Association between triglyceride-glucose index and its composite obesity indexes and cardio-renal disease: analysis of the NHANES 2013-2018 cycle by Yu Wu, Chengsen Liu, Jiandong Cao

“…BackgroundThe association between triglyceride-glucose (TYG) and its composite obesity indexes and cardio-renal disease in the American population remains insufficiently researched.MethodsThis study examined a cohort of 11,491 American adults aged 20 years and older from the 2003-2018 National Health and Nutrition Examination Survey (NHANES). …”
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Real‐World Prevalence, Treatment Patterns, and Outcomes for Patients With HER2 (ERBB2)‐Mutant Metastatic Non‐Small Cell Lung Cancer, From a US‐Based Clinico‐Genomic Database... by Sarah Waliany, Misako Nagasaka, Leah Park, Clara Lam, Zoe Jiang, Feng Lin, Joel W. Neal

“…Eligible patients were adults diagnosed with HER2‐mutant mNSCLC from January 2014 to July 2021 without co‐occuring epidermal growth factor receptor (EGFR) tumor mutations. …”
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Impact of multimorbidity and complex multimorbidity on mortality among older Australians aged 45 years and over: a large population-based record linkage study by Alamgir Kabir, An Tran, Sameera Ansari, Damian P Conway, Margo Barr

“…The relative impact of MM and CMM on mortality decreased as age increased.Conclusion MM and CMM were common in older Australian adults; and MM was a better predictor of all-cause mortality risk than CMM. …”
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Comparing physiological and psychological effects of virtual reality vs. traditional high-intensity interval training in healthy individuals: results from a preliminary pilot rando... by Jonathan Robinson, Mohammad Haziq Bin Abdul Razak

“…Objectives The study aimed to explore the feasibility, efficacy, and potential effects of VR compared to traditional HIIT in terms of physiological and psychological outcomes in physically active adults. Methods Using a parallel-design pilot randomised controlled trial, 10 participants completed the study and were randomly allocated to either the VR group (n = 5) or non-VR group (n = 5). …”
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Exploring the prevalence of gout among underrepresented low socioeconomic status type 2 diabetes populations by Jessica Smith, Abey Martin, Jane Mundadan, Michael Roberts, Youssef Roman, Arturo Bravo-Nuevo, Farzaneh Daghigh

“…Results There is an identifiable prevalence of gout among this population of low-income senior adults living with Type 2 Diabetes. Among the participants, 30.7% had serum urate levels indicative of hyperuricemia, exceeding the national average of 20.1% as reported by the National Health and Nutrition Examination Survey. …”
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Application of geographical information system and remote sensing for investigating malaria’s footprint: a case study of Iwo Metropolis, Nigeria by Joseph Olajuwon Dada, Sodiq Babatunde Rajee, Wasiu Adelani Rasak, Ayodeji Olatunbosu Ajani, Ismail Abdulraheem, Olayemi Balikis Shodeinde, Ibrahim Ademola Fetuga

“…Also, topographic maps were collected from SAS planet and Google Earth and secondary data from the State General Hospital, Iwo, where malaria data of adults above 18 years were collected which is divided into old and new cases. …”
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Risk of suicide in a sample of Egyptian high school adolescent students: a cross-sectional study by Eman S. Rabie, Marwa Soltan, Hanan Elrassas, Atteya Khairy, Moatazbellah I. Ali

“…Teenagers and younger adults commit suicide on a regular basis. In late childhood and early adulthood, it is one of the primary triggers of death. …”
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Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India by Jeffrey Pradeep Raj, Suraj Kallarakal Tomy, Amrutha Jose, Aadrika Kashyap, Joseph Varghese Kureethara, Tomy K Kallarakal

“…Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.Methods This was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. …”
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Impact of type 2 diabetes variants identified through genome-wide association studies in early-onset type 2 diabetes from South Indian population by Samuel Liju, Manickam Chidambaram, Viswanathan Mohan, Venkatesan Radha

“…Genome-wide association studies performed in European and various other populations have identified associations of numerous variants with type 2 diabetes in adults. However, the genetic component of EOT2D which is still unexplored could have similarities with late-onset type 2 diabetes. …”
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The Role of Lifestyle Factors in Controlling Blood Pressure among Hypertensive Patients in Two Health Facilities in Urban Ghana: A Cross-Sectional Study by Emefa Modey Amoah, Darlene Esinam Okai, Adom Manu, Amos Laar, Joseph Akamah, Kwasi Torpey

“…This study assessed the effect of modifiable lifestyle factors on blood pressure control among adults in urban Accra. Methods. In this cross-sectional study, 360 diagnosed hypertensive patients who were ≥18 years old, selected from two secondary-level referral hospitals in the Greater Accra Region, were interviewed. …”
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Deaths in children in England from SARS-CoV-2 infection during the first 2 years of the pandemic: a cohort study by Shamez N Ladhani, Peter Fleming, Tom Williams, Karen Luyt, Godwin Oligbu, David Odd, Sylvia Stoianova, Anna Thursby-Pelham

