Effects of Pharmacotherapy Training Course on Improving the Drug Prescription Skills of Medical Students: A Pharmacy-based Intervention by Fatemeh Taheri Asl, Mohammadhossein Taherynejad, Maryam Emadzadeh, Mina Akbari Rad, Mohammad Ali Yaghoubi, Amirreza Rostami, Sepideh Hejazi, Mitra Ahadi, Samaneh Sajjadi, Amirali Moodi Ghalibaf, Ali Moradi, Sahar Ravanshad

“…The present findings advocate for the integration of such courses into the medical education curricula, aiming to enhance rational drug prescription practices among future physicians.…”
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Stellar X-Ray Variability and Planetary Evolution in the DS Tucanae System by George W. King, Lía R. Corrales, Vincent Bourrier, Leonardo A. Dos Santos, Lauren Doyle, Baptiste Lavie, Gavin Ramsay, Peter J. Wheatley

“…Improved constraints on the planet's mass in the future would significantly narrow these possibilities. We advocate for further Chandra observations to better constrain the variability of this important system.…”
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Uncovering somatic mosaic variants of PIK3CA-related overgrowth disorders – three cases with different clinical presentations by M. Tooming, M. Tooming, P. Mertsina, T. Kahre, T. Kahre, R. Teek, I. Vainumäe, I. Vainumäe, S. Lilles, S. Lilles, M. H. Wojcik, M. H. Wojcik, M. H. Wojcik, P. Ilves, P. Ilves, K. Õunap, K. Õunap

“…The comprehensive genomic profiling allowed for the meticulous evaluation of potentially pathogenic gene variants in affected individuals and their corresponding tissues.DiscussionOur findings advocate for the adoption of comprehensive genomic profiling in clinical practice to improve the detection and management of PRD. …”
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The evolving landscape of COVID-19: factors associated with in-hospital COVID-19 related mortality during the 2023–2024 phase of JN.1 subvariant dominance by Drieda Zaçe, Albiana Çekrezi, Christopher Jones, Ludovica Ferrari, Giuseppe De Simone, Elisabetta Teti, Vincenzo Malagnino, Marco Iannetta, Loredana Sarmati, Anna Maria Geretti

“…It is imperative to advocate for up-to-date COVID-19 vaccination among older people and other vulnerable groups.…”
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Microplastics in beach sediments, seawater, and common fish in tourist destinations by M. Go, A. Ybanez, A. Ilano, F. Cababat, L. De La Calzada

“…This endeavor is in line with the journal''''''''s objective to oversee the environmental consequences and advocate for improved environmental management strategies. …”
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Effect of technology application in enhancing the weaknesses of market access, financial resources, and supplier resources on the aluminum industry by M.S. Mohamad Salleh, H. Vasudevan

“…The findings of this study contribute to the academic literature by highlighting the importance of technology in facilitating the success of Bumiputera entrepreneurs in the aluminum sector.CONCLUSION: The study empirically confirms and conceptually proves that the policies of industry associations and organizations (“Skim Jaminan Modal Kerja—Bumiputera”, the “Business Act 1956, and the Financial Procedure Act 1957) can advocate for policies that support Bumiputera entrepreneurs in accessing technology and improving their market access, financial resources, and supplier resources. …”
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Soil microbiome interventions for carbon sequestration and climate mitigation by Gwyn A. Beattie, Anna Edlund, Nwadiuto Esiobu, Jack Gilbert, Mette Haubjerg Nicolaisen, Janet K. Jansson, Paul Jensen, Marco Keiluweit, Jay T. Lennon, Jennifer Martiny, Vanessa R. Minnis, Dianne Newman, Raquel Peixoto, Christopher Schadt, Jan Roelof van der Meer

“…ABSTRACT Mitigating climate change in soil ecosystems involves complex plant and microbial processes regulating carbon pools and flows. Here, we advocate for the use of soil microbiome interventions to help increase soil carbon stocks and curb greenhouse gas emissions from managed soils. …”
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Technologies for Interoperable Internet of Medical Things Platforms to Manage Medical Emergencies in Home and Prehospital Care: Scoping Review by Mattias Seth, Hoor Jalo, Åsa Högstedt, Otto Medin, Bengt Arne Sjöqvist, Stefan Candefjord

“…Recognizing the evident benefit of cross-domain interoperability, we advocate a stronger focus on collaborative initiatives and technologies to achieve higher levels of interoperability. …”
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Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study by J S Sons, Z N Mkhize, N C Dlova, C Aldous, P R Bhat, A V Chateau

“…These findings emphasise the urgent need for enhanced patient and healthcare worker education, particularly in primary healthcare settings, to improve adherence to treatment, advocate for prophylactic measures and prevent new cases. …”
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Exploring the Impact of Citric Acid on Mitigating Sweet Potato Soft Rot and Enhancing Postharvest Quality by Yixi Chen, Linjiang Pang, Jiacheng Bai, Wenbao Yu, Yueming Zhu, Melvin Sidikie George, Zunfu Lv, Guoquan Lu

