Genetic interaction between oxidative stress and body mass index in a Spanish population by Francisco Lara-Hernández, Rebeca Melero, María Elena Quiroz-Rodríguez, Celeste Moya-Valera, Mariana de Jesús Gallardo-Espinoza, Luis Álvarez, Ingrid Lizeth Valarezo-Torres, Laisa Briongos-Figuero, Jessica Abadía-Otero, Francisco Javier Mena-Martin, Guillermo Saez, Josep Redon, Juan-Carlos Martín-Escudero, Ana-Bárbara García-García, Guillermo Ayala, Felipe Javier Chaves

“…Based on this premise, we studied the potential association between 723 single-nucleotide polymorphisms (SNPs) located within a set of 212 genes and both BMI and oxidative stress parameters in 1502 adults from the general Spanish population (Hortega Study). …”
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Holistic health and social care outreach for people experiencing homelessness with recent non-fatal overdose in Glasgow, Scotland: the Pharmacist and third sector Homeless charity... by Vibhu Paudyal, Nicola Greenlaw, Frances S Mair, Kate Stock, Andrew McPherson, Andrea E Williamson, Richard Lowrie, Donogh Maguire, Steven Ross, James Roy Robertson, Alison Boyle, Clare Duncan, Rebecca Blair, Cian Lombard, Fiona Hughes, Jane Moir, Ailsa Scott, Frank Reilly, Laura Sills, Jennifer Hislop, Stephen Wishart, David Brannan, Rebekah Ramage

“…Objectives To examine randomised controlled trial (RCT) progression criteria including emergency department (ED) attendance and non-fatal overdose, from a holistic, integrated health and social care outreach intervention (PHOENIx), for people experiencing homelessness with recent non-fatal street drug overdose.Design Pilot RCT. 1:1 randomisation to PHOENIx plus usual care (UC) or UC.Setting Glasgow, Scotland.Participants 128 adults experiencing homelessness with at least one non-fatal street drug overdose in the preceding 6 months.Interventions Pharmacists from the National Health Service and third sector homelessness workers offered weekly outreach. …”
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The Australian and New Zealand Fontan Registry Quality of Life Study: Protocol for a population-based assessment of quality of life among people with a Fontan circulation, their pa... by Daniel S J Costa, Kim Dalziel, Yves d’Udekem, David S Winlaw, David S Celermajer, Nadine A Kasparian, Diana Zannino, Rachel Bishop, Kate H Marshall, Susan R Woolfenden, Gary F Sholler

“…The objective of this study is to describe and develop a deeper understanding of the factors that contribute to quality of life (QOL) among children, adolescents and adults living with a Fontan circulation across Australia and New Zealand, their parents and siblings.Methods and Analysis This article presents the protocol for the Australian and New Zealand Fontan Registry (ANZFR) QOL Study, a cross-sectional, population-based study designed to examine QOL among people of all ages with a Fontan circulation, their parents and siblings. …”
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Ophthalmologists’ and patients’ perspectives on treatments for diabetic retinopathy and maculopathy in Vietnam: a descriptive qualitative study by Tunde Peto, Nathan Congdon, Lynne Lohfeld, Hoang Tran, Katie Curran, Van Thu Nguyen, Tung Thanh Hoang, Hue Thi Nguyen, Quan Nhu Nguyen, Catherine Dardis, Hoang Huy Tran, Anh Tuan Vu, Mai Quoc Tung

“…Introduction Globally, diabetic retinopathy (DR) is the leading cause of blindness in working-aged adults. Early detection and treatment of DR is essential for preventing sight loss. …”
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Adherence to First-Line Intravesical Bacillus Calmette-Guérin Therapy in the Context of Guideline Recommendations for US Patients With High-Risk Non-muscle Invasive Bladder Cancer by Franklin D. Gaylis, Bruno Emond, Ameur M. Manceur, Anabelle Tardif-Samson, Laura Morrison, Dominic Pilon, Patrick Lefebvre, Lorie A. Ellis, Hiremagalur Balaji, Andrea Ireland

