A Study of Molecular Mimicry and Immunological Cross-reactivity between Hepatitis B Surface Antigen and Myelin Mimics by Dimitrios-Petrou Bogdanos, Heather Smith, Yun Ma, Harold Baum, Giorgina Mieli-Vergani, Diego Vergani

“…A total of 147 samples from 58 adults were collected before HBvacc (58/58), and post-HBvacc (48/58 before the second and 41/58 before the third boost). …”
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Prognostic Modeling for Bone Sarcomas Based on a Large Prospective Cohort From a Tertiary Care Cancer Center in India by Jyoti Bajpai, Laboni Sarkar, Sushmita Rath, Akash Pawar, Arun Chandrashekharan, Goutam Panda, Dharmpal Jakar, Jaya Ghosh, Siddhartha Laskar, Bharat Rekhi, Nehal Khanna, Jifmi Jose, Mukta Ramdawar, Nilendu Purandare, Prabhat Bhargava, Nivedita Chakrabarty, Kunal Gala, Yogesh Kembhavi, Venkatesh Rangarajan, Shripad Banavali, Sudeep Gupta

“…PURPOSEOutcomes of adolescents and young adults (AYA) with bone sarcomas including osteosarcoma (OGS) and Ewing sarcoma (ES) are affected by various factors including inadvertent previous treatment and poor compliance. …”
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Computational Fluid Dynamics Analysis of Nasal Airway Changes after Treatment with C-Expander by Wang Xiao, Siling Liu, Yanqin Lu, Lei Lei, Ning Liu, Xiaoping Shen, Yuhong He, Ousheng Liu

“…The use of the C-expander is an effective treatment modality for maxillary skeletal deficiencies which can cause ailments and significantly reduce life expectancy in late adolescents and young adults. However, the morphological and dynamic effects on the nasal airway have not been reported. …”
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Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Additionally, prehypertension affects 25%–50% of adults, increasing the risk of cardiovascular complications. …”
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Association between chiropractic spinal manipulative therapy and benzodiazepine prescription in patients with radicular low back pain: a retrospective cohort study using real-world... by Jeffery A Dusek, Robert James Trager, Zachary A Cupler, Kayla J DeLano, Jaime A Perez

“…We hypothesise that utilisation of CSMT for newly diagnosed rLBP is associated with reduced odds of benzodiazepine prescription through 12 months’ follow-up.Design Retrospective cohort study.Setting National, multicentre 73-million-patient electronic health records-based network (TriNetX) in the USA, queried on 30 July 2021, yielding data from 2003 to the date of query.Participants Adults aged 18–49 with an index diagnosis of rLBP were included. …”
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Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study by Lise Colmant, Lisa Quenon, Lara Huyghe, Adrian Ivanoiu, Thomas Gérard, Renaud Lhommel, Pauline Coppens, Yasmine Salman, Vincent Malotaux, Laurence Dricot, Lukas Kunz, Nikolai Axmacher, Philippe Lefèvre, Bernard Hanseeuw

“…Results We observed that clinically normal adults with brain amyloidosis (preclinical Alzheimer’s disease) had spatial navigation deficits when relying only on self-motion cues. …”
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Effect of a Hemodialysis Session on Markers of Inflammation and Endotoxin by Shyam Dheda, David A Vesey, Carmel Hawley, David W Johnson, Magid Fahim

“…In this study, serum concentrations of endotoxin and inflammatory biomarkers, including high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), interleukin-1β (IL1β), ferritin and tumor necrosis factor (TNF), were measured in 30 adults receiving HD and 10 healthy individuals without kidney disease. …”
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Adding salt to foods and risk of incident depression and anxiety by Weiwei Wang, Xiaotian Chang, Feifei Lin, Lei Feng, Mengying Wang, Jie Huang, Tao Wu

“…Methods This study used data from 444,787 adults who had never been diagnosed with depression or anxiety at baseline from the UK Biobank, a national community-based cohort from 2006 to 2010. …”
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Impact of non-invasive oxygen reserve index versus standard SpO2 monitoring on peripheral oxygen saturation during endotracheal intubation in the intensive care unit: Protocol for... by Hugo Hille, Aurélie Le Thuaut, Pierre Asfar, Quentin Quelven, Emmanuelle Mercier, Anthony Le Meur, Jean-Pierre Quenot, Virginie Lemiale, Grégoire Muller, Martin Cour, Alexis Ferré, Asael Berge, Anaïs Curtiaud, Maxime Touron, Gaetan Plantefeve, Jean-Charles Chakarian, Jean-Damien Ricard, Gwenhael Colin, Arthur Orieux, Patrick Girardie, Mathieu Jozwiak, Manon Rouaud, Camille Juhel, Jean Reignier, Jean-Baptiste Lascarrou, CRICS-TRIGGERSEP Network

“…We designed a multicenter, two-arm, parallel-group, randomized, superiority, open trial in 950 critically ill adults requiring ETI. The intervention consists in monitoring ORI values and using an ORI target for preoxygenation of at least 0.6 for at least 1 minute. …”
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Level of physical activity of students from the police force academy in Bratislava by Gabriel Bujdos, Štefan Adamčák, Michal Marko, Anna Kozaňáková

