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  1. 1801

    Capsaicin Modulates Ruminal Fermentation and Bacterial Communities in Beef Cattle with High-Grain Diet-Induced Subacute Ruminal Acidosis by Wei You, Haijian Cheng, Xin Hu, Enliang Song, Fugui Jiang

    Published 2025-01-01
    “…In summary, these results suggest that dietary capsaicin supplementation can limit the adverse effects of SARA through the modulation of bacterial communities within the rumen, thus altering ruminal fermentation in beef cattle.…”
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  2. 1802

    Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report by Zhao-Xia Ma, Xing-Fei Wu, Li Cao, Cheng-Yan Jiao, Dai-Ping Ma, Yun-Hui Zhao, Zhi-Xing Yang, Min Hu, Min Hu

    Published 2025-01-01
    “…In vitro experiments showed that rFib could significantly inhibit the proliferation of T lymphocytes after PHA stimulation. No adverse effects were associated with the use of rFib in the volunteer during the clinical trial.SummaryThe results of this clinical trial indicate that intravenous injections of autologous rFib are both safe and effective for treating SS. …”
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  3. 1803

    Maximizing the potential of water buffalo milkability: best practices and lessons learned by Carlo Boselli, Antonio Borghese

    Published 2023-11-01
    “…The differences were the following: better pre-stimulation allowing a positive endogenous release of oxytocin, with reduced lag time; independent milk ejection for each teat, with optimal milking of all quarters, with the reduction of BT; improvement of milking hygiene during milking, limiting the incidence of mastitis and with a low value of somatic cell score; adverse effects due to failed or incomplete milking (17% of the total milkings), limiting the potential capacity and efficiency of AMS; frequent leakage of airflow, which could cause alteration of milk composition. …”
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  4. 1804

    Antidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients by Genet Alem Geberemeskel, Yared Godefa Debebe, Nigisty Abraha Nguse

    Published 2019-01-01
    “…The present study showed that the administration of Trigonella foenum-graecum seed powder solution had pronounced effects in improving lipid metabolism in type II diabetic patients with no adverse effects. Therefore, Trigonella foenum-graecum seed may provide new alternatives for the clinical management of type II diabetes.…”
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  5. 1805

    Multilevel analysis of prevalence and determinants of diarrhea among under-five children in Somalia: insights from the Somalia demographic and health survey 2020 by Hamse Arab Ali, Abdulkadir Mohamed Nuh, Hamse Adam Abdi, Abdisalam Hassan Muse

    Published 2025-01-01
    “…Moreover, targeted economic support, health care programs for older mothers are essential to mitigate the adverse effects of socioeconomic factors on child health, ultimately leading to a substantial reduction in diarrheal diseases among young children.…”
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  6. 1806

    All extern? Exploring the Impact of Social Media and Physical Activity on Adolescents’ Body Image and Interoception by Moritz Peter Engel, Mirko Schmidt

    Published 2025-01-01
    “…., 2023), positioning it as a promising candidate for mitigating potential adverse effects of social media use. Therefore, this study aims to examine the effects of both social media exposure and physical activity on adolescents’ body image and interoception. …”
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  7. 1807

    Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

    Published 2025-02-01
    “…No life-threatening AEs were reported.ConclusionThe HAIC-L-P regimen correlated with enhanced tumor responses and prolonged survival, alongside manageable adverse effects, indicating its potential as a viable therapeutic strategy for individuals afflicted with uHCC.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024594109.…”
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  8. 1808

    Lipid-encapsulated gold nanoparticles: an advanced strategy for attenuating the inflammatory response in SARS-CoV-2 infection by Sanjeevram Dhandapani, Yujeong Ha, Rongbo Wang, Tae Woo Kwon, Ik-Hyun Cho, Yeon-Ju Kim

    Published 2025-01-01
    “…Biochemical analysis at various oral administration concentrations demonstrated that KGS-NE had no adverse effects on the kidney and liver. Conclusions Our findings strongly suggest that oral administering KGS-NE in mice and Syrian hamster models has the potential to effectively mitigate lung inflammation against coronavirus. …”
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  9. 1809

    Exogenous 2,4-Epibrassinolide Alleviates Alkaline Stress in Cucumber by Modulating Photosynthetic Performance by Wenjing Nie, Qinghai He, Jinzhao Ma, Hongen Guo, Qinghua Shi

    Published 2024-12-01
    “…In summary, EBR markedly mitigated the adverse effects of alkaline stress on cucumber leaf photosynthesis by stabilizing the photosynthetic electron transport system, accelerating photosynthetic electron transport, and promoting the Calvin cycle. …”
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  10. 1810
  11. 1811

    Concurrent versus sequential immunotherapy with chemoradiotherapy for unresectable stage III non-small-cell lung cancer: a retrospective study by Zhou Meng-Xi, Fan Wen-Jie, Zhang Ning, Zhu Li-Yang, Wang Hong-Yan

    Published 2025-01-01
    “…Treatment-related adverse effects were assessed and graded.ResultsA total of 98 patients with unresectable stage III NSCLC treated with chemoradiotherapy and ICIs were included. …”
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  12. 1812