“…**Objectives:** This study evaluated the adequacy of first-line intravesical BCG treatment among high-risk NMIBC patients in the United States, including the subgroup with carcinoma in situ (CIS) of the bladder. **Methods:** Adults with high-risk NMIBC treated with BCG were selected from de-identified MarketScan® Commercial, Medicare, and Medicaid Databases (1/1/2010-2/28/2021). …”
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Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study by Arsalan Tariq, Sayed Alireza Mousavi Zadeh, Muhammad Ammar, Nafisehsadat Mousavizadeh, Arash Hajary, Somayeh Mohamadi

“…These results highlight mobility, frailty and cognitive function as a predictors of comorbidities in the elderly.Conclusion Our study highlights a significant relationship between mobility, frailty and cognitive function with the comorbidity burden in older adults. Incorporating these metrics into routine care can guide targeted interventions, promoting healthier ageing and improved quality of life.…”
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Hospitalisation from seasonal influenza among persons with type 1 diabetes: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Björn Eliasson, Hanne Krage Carlsen, Lena Svensson, Magnus Gisslén, Elin Allansson Kjölhede, Oliver Martyn

“…Objectives The aim of this study was to investigate the risk of severe influenza resulting in hospitalisation among adults with type 1 diabetes (T1D).Design Nationwide cohort study using register data.Settings Data from the National Diabetes Register (NDR) linked to the Swedish Patient Register, Statistics Sweden and the Swedish Population Register.Participants Persons with T1D in the Swedish NDR n=35 596 and control persons from the Swedish Population Register matched on age, sex and county of residence, n=155 590.Primary and secondary outcomes Hospitalisation from seasonal influenza from October 2013 to December 2019. …”
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Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study by Titilola I Yakubu, Poonamdeep Jhajj, Samantha Pawer, Nicholas C West, Shazhan Amed, Tricia S Tang, Matthias Görges

“…ObjectiveThis study aimed to explore the mental health needs of adolescents with T1D, determine their preferred modalities for app-based mental health support, and identify desirable design features for peer-delivered mental health support modeled on an app designed for adults with T1D. MethodsA semistructured qualitative focus group study was conducted with adolescents with T1D and parents of adolescents with T1D. …”
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Estimating health state utilities for aromatic L-amino acid decarboxylase deficiency (AADCd) in the United States by Berrin Monteleone, Katie Forster, Gin Nie Chua, Rongrong Zhang, Andrew Lloyd, Paul Castellano, Ioannis Tomazos

“…Online composite TTO interviews were conducted 1:1 with adults from the US general public. Participants ranked health states in order of preference using a visual analog scale, then were presented with health state vignettes to elicit utilities using TTO. …”
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Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review by Mariana Herrera, Cristian Vera, Yoav Keynan, Zulma Vanessa Rueda

“…Spanish, English, and Portuguese articles comparing the concentration of IP associated with LTBI, either in plasma/serum or in vitro, in adults and nonimmunocompromised versus individuals with TB or without M. tuberculosis infection between 2006 July and 2018 July were included. …”
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Hubungan antara Pembentukan Scar Vaksin BCG dan Kejadian Infeksi Tuberkulosis by Fajriah Rosandali, Rusdi Aziz, Netti Suharti

“…</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis with the number of sufferers tend to increase every years. Adults who suffer  tuberculosis is very easy to spread it to around, especially to children. …”
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Thyroid Dysfunction in Patients with Metabolic Syndrome: A Cross-Sectional, Epidemiological, Pan-India Study by Vaishali Deshmukh, Faraz Farishta, Milind Bhole

“…In this cross-sectional study, 432 adults with an established diagnosis of MetS were enrolled across ten centers in India. …”
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A Framework for Early Detection of Acute Lymphoblastic Leukemia and Its Subtypes From Peripheral Blood Smear Images Using Deep Ensemble Learning Technique by Sajida Perveen, Abdullah Alourani, Muhammad Shahbaz, M. Usman Ashraf, Isma Hamid