“…By comparing our survey participants to adults from other countries we can conclude that both our male and female participants have shown higher physical activity levels.…”
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Are psychological attitudes towards vaccination an expression of personality? A cross-sectional study on COVID-19 vaccination in France by Gaëlle Lièvre, Jonathan Sicsic, Simon Galmiche, Tiffany Charmet, Arnaud Fontanet, Judith Mueller

“…Methods From February to June 2022, French adults completed self-administered questionnaires assessing COVID-19 vaccination history, the 7C antecedents, and personality traits (“ComCor” and “Cognitiv” studies). …”
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Cross-agency working when conducting a pragmatic RCT for older victims of crime: our experiences and lessons learned by Marc Serfaty, Jessica Satchell, Gloria K. Laycock, Chris R. Brewin, Marta Buszewicz, Gerard Leavey, Vari M. Drennan, Jonathan Cooke, Anthony Kessel

“…Abstract Background With the population ageing, more victims of community crime are likely to be older adults. The psychological impact of crime on older victims is significant and sustained, but only feasibility trials have been published regarding potential interventions. …”
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Profiles and predictors of access to human and veterinary healthcare in multispecies households by Jennifer W. Applebaum, Courtney Dunn, Shelby E. McDonald, Kaylinn Escobar, Erin K. King, Rosalie Corona, Megan K. Mueller

“…The third subgroup, “Good access/Medicare” (14%), primarily comprised of older adults with Medicare, reported good access to both human and veterinary care and limited financial burden, underscoring Medicare's role in stable healthcare access. …”
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Association between colorectal cancer and arthritis among Americans in 2005–2016 by Zhongbo Hou, Niping Qin, Yanlin He, Jiang Chen, Yibo Cao, Wei Xie, Tianbao Xiao

“…Methods This study utilized data from the National Health and Nutrition Examination Survey (NHANES) to investigate the relationship between arthritis and CRC among Americans. A total of 300,106 adults participated in the study, and through a questionnaire survey, they were categorized into the control group and the CRC group. …”
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Azithromycin in the Management of Upper Respiratory Tract Infections (URTIs): Indian Real-Life Experience by Dominic M, Srivastava R, Shah K, Naik SM, Rout K, Ray B, Patil D, Rana D, Swami OC

“…This study aims to evaluate the effectiveness and safety of Azithromycin in treatment of URTIs in a real-world setting.Methods: This multicenter, retrospective, observational study was conducted across 184 Ear, Nose, and Throat (ENT) clinics in India. Medical records of adults (≥ 18 years) who received Azithromycin 500 mg for 5 days to treat URTIs and provided consent were retrieved. …”
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Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review by Petra P. Larsen, MD, PhD, Virginie Dinet, PhD, Cécile Delcourt, PhD, Catherine Helmer, MD, PhD, Morgane Linard, MD, PhD

“…Clinical relevance: Age-related macular degeneration is a multifactorial disease and the leading cause of vision loss among older adults in developed countries. Clarifying whether certain infections participate in its onset or progression seems essential, given the potential implications for treatment and prevention. …”
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Clinical features of autonomic dysfunction in children with anti-N-methyl-D aspartic receptor encephalitis by Dongqing Li, Jing Sun, Guannan Li, Shuo Miao, Jian Yang, Jianzhao Zhang

“…To date, research on autonomic dysfunction in encephalitis has predominantly focused on adults, with no studies conducted on pediatric populations. …”
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Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials by Igho J Onakpoya, Elizabeth T Thomas, Joseph J Lee, Ben Goldacre, Carl J Heneghan

“…Objective To assess the benefits and harms of pregabalin in the management of neuropathic pain.Design Rapid review and meta-analysis of phase III, randomised, placebo-controlled trials.Participants Adults aged 18 years and above with neuropathic pain defined according to the International Association for the Study of Pain criteria.Interventions Pregabalin or placebo.Primary and secondary outcome measures Our primary outcomes were pain (as measured using validated scales) and adverse events. …”
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Inter-session Reliability of Magnetic Nerve Stimulation and Within-Session comparison to Electrical Nerve Stimulation in Evaluating Neuromuscular Function of Knee Extensor Muscles by Romina Ledergerber, Martin Keller

“…Methods This study compares ENS to MNS (validity) and evaluates inter-session reliability in sixteen healthy young adults (11 females, 5 males). Data on resting single twitches (RS), 3-5 superimposed twitches (ST) during maximal voluntary contractions of knee extensors, and resting doublet twitches (RD) were assessed using both MNS and ENS. …”
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Correlation between depressive symptoms and cognitive function in middle-aged and elderly population in China: an analysis of CHARLS baseline data by Yuchao SUN, Jing FENG, Zihui LEI, Ge QU, Xinyan LI, Yong GAN

“…The results of multiple linear stepwise regression showed that being female (B = – 0.31), being older (B60 – 69 years = – 0.19; B70 – 79 years = – 1.18; B80 – 89 years = – 2.12; B ≥ 90 years = – 3.66), living in central and western regions (Bcentral = – 0.36; Bwestern = – 0.57), smoking (B = – 0.15), and having depressive symptoms (Bmild to moderate = – 0.90; Bsevere = – 1.51) were risk factors for cognitive decline; further stratified analysis revealed that depressive symptoms had a significant negative impact on cognitive function in middle-aged and older adults across gender, residential area, and region of life, with higher levels of depression associated with poorer cognitive function. …”
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