Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic... by Anna Lethicia L. Oliveira, Gisele G. L. Santos, Renan F. Espirito-Santo, Gessica Sabrina A. Silva, Afrânio F. Evangelista, Daniela N. Silva, Milena B. P. Soares, Cristiane Flora Villarreal

“…Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum-derivative chemotherapeutic agent. …”
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Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis by Lin W, Wang Q, Liu J, Tan Q

“…About 50% of participants showed fear of adverse effect of oral corticosteroids. About 89.6% of participants who received corticosteroid treatment showed their well to adhere to the doctor’s advice. …”
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The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) by V. T. Ivashkin, O. P. Alekseyeva, A. Yu. Baranovsky, Ye. K. Baranskaya, Ye. V. Beloborodova, T. A. Kolesov, N. V. Korochanskaya, K. . Lang, T. L. Lapina, I. V. Mayev, M. V. Mokshina, D. L. Nepomnyashchy, Ye. V. Onuchina, R. G. Sayfutdinov, T. H. Sviridova, V. I. Simanenkov, A. V. Tkachev, A. S. Trukhmanov, L. P. Faizova, I. B. Khlynov, O. B. Khlynova, A. A. Sheptulin

“…According to available data certain strains of probiotics are effective in decreasing of gastrointestinal adverse effects rates, associated with eradication therapy while the other can potentiate the efficacy of H. pylori eradication itself. …”
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Case report: Chest radiotherapy-induced vertebral fractures in lung cancer patients: a case series and literature review by Oscar Arrieta, Francisco Lozano-Ruiz, Alberto Guijosa, Pamela Soberanis-Pina, Monika Blake-Cerda, Ana Pamela Gómez-García, Federico Maldonado-Magos, Emilio Conde-Flores, Andrés F. Cardona, Sandra Ileana Pérez Álvarez, Luis Antonio Cabrera-Miranda

“…As survival rates in LC patients improve, the relevance of this adverse effect increases, underscoring the need for implementing bone protective strategies to further enhance patient outcomes and quality of life.…”
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Dose-dependent incidence of agranulocytosis in patients treated with methimazole and propylthiouracil by Jaeduk Yoshimura Noh, Kosuke Inoue, Nami Suzuki, Ai Yoshihara, Miho Fukushita, Masako Matsumoto, Hideyuki Imai, Shigenori Hiruma, Masahiro Ichikawa, Masakazu Koshibu, Akiko Sankoda, Rei Hirose, Natsuko Watanabe, Kiminori Sugino, Koichi Ito

“…Agranulocytosis is a serious adverse effect of methimazole (MMI) and propylthiouracil (PTU), and although there have been reports suggesting a dose-dependent incidence in relation to both drugs, the evidence has not been conclusive. …”
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Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients by Mélanie Saint-Jean, Anne-Chantal Knol, Christelle Volteau, Gaëlle Quéreux, Lucie Peuvrel, Anabelle Brocard, Marie-Christine Pandolfino, Soraya Saiagh, Jean-Michel Nguyen, Christophe Bedane, Nicole Basset-Seguin, Amir Khammari, Brigitte Dréno

“…Regarding safety, no serious adverse effect was reported. Therapeutic responses included a complete remission, a partial remission, 2 stabilizations, and 6 progressions. …”
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Fournier Gangrene Associated with Sodium-Glucose Cotransporter-2 Inhibitors: A Pharmacovigilance Study with Data from the U.S. FDA Adverse Event Reporting System by Yang Hu, Ziyu Bai, Yan Tang, Rongji Liu, Bin Zhao, Jian Gong, Dan Mei

“…Food and Drug Administration (FDA) released a safety warning of Fournier gangrene (FG), a rare but serious adverse effect of sodium-glucose cotransporter-2 (SGLT2) inhibitors in August 2018. …”
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Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial by Jiahui Zhang, Chang Liu, Guodong Ruan, Haiyan Zhang, Beiping Zhang, Xuejun Hu, Cailing Zhong

“…No auricular acupressure-related adverse effect was observed. Conclusions: Auricular acupressure can significantly decrease the incidence of ADRs to colonoscopic bowel preparation in patients and alleviate the severity of nausea and bloating symptoms, which is a safe, simple, and effective method. …”
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EFFECTS OF SMOKING ON CIRCADIAN ARTERIAL BLOOD PRESSURE PROFILE IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME AND CHRONIC KIDNEY DISEASE by Oksana Yadzhyn, Tetiana Solomenchuk

“…In the same Group, more distinct signs of kidney injury were found, namely, lower GFR values and higher ACR values, which indicates the probable adverse effect of smoking on ABP regulation and renal microvasculature.…”
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Remote Monitoring of Chemotherapy-Induced Peripheral Neuropathy by the NeuroDetect iOS App: Observational Cohort Study of Patients With Cancer by Ciao-Sin Chen, Michael P Dorsch, Sarah Alsomairy, Jennifer J Griggs, Reshma Jagsi, Michael Sabel, Amro Stino, Brian Callaghan, Daniel L Hertz

“… BackgroundChemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating adverse effect of neurotoxic chemotherapy characterized by symptoms such as numbness, tingling, and weakness. …”
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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“… Introduction Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and clinically relevant adverse effect of chemotherapy, negatively impacting patient quality of life. …”
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Effects of Dexmedetomidine as an Adjuvant in Preoperative Ultrasound-Guided Internal Branch of Superior Laryngeal Nerve Block on Postoperative Sore Throat and Hemodynamics in Patie... by Chen Z, Zhang L, Lu G, Zhang Y, Zhao D, Zhao S, Zhang H, Jin Y, Zhao X, Jin Y