“…Acute lymphoblastic leukemia (ALL), one of the prevalent types of carcinogenic disease, has been seen a deadly illness exposing numerous patients across the world to potential threats of lives. It impacts both adults and children providing a narrow range of chances of being cured if diagnosed at a later stage. …”
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Quality of life among Indonesian family caregivers caring for dependent older persons with type 2 diabetes mellitus in the community: A cross-sectional, correlational study by Rinco Siregar, Charuwan Kritpracha, Tippamas Chinnawong, Jos M. Latour

“…Background: The global prevalence of older adults with diabetes has increased, and family caregivers in Indonesia play a critical role in managing diabetes and providing personal care. …”
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Role of Dolutegravir/Lamivudine in the Management of Pregnant People Living with HIV-1: A Narrative Review by William R. Short, Parul Patel, Gustavo Verdier, Ana Puga, Vani Vannappagari, Annemiek de Ruiter, Bryn Jones

“…Pharmacokinetic data for DTG and 3TC indicate that exposures in pregnancy are within the therapeutically effective range seen in non-pregnant adults. Two studies evaluated DTG/3TC during pregnancy and both reported high virologic suppression rates [HIV-1 ribonucleic acid (RNA) < 50 copies/mL at delivery: 97% (30/31) overall], no events of vertical transmission, and no new safety signals, consistent with the use of DTG-based 3-drug regimens in pregnancy. …”
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Triatoma venosa and Panstrongylus geniculatus challenge the certification of interruption of vectorial Trypanosoma cruzi transmission by Rhodnius prolixus in eastern Colombia. by Omar Cantillo-Barraza, Lídia Gual-González, Natalia Velásquez-Ortiz, Manuel Alfonso Medina Camargo, Paola González, Lissa Cruz-Saavedra, Adriana Castillo, Sara Zuluaga, Giovanny Herrera, Hanson Cowan, Andrés Velez-Mira, Luz Helena Patiño, Juan David Ramírez, Omar Triana, Melissa S Nolan

“…Most infected humans were adults between the ages of 55 and 85 years old. No evidence of T. cruzi DNA was found using qPCR in human blood samples, but we found high parasitemia levels in the infected dogs. …”
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Investigation of the Prevalence and Diagnosis of Chronic Obstructive Pulmonary Disease in a Group of Elderly Individuals Residing in an Island Area of Ningbo by Wei Sheng, Youchang Huang, Zaichun Deng, Hongying Ma

“…This epidemiological investigation aimed at determining the current situation regarding the diagnosis and treatment of chronic obstructive pulmonary disease (COPD), especially missed diagnosis and missed treatment, in a group of individuals residing in an island area of Ningbo. Methods. Adults ≥60 years of age were selected from an island area of Ningbo. …”
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Re-imagining education in Haiti through a lens of de-coloniality by Rudolph Damas

“…Originality/value – Literacy rates in Haiti for the year 2012 were around 48% for adults and 72% for youth (UNESCO Institute for Statistics, 2012). …”
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Measurement and Analysis of Gait Pattern during Stair Walk for Improvement of Robotic Locomotion Rehabilitation System by Sang-Eun Park, Ye-Ji Ho, Min Ho Chun, Jaesoon Choi, Youngjin Moon

“…The spatial position data of joints during stair walking was obtained from six healthy adults who participated in the experiment. The measured marker data were converted into joint kinematic data by using an algorithm that included resampling and normalization. …”
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Plain Language Summary of Publication: The ProLOGUE study investigating brodalumab in people with plaque psoriasis by Shinichi Imafuku, Chika Ohata, Masaru Honma, Hidehisa Saeki, Yoko Mizutani, Takuya Miyagi, Kenta Murotani, Yasumasa Kanai

“…What happened in the study? Seventy-three adults with plaque psoriasis received brodalumab for 48 weeks. …”
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