Evaluation of the diagnostic accuracy of two point-of-care tests for COVID-19 when used in symptomatic patients in community settings in the UK primary care COVID diagnostic accura... by Brian D Nicholson, Philip J Turner, Thomas R Fanshawe, Alice J Williams, Gayatri Amirthalingam, Sharon Tonner, Maria Zambon, Richard Body, Kerrie Davies, Rafael Perera, Simon de Lusignan, Gail N Hayward, F D Richard Hobbs, RAPTOR-C19 Study Group and the CONDOR Steering Committee

“…This study aimed to evaluate the diagnostic accuracy of two point-of-care tests (POCTs) for SARS-CoV-2 in routine community care.<h4>Methods</h4>Adults and children with symptoms consistent with suspected current COVID-19 infection were prospectively recruited from 19 UK general practices and two COVID-19 testing centres between October 2020 and October 2021. …”
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Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…Imène Gouia,1 Florence Joulain,1 Yi Zhang,2 Christopher Ll Morgan,3 Asif H Khan4 1HEVA (Health Economics and Value Assessment), Sanofi, Gentilly, France; 2Medical Affairs, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA; 3Epidemiology, Pharmatelligence Ltd, Cardiff, UK; 4Global Medical, Sanofi, Bridgewater, NJ, USACorrespondence: Imène Gouia, Sanofi, 82 Avenue Raspail, Gentilly Cedex, 94255, France, Tel +33786980603, Email Imene.Gouia@sanofi.comBackground: UK pediatric asthma prevalence is among the highest in Europe, and although the clinical and economic burden of asthma in UK adults is well described, childhood asthma data is lacking. …”
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Assessment of Risk Factors for Fractures in Patients with Type 2 Diabetes over 60 Years Old: A Cross-Sectional Study from Northeast China by Yan Guo, Yingfang Wang, Feng Chen, Jiabei Wang, Difei Wang

“…A total of 3430 elderly adults (2201 females, mean±standard deviation age 68.16±6.1 years; 1229 males, 69.16±6.7 years) were included. …”
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Les pratiques touristiques ciblées sur l’enfance : vers une nouvelle perspective ? by Fiorella Dallari, Alessia Mariotti

“…Or l‘étude de cas de destinations touristiques de premier plan consolidées dans le temps démontre le poids que représente cette classe d’âge, oubliée au profit des marchés touristiques des adultes et des seniors et privée de produits touristiques innovants. …”
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Association between life's essential 8 and Parkinson's disease: a case–control study by Jiaxin Fan, Yanfeng Wang, Xingzhi Guo, Shuai Cao, Shuqin Zhan, Rui Li

“…This study aimed to elucidate the association between LE8 metrics and PD in the US adults. Methods Data of 26,975 participants were extracted from the last 7 National Health and Nutrition Examination Survey (NHANES) cycles (2005–2018). …”
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Elevated Platelet‐to‐Lymphocyte Ratio as a Predictor of All‐Cause and Cardiovascular Mortality in Hypertensive Individuals by Rui Xu, Ling Chen, Changshun Yan, Hong Xu, Guiqiu Cao

“…Data from 15 483 hypertensive adults in the NHANES (2005–2018) were analyzed. Mortality data, including all‐cause and cardiovascular deaths, were sourced from the National Death Index (NDI) up to December 31, 2019. …”
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Assessing the financial burden of multimorbidity among patients aged 30 and above in India by Sudheer Kumar Shukla, Pratheeba John, Sakshi Khemani, Ankur Shaji Nair, Nishikant Singh, Rajeev Sadanandan

“…It was most prevalent among older adults, higher MPCE quintiles, urban patients, and those with NCDs. …”
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Metabolites induced by citrus tristeza virus and ‘Candidatus Liberibacter asiaticus’ influence the feeding behavior of Diaphorina citri: an electrical penetration graph and LC–MS/M... by Jingtian Zhang, Fengchun Xia, Yuhe Li, Yangyang Liu, Fengnian Wu, Xiaoling Deng, Meirong Xu

“…In this study, an electrical penetration graph was used to study the feeding behavior of D. citri adults on four groups of Citrus reticulata Blanco cv. …”
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Australian children’s foot, ankle and leg problems in primary care: a secondary analysis of the Bettering the Evaluation and Care of Health (BEACH) data by Hylton B Menz, Christopher Harrison, Peter A Lazzarini, Cylie M Williams, Julie Gordon

“…Unexpectedly, conditions presenting commonly in adults, but rarely in children, were also frequently recorded. …”
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Timely short-term specialised palliative home care for older people with frailty and their family: a mixed-methods pilot randomised controlled trial and process evaluation by Lieve Van den Block, Kim de Nooijer, Lara Pivodic, Peter Pype, Nele Van Den Noortgate, Rose Miranda, Kim Eecloo, Stefanie De Buyser, Aurelie Joos, Katlijn Van Mulders

