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241
Sevelamer Carbonate Crystal-Induced Colitis
Published 2020-01-01“…This case vignette describes an underrecognized adverse effect of a phosphate binder, sevelamer carbonate, inducing colitis in a 47-year-old male with insulin-dependent diabetes complicated by end-stage renal disease. …”
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242
Streptomyces-derived nano-doxorubicin: Clinical status and patents granted
Published 2024-01-01“…This anthracycline antibiotic is limited by its adverse effect profile, with the main adverse effects being nausea, vomiting, alopecia, infertility, cardiotoxicity, myelosuppression and nephrotoxicity. …”
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243
Simulation and Experimental Verification of Microscopic Surface Morphology of Spiral Bevel Gears by Shot Peening
Published 2024-08-01“…However, inappropriate process parameters can cause a significant increase in gear surface roughness, which has an adverse effect on the contact performance of the tooth surface. …”
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244
Soil Creep Effect on Time-Dependent Deformation of Deep Braced Excavation
Published 2022-01-01“…This paper should be beneficial for both researchers and engineers focusing on mitigating the adverse effect of soil creep on the stability of deep braced excavations.…”
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245
Rotational Dynamics of Optically Trapped Human Spermatozoa
Published 2014-01-01“…The linear, translational motion of the sperm is converted into rotational motion on being optically trapped, without causing any adverse effect on spermatozoa. The rotational speed of sperm cells from infertile men is observed to be significantly less as compared to controls. …”
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246
Management of the Pregnant Inflammatory Bowel Disease Patient on Antitumour Necrosis Factor Therapy: State of the Art and Future Directions
Published 2014-01-01“…Although research investigating the long-term outcomes of children exposed to anti-TNF therapy in utero is limited, there is no known adverse effect on either pregnancy or newborn outcomes including infectious complications with this class of drugs. …”
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247
Methimazole-Induced Cholestatic Jaundice: A Rare Case and Literature Review
Published 2025-02-01“…Methimazole-induced cholestatic jaundice is a rare yet severe adverse effect. Patients should be aware of this complication and advised to immediately stop taking the treatment when suggestive symptoms (pruritus, jaundice, dark urine, light-colored stool) occur.…”
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248
Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model
Published 2015-01-01“…Objectives of this study were to determine the presumptive median lethal dose (LD50), the Lowest-Observed-Adverse-Effect Level (LOAEL), and histopathologic lesions caused by the naturally occurring BMAA isomer, L-BMAA, in mice. …”
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249
Web-based intervention improving quality of life among patients with type 2 diabetes in southern Karnataka, India
Published 2024-12-01“…Diabetes can impair a person’s quality of life (QoL) by having an adverse effect on their physical, psychological, social, and environmental health. …”
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250
The effect of soy isoflavones in brain development: the emerging role of multiple signaling pathways and future perspectives
Published 2024-04-01“…As a conclusion, the soy product consumption during the pre-and post-natal periods under proper range of dose showed beneficial effects in neurobehavior development, including improvement of anxiety, aggression, hyperactive behavior, and cognition, whereas their adverse effect by taking higher doses cannot be excluded. …”
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251
Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs: Focus on Topiramate, Levetiracetam, and Perampanel
Published 2018-01-01“…Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). …”
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252
Incidence and Risk Factors of Postcontrast Acute Kidney Injury in Patients with Acute Ischemic Stroke
Published 2020-01-01“…However, postcontrast acute kidney injury (PC-AKI) is a potential adverse effect of the contrast media used, which may require hemodialysis and cause a longer hospital stay. …”
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253
Safety evaluation of the food enzyme endo‐1,4‐β‐xylanase from the non‐genetically modified Trichoderma citrinoviride strain HBI‐TX01
Published 2024-12-01“…The Panel identified a no observed adverse effect level of 1101 mg TOS/kg bw, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 740. …”
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254
Safety evaluation of the food enzyme containing endo‐polygalacturonase and β‐glucosidase from the non‐genetically modified Aspergillus tubingensis strain ARO
Published 2024-12-01“…The Panel identified a no observed adverse effect level of 2217 mg TOS/kg bw per day, the highest dose tested, resulting in a margin of exposure of at least 3640. …”
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255
Cyclosporine-induced thrombotic microangiopathy in pregnant women: A case report and literature review
Published 2025-01-01“…We also reviewed previous case reports of CsA-induced TMA and summarized the possible mechanisms, characteristics, and risk factors, as well as methods to identify this rare adverse effect of CsA in pregnant women.…”
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256
Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats
Published 2019-01-01“…The “No Observed Adverse Effect Level (NOAEL)” is defined at the highest dose of 1011 CFU/kg body weight/day for lyophilized B. subtilis ZB183 Spores under the test conditions employed.…”
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257
Fetal Thymus Size in Pregnant Women with COVID-19 Infection
Published 2021-08-01“…CONCLUSION: COVID-19 seems to have no adverse effect on fetal thymus size in mild and moderate patients during the acute phase of the infection. …”
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258
Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis
Published 2014-12-01“…In addition, ethyl acetate had an adverse effect on the burst effect, while increased stirring speed had the opposite effect. …”
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259
Safety evaluation of the food enzyme fructan β‐fructosidase from the genetically modified Trichoderma reesei strain AR‐577
Published 2024-12-01“…The Panel identified a no observed adverse effect level of 1000 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, results in a margin of exposure of at least 5495. …”
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260
A Challenging Twist in Pulmonary Renal Syndrome
Published 2014-01-01“…Hydralazine-induced anti-neutrophil cytoplasmic antibody-positive renal vasculitis is a rare adverse effect and can present as a severe vasculitic syndrome with multiple organ involvement. …”
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