Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre by Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves

“…Treatment was discontinued in three patients due to adverse effects. There were no treatment-related deaths reported. …”
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Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression. by Selma Hurem, Leonardo Martín Martín, Dag Anders Brede, Eystein Skjerve, Rasoul Nourizadeh-Lillabadi, Ole Christian Lind, Terje Christensen, Vidar Berg, Hans-Christian Teien, Brit Salbu, Deborah Helen Oughton, Peter Aleström, Jan Ludvig Lyche

“…The lowest dose rate corresponded to recommended benchmarks at which adverse effects are not expected to occur in aquatic ecosystems (2-10 mGy/day). …”
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Mirvetuximab Soravtansine in solid tumors: A systematic review and meta-analysis. by Shamsnur Rehim, Shuang Yuan, Hongjing Wang

“…The secondary endpoints were the Objective response rate (ORR) and adverse effects (AEs). A random-effects model was applied.…”
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Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind... by Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

“…The participants were evaluated for morphine consumption within 24 hours and postoperative pain using a verbal numerical rating scale (VNRS) at a postanesthetic care unit, at 6-, 12-, and 24-hour postoperative periods. Adverse effects were recorded. Results. Morphine consumption within 24 hours and adverse effects were not significantly different between both groups. …”
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Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnancy: A Subgroup Analysis of a Multicenter Real-World Study Involving 1191 Pregnant Women by Prakash Trivedi, S. Chitra, Suma Natarajan, Vandana Amin, Shilpi Sud, Priti Vyas, Meenakshi Singla, Ajinkya Rodge, Onkar C. Swami

“…In pregnant women with mild IDA (n = 26), Hb increased significantly by 1.99 g/dL (P<0.001). Adverse effects were reported in 8.6% of pregnant women. …”
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Observation on the Efficacy of Ginkgo Ketone Ester Drop Pill in Improving Hypertension Combined with Carotid Atherosclerotic Plaque by Jie Zhang, Yingli Ma

“…The treatment of hypertension combined with carotid atherosclerotic plaque with Ginkgo ketone ester drop pill helps to improve the blood pressure, blood lipid, and vascular endothelial function of patients and helps to inhibit the inflammation level and atherosclerotic plaque of patients, with significant efficacy and no significant adverse effects in patients, which is worthy of clinical promotion.…”
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Phage therapy in the management of respiratory and pulmonary infections: a systematic review by Patience Sarkodie-Addo, Abdul-Halim Osman, Bill Clinton Aglomasa, Eric S. Donkor

“…Regarding the safety of PT, 77.78% ( N  = 14/18) of the studies did not record any adverse effects after PT was administered, whilst 16.66% ( n  = 3/18) of the studies reported adverse effects. …”
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Phytochemical and toxicological evaluation of aqueous leaf extract of Premna integrifolia L. in male balb/c mice by Suman, Pratibha Gaurav, Rajesh Saini, Kavindra Nath Tiwari, Gautam Geeta Jiwatram

“…., followed by a fourteen-day observation period to monitor any signs of toxicity or adverse effects. In the oral subacute toxicity study, mice received daily oral gavage of the ALEPI at doses of 400, 800, and 1000 mg/kg b.wt. for twenty-eight days. …”
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Insights on the Dynamics and Toxicity of Nanoparticles in Environmental Matrices by T. Devasena, B. Iffath, R. Renjith Kumar, Natarajan Muninathan, Kuppusamy Baskaran, T. Srinivasan, Shani T. John

“…The effects of toxicity on vertebrates, invertebrates, and plants and the source of exposure, environmental and biological dynamics, and the adverse effects of some nanoparticles are discussed.…”
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A Case of Lenvatinib-Induced Focal Segmental Glomerulosclerosis (FSGS) in Metastatic Medullary Thyroid Cancer by Kathryn Fleming, James McGuinness, David Kipgen, Hilary Glen, Pavlina Spiliopoulou

“…Lenvatinib was a novel experimental agent at the time the treatment took place; however, its recent licensing for the treatment of thyroid malignancies in the UK makes reporting of these adverse effects all the more important now.…”
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A rare case of pneumomediastinum, pneumoretroperitoneum and subcutaneous emphysema due to crystal methamphetamine abuse by Abdulmajeed K. Abdulmajeed, Mansour O. Almehrzi, Saba A. Al-Bazzaz, Farah A. Khalid, Sherif A. Fathi, Ashraf F. Hefny

