The Role of Yersinia enterocolitica O:3 Lipopolysaccharide in Collagen-Induced Arthritis by Katarzyna Kasperkiewicz, Anna S. Świerzko, Marta Przybyła, Janusz Szemraj, Jarosław Barski, Mikael Skurnik, Andrzej Kałużyński, Maciej Cedzyński

“…Our data did not suggest no greater impact Y. enterocolitica O:3 on the development or severity of arthropathy related to anticollagen antibody-induced arthritis in mice, although its interaction with MBL-C and subsequent complement activation may contribute to some adverse effects.…”
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1-Methylcyclopropene Delays Browning and Maintains Aroma in Fresh-Cut Nectarines by Rui Zhang, Ze Miao, Shuang Xie, Jiao Li, Sheng Tao, Yuqian Jiang, Lingling Pang, Lihua Duan, Xihong Li

“…The color and aroma of nectarines experience adverse effects from cutting, resulting in the fast senescence of fruit tissue. …”
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Impact of 17-alpha ethinyl estradiol (EE2) and diethyl phthalate (DEP) exposure on microRNAs expression and their target genes in differentiated SH-SY5Y cells by Agnese Graziosi, Camilla Corrieri, Giulia Sita, Luca Ghelli, Sabrina Angelini, Roberta d’Emmanuele di Villa Bianca, Emma Mitidieri, Raffaella Sorrentino, Patrizia Hrelia, Fabiana Morroni

“…Abstract Environmental endocrine disruptor chemicals (EDCs) have raised significant concerns due to their potential adverse effects on human health, particularly on the central nervous system (CNS). …”
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Aged polylactic acid microplastics with ultraviolet irradiation stunted pakchoi (Brassica chinensis L.) germination and growth with cadmium in hydroponics by Lei Sun, Ya Liu, Yakun Feng, Zequn Fan, Lei Jiang, Can Lu, Cuiling Jiang

“…The results unraveled here emphasized that UPLA MPs, especially aged BMPs, could trigger adverse effects on agro-systems with heavy metals. Therefore, the results of this study can provide a new perspective and reference for the ecological risk evaluation of Cd and BMPs pollution in agricultural soils.…”
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A Novel Bacteriophage with the Potential to Inhibit <i>Fusobacterium nucleatum</i>-Induced Proliferation of Colorectal Cancer Cells by Ho Yin Pekkle Lam, Meng-Jiun Lai, Pin-Chun Wang, Wen-Jui Wu, Li-Kuang Chen, Hsiang-Wei Fan, Chun-Chieh Tseng, Shih-Yi Peng, Kai-Chih Chang

“…Although antibiotics are helpful in eliminating bacteria, the major problem remains the rise of potential antibiotic-resistant strains and antibiotic-associated adverse effects. Currently, bacteriophage therapy has gained interest because of its high selectivity to bacterial hosts and may become a realistic approach in treating bacteria-associated cancers. …”
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Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II by Cagri Sakalar, Suparna Mazumder, Justin M. Johnson, Cengiz Z. Altuntas, Ritika Jaini, Robert Aguilar, Sathyamangla V. Naga Prasad, Denise C. Connolly, Vincent K. Tuohy

“…We found that AMHR2-CD immunization of C57BL/6 females induced a prominent antigen-specific proinflammatory CD4+ T cell response that resulted in a mild transient autoimmune oophoritis that resolved rapidly with no detectable lingering adverse effects on ovarian function. AMHR2-CD vaccination significantly inhibited ID8 tumor growth when administered either prophylactically or therapeutically, and protection against EOC growth was passively transferred into naive recipients with AMHR2-CD-primed CD4+ T cells but not with primed B cells. …”
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Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…However, compared with that for other target organs, research on the adverse effects of NPs on the heart is limited. We aimed to investigate the toxic effects of polystyrene NPs on the heart and the associated mechanisms. …”
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Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward? by Atul P. Kulkarni, Vasant C. Nagvekar, Balaji Veeraraghavan, Anup R. Warrier, Deepak TS, Jaishid Ahdal, Rishi Jain

“…Another challenge is the spectrum of adverse effects related to the safety and tolerability profile of the currently available drugs used against GPIs which further makes the management and treatment of these multidrug resistant organisms a complex task. …”
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The impact of energy drinks on health of children and young adults - review of latest research by Klaudia Kożuchowska, Dawid Pilarz, Marcelina Szewczyk, Maria Morawska, Aleksandra Tomczyk, Julia Ufnal, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Klaudia Drewko, Kinga Jarosz

“…Conclusions  This review provides further evidence that consumption of energy drinks by children and adolescents is associated with many adverse effects for physical and mental health. Mainly predisposed systems are cardiovascular and nervous. …”
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Informal caregiving and mental health: results from the Belgian health interview survey 2013 and 2018 by Filip Van Droogenbroeck, Bram Spruyt, Pierre Gérain, Laura Van den Borre, Pierre Smith, Robby De Pauw, Sarah Dury

