Tumor Budding, uPA, and PAI-1 in Colorectal Cancer: Update of a Prospective Study by Bruno Märkl, Jochen Hardt, Simon Franz, Tina Schaller, Gerhard Schenkirsch, Bernadette Kriening, Reinhard Hoffmann, Stefan Rüth

“…Conclusions. A synergistic adverse effect of PAI-1 and tumor budding in uni- and multivariable analyses was found. …”
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Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial by Danyun Fu, Dingding Wang, Wenxian Li, Yuan Han, Jie Jia

“…Propofol-induced injection pain is a common adverse effect during the induction of general anesthesia. …”
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Do Different Tooth Bleaching–Remineralizing Regimens Affect the Bleaching Effectiveness and Enamel Microhardness In Vitro? by Hamideh Sadat Mohammadipour, Parnian Shokrollahi, Sima Gholami, Hosein Bagheri, Fatemeh Namdar, Salehe Sekandari

“…The application of NaF before, during, and after the bleaching improved the microhardness of bleached enamel as the unbleached one with no adverse effect on whitening effectiveness.…”
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Comparative Study of Periodontal Health in Patients with Fixed Braces Versus Clear Aligners by Selvakumar Annamalaisamy, B.S. Malthesh, G. M. Shashikumar, Sreedhara Shantharam, P Kiran Kumar

“…Background: Orthodontic therapy is often used to cure dental malocclusions; however, since orthodontic equipment is difficult to keep clean, it might have an adverse effect on periodontal health. Clear aligners and fixed braces are two common orthodontic treatments. …”
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Response of Dry Bean to Sulfentrazone Plus Imazethapyr by Nader Soltani, Christy Shropshire, Peter H. Sikkema

“…Generally, crop injury with sulfentrazone at rates up to 140 g ai/ha alone and in combination with imazethapyr at 37.5 g ai/ha was minimal with no adverse effect on plant height, shoot dry weight, seed moisture content, and yield. …”
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Evaluating the Fatigue Resistance of the Innovative Modified-Reinforced Composite Asphalt Mixture by Gholamali Shafabakhsh, Mahdi Akbari, Hossein Bahrami

“…Thus, the introduced mixture can be a proper choice for pavements with heavy or light (with a large amount) traffic loads, which usually have a vast adverse effect on the fatigue behaviour of asphalt mixtures.…”
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Acute and Subchronic Toxicity Study of Flavonoid Rich Extract of Glycyrrhiza glabra (GutGard®) in Sprague Dawley Rats by Ranjit M. Bhide, Bharathi Bethapudi, Nehru Sai Suresh Chalichem, Muruganantham Nithyanantham, Sasi Kumar Murugan, Deepak Mundkinajeddu

“…Based on the current experimental study findings, the median lethal dose (LD50) of GutGard was found to be >5000 mg/kg b.wt and the no observed adverse effect level (NOAEL) was found to be 1000 mg/kg rat b.wt.…”
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Minimum Dietary Diversity Score and Associated Factors among Pregnant Women at Alamata General Hospital, Raya Azebo Zone, Tigray Region, Ethiopia by Kemal Jemal, Mukemil Awol

“…Low dietary diversity has a major adverse effect on mothers, fetus, and life of new born. …”
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Effect of Epoxy Resin Emulsion on the Mechanical Properties of Oil Well Cement-Based Composites by Miao He, Jianjian Song, Mingbiao Xu, Lei He, Peng Xu

“…The resin reduces the water loss of cement paste and has no adverse effect on the thickening time. The compressive strength of cement stone decreases with the increase in resin content. …”
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Survey on Tunisian Dentists’ Anti-Inflammatory Drugs’ Prescription in Dental Practice by Line Berhouma, Amira Besbes, Abdellatif Chokri, Jamil Selmi

“…Gastric problem was found to be the most mentioned adverse effect (69%). Thus, 72% of the dentists prescribed proton pump inhibitors with AI. …”
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Acute Interstitial Nephritis in a Patient with Non-Small Cell Lung Cancer under Immunotherapy with Nivolumab by Panagiotis I. Georgianos, Vasilios Vaios, Eleni Leontaridou, Georgia Karayannopoulou, Triantafyllia Koletsa, Athanasios Sioulis, Elias V. Balaskas, Pantelis E. Zebekakis