“…In summary, the study demonstrates that 0.5% CAC fortifies the resistance of sweet potato to soft rot by activating defense-related enzymes, suppressing the activity of cell wall-degrading enzymes, and promoting the accumulation of antimicrobial compounds. These results advocate for the utilization of CAC as a postharvest treatment to mitigate the incidence of sweet potato soft rot.…”
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Development of a new data management system for the study of the gut microbiome of children who are small for their gestational age by Felix Manske, Magdalena Durda-Masny, Norbert Grundmann, Jan Mazela, Monika Englert-Golon, Marta Szymankiewicz-Bręborowicz, Joanna Ciomborowska-Basheer, Izabela Makałowska, Anita Szwed, Wojciech Makałowski

“…We used a modular approach for MetagenomicsDB with comprehensive tests verifying the expected behavior and extensively described the underlying rational which allows users to adapt the system to their needs. We advocate the use of MetagenomicsDB as the backend for a graphical web interface. …”
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Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling by Xinghua Yu, Rui Yao, Ge Meng, Lingan Zeng, Leyi Zhou, Yingkang Shen, Amali Upekshika Wijayaraja, Reshmi Hareendra Kariyapperuma, Wentao Xu, Yuxiang Mei, Xinyan Gu, Wen-Long Lei, Pengfei Zhang, Fei Sun

“…These findings offer crucial insights into the potential risks associated with plastic consumption and may advocate for the selection of relatively safe plastic cups for everyday use.…”
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Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

“…The heterogeneity of the included studies points to complex underlying mechanisms, potentially involving modulation of apoptotic pathways and cerebral blood flow.ConclusionThis meta-analysis substantiates the neuroprotective potential of EA in ischemic stroke models, primarily through apoptosis modulation and possibly through improved cerebral perfusion. These findings advocate for the integration of EA into stroke rehabilitation protocols and underscore the need for clinical trials to validate its efficacy in human subjects. …”
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Insights into mungbean defense response to Cercospora leaf spot based on transcriptome analysis by Sukanya Inthaisong, Pakpoom Boonchuen, Tana Jaichopsanthia, Pongpan Songwattana, Apinya Khairum, Witsarut Chueakhunthod, Akkawat Tharapreuksapong, Panlada Tittabutr, Neung Teaumroong, Piyada Alisha Tantasawat

“…Our findings contribute to an understanding of the CLS resistance mechanisms and may advocate the development of more effective disease management approaches.…”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…Following baseline assessment, participants are randomised to receive either minimalist shoes (intervention group) or motion control shoes (control group, given that clinicians typically advocate motion control shoes for patellofemoral pain). …”
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The effect of HLA genotype on disease onset and severity in CTLA-4 insufficiency by Sara Posadas-Cantera, Sara Posadas-Cantera, Noriko Mitsuiki, Florian Emmerich, Virginia Patiño, Hanns-Martin Lorenz, Olaf Neth, Ingunn Dybedal, Kjetil Taskén, Alejandro A. Schäffer, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Laura Gámez-Díaz, Laura Gámez-Díaz

“…Additionally, we found a potential protective association of HLA-DRB1*01:01 with gastrointestinal symptoms.DiscussionEven though, our findings suggest that HLA-A, -B, -C, DRB1, and DQB1 do not contribute to the onset or severity of disease in CTLA-4 insufficiency, certain HLA-alleles may influence the manifestation of specific symptoms. We advocate for further investigation of specific class I and class II HLA alleles as potential disease modifiers in larger clinical cohorts of CTLA-4 insufficiency.…”
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Mpox Preparedness and Response 2024: Position Statement of The Disaster Management Experts Club by Heetaf Aloqaily, Rania Abdurhman Alnafea, Shahad Abdullah Alotaibi, Mohamad Bakir, Sharafaldeen Bin Nafisah, Bandr Mzahim

“…Through this, the Disaster Management Experts Club seeks to advocate: • Augmented surveillance and proactive detection: Surveillance systems are crucial for identifying cases, monitoring transmission dynamics, and detecting potential mutations. …”
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Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

“…Conclusion ACRRGs, particularly MORF4L1, play crucial roles in modulating HCC progression, offering new insights into the molecular mechanisms driving HCC and potential therapeutic targets. Our findings advocate for the inclusion of chromatin remodeling dynamics in the strategic development of precision therapies for HCC.…”
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Impact of Online Interactive Decision Tools on Women’s Decision-Making Regarding Breast Cancer Screening: Systematic Review and Meta-Analysis by Patricia Villain, Laura Downham, Alice Le Bonniec, Charlotte Bauquier, Olena Mandrik, Tom Nadarzynski, Lorie Donelle, Raúl Murillo, Eleni L Tolma, Sonali Johnson, Patricia Soler-Michel, Robert Smith

“…To maximize the effectiveness of e-tools while minimizing potential negative impacts, we advocate for an “on-demand” layered approach to their design.…”
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Artificial intelligence for quantifying immune infiltrates interacting with stroma in colorectal cancer by Jing Yang, Huifen Ye, Xinjuan Fan, Yajun Li, Xiaomei Wu, Minning Zhao, Qingru Hu, Yunrui Ye, Lin Wu, Zhenhui Li, Xueli Zhang, Changhong Liang, Yingyi Wang, Yao Xu, Qian Li, Su Yao, Dingyun You, Ke Zhao, Zaiyi Liu

“…This digital pathology-based finding might advocate change in risk stratification and consequent precision medicine.…”
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