“…Zheping Chen,1– 3,* Le Zhang,2,3,* Guodong Lu,2,3 Yizheng Zhang,2,3 Dexu Zhao,2,3 Shanshan Zhao,2,3 He Zhang,2,3 Yuelong Jin,4 Xin Zhao,2,3 Yanwu Jin2,3 1Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, People’s Republic of China; 2Department of Anesthesiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, People’s Republic of China; 3The second Clinical College of Shandong University, Jinan, 250033, People’s Republic of China; 4Department of Epidemiology and Health Statistics, School of Public Health, Wannan Medical College, Wuhu, 241001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Zhao; Yanwu Jin, Department of Anesthesiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, 247 Bei Yuan Street, Jinan, 250033, People’s Republic of China, Email lujnzx@sohu.com; jinyanwu_aa@163.comBackground: Postoperative sore throat (POST) is a significant adverse effect after endotracheal intubation, especially with double-lumen endotracheal tubes (DLTs). …”
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Dietary supplementation of mulberry leaf oligosaccharides improves the growth, glucose and lipid metabolism, immunity, and virus resistance in largemouth bass (Micropterus salmoide... by Donglai Zhou, Donglai Zhou, Wenhao Zhong, Wenhao Zhong, Bing Fu, Erna Li, Erna Li, Le Hao, Qingrong Li, Qiong Yang, Yuxiao Zou, Zhenxing Liu, Fubao Wang, Sentai Liao, Dongxu Xing

“…The results showed that MLO supplementation had no adverse effect on the weight gain rate, specific growth rate, feed intake, and condition factor (P > 0.05), but significantly decreased the feed conversion rate and viscerosomatic index (P< 0.05). …”
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Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women by Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova

“…Sex hormone preparations are widely used in obstetrics for the treatment of infertility and miscarriage. Possible adverse effect of sex hormone preparations during pregnancy is their potential adverse impact on the hepatobiliary system. …”
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The Effect of Feeding Different Levels of Mineral Biochar on Performance, Blood Parameters, Production and Milk Composition of Holstein Dairy Cows by Ali Khatibi Bardsiri, Reza Valizadeh, Seyed Hadi Ebrahimi, Pirouz Shakeri, Abbas Ali Naserian

“…On the last day of the experiment, two blood samples 1) containing anticoagulant and 2) without anticoagulant were drawn from the tail vein of the cows to analyze biochemical parameters and count blood cells.Results and Discussion: Adding 0.5% and 1% mineral biochar to the diet had no significant effect on dry matter consumption, body weight change and metabolic weight change, which showed that biochar did not have an adverse effect on the palatability of the diet. The effect of experimental diets on the biochemical parameters of the blood of cows showed that there is no significant difference between the treatments. …”
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The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experien... by L. Lily Rosenthal, L. Lily Rosenthal, L. Lily Rosenthal, Carola Grinninger, Sarah Marie Ulrich, Robert Dalla Pozza, Nikolaus A. Haas, Paolo Brenner, Michael Schmoeckel, Sebastian Michel, Sebastian Michel, Sebastian Michel, Christian Hagl, Christian Hagl, Jürgen Hörer, Jürgen Hörer, Jürgen Hörer

“…Odds ratio [OR] is as follows: 1.992, 95% confidence interval [CI]: 0.983–1.007, p = 0.266, aortic clamp time per minutes: OR: 1.008, 95% CI: (0.997–1.019), p = 0.164, HLM time per minutes: OR: 0.996, 95% CI: (0.991–1.001), p = 0.146, Operation time per minutes: OR: 1.000, 95% CI: (0.995–1.004), p = 0.861.ConclusionThe provision of pre-HTx VAD support does not have an adverse effect on the short- and long-term survival of pediatric patients undergoing HTx. …”
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CHARACTERISTICS OF CIRCADIAN BLOOD PRESSURE PROFILE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND THEIR ASSOCIATION WITH THYROID FUNCTION by Nataliia Kuz, Tetiana Solomenchuk

“…The findings may signal an additional adverse effect of thyroid dysfunction on arterial tone and, accordingly, BP regulation, which brings about a high risk of complications of ACS.…”
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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

“…However, the precise mechanism underpinning this adverse effect remains incompletely elucidated. Given the significance of BBR and its analogs in anti‐gout/hyperuricemia drug discovery, elucidating the mechanism by which BBR exacerbates obesity‐specific DILI warrants further investigation. …”
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Farmers’ climate change perception, impacts and adaptation strategies in response to drought in the Northwest area of Bangladesh by J.M. Adeeb Salman Chowdhury, Md. Abdul Khalek, Md. Kamruzzaman

“…Water shortage is becoming a serious issue in an area that is prone to drought because limited rainfall and excessive extraction of groundwater for irrigation can have an adverse effect on the environment and climate change.The role of adaptation in responding to drought in our country is not well-organized but it is a vital issue for agriculture and economic growth. …”
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Long-term exposure to fine particulate matter components with obesity in children and adolescents in China: The age-sex disparities and key effect modifiers by Jinling Wang, Xinyi Li, Guannan Bai, Rachel Huxley, Kejia Hu, Jinna Yuan, Xuelian Zhou, Xiaochi Zhang, Ke Huang, Guanping Dong, Wei Wu, Bingyan Cao, Rongxiu Zheng, Chunlin Wang, Haiyan Wei, Yan Liang, Hui Yao, Feihong Luo, Pin Li, Zhe Su, Ruimin Chen, Shaoke Chen, Jingsi Luo, Hongwei Du, Mireguli. Maimaiti, Jianwei Zhang, Yu Yang, Min Zhu, Qi Zhao, Junfen Fu

“…Females, children with obese parents, and those with lower levels of physical activity were more vulnerable than others. Other adverse effect modifiers for certain children included family with one child, low family income, and less sleep duration. …”
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