Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

“…Abstract Background Atypical antipsychotics are a common treatment for serious mental illness, but many are associated with adverse effects, including weight gain and cardiovascular issues, and real-world experience may differ from clinical trial data. …”
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The Impact of the COVID-19 Pandemic on Oldest-Old Social Capital and Health and the Role of Digital Inequalities: Longitudinal Cohort Study by Luca Guido Valla, Michele Rossi, Alessandra Gaia, Antonio Guaita, Elena Rolandi

“…ConclusionsThe pandemic had adverse effects on older adults’ health and social capital. …”
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Mechanism of Exogenous Silicon in Enhancing Cold Stress Tolerance in <i>Solanum lycopersicum</i> L. Seedlings: Insights from Resistance and Quality Indicators by Fan Zhang, Yihong Zhao, Yuanbo Zhang, Yu Shi, Leiping Hou, Abid Khan, Ruixing Zhang, Yi Zhang

“…Silicon (Si), recognized as a beneficial element, is posited to mitigate the adverse effects of such stress on plant physiology. This study explores whether exogenous Si fertilizer can effectively alleviate the stress of low temperature and cold damage on tomato plant growth, fruit yield, and quality. …”
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Faktor-Faktor yang Berhubungan dengan Kejadian Pre Eklampsi pada Kehamilan di RSUD Embung Fatimah Kota Batam Tahun 2012 by Dessy Hasmawati

“…This situation will bring adverse effects to the mother and fetus and even death. …”
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Meta-analysis of efficacy and safety of pembrolizumab for the treatment of advanced or recurrent cervical cancer by Xue Zhang, Wen-Jie Yin, Ai-Li Zhang, Xiao-Xiao Zhang, Li-Juan Ding, Jiao Zhang, Shu-Ting He, Jie-Ping Yan

“…Designed to maximise patient benefit and efficiently control adverse effects while maintaining a high standard of living.…”
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Bromfenac in ophthalmic practice by M.L. Maximov, A.A. Zveginceva, I.D. Kanner, N.M. Lapkin

“…Furthermore, the regimen of use (twice daily), no discomfort, and excellent safety profile with minimal adverse effects improve treatment adheren ce. In addition, Bromfenac, a topical anti-inflammatory agent, improves patients’ satisfaction with surgical outcomes since patients achieve maximum possible visual acuity as early as possible.…”
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Effect of Processed Coffee Husk on Feed Intake, Nutrient Digestibility, Body Weight Changes and Economic Feasibility of Bonga Sheep Fed on Natural Pasture Hay as a Basal Diet by Lidya Marew, Fentahun Meheret, Bimrew Asmare

“…Conclusion Therefore, the boiled coffee husk as an alternative feed resource can be replaced by about half of the commercial CM without adverse effects of anti‐nutritional factors and enhance the income of smallholder farmers in the coffee crop‐livestock production system.…”
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Financial crisis and its association with parental stress and children’s mental health in Lebanon by Ramona Nasr, Samantha Abi Saab, Nada Nasr, Chadia Haddad, Eman Swaidan, Sara Abou Ibrahim, Joanne Karam

“…Abstract Background Lebanon has experienced a series of devastating crises that continue to have significant adverse effects on the mental health of parents and their children, especially those who are unemployed, burdened with debt or financial difficulties, and have pre-existing mental health conditions. …”
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InfectA-Chat, an Arabic Large Language Model for Infectious Diseases: Comparative Analysis by Yesim Selcuk, Eunhui Kim, Insung Ahn

“…In this regard, regular monitoring activities play a crucial role in mitigating the adverse effects of diseases on society. To monitor disease trends, various organizations, such as the World Health Organization (WHO) and the European Centre for Disease Prevention and Control (ECDC), collect diverse surveillance data and make them publicly accessible. …”
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Effectiveness of antipsychotic medication in patients with schizophrenia in a real world retrospective observational study in Ethiopia by Mulualem Kelebie, Getasew Kibralew, Gebresilassie Tadesse, Gidey Rtbey, Mekidem aderaw, Wondale Endeshaw, Mitiku Belachew, Mulu Muche, Diemesew Getnet, Setegn Fentahun

“…The antipsychotic drugs are high-affinity antagonists of dopamine D2 receptors that are most effective against psychotic symptoms, but antipsychotic drugs can have side effects that overshadow their advantages, like sedation, extrapyramidal symptoms, and weight gain, which are often experienced as adverse effects. In our country, the relative effectiveness of antipsychotic medication as well as their tolerance in schizophrenia patients is not fully addressed. …”
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The Mechanisms of Guaranteeing the Right to Clean Air in Iran and International Documents by Fatemeh Hamidi, Maryam Afshari, Ali Mashhadi

“…Introduction: Air pollution is a major global environmental problem that has various adverse effects on health and the environment. Countries have come to the conclusion that the fight against this problem will only be possible through international cooperation. …”
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Risk barriers and sustainability in payment for ecosystem service implementation in smallholder forestry by A. Ibrahim, S. Withaningsih, R. Kinseng, Parikesit ., D. Muhamad

“…The success of programs is further endangered by subpar program design, insufficient conservation measures, and the adverse effects of climate change. Ultimately, comprehending and addressing these obstacles is essential in order to fully realize the benefits of payment for ecosystem services in agroforestry.bComprehensive strategies, including policy support, stakeholder engagement, and fair compensation coupled with collaborative efforts from governments, non-government organizations, local communities, and private enterprises are essential. …”
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“I believe it when there is an expert next to me:” a qualitative analysis on the perceptions and experiences of pregnant women to self-monitor blood pressure in Lombok, Indonesia... by Tigest Tamrat, Yuni Dwi Setiyawati, Maria Barreix, Nya’Jeumpa Madani, Antoine Geissbühler, Anuraj H. Shankar, Ozge Tuncalp

