Cryoablation for advanced non-small cell lung cancer: a protocol for a systematic review by Dan Wang, Yu Chen, Hua Duan, Shu-Yue Zheng, Chufan Luo, Xueni Fang, Haoyue Pang, Man Wang, Tian Zhou, Quanwang Li, Kaiwen Hu

“…The secondary outcomes will be adverse effects, health-related quality of life, changes of immune indicators and surrogate outcomes (disease control rate, progression-free survival and survival rate).Ethics and dissemination Ethics approval is not required, as this study will not involve patients. …”
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Comparative efficacy of chemical peels and laser treatments in melasma: a meta-analysis of randomized controlled trials by Ingyu Lee, SeoWon Kang, JinHan Lee, Hyungin Cho, Ki Won Lee, Dongkeun Lim

“…Chemical peels, though slower, are safer for patients prone to adverse effects. Combination therapies and maintenance strategies may improve long-term outcomes in melasma…”
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Metal Biomonitoring Through Arboreal Species in Riparian Ecosystems: <i>Pithecellobium dulce</i> as a Bioindicator Species by Sayuri Hernández-Maravilla, María Luisa Castrejón-Godínez, Efraín Tovar-Sánchez, Hugo Albeiro Saldarriaga-Noreña, Alexis Rodríguez, Marcos Eduardo Rosas-Ramírez, Patricia Mussali-Galante

“…In riparian ecosystems, metal pollution generates adverse effects on organisms and reduces water quality. …”
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Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway by Yongnan Piao, Nuoya Wang, Mingji Jin, Jianyu Piao, Mingfeng Han, Zifei Wang, Chunhua Quan, Jishan Yin, Zhonggao Gao, Wenxiang Cui, Shuangqing Wang, Xiuquan Quan

“…In addition, the combination of OME and FD-L did not significantly affect the therapeutic efficacy of OME, but reduced its adverse effects. Ultimately, FD presentation had a pro-healing effect on the ethanol-induced gastric ulcer model. …”
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Deciphering the potential of plant metabolites as insecticides against melon fly (Zeugodacus cucurbitae): Exposing control alternatives to assure food security by Zinat Jahan Chowdhury, Anik Banik, Tanjin Barketullah Robin, Mohammed Rashed Chowdhury

“…The leading compounds showed no adverse effects that could diminish their insecticidal potential. …”
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Associations between environmental glyphosate exposure and glucose homeostasis indices in US general adults: a national population-based cross-sectional study by Xiaobing Feng, Min Wang, Yuji Wang, Ruyi Liang, Chunxiang Yan

“…Abstract As glyphosate’s application becomes increasingly widespread across the globe, its potential adverse effects on humans have garnered growing concerns. …”
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pACP-HybDeep: predicting anticancer peptides using binary tree growth based transformer and structural feature encoding with deep-hybrid learning by Shahid, Maqsood Hayat, Wajdi Alghamdi, Shahid Akbar, Ali Raza, Rabiah Abdul Kadir, Mahidur R. Sarker

“…Recently the high selectivity of peptides has garnered significant attention from scientists due to their reliable targeted actions and minimal adverse effects. Furthermore, keeping the significant outcomes of the existing computational models, we propose a highly reliable and effective model namely, pACP-HybDeep for the accurate prediction of anticancer peptides. …”
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Enhanced UV-B photoprotection activity of carotenoids from the novel Arthrobacter sp. strain LAPM80 isolated from King George Island, Antarctica by Beatriz Vivian Paredes Contreras, Alane Beatriz Vermelho, Livia Casanova, Claudia de Alencar Santos Lage, Caren Leite Spindola Vilela, Veronica da Silva Cardoso, Luis William Pacheco Arge, Janine Simas Cardoso-Rurr, Sulamita Santos Correa, Felipe Raposo Passos De Mansoldo, Maria Cristina Pinheiro Pereira Reis-Mansur, Eikon Alves da Silva, Júnia Schultz, Alexandre Soares Rosado

“…Also, there is a growing demand for natural and environmentally friendly photoprotectors, such as microbial-based products, in opposition to synthetic photoprotective agents with known adverse effects.In this study, we assessed the carotenoid-producing abilities of Actinomycetota strains from Antarctic Peninsula soils and the photoprotective carotenoid action on UV irradiation resistance. …”
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Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

“…Nowadays, targeted therapies remain the gold standard for many patients, but still they suffer from many adverse effects, including unexpected toxicity and intrinsic acquired resistance mutations, which lead to relapse. …”
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Amphotericin B Encapsulation in Polymeric Nanoparticles: Toxicity Insights via Cells and Zebrafish Embryo Testing by Magno Maciel-Magalhães, Renata Jurema Medeiros, Nayara Cecília do Couto Guedes, Thais Morais de Brito, Gabriele Fátima de Souza, Beatriz Rodrigues Canabarro, Fausto Klabund Ferraris, Fábio Coelho Amendoeira, Helvécio Vinicius Antunes Rocha, Beatriz Ferreira de Carvalho Patricio, Isabella Fernandes Delgado

“…However, its clinical application is constrained because of its poor oral bioavailability and adverse effects, prompting the investigation of alternative drug delivery systems. …”
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Disparities in response to mRNA SARS-CoV-2 vaccines according to sex and age: A systematic review by Michelle Bachmann, Nejla Gültekin, Zeno Stanga, Jan S. Fehr, Ismail I. Ülgür, Patricia Schlagenhauf

