Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes by Ali Tawbeh, Catherine Gondcaille, Fatima-Ezzahra Saih, Quentin Raas, Damien Loichot, Yannick Hamon, Céline Keime, Alexandre Benani, Francesca Di Cara, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

“…These findings demonstrate that peroxisomal impairments in microglia exacerbate inflammatory response and ROS/NO production, affecting the survival of neurons and oligodendrocytes, as well as neuronal morphology and function. …”
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Global burden of osteoarthritis from 1990 to 2019 attributable to high body mass index by Siming Yang, Licheng Zhou, Wanchen Gong, Bin Guo, Linfeng Wang

“…In particular, this burden was higher in women than in men; primarily affected middle-aged and older adults; and was generally greater in high-SDI regions than in low-SDI regions.…”
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The potential of recycling wool residues as an amendment for enhancing the physical and hydraulic properties of a sandy loam soil by Ahmed Abdallah, Francesca Ugolini, Silvia Baronti, Anita Maienza, Francesca Camilli, Laura Bonora, Francesca Martelli, Jacopo Primicerio, Fabrizio Ungaro

“…Despite the high capacity of absorbing water, SWRs affected the water movement of the soil more than its water retention.…”
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Feather hydrolysate as a promising nitrogenârich fertilizer for greenhouse lettuce cultivation by Lisiane Sobucki, Rodrigo Ferraz Ramos, Elci Gubiani, Gustavo Brunetto, Douglas Rodrigo Kaiser, Daniel Joner Daroit

“…Lettuce growth was negatively affected by PL when compared to controls. Conclusion FH, obtained from microbial processing of abundant and inexpensive feathers, could be a candidate N-rich fertilizer for lettuce cultivation.…”
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Antivirulence drugs offer a new approach to treating bacterial infections by targeting specific virulence factors without affecting bacterial growth, thus helping to combat infection without exerting selective pressure on bacteria or inducing resistance. …”
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A Low-Cost Layered Double Hydroxide (LDH) Based Amperometric Sensor for the Detection of Isoproturon in Water Using Carbon Paste Modified Electrode by Herve Leclerc Tcheumi, Aude Peggy Kameni Wendji, Ignas Kenfack Tonle, Emmanuel Ngameni

“…Other parameters that can affect the stripping response (preconcentration time, pH of detection medium, and LDH loading within the paste) were investigated to optimize the proposed sensor. …”
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Precision Adverse Drug Reactions Prediction with Heterogeneous Graph Neural Network by Yang Gao, Xiang Zhang, Zhongquan Sun, Payal Chandak, Jiajun Bu, Haishuai Wang

“…By leveraging edges in the graph, crucial connections are captured such as a patient being affected by diseases, taking specific drugs, and experiencing ADRs. …”
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Incidence and outcomes of neonatal group B streptococcal sepsis in Qatar-a multicentre study by Sajid Salim Thyvilayil, Anvar Paraparambil Vellamgot, Khalil Salameh, Sudheer Babu Kurunthattilthazhe, Abdurahiman Elikkottil, Liliana Llerena Dominguez, Dhanya Banarjee

“…A secondary aim was to describe the outcomes of the affected babies. Materials and Methods A retrospective chart review of all neonates born during the study period was performed with the help of medical records departments of the four main maternity hospitals in Qatar, where > 90% of the births occurred. …”
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Lyme neuroborreliosis as initial expression of Lyme disease in an elderly patient by Emidio Mata, Bárbara Lage Garcia, André Pereira, Joana Rego, Flávia Santos, Carlos Fernandes, Jorge Cotter

“…Background: Lyme disease (LD) is a multisystemic infection caused by Borrelia burgdorferi and transmitted by Ixodes ticks, affecting the skin, nervous system, heart and joints. …”
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Deficit Irrigation Response and Climate Resilience of Mediterranean Tomato Landraces by Yüksel Tüzel, Hüseyin Biyke, Omar S. Harouna, Tunç Durdu, Mahmut Tepecik, Gölgen B. Oztekin, Ulaş Tunalı, Nazim S. Gruda

“…The results revealed that water deficit adversely affected total and marketable yields, plant growth, and biomass while enhancing some specific quality parameters. …”
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Using stone dust as an improvement material for cement gravel column by Raksiri Sukkarak, Pornkasem Jongpradist, Panich Voottipruex, Pitthaya Jamsawang, Suraparb Keawsawasvong, Teerawut Pansuwannakun, Ittipon Meepon