“…Abstract Background Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal deaths and require close monitoring of blood pressure (BP) to mitigate potential adverse effects. The World Health Organization (WHO) recommends self-monitoring of blood pressure (SMBP) among women with HDP; however, there is limited research on its acceptability and feasibility in low- and middle-income contexts. …”
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Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma by Malcolm K Brenner, Challice Bonifant, Norihiro Watanabe, Mary K McKenna, Daniel Brenner, Ada Ozcan, Maureen Legendre, Dafydd G Thomas, Christopher Ashwood, Richard D Cummings, David M Markovitz

“…H84T CAR T cells exhibited improved T-cell infiltration in multicellular spheroids and had potent antitumor effects in the xenograft models. We observed no adverse effects against normal tissues.Conclusions T cells expressing H84T CAR target malignant cells and their stroma in PDAC tumor models. …”
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Comparative Analysis of Multiple Hydrological Models in Assessing Climate Change Impacts on the Mille Watershed, Awash Basin, Ethiopia by Asmare Belay Nigussie, Mihiretie Ayana, Dessalegn Worku Ayalew, Gerawork Feleke, Asnake Enawgaw Amognehegn, Anteneh Yayeh Adamu, Andualem Endalew, Tewodrose Desale Meselaw, Shankar Karuppannan

“…These measures are crucial for mitigating the adverse effects of climate change and ensuring the resilience of the region’s water resources.…”
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Effect of intravitreal injections on the progression and prognosis of primary open-angle glaucoma by A.B. Movsisyan, N.G. Glazko, A.Yu. Brezhnev, A.V. Kuroyedov

“…Considering a lack of relevant data on long-term adverse effects on IOP level and cup area, and improvement of visual functions, IVIs are regarded as a safe treatment modality in patients with primary open-angle glaucoma (POAG) and ocular comorbidities that require IVIs.…”
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Effective cancer immunotherapy combining mRNA-encoded bispecific antibodies that induce polyclonal T cell engagement and PD-L1-dependent 4-1BB costimulation by Oana Hangiu, Oana Hangiu, Oana Hangiu, Rocío Navarro, Susana Frago, Laura Rubio-Pérez, Laura Rubio-Pérez, Laura Rubio-Pérez, Antonio Tapia-Galisteo, Antonio Tapia-Galisteo, Antonio Tapia-Galisteo, Laura Díez-Alonso, Laura Díez-Alonso, Laura Díez-Alonso, Marina Gómez-Rosel, Marina Gómez-Rosel, Marina Gómez-Rosel, Noelia Silva-Pilipich, Noelia Silva-Pilipich, Lucía Vanrell, Cristian Smerdou, Cristian Smerdou, Kenneth A. Howard, Laura Sanz, Luis Álvarez-Vallina, Luis Álvarez-Vallina, Luis Álvarez-Vallina, Marta Compte

“…Bispecific T cell-engaging (TCE) antibodies are an effective way to provide tumor-specific T cell receptor-mediated signaling to tumor-infiltrating lymphocytes. mRNA-based delivery of bispecific antibodies, offer a novel approach to enhance tumor-specific immune responses while minimizing adverse effects.MethodsTwo bispecific antibodies were generated: the EGFR x CD3 TCE antibody (LiTE) and the PD-L1 x 4-1BB costimulatory antibody (LiTCo), which was further fused to a high FcRn albumin variant (Albu-LiTCo). …”
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Effects of dietary amylose/amylopectin ratio on antioxidant ability and amino metabolism in the liver of weaned piglets undergoing feed transition and challenged with lipopolysacch... by Can Yang, Can Yang, Xiaowu Tang, Min Wang, Han Yang, Huansheng Yang, Yancan Wang, Yulong Yin, Yulong Yin

“…After LPS stress, colonic skatole concentration increased in DAR 0.40, 0.80 but decreased in other groups (p &lt; 0.05). In conclusion, adverse effects of the LPS challenge could be reversed by feeding weaned piglets with low or high DAR diet through regulating amino metabolism and antioxidant function.…”
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Feasibility of trancutaneous auricular vagus nerve stimulation in Black and Hispanic/Latino people with peripheral neuropathy by Marlon L. Wong, Eva Widerström-Noga, Jessica L. Bolanos, Gabriel Gonzalez, Frank J. Penedo, Peter J. Hosein, Melissa M. Tovin, Juan P. Gonzalez, Lisa M. McTeague

“…The pilot RCT enrolled 28 participants, achieving a 42% recruitment rate and 86% retention. taVNS was well tolerated, with no significant adverse effects. Preliminary data indicated a decrease in neuropathic symptoms and an increased heart rate variability (HRV) during active taVNS, suggesting autonomic modulation. …”
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Supporting rotational grazing systems with virtual fencing: paddock transitions, beef heifer performance, and stress response by N.A. Grinnell, D. Hamidi, M. Komainda, F. Riesch, J. Horn, I. Traulsen, R. Palme, J. Isselstein

“…While previous studies have largely dispelled concerns about adverse effects on cattle behaviour associated with the use of VF collars, there is limited knowledge regarding the impacts on animal physiology, particularly in rotational stocking systems. …”
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