“…Our secondary aim was to describe any preliminary effects of Frailty+.Design Pilot randomised controlled trial with process evaluation.Setting/Participants We aimed to recruit 50 adults (≥70 years) with Clinical Frailty Scale score 5–7, and complex care needs and their main family carer, if available, from two Belgian hospitals on discharge.Interventions Patients were randomised to the Frailty+ intervention alongside standard care or standard care alone.Outcome measures Implementation and trial feasibility were assessed through interviews, focus groups and quantitative data. …”
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Alternative approaches for monitoring and evaluation of lymphatic filariasis following mass drug treatment with ivermectin, diethylcarbamazine and albendazole in East New Britain P... by Krufinta Bun, Benedict Mode, Melinda Susapu, Joyceline Salo, Catherine Bjerum, Michael Payne, Daniel Tisch, Makoto Sekihara, Emanuele Giorgi, Gary J Weil, Peter U Fischer, Leanne Robinson, Moses Laman, Christopher L King

“…Twenty-four villages were evaluated before and after MDA in age-matched adults ( ≥  18 years). Treatment reduced CFA prevalence by 34% and Mf prevalence by 90%. …”
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Prediction of Blood Lipid Phenotypes Using Obesity-Related Genetic Polymorphisms and Lifestyle Data in Subjects with Excessive Body Weight by Omar Ramos-Lopez, Jose I. Riezu-Boj, Fermin I. Milagro, Marta Cuervo, Leticia Goni, J. A. Martinez

“…This cross-sectional study enrolled 304 unrelated overweight/obese adults of self-reported European ancestry. A total of 95 single nucleotide polymorphisms (SNPs) related to obesity and weight loss were analyzed by a targeted next-generation sequencing system. …”
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Stigmatization of people with mental illness – a matter of milieu-specific worldviews? Results from a population-based survey in Germany by Jenny Spahlholz, Eva Baumann, Sven Speerforck, Sven Speerforck, Christian Sander, Christian Sander, Matthias C. Angermeyer, Georg Schomerus, Georg Schomerus

“…We used a milieu approach to investigate how shared social, cultural and political orientations and expectations are associated with manifestations of the mental-illness related stigma.MethodsWe analyzed cross-sectional data from 3,042 adults aged ≥18 years from a national vignette-based representative survey on the stigma of mental illness in Germany from 2020. …”
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Perceived wildfire risk and past experiences with wildfire smoke influence public support for prescribed burning in the western conterminous United States by Christopher J Rogers, Celeste Beck, Rima Habre, Jo Kay Ghosh

“…Methods Data were from the May 2023 Household Emergency Preparedness Survey, an online panel survey of 1,727 adults in 12 western conterminous states, applying survey weights to reflect the underlying population demographics. …”
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Outcomes following intradetrusor onabotulinumtoxinA in a national cohort of nursing home residents by Leo D. Dreyfuss, Farnoosh Nik‐Ahd, Lufan Wang, Abigail Shatkin‐Margolis, Kenneth Covinsky, W. John Boscardin, Anne M. Suskind

“…Conclusion Among this population of NH residents, who are by definition frail and comorbid, rates of repeat onabotulinumtoxinA injections are comparable to retrospective analyses of younger adults and independent of frailty and comorbidity. …”
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Sex-specific alterations in creatine metabolism in cellular compartments of peripheral blood leukocytes in type 1 diabetes by Nina Alchujyan, Elena Aghajanova, Nina Movsesyan, Arthur Melkonyan, Artashes Guevorkian, Armen Andreasyan, Margarita Hovhannisyan

“…A total of 270 Armenian participants were enrolled in the study and were divided into two age groups: Group I - included children and preadolescents; and Group II - included adolescents and young adults. Within each group, the participants were further categorized based on sex and disease duration: Recent-onset T1D (RO-T1D), and Long-term T1D (LT-T1D). …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

