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21261
The interplay between RNA m6A modification and radiation biology of cancerous and non-cancerous tissues: a narrative review
Published 2024-12-01“…In conclusion, enzyme-mediated m6A-modification triggers alterations in target gene expression by affecting the metabolism of the modified RNAs, thus modulating progression and radiosensitivity in cancerous tissues, as well as radiation effects on normal tissues. …”
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21262
A High-Salt Diet Disturbs the Development and Function of Natural Killer Cells in Mice
Published 2020-01-01“…NK cells play a vital role in resisting viruses and preventing the malignant transformation of cells; however, whether HSD affects the development and function of NK cells has not yet been elucidated. …”
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21263
Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s dise...
Published 2025-02-01“…Adult neurogenesis was not affected by genotype. TgF344-AD rats had spatial learning and memory impairments, but this cognitive deficit did not correlate with amyloid plaque number or cellular changes in the brain. …”
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21264
Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?
Published 2021-04-01“…Other novel delivery options may also affect immune responses, including T-cell activation and tumor-antigen presentation changes. …”
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21265
Arsenic inducible islet β-cell dysfunction and ferroptosis through m6A-YTHDF2-dependent CHAC1 enhancement
Published 2025-01-01“…Conversely, arsenic does not affect the expression of the glutathione-cysteine ligase catalytic subunit (GCLC), which is crucial for glutathione synthesis. …”
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21266
Abdominal fat distribution and its relationship to brain changes: the differential effects of age on cerebellar structure and function: a cross-sectional, exploratory study
Published 2013-01-01“…Furthermore, these associations seem to be age dependent, with younger adults’ brains being adversely affected.…”
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21267
Exploring the effects of Tianma Gouteng granules on L-NAME-induced hypertensive rats based on 16S rDNA gene sequencing and metabolomics
Published 2025-01-01“…Conclusions: TG can treat hypertension by affecting differential strains and differential metabolites, providing a scientific basis for guiding the rational use of TG.…”
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21268
Dynamic changes in soil erosion and challenges to grain productivity in the black soil region of Northeast China
Published 2025-02-01“…The average thickness of soil complex erosion reached 48.48 mm/a, affecting 25.23 million hectares and 1.90 million tons grain yield. …”
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21269
Steroid use for established bronchopulmonary dysplasia: study protocol for a systematic review and meta-analysis
Published 2022-06-01“…Introduction Postnatal steroids during the first few weeks of life have been demonstrated to be effective in decreasing the incidence of bronchopulmonary dysplasia (BPD), a serious chronic respiratory condition affecting preterm infants. However, this preventive option is limited by the concern of neurological side effects. …”
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21270
The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials
Published 2025-01-01“…Previous studies have assessed how supplementing with Garcinia cambogia affects glycaemic control and liver enzyme levels; nevertheless, the results were not consistent. …”
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21271
Evaluating the Accessibility of Urban Public Open Spaces Based on an Improved 2SFCA Model: A Case Study Within Chengdu’s Second Ring Road
Published 2025-01-01“…On the demand side, besides population size, the model incorporates the spatial distribution of residents and differences in social characteristics affecting UPOS demand. Results indicate that the improved 2SFCA model, which considers both the attractiveness of UPOS and residents’ demand, significantly enhances the accuracy of accessibility assessments. …”
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21272
Effect of Sodium Azide on Quantitative and Qualitative Stem Traits in the M2 Generation of Ethiopian Sesame (Sesamum indicum L.) Genotypes
Published 2021-01-01“…Traits such as plant height, ground distance to first distance, and internode length were significantly affected by NaN3 treatment. The highest plant height was recorded in the control on Humera 1 and Baha Necho genotypes, while the lowest was observed on Setit 2 and Hirhir treated with the chemical. …”
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21273
Exploring the Impact of Citric Acid on Mitigating Sweet Potato Soft Rot and Enhancing Postharvest Quality
Published 2025-01-01“…Soft rot, caused by the pathogen <i>Rhizopus stolonifer</i>, is a major postharvest disease affecting sweet potato (<i>Ipomoea batatas</i> (L.) …”
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21274
Method and Experimental Research of Transmission Line Tower Grounding Body Condition Assessment Based on Multi-Parameter Time-Domain Pulsed Eddy Current Characteristic Signal Extra...
Published 2025-01-01“…They are important devices; however, in the harsh environment of the soil, they are prone to corrosion or even fracture, which in turn affects the normal utilization of the transmission line, so accurately assessing the condition of grounding bodies of the power grid is critical. …”
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21275
Fusobacterium nucleatum upregulates the immune inhibitory receptor PD-L1 in colorectal cancer cells via the activation of ALPK1
Published 2025-12-01“…These results aid in our understanding of the mechanisms by which F. nucleatum can affect tumor development and therapy and pave the way for future therapeutic approaches.…”
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21276
Oridonin ameliorates renal fibrosis in diabetic nephropathy by inhibiting the Wnt/β-catenin signaling pathway
Published 2024-12-01“…Here, we investigated the mechanism through which Ori affects the Wnt/β-catenin signaling pathway in diabetic rats and human proximal tubular epithelial cells (HK-2) exposed to high glucose (HG) levels. …”
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21277
Role of Gender in Shaping Consumer Responses to Doctor Influencer: Insights into Brand Perceptions and Repurchase Intentions in the Indonesian Mineral Water Industry
Published 2024-09-01“…However, gender has emerged as a key moderator influencing how attractiveness affects brand perception. Contrary to expectations, familiarity with the influencer has no significant effect on brand attitudes, suggesting a shift in digital audience engagement. …”
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21278
A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes
Published 2015-01-01“…The C57BL/6 mouse model of diet-induced obesity has been used to study the mechanisms by which altered glucose homeostasis affects bone mass and quality, but genetic variations in substrains of C57BL/6 may have confounded data interpretation. …”
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21279
In Vitro Biological Activity of Beauveria bassiana, Beauveria peruviensis, and Metarhizium sp. against Hypothenemus hampei (Coleoptera: Curculionidae)
Published 2023-01-01“…However, coffee production is affected by the coffee berry borer (Hypothenemus hampei). …”
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21280
South Atlantic subtropical anticyclone responses to stratospheric aerosol injection
Published 2025-01-01“…However, little is known about how the combination of global warming and climate intervention affects this system. To address this, SASA was identified from 2015 to 2099 in a set of projections with and without stratospheric aerosol injection (SAI). …”
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