“…Background: Crystal methamphetamine abuse is a growing concern due to its significant adverse effects on various organ systems. Case description: This report presents a rare case of pneumomediastinum, pneumoretroperitoneum and subcutaneous emphysema resulting from crystal methamphetamine abuse. …”
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Chômage et usages de substances psychoactives by Virginie Althaus, Sébastien Ladreyt, Yannick Le Hénaff, Joëlle Mezza, Dominique Lhuilier

“…The “anaesthetic” effect or function of psychoactive substances is prevalent in the discourse of the participants and helps them to resist the adverse effects of unemployment.…”
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Indoor dynamic environment lo calization algorithm based on transfer learning by Can LIU, Junna SHANG, Ruijiang LI, Keqiang YUE

“…The accuracy of the traditional indoor fingerprint lo calization system is limited bymany factors,such as the density of the reference location node in the fingerprint database and the characteristics of the indoor environment.When the indoor environment changes dynami cally,the RSS fluctuates,and usually does notmeet the assumption of the same distribution.Therefore,it was difficult to obtain high-precision requirements for conventional fingerprint positioningmethod.Aiming at the problem that the traditional algorithm couldn’t locate accurately,an algorithm based on the indoor fingerprint database was designed and implemented.The algorithm adopted the idea ofmigration learning to embed different data sets into the latent feature space,and the adverse effects of environmental changes on the system weremitigated.The simulation results show that the average positioning error of this algorithm is 1.23m.…”
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Update on the Use of Inhaled Nitric Oxide by Robert M Kacmarek

“…This has resulted in the development of makeshift delivery systems, many of which may have the potential for adverse effects.…”
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The Implications of Mental Health and Trauma in Interstitial Cystitis by Tyler R. Bendrick, Graison L. Sitenga, Cameron Booth, Matthew P. Sacco, Christine Erie, Danyon J. Anderson, Alan D. Kaye, Ivan Urits

“…It was also established that for individuals with early traumatic experiences, the more likely the development of IC later in life, and with more severe symptoms and adverse effects on quality of life. We describe three distinct hypotheses for the possible physiologic mechanism for development of IC with relation to mental health and trauma, although definitive evidence in this area is still lacking, which poses interesting avenues for further research. …”
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La France et la mise en œuvre du protocole de Nagoya by Thomas Burelli

“…Finally, we will see that the bill proposes an original and with potentially adverse effects interpretation of the sared jurisdictions between some French territories abroad and the French state.…”
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EPİSTEMİYÂTRİ KAPISINI AÇARKEN by Ahmet İnam

“…"How can I steer my knowledge in order to avoid its supposedly unconscious adverse effects upon my life?" "What kinds of disorders might appear if I am not epistemiyatrically aware of my life with my knowledge?" …”
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Real-World Long-Term Experience on Endoxifen in Bipolar Disorder with Psychotic Symptoms by Vikas Thanvi

“…Treatment with endoxifen 8 mg once a day showed improvement in manic symptoms with a YMRS score of 4 and a reduction in the use of psychostimulants as well as other antipsychotic concomitant medications. No adverse effects were noted up to 8-month follow-up. Long-term treatment with endoxifen is safe and effective in severe BPAD.…”
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Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries by Tiziano A. Schweizer, Julia S. Würmli, Julia Prinz, Maximilian Wölfle, Roger Marti, Hendrik Koliwer-Brandl, Ashley M. Rooney, Vanni Benvenga, Adrian Egli, Laurence Imhof, Philipp P. Bosshard, Yvonne Achermann

“…On day 4, three (30%) participants per group showed positive cultures post antisepsis. Adverse effects were reported in six (60%) and zero (0%) participants for 5-ALA- and MAL-PDT-DL, respectively. …”
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Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

“…Secondly, the MP-LNP formulation effectively attenuates inflammation and reduces the adverse effects associated with high-dose MP treatment in the acute phase of SCI. …”
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