    Scopoletin as a cardioprotective agent against cisplatin-induced oxidative stress and inflammation by Esam Qnais, Omar Gammoh, Yousra Bsieso, Mohammad Alqudah, Mohammad Wedyan, Sara Altaber, Alaa A.A. Aljabali, Abdelrahim Alqudah, Taher Hatahet

    Published 2025-02-01
    “…Conclusion: The findings suggest scopoletin's potential as an adjunctive therapy in cancer treatment to mitigate CP's adverse effects, warranting further clinical investigation.…”
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  13. 1813

    Bony ankylosis adversely affects postoperative hip function in patients with ankylosing spondylitis undergoing total hip arthroplasty: a retrospective cohort study of 319 consecuti... by Liangliang Li, Jun Fu, Chi Xu, Ming Ni, Wei Chai, Libo Hao, Yonggang Zhou, Jiying Chen

    Published 2025-02-01
    “…Bony ankylosis has adverse effects on postoperative hip function in patients with AS, suggesting that performing THA before ankylosis occurs can lead to better subjective outcomes and better postoperative hip function. …”
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  14. 1814

    Bioequivalence study of fluticasone propionate nebuliser suspensions in healthy Chinese subjects by Feng Cheng, Tao Shen, Fucheng Zhang, Chenghao Lei, Ye Zhu, GuoJun Luo, Dawei Xiao

    Published 2025-01-01
    “…Fluticasone propionate nebuliser suspensions is an inhaled corticosteroid with the low systemic bioavailability which provides a low risk (benefit outcome without the adverse effects that accompany systemically administered corticosteroids), referred as a first-line preventive agent for patients with persistent asthma. …”
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  15. 1815

    Replacing rice straw with peanut vine and Broussonetia papyrifera silage in beef cattle feed reduced the use of soybean meal by Xin Yi, Yueming Li, Yue Liu, Minzhe Zhang, Zhenming Zhou, Qingxiang Meng, Hao Wu

    Published 2025-03-01
    “…In conclusion, replacing rice straw with PEV and BPS reduced the use of soybean meal but had no adverse effects on growth performance. BPS affected the amino acid metabolism of bulls, thus decreasing feed intake and increasing the lysine content in meat. …”
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  16. 1816

    Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

    Published 2025-01-01
    “…Serum insulin was an important mediator in the adverse effects of glyphosate on CVH with an 18.73 % mediation proportion. …”
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  17. 1817

    Oxaliplatin-Loaded Chitosan Nanoparticles Decorated with Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment by Khadijeh Falahzadeh, Fariba Esmaeili, Leila Nematollahi, Elham Bayat, Mehdi Khoobi, Mohammadali Mazloomi, Masumeh Jalalvand, Reza Faridi Majidi, Babak Negahdari

    Published 2024-09-01
    “…Engineeredbiomolecules can be used as a targeted tool to deliver drugs directly to tumors that reduce the adverse effects of conventionaltreatments. We aimed to prepare non-targeted oxaliplatin-loaded chitosan nanoparticles (OXPT-CS NPs) and targetedOXPT-CS NPs decorated with cetuximab single-chain variable fragment (scFv) to send both NPs to epidermal growth factorreceptor (EGFR) overexpressing HCT 116 cells, a human colorectal carcinoma cell line, for comparing their cytotoxicity.Materials and Methods: In this experimental study, OXPT-CS NPs were synthesized using a fluid system. …”
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  18. 1818

    Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers by Pragya Sinha, Faye M Johnson, Soma Ghosh, Jagannadha K Sastry, Madison P O'Hara, Tuhina Mazumdar, Lacin Yapindi

    Published 2025-01-01
    “…Standard-of-care chemotherapy, radiotherapy, and immune checkpoint inhibitors (ICIs) are associated with adverse effects and limited responses in patients with HPV-driven cancers. …”
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  19. 1819

    Study on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data by Na Wang, Mengran Chang, Shidong Liu, Bing Chen

    Published 2025-01-01
    “…However, previous studies have largely focused on teenage girls, perimenopausal women, or women during pregnancy and the postpartum period, neglecting the adverse effects of major diseases, which is detrimental to enhancing the psychological well-being of women with cancer.ObjectiveBased on cancer impacts, this study aims to clarify the depressive state, development trends, and influencing factors in Chinese women with cancer, a group particularly susceptible to depression, to provide decision-making references for improving their psychological well-being.MethodsUsing follow-up panel data from five waves of China Health and Retirement Longitudinal Study (CHARLS), Chinese women with cancer who had complete observed values were selected as research subjects. …”
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  20. 1820

    Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis by Ziying Wu, Xiang Ding, Guanghua Lei, Chao Zeng, Jie Wei, Jiatian Li, Hui Li, Tuo Yang, Yang Cui, Yilin Xiong, Yilun Wang, Dongxing Xie

    Published 2018-12-01
    “…Objective To investigate the efficacy and safety of the pulsed electromagnetic field (PEMF) therapy in treating osteoarthritis (OA).Design Meta-analysis.Data sources PubMed, Embase, the Cochrane Library and Web of Science were searched through 13 October 2017.Eligibility criteria for selecting studies Randomised controlled trials compared the efficacy of PEMF therapy with sham control in patients with OA.Data extraction and synthesis Pain, function, adverse effects and characteristics of participants were extracted. …”
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