“…Interventions aimed at reducing the adverse effects of caregiving might need to be universally applicable to all caregivers, focusing on reducing the intrinsic burdens of caregiving tasks rather than targeting demographic subgroups.…”
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Electrocoagulation of wastewater from commercial mixing stations with dual aluminum electrode by NI Kuan, SHAN Xiaoli, QI Dong, LI Qiang, ZHANG Wenjun

“…Compared with traditional chemical flocculation, electrocoagulation could avoid secondary pollution of circulating water during the treatment process, and would not have adverse effects on the process performance of concrete, providing a new method for the scientific and efficient purification and reuse of wastewater from commercial mixing stations.…”
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Influence of Urena lobata Fibre Treatment on Mechanical Performance Development in Hybrid Urena lobata: Fibre/Gypsum Plaster Composites by Jerum Biepinwoh Kengoh, Ekane Peter Etape, Beckley Victorine Namondo, Josepha Foba-Tendo, Yakum Renata Nafu, Betene Ebanda Fabien

“…The test results showed an increment in compressive strength and reduction in autogenous shrinkage for the hybrid UL fibre/gypsum cement composites, while lower percentage additions (less than 2.5%) of untreated fibre appeared to have adverse effects on specimens. It was observed that properly dispersed (blended) treated UL fibres filled the fine pores in the cement matrix by providing an additional nucleation site that resulted in a denser microstructure, which in turn enhanced the strengths and limited the autogenous shrinkage.…”
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Interactive effects of temperature, cadmium, and hypoxia on rainbow trout (Oncorhynchus mykiss) liver mitochondrial bioenergetics by John O. Onukwufor, Collins Kamunde

“…Fish in their natural environments possess elaborate mechanisms that regulate physiological function to mitigate the adverse effects of multiple environmental stressors such as temperature, metals, and hypoxia. …”
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Assessing the influence of matcha green tea extract on NF-κB/MAPK signaling pathway activation in rats: A study on irradiation-induced acute hepatic inflammatory response by Noha Sayed Hamed, Eithar K. El Adham, Amal I. Hassan

“…Background: Numerous forms of cancer are frequently treated with radiation therapy, which provides substantial benefits in tumor control. However, adverse effects, particularly the development of severe hepatitis, may render radiation therapy ineffective. …”
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7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan by Sung-Shuo Kao, Wen-Chi Chen, Ping-I Hsu, Kwok-Hung Lai, Hsien-Chung Yu, Hui-Hwa Cheng, Nan-Jing Peng, Chiun-Ku Lin, Hoi-Hung Chan, Wei-Lun Tsai, Huay-Min Wang, Tzung-Jiun Tsai, Kung-Hung Lin, Feng-Woei Tsay

“…Patients were asked to return at the second week to assess drug compliance and adverse effects. Repeated endoscopy or urea breath test was performed at 8 weeks after the end of eradication therapy. …”
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Impact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model by Rita Araújo, Ricardo N. M. J. Páscoa, Raquel Bernardino, Pedro S. Gomes

“…Diabetes mellitus is a widespread metabolic disorder linked to numerous systemic complications, including adverse effects on skeletal health, such as increased bone fragility and fracture risk. …”
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Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella by Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min

“…Abstract Synergistic combinations of immunotherapeutic agents can improve the performance of anti-cancer therapies but may lead to immune-mediated adverse effects. These side-effects can be overcome by using a tumor-specific delivery system. …”
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Rituximab Monotherapy versus Rituximab and Bortezomib Combination Therapy for Treatment of Non-paraneoplastic Autoimmune Retinopathy by Arash Maleki, Amanda Colombo, Sydney Look-Why, BA; Peter Y Chang, Stephen D Anesi, Stephen D Anesi

“…The average improvement in b-wave amplitude (50.7% ± 29.4% [range, 25–90%]) was higher than the average improvement in a-wave amplitude (35.7% ± 9.74 [range, 25–63%]). No severe adverse effects were reported. Conclusion: Rituximab and bortezomib combination therapy may not be more effective than rituximab monotherapy in npAIR patients for most of the visual function parameters; however, this combination therapy may be more effective in improving scotopic combined rod and cone a- and b-wave amplitudes. …”
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The Role of Glucocorticoid Receptors in Dexamethasone-Induced Apoptosis of Neuroprogenitor Cells in the Hippocampus of Rat Pups by Chun-I Sze, Yung-Chieh Lin, Yuh-Jyh Lin, Ting-Hui Hsieh, Yu Min Kuo, Chyi-Her Lin

“…However, Dex treatment results in adverse effects on the brain. Since the hippocampus contains a high density of glucocorticoid receptors (GCRs), we hypothesized that Dex affects neurogenesis in the hippocampus through inflammatory mediators. …”
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Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina) by Gregory Scott, Meghan M. Louis, Julie A. Balko, Claire M. Bublitz, Brigid V. Troan, Ronald E. Baynes, Dustin Smith, Larry J. Minter

“…The mean peak plasma concentration was 6.31 µg/ml, area under the curve was 29.37 μg-h/mL, and elimination half-life was 2.79 h. No adverse effects were noted in any animals. A subset of 12 animals were euthanized at serial timepoints and necropsied. …”
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