“…The unconfined compressive strength (UCS) test showed that 10 %-20 % cement-content CG samples exhibited compressive strengths between 12 and 83 ksc, meeting low-to-medium load-bearing construction requirements. The stone dust affects the failure mechanisms of the CG sample, which is discussed. …”
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Memory B cells and their transcriptomic profiles associated with belimumab resistance in systemic lupus erythematosus in the maintenance phase by Takeshi Iwasaki, Takeshi Iwasaki, Hajime Yoshifuji, Koji Kitagori, Shuji Sumitomo, Shuji Akizuki, Ran Nakashima, Hideaki Tsuji, Ryosuke Hiwa, Mirei Shirakashi, Kosaku Murakami, Akira Onishi, Hideo Onizawa, Masao Tanaka, Fumihiko Matsuda, Akio Morinobu, Koichiro Ohmura, Koichiro Ohmura

“…This was also associated with changes in disease activity and glucocorticoid dose at six months compared with baseline. Belimumab did not affect memory B cell proportion during the treatment time course, in contrast to naïve B cells. …”
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Seasonal Changes in Climate Variables in Rainfed Crop Areas in the Lerma-Chapala-Santiago Basin, Mexico by Raymundo Ordoñez-Sierra, Miguel A. Gómez-Albores, Carlos Díaz-Delgado, Luis Ricardo Manzano-Solís, Angel Rolando Endara-Agramont, Carlos Alberto Mastachi-Loza

“…Additionally, rainfall showed an annual decrease of approximately 50 mm in all RCAs, which can affect the phenological development of crops during critical stages (emergence through flowering). …”
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Flexible reproductive seasonality in Africa-dwelling papionins is associated with low environmental productivity and high climatic unpredictability by Dezeure, Jules, Dagorrette, Julie, Burtschell, Lugdiwine, Chowdhury, Shahrina, Lukas, Dieter, Swedell, Larissa, Huchard, Elise

“…In order to predict how changes in seasonality might affect these animals, it is important to understand which aspects of their diverse patterns of reproductive phenology are linked to either the equally diverse patterns of rainfall seasonality (within-year variations) or instead the marked climatic unpredictability (year-to-year variations) occurring across the intertropical belt. …”
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Integrating river transport processes and seasonal dynamics to assess watershed nitrogen export risk by Jian Peng, Tianhan Lan, Jiabin Wang, Pei Xia, Huining Zheng

“…Excessive nitrogen exported to water bodies affects the balance of ecosystem and poses a threat to human health. …”
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CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence by Zijian Qiu, Jiaji Wu, Guanchao Pang, Xia Xu, Jun Lin, Pingli Wang

“…CD34-MVD is an independent risk factor affecting postoperative tumor recurrence in patients with LUAD and can be used as a prognostic indicator for this group of patients.…”
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Mixed vulnerabilities: the biological risk of high parity is aggravated by emergency referral in Benin, Malawi, Tanzania and Uganda by Manuela Straneo, Lenka Beňová, Thomas van den Akker, Muzdalifat S. Abeid, Elizabeth Ayebare, Jean-Paul Dossou, Greta Handing, Bianca Kandeya, Andrea B. Pembe, Claudia Hanson

“…High parity (≥ 5 previous births) is an underemphasized biological vulnerability linked to poverty and affecting a sizeable proportion of SSA births. Despite increased risk, high parity women rarely use hospitals for childbirth. …”
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Comparison of clinical variables and outcome of 2 natural equine herpesvirus myeloencephalopathy outbreaks induced by equine herpesvirus‐1 A2254/N752 strain in sport horses by María de laCuesta‐Torrado, Ana Velloso Alvarez, José Miguel Cárdenas‐Rebollo, Patricia Neira‐Egea, Valentina Vitale, Juan Cuervo‐Arango

“…Animals Twenty‐five and 10 horses affected during 2 natural EHM outbreaks were admitted to a veterinary teaching hospital (VTH) in 2021 and 2023, respectively. …”
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Teaching healthy lifestyle behaviors based on philosophical thinking to preschool children: a randomized controlled trial by Zakieh Khoramaki, Mahin Nazari, Leila Ghahremani, Mohammad Hossein Kaveh, Abdolrahim Asadollahi

“…Evidence indicates that the incorporation of philosophical thinking—encompassing critical, creative, and compassionate thought—can significantly contribute to children’s cognitive and moral growth, thereby positively affecting their health-related decisions. This research evaluated the effects of imparting healthy lifestyle practices through philosophical thinking to preschool children. …”
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Failure Mechanism and Kinematics of the Deadly September 28th 2016 Sucun Landslide, Suichang, Zhejiang, China by Hai Tian, Jianjun Gan, Hui Jiang, Chun Tang, Changtai Luo, Chenghui Wan, Bin Xu, Faliang Gui, Chengyi Liu, Nian Liu

“…Such loose accumulation in upslope may saturate partially or completely when the stability of their accumulation dam is distributed or affected by rainfall. We present a case study with respect to the southern Wuyi Mountain located in eastern China, where the wet and rainy climate has led to dozens of similar rockslide hazards. …”
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