CI 1.82 to 2.66), gastro-oesophageal reflux disease (OR=1.31, 95% CI 1.23 to 1.39), well-being spectrum (OR=0.17, 95% CI 0.13 to 0.21), life satisfaction (OR=0.31, 95% CI 0.25 to 0.38), positive affect (OR=0.30, 95% CI 0.24 to 0.37), neuroticism score (OR=1.20, 95% CI 1.16 to 1.25) and depression (OR=1.50, 95% CI 1.37 to 1.66). …”
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22628
Poor sleep quality and associated factors among HIV-positive and negative postpartum women in Addis Ababa, Ethiopia: a comparative cross-sectional study
Published 2025-01-01“…In addition, the condition may worsen among postpartum women living with human immunodeficiency virus (HIV), affecting their capacity to care for their child. Therefore, this study will provide baseline information by assessing the burden of poor sleep quality and associated factors among HIV-positive and negative postpartum women in Addis Ababa, Ethiopia.ObjectiveThe aim of this study was to assess poor sleep quality and its associated factors among HIV-positive and negative postpartum women in Addis Ababa, Ethiopia in 2023.MethodsA comparative cross-sectional study was conducted from 20 March to 20 May 2023, and a systematic random sampling technique was employed to obtain a total of 535 study subjects. …”
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22629
A comparative study of the effect of capsular repair in the Latarjet procedure
Published 2025-01-01“…Capsular repair and arthroscopic approach did not affect the proportion of patients reporting shoulder apprehension (P = 0.52 and 0.48 respectively). …”
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22630
Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats
Published 2019-01-01“…Dietary fatty acids (FAs) affect certain metabolic routes, including pathways controlled by the peroxisome proliferator-activated receptors (PPARs), but tissue-specific effects are not well-defined. …”
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22631
Wnt signaling as a translational target in rheumatoid and psoriatic arthritis
Published 2025-02-01“…Abstract Background Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are chronic inflammatory diseases mainly affecting joints. RA primarily targets the synovial joints and is characterized by cartilage and bone erosion, whereas PsA is associated with skin and nail psoriasis and is characterized by erosive bone damage with an exuberant bone formation and soft tissue involvement. …”
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22632
Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum)
Published 2025-01-01“…We investigated how damage by a generalist herbivore species, the beet armyworm (Spodoptera exigua), affects leaf-stored and emitted volatiles in wild G. hirsutum plants and compared the responses of two known chemotypes. …”
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22633
Values and professional identity of student-age population
Published 2020-03-01“…Changes in value orientations directly affect the professional identity of new generations. …”
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22634
Kinetics, modelling and optimization of Shea butter transesterification via clay doped ionic liquid catalyst
Published 2025-01-01“…Increase in the process parameters significantly affected the yield, with the highest yield of 89.45 % obtained at an agitation of 300rpm while other parameters were kept constant. …”
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22635
Hubungan Pemberian Makanan Tambahan Dini terhadap Status Gizi Bayi Usia 4-6 Bulan di Daerah Pantai Kota Padang Tahun 2013
Published 2015-09-01“…Early<br />supplementary feeding can cause health problems, such as diarrhea, respiratory tract infections, etc., which will affect the nutritional status of infants. The objective of this study was to determine the relationship of early complementary feeding on the nutritional status of infants aged 4-6 months. …”
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22636
Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review
Published 2025-01-01“…Centro de Investigación En Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barakaldo, Bizkaia, Spain; 4Centre for Affective Disorders, Psychological Medicine, Ioppn, King’s College, London, UK; 5Child and Adolescent Mental Health Services, South London and Maudsley NHS Foundation Trust, London, UK; 6Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón School of Medicine, Universidad Complutense, Iisgm, CIBERSAM, Madrid, SpainCorrespondence: Dr Gonzalo Salazar de Pablo, Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience (IoPPN) King’s College London, Room D1.14, Child Psychiatry Building 16 De Crespigny Park, London, SE5 8AB, United Kingdom, Tel +44 0207 848 0002, Email gonzalo.salazar_de_pablo@kcl.ac.ukAbstract: Despite being associated with increased illness severity and suicidality compared to non-psychotic depression, psychotic depression remains under-researched, particularly in adolescents. …”
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22637
Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development
Published 2025-02-01“…Results In vitro screening at one of the institutions identified two fast-acting substances affecting worm physiology (OGHL00022, OGHL00121). The effects of the two lead structures were investigated in more detail by confocal laser scanning microscopy and 5-ethynyl 2´-deoxyuridine (EdU) assays to assess morphological effects and stem cell effects. …”
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22638
Effects of Dual-Site Anodal Transcranial Direct Current Stimulation on Attention, Decision-Making, and Working Memory during Sports Fatigue in Elite Soccer Athletes
Published 2025-01-01“…Background: Sports fatigue in soccer athletes has been shown to decrease neural activity, impairing cognitive function and negatively affecting motor performance. Transcranial direct current stimulation (tDCS) can alter cortical excitability, augment synaptic plasticity, and enhance cognitive function. …”
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22639
Epidemics In The 21st Century: A Multifaceted Challenge
Published 2023-12-01“…Dengue is yet another significant challenge for the healthcare system of many under-developed countries, especially Pakistan, affecting many people each year. Pakistan is experiencing major public health threats in the face of the current massive flood that facilitates the transmission of this deadly disease. …”
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22640
Use of erectile dysfunction treatments after prostate cancer treatment and their perceived impact on men’s sex life: an analysis of patient reported outcome survey data
Published 2025-01-01“…Abstract Background Although sexual dysfunction is a common treatment side-effect affecting men’s quality of life, many prostate cancer patients do not receive or seek out treatments for erectile dysfunction (ED). …”
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