Zebrafish Embryo Toxicity of a Binary Mixture of Pyrethroid Insecticides: d-Tetramethrin and Cyphenothrin by Janthri C. Mendis, Thejani K. Tennakoon, Chanika D. Jayasinghe

“…Both d-tetramethrin and cyphenothrin are synthetic pyrethroids that are known to have adverse effects on non-mammalian organisms such as fish. …”
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Evaluation of the therapeutic efficacy of high-intensity focused ultrasound ablation combined with different drugs in the treatment of adenomyosis by Yu Dai, Ling Liu, Guiyuan Yu, Yan Peng, Na Chen, Jiahong Gao, Qiuling Shi, Ping Jin

“…Furthermore, patients in Group B had a greater uterine volume reduction at 24 months after HIFU than that of patients in Group A [51.00 (27.00, 62.00) vs. 30.00 (17.00, 42.75, p = 0.02)]. However, the adverse effects in Group A were lower than those in Group B [7 (15.79) vs. 35 (46.05), p < 0.01]. …”
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Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation by Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun

“…Group C experienced significantly less injection pain (p = 0.001), although the incidence of other adverse effects was not statistically different between groups (p > 0.05). …”
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Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs by Abubakar Danmaigoro, Gayathri Thevi Selvarajah, Mohd Hezmee Mohd Noor, Rozi Mahmud, Md Zuki Abu Bakar

“…This finding offers opportunity to dogs with cancer that might require long-term administration of DOX without adverse effects.…”
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HACE1 protects against myocardial ischemia–reperfusion injury via inhibition of mitochondrial fission in mice by Bang-Xia Liu, Juan Zheng, Zhan-Wei Tang, Lei Gao, Meng Wang, Ying Sun, Chen Chen, Heng-Chen Yao

“…On the other hand, HACE1 knockout further reduced superoxide dismutase (SOD) activity in the myocardium(P < 0.05), further supporting the findings. However, the adverse effects were almost completely eliminated by pharmacological blockade of the dynamin-related protein 1 (Drp1) inhibitor, Mdivi-1, which inhibits mitochondrial fission during cardiac I/R(P < 0.05). …”
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Efficacy and safety of intravenous ferric carboxymaltose in the treatment of Restless Legs Syndrome: a systematic review and meta-analysis by Ayesha Khan, Harsh Kumar, Kuldeep Dalpat Rai, Anzel Saeed, Jawad Ishtiaq, Muhammad Tanveer Alam, Sakshi Chawla, Md Ariful Haque, Md Ariful Haque

“…The treatment appears generally well-tolerated, with adverse effects being manageable. However, further long-term studies are needed to fully assess the safety profile and confirm sustained symptom improvement in a broader population.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42024585233.…”
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Early embryonic thermal programming and post-hatch flavonoid (Scutellaria baicalensis) supplementation enhanced immune response markers in broiler chickens by Sadid Al Amaz, Md Ahosanul Haque Shahid, Rajesh Jha, Birendra Mishra

“…Early embryonic Thermal Manipulation (TM) has been suggested as an effective and sustainable way to mitigate the adverse effects of HS. This study investigated how these interventions influenced the immune status of broiler chickens exposed to HS.MethodsCobb 500 fertile eggs (n = 600) were incubated according to guidelines. …”
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Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…We synthesized data from eligible studies using relative risk or mean difference, and analyzed differences in hemodynamic stability and adverse effects between the two drugs. Data extraction and quality assessment were performed independently by two researchers.ResultsEight randomized controlled trials involving 571 participants were included. …”
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Evaluating the influence of anti-PD-1 immunotherapy combined with IMRT on thyroid dysfunction in nasopharyngeal carcinoma by Liqianqi Chen, Zihuang Li, Xianming Li, Shihai Wu, Long Gong, Gang Xu, Shanyi Chen, Yucong Zhang

“…However, its potent anti-tumor effects can also attack normal tissues and organs, leading to immune-related adverse effects (irAE), with the thyroid being one of the most commonly affected organs. …”
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Glutamine-glutamate centered metabolism as the potential therapeutic target against Japanese encephalitis virus-induced encephalitis by Mengyuan Li, Hang Yuan, Xiaofei Yang, Yingfeng Lei, Jianqi Lian

“…In addition, viral infection restrained the utilization of glutamine via the glutamate-α-ketoglutaric acid axis in neurons, thus avoiding the adverse effects of glutamine oxidation on viral propagation. …”
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The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: A prospective, randomized study by Yavuz Demiraran, Esin Korkut, Ali Tamer, Ilknur Yorulmaz, Buket Kocaman, Gulbin Sezen, Yusuf Akcan

“…In the midazolam group, the number of patients who had adverse effects was higher than the dexmedetomidine group ( < 0.05). …”
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Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial by Qi Liu, Min Zhang, Liyuan Tao, Chunli Song, Haiyan Li, Gengyu Han, Runting Li, Dongwei Fan, Guohong Du, Dongyang Liu