“…These agents are associated with several “immune-mediated” adverse effects, but the reported renal toxicity of ICPIs is less well defined. …”
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Influence of Channel Regulating Structures on the Transportation and Dissipation of Supersaturated Total Dissolved Gas by Yun Qing, Qian Ma, Ran Li, Xia Shen, XuJin Zhang, LinFeng Han

“…This study can provide a scientific basis for reducing the adverse effect of supersaturated TDG in fish and the construction of ecological waterway therefore.…”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…**Background:** Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can be a lifesaving treatment for hematologic malignancies, but acute graft-versus-host-disease (aGVHD) is a potentially deadly adverse effect experienced by up to half of allo-HSCT recipients. …”
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Studyng the effects of Cantharellus cibarius fungi on Opisthorchis felineus trematode and on parasite host - C57BL/6 inbred mice by M. A. Tsyganov, G. B. Vishnevetskaya, T. P. Kukina, I. V. Sorokina, M. N. Lvova, M. A. Protsenko, N. E. Kostina, D. F. Avgustinovich

“…In both cases, the state of the infected hosts, evaluated by a number of physiological and biochemical parameters (relative weight of organs, blood indices), did not deteriorate, indicating that there was no adverse effect of the C. cibarius extract. The results obtained suggest that the C. cibarius extract might have anthelmintic properties if applied as parasite larvae excyst.…”
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Neural Network-Based Parameter Estimation and Compensation Control for Time-Delay Servo System of Aeroengine by Hongyi Chen, Qiuhong Li, Zhifeng Ye, Shuwei Pang

“…These characteristic variations may have an adverse effect on the dynamic performance of the aeroengine. …”
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Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans by Ju-Sheng Zheng, Jing Yang, Tao Huang, Xiao-Jie Hu, Ming Luo, Duo Li

“…However, the results were valid only for 28 days, and that the possibility of adverse effect (liver, kidney) of chronic alcohol consumption should be considered.…”
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Effects of levothyroxine therapy on bone and mineral metabolism in hypothyroidism: a systematic review and meta-analysis by Xiaotao Li, Taotao Zhang, Hongling Zhang, Shanshan Liu, Limin Tian

“…Conclusion This systematic review and meta-analysis demonstrated that there is a slight adverse effect of LT4 replacement therapy on bone and mineral metabolism in patients with OH, while no observed effect was found in SCH patients.…”
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Determination of Adsorption of Methylene Blue Dye by Incense Stick Ash Waste and Its Toxicity on RTG-2 Cells by Virendra Kumar Yadav, Nisha Choudhary, Daoud Ali, Gokhlesh Kumar, G. Gnanamoorthy, Azhar Ulla Khan, Pankaj Kumar, S. Hari Kumar, Belachew Zegale Tizazu

“…Incense stick ash (ISA) has traces of toxic heavy metals which have an adverse effect on the environment. Every year, tonnes of ISA are disposed of in rivers and other water bodies which leads to water pollution and affects the natural water resources. …”
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Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome by Marta Vázquez, Cecilia Maldonado, Natalia Guevara, Andrea Rey, Pietro Fagiolino, Antonella Carozzi, Carlos Azambuja

“…The intensity of this adverse effect can vary from transient mild rash to Stevens–Johnson syndrome (SJS), which can be fatal mainly when LTG is coadministered with valproic acid (VPA). …”
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Myoxinol (Hydrolyzed Hibiscus esculentus Extract) in the Cure of Chronic Anal Fissure: Early Clinical and Functional Outcomes by Adolfo Renzi, Antonio Brillantino, Giandomenico Di Sarno, Francesco D’Aniello, Stefania Ziccardi, Fiorella Paladino, Francesca Iacobellis

“…At follow-up the success rate was 72.4% (21/29); median VAS score and mean anal resting pressure were significantly lower if compared with respective baseline data. The only one adverse effect of the topical application of Myoxinol 3% ointment was perianal itch, which was reported by 3,4% (1/29) of the patients available for the analysis. …”
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