“…Methods: A total of 288 P. falciparum-positive samples from children (6 months to 10 years) and adults (≥ 18 years) living in Jinja (low transmission), Kanungu (medium transmission), and Tororo (high transmission) were genotyped using seven neutral microsatellite markers. …”
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Global, regional and national sodium intakes in 1990 and 2010: a systematic analysis of 24 h urinary sodium excretion and dietary surveys worldwide by J Lennert Veerman, Sarah Lewis, John Britton, Bruce Neal, Kathryn G Andrews, Goodarz Danaei, Majid Ezzati, Yanping Li, Yu Chen, Farshad Farzadfar, Jean-Michel Gaspoz, Idris Guessous, Lital Keinan-Boker, Paul Elliott, Carukshi Arambepola, Antonia Trichopoulou, Philippos Orfanos, Martin C Gulliford, Renata Micha, Dariush Mozaffarian, Wen-Harn Pan, Shoichiro Tsugane, Habibul Ahsan, Manami Inoue, Luz Maria Sanchez-Romero, Andrew Fogarty, Christos Pitsavos, Edward Giovannucci, Stefaan De Henauw, Stephen S Lim, Cho-il Kim, Inge Huybrechts, Didier Garriguet, Simón Barquera, Katia Castetbon, Neville Calleja, Peilin Shi, Hsing-Yi Chang, Yasuhiro Matsumura, Hubert Barennes, Guansheng Ma, Shahab Khatibzadeh, Saman Fahimi, John Powles, Morteza Abdollahi, Anahita Houshiar-rad, Eda Koksal, Sahar Zaghloul, Sirje Vaask, Ana Baylin, Simon Forsyth, Rosely Sichieri, Christian Haerpfer, Ian Brown, Demosthenes B Panagiotakos, Jacqui Webster, Androniki Naska, Dorothy Gauci, Rebecca E Engell, Tim E Byers, Stephanie Smith-Warner, Ibrahim Elmadfa, Mayuree Rao, Pamela A Abbott, Enrique O Abeyá Gilardon, Suad N Al-Hooti, Wulf Becker, Peter Bjerregaard, Lesley T Bourne, Mario V Capanzana, Melanie J Cowan, Dulitha N Fernando, Regina M Fisberg, Brahmam NV Ginnela, Wilbur Hadden, Daniel J Hoffman, Nahla C Hwalla, Hajah Masni Ibrahim, Maria D Jackson, Lars Johansson, Hae-Jeung Lee, Chan Mei Fen, Gert BM Mensink, Rafael A Monge-Rojas, Balakrishna Nagalla, Marga C Ocke, Maciej Oltarzewski, Marja-Leena Ovaskainen, Gulden Ayla Pekcan, Stefka Petrova, Noppawan Piaseu, Leanne M Riley, Rusidah BT Selamat, Chansimaly Simmala, Laufey Steingrimsdottir, Gillian Swan, Lucjan Szponar, Heli Tapanainen, Robert Templeton, Anastasia Thanopoulou, Holmfridur Thorgeirsdóttir, Inga Thorsdottir, Aida Turrini, Nowak Verena, Anna Waskiewicz, Gábor Zajkás, Shadi Kalantarian, Pattra Wirojratana, Mary Anne Land, Tricia McKeever, Mohannad Abed Alfattah Al Nsour, Medical Science, Heléne Enghardt Barbieri, Aida Filipovic Hadziomeragic, Nur Indrawaty Lipoeto, Stephen T. McGarvey, Abdulrahman Obaid. Musaiger, Luz Gladys. Posada, Elz˙bieta Halina. Sygnowska

“…Objectives To estimate global, regional (21 regions) and national (187 countries) sodium intakes in adults in 1990 and 2010.Design Bayesian hierarchical modelling using all identifiable primary sources.Data sources and eligibility We searched and obtained published and unpublished data from 142 surveys of 24 h urinary sodium and 103 of dietary sodium conducted between 1980 and 2010 across 66 countries. …”
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Increasing prevalence of thyroid autoimmunity in childhood type 1 diabetes in the pre-COVID but not during the COVID era by Vivien Herczeg, Eszter Muzslay, Diána Czipó, Lili Terkovics, Johanna Takács, Réka Garai, Réka Garai, Fanni Kovács, Andrea Luczay, Anna Körner, Péter Tóth-Heyn

“…Our study aimed to analyze the prevalence of thyroid autoimmunity (TA) over a 10-year period spanning pre-pandemic and pandemic years in a population who are regularly screened for thyroid disturbances.Materials and methodsThis single-center retrospective cohort study analyzed data from 1,361 children and young adults with type 1 diabetes (T1D) treated between 2013 and 2022 in Hungary’s largest pediatric endocrinology center. …”
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The role of inflammatory system genes in individual differences in nonverbal intelligence by R. F. Enikeeva, A. V. Kazantseva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, Y. V. Kovas, E. K. Khusnutdinova

“…Within the framework of the present study, we conducted the association analysis of six SNPs in the genes that encode proteins involved in inf lammatory response regulation in the central nervous system (CRP rs3093077, IL1А rs1800587, IL1B rs16944, TNF/ LTA rs1041981, rs1800629, and P2RX7 rs2230912), with nonverbal intelligence in mentally healthy young adults aged 18– 25 years without cognitive decline with inclusion of sex, ethnicity and the presence of the “risky” APOE ε4 allele as covariates. …”
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