“…A meta-analysis reported that the incidence of APR was 49.4% among patients with OP who received ZA for the first time and that 30% of patients with these adverse effects refused treatment in the following year. …”
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The Association between Short-Term PM2.5 Exposure and Long COVID on the Respiratory System by Pornpun Sakunkoo, Chananya Jirapornkul, Naowarat Maneenin, Yuparat Limmongkon, Jetnapis Rayubkul, Kittipong Sornlorm, Rajitra Nawawonganun

“…During the COVID-19 pandemic, several countries, including Thailand, encountered the issue of PM2.5 pollution, which has had adverse effects on human health. This study was to evaluate the impact of short-term exposure to PM2.5 on the respiratory system and its correlation with the prevalence of Long COVID, while also examining the relevant factors, particularly the presence of PM2.5 exposure. …”
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Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita by Sana Alam, Gulnaz Afzal, Riaz Hussain, Hafiz Muhammad Ali, Amtul Sami, Rabbiah Manzoor Malik, Raheela Jabeen, Farid Shokry Ataya, Kun Li

“…Abstract Thiram is a widely used fungicide in agricultural practices as spraying on crops and grains storage but its potential adverse effects on non-target aquatic organisms have raised serious concerns. …”
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Prediction and Impact of Supersaturated Total Dissolved Gas in Flood Discharge of Flood Control Reservoirs in Southwest Mountain Areas: A Case Study in Jiangjiakou Reservoir by ZHANG Zhihao, ZHANG Peng, LIANG Ruifeng, WANG Qingfeng, WANG Yuanming, LI Kefeng

“…With the transportation and dissipation of TDG under the dam, the TDG concentration of each river section under each condition is lower than 115%, except the river reach between Jiangjiakou dam site and river section downstream of the dam with a distance of 2.7 km (the surface spillway to discharge the flood once in five years) and the river reach between dam site and Tongjiang river confluence (the bottom outlet discharge cavity to discharge the flood once every five years); ② In all four flood discharge scenarios, supersaturated TDG will not have adverse effects on the silver carp; and ③ the hydrodynamics shows that the water depths of the river reaches downstream of dam meet the compensation water depth for Rock carp under all scenarios, and this species will not be affected by supersaturated TDG after using the compensation water depth. …”
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Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungi Alternaria alternata BRN05 isolated from seeds of Swietenia mac... by Piyush Kumar, Sai Anand Kannakazhi Kantari, Ranendra Pratap Biswal, Prasanth Ghanta, Malleswara Dharanikota

“…There is a growing demand for new diabetes drugs with fewer side effects to replace current medications known for their adverse effects. Inhibition of α-glucosidase responsible for postprandial hyperglycemia among diabetes patients is a promising strategy for managing the disease. …”
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Factors Influencing the Activities of Daily Living of Patients with Spinal Cord Injury in Community by Yiting XIE, Cai JIANG, Guanli XIE, Jia HUANG, Jingsong WU, Jing TAO

“…Early attention to the key factors affecting the activities of daily living of patients with spinal cord injury in the community can effectively prevent its adverse effects and improve the patient's ability to perform activities in daily life, thereby improving the quality of life of patients with spinal cord injury in the community.…”
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Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement by Anas H. A. Abu-Humaidan, Fatima M. Ahmad, Dima Awajan, Raba’a F. Jarrar, Nader Alaridah

“…Participants’ demographic data, type of vaccine, date of vaccination, as well as adverse effects of the vaccine were recorded. The serum samples were incubated with S protein RBD-coated plates. …”
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Optimizing Cucumber (<i>Cucumis sativus</i> L.) Fruit Metabolomics Under Elevated CO₂ and High-Temperature Stress in the Greenhouse by Xian Du, Yang Song, Lu Pan, Shimao Cui

“…This study aims to elucidate the response mechanisms of cucumber fruit metabolomics under elevated CO₂ and high-temperature stress while also exploring the potential benefits of elevated CO₂ in mitigating the adverse effects of high temperatures. The fruits of the experimental material cucumber (<i>Cucumis sativus</i> L., ’Jinyou 35’) were grown under soil conditions in the greenhouse. …”
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Biodistribution of a Mitochondrial Metabolic Tracer, [18F]F-AraG, in Healthy Volunteers by Jelena Levi, Heying Duan, Shahriar Yaghoubi, Juliet Packiasamy, Lyna Huynh, Tina Lam, Faiq Shaikh, Deepak Behera, Hong Song, Joseph Blecha, Salma Jivan, Youngho Seo, Henry F. VanBrocklin

“…PET/MR examination was well tolerated, and no adverse effects to the administration of [18F]F-AraG were noted by the study participants. …”
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