“…Despite social changes, and shielding of vulnerable CYP, children with life-limiting (but not necessarily life-threatening) conditions, appeared to have the highest mortality rates, similar to that seen in adults with comparable underlying conditions. The risk of death in more deprived neighbourhoods and in those from Asian and Black ethnic backgrounds was increased, and this was not explained by their other demographic characteristics.…”
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Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

“…The scale was piloted and the final version was tested in 1546 adults with multimorbidity (mean age 71 years) who took part in the 3D Study, a cluster randomised controlled trial. …”
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The Impact of Migraine on the Whole Life Course of Patients: Results from the OVERCOME (Japan) 2nd Study by Daisuke Danno, Shiho Suzuki, Tsubasa Takizawa, Ryotaro Ishii, Masayuki Hamakawa, Yoshinori Tanizawa, Satoshi Osaga, Mika Komori

“…Methods This cross-sectional, population-based, nationwide online survey was conducted in adults with or without migraine. The migraine group reported their headache features and experiences in medical management since headache onset. …”
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Cross-sectional survey of changes in knowledge, attitudes and practice of mask use in Sydney and Melbourne during the 2020 COVID-19 pandemic by Abrar Ahmad Chughtai, C Raina MacIntyre, Holly Seale, Ashley Lindsay Quigley, Mallory Trent

“…Objectives Since mask uptake and the timing of mask use has the potential to influence the control of the COVID-19 pandemic, this study aimed to assess the changes in knowledge toward mask use in Sydney and Melbourne, Australia, during the 2020 COVID-19 pandemic.Design An observational study, using a cross-sectional survey, was distributed to adults in Sydney and Melbourne, Australia, during July–August 2020 (survey 1) and September 2020 (survey 2), during the COVID-19 pandemic in Australia.Setting and participants Participants aged 18 years or older and living in either Sydney or Melbourne.Primary and secondary outcome measures Demographics, risk measures, COVID-19 severity and perception, mask attitude and uptake were determined in this study.Results A total of 700 participants completed the survey. …”
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The relationships among food neophobia, mediterranean diet adherence, and eating disorder risk among university students: a cross-sectional study by Nilufer Ozkan, Fatma Hazan Gul

“…Understanding the impact of Mediterranean diet adherence and eating disorders on dietary behaviors is crucial, particularly for young adults who are developing lifelong eating patterns. …”
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Defining remission of type 2 diabetes in research studies: A systematic scoping review. by Mireille Captieux, Regina Prigge, Sarah Wild, Bruce Guthrie

“…<h4>Methods and findings</h4>Four databases (MEDLINE, EMBASE, Cochrane Library, and CINAHL) were searched for studies published from 1 September 2009 to 18 July 2020 involving at least 100 participants with type 2 diabetes in their remission analysis, which examined an outcome of type 2 diabetes remission in adults ≥18 years and which had been published in English since 2009. …”
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Human and entomological determinants of malaria transmission in the Lihir Islands of Papua New Guinea: A cross-sectional study. by Pere Millat-Martínez, Michelle Katusele, Bernadine Kasian, Elias Omera, Esther Jamea, Lina Lorry, Aina Casellas, Dan Ouchi, Chilaka Wali, Sylvia Raulo, Arthur Elizah, Peter Kaman, Absalom Dau, Muker Sakur, Lemen Kilepak, Siub Yabu, Nelson Koata, John Kave, Michael Toa, Christopher Urakusie, Charles Kongs, Frank Kisba, Moses Laman, Oriol Mitjà, William Pomat, Quique Bassat, Stephan Karl, Bàrbara Baro

“…Children had double the infection risk compared to adults, and the use of long-lasting insecticidal-treated nets did not decrease risk of infection. …”
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Effectiveness and utilization of a cognitive screening program for primary geriatric care by David P. Salmon, Anna Malkina, Melanie L. Johnson, Christina Gigliotti, Emily A. Little, Douglas Galasko

“…Conclusion The cognitive screening program was well accepted by primary care providers as an efficient and effective way to evaluate concerns about cognitive decline in older adults.…”
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Safety and Efficacy of Hydroxypropyl Guar-Hyaluronic Acid Dual-Polymer Lubricating Eye Drops in Indian Subjects with Dry Eye: A Phase IV Study by Deborah Awisi-Gyau, Neha Kapur, Rajesh Parekh, Umesh Yeddula, Shreesha Kumar Kodavoor

“…Methods This prospective, open-label, single-arm, phase IV study was conducted in India. Inclusion criteria: Adults (18–65 years) with an average total ocular surface staining (TOSS) score ≥ 4, best-corrected visual acuity of ≥ 20/40 in each eye, tear break-up time (TBUT) ≤ 10 s, and dry eye questionnaire (DEQ-5) score ≥ 6. …”
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Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

“…This Phase 1, open-label trial randomized healthy adults to receive 62.5 mg/mL sotrovimab IM into each dorsogluteal muscle (2 × 4 mL injections), or 100 mg/mL sotrovimab IM into the dorsogluteal muscle (1 × 5 mL), the anterolateral thigh muscle (1 × 5 mL) or each deltoid muscle (2 × 2.5 mL). …”
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