“…Comparing the sexes reveals that higher immunological responses were induced in females, and mild to moderate adverse effects (such as injection site discomfort, exhaustion, and headaches) were also more frequently reported in women. …”
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Comparison of Ticagrelor and Clopidogrel in Elective Coronary Stenting: A Double Blind Randomized Clinical Trial by Mohammadjavad Mehdizadeh Parizi, Reza Golchin Vafa, Amin Ahmadi, Reza Heydarzade, Mehrdad Sadeghi, Amin Khademolhossseini, Farhang Amiri, Soroush Khoshnood Mansorkhani, Ali Tavan, Nazanin Hosseini, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri

“…., clopidogrel and ticagrelor) and aspirin is recommended for at least one year after percutaneous coronary intervention (PCI) to prevent further myocardial infarction and stent thrombosis as the major adverse effects of PCI. Methods. This randomized clinical trial was conducted from October 2022 to March 2023. …”
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Apelinergic System Affects Electrocardiographic Abnormalities Induced by Doxorubicin by Kasper Buczma, Hubert Borzuta, Katarzyna Kamińska, Dorota Sztechman, Katarzyna Matusik, Jan Pawlonka, Michał Kowara, Barbara Buchalska, Agnieszka Cudnoch-Jędrzejewska

“…<b>Background/Objectives</b>: Anthracyclines remain a pivotal element of numerous tumor management regimens; however, their utilization is associated with a range of adverse effects, the most significant of which is cardiotoxicity. …”
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INTRAPERITONEAL AEROSOL CHEMOTHERAPY UNDER PRESSURE (IACUP) – AN INNOVATIVE METHOD OF TREATMENT OF PATIENTS WITH PERITONEAL CARCINOMATOSIS by A. D. Kaprin, V. M. Khomyakov, A. B. Ryabov, L. V. Bolotina, A. V. Ivanov, A. B. Utkina, V. V. Cheremisov, I. V. Kolobaev, A. V. Chaika, D. D. Sobolev, L. A. Koroleva

“…In the framework of the safety assessment of IACUP there were 3 cases of adverse effects. Two patients (7,4%) noted nausea for the first 2 days after running the session of IACUP. …”
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Neethling Strain-Based Homologous Live Attenuated LSDV Vaccines Provide Protection Against Infection with a Clade 2.5 Recombinant LSDV Strain by Wannes Philips, Andy Haegeman, Nina Krešić, Laurent Mostin, Nick De Regge

“…Results: Only limited adverse effects were observed after vaccination, and all vaccinated animals seroconverted and showed an LSDV-specific cellular immune response after vaccination. …”
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Fractionated radiotherapy initiated at the early stage of bone metastasis is effective to prolong survival in mouse model by Yun Zhang, Zhunyi Gao, Ziwei Qi, Jiahe Xu, Jiao Xue, Lujie Xiong, Junhui Wang, Yuhui Huang, Songbing Qin

“…Conversely, fractionated RT mitigated tumor growth in bone metastases with fewer adverse effects. Fractioned RT initiated at the early stage of bone metastasis effectively inhibited tumor growth in the bone, suppressed secondary lung metastases, and prolonged mouse survival. …”
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Effects of Melatonin and Epiphyseal Proteins on Fluoride-Induced Adverse Changes in Antioxidant Status of Heart, Liver, and Kidney of Rats by Vijay K. Bharti, R. S. Srivastava, H. Kumar, S. Bag, A. C. Majumdar, G. Singh, S. R. Pandi-Perumal, Gregory M. Brown

“…The present data suggest that F can induce oxidative stress in liver, heart, and kidney of female rats which may be a mechanism in F toxicity and these adverse effects can be ameliorated by buffalo (Bubalus bubalis) epiphyseal proteins and melatonin by upregulation of antioxidant defense system of heart, liver, and kidney of rats.…”
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Toxicity of Low-dose Graphene Oxide Nanoparticles in an in-vivo Wild Type of Caenorhabditis elegans Model by Ming-Hsien Tsai, How-Ran Chao, Jheng-Jie Jiang, Yu-Hsieh Su, Mariene-syne P. Cortez, Lemmuel L. Tayo, I-Cheng Lu, Hao Hsieh, Chih-Chung Lin, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang, Wen-Li Hsu

“…In this study, the environmental levels of GO NPs are addressed to examine whether GO leads to adverse effects on an in-vivo model of Caenorhabditis elegans (C. elegans). …”
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Exploratory analysis of potential toxic elements in Moroccan couscous and health risk evaluation utilizing ICP-OES by Othmane Hammani, Najlae El-Otmani, Omar Ben Lenda, Hamza El Azhari, Abderrazak Rfaki, Naima Lahlouhi, Youssef Mourad, Abdelaziz Abdallaoui

“…However, these grains are susceptible to the accumulation of trace elements that can have adverse effects on human health. In order to address this concern, our exploratory study assessed the contamination levels in couscous samples available in Morocco in 2023, focusing on lead (Pb) and cadmium (Cd) due to their severe health impacts even at low concentrations, as noted by the WHO. …”
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Bio-concentration of hazardous metals in migrant shorebirds in a key conservation reserve and adjoining areas on the west coast of India by K.M. Aarif, K.A. Rubeena, Aymen Nefla, Zuzana Musilova, Petr Musil, Sabir Bin Muzaffar

“…Heavy metals have known adverse effects on shorebirds. Our study shows that reducing pollution and protecting community reserves alongside their surrounding habitats are crucial to combat biodiversity loss and maintain diversity in these areas.…”
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