Relationship between kidney function and healthy life expectancy: A historical cohort study by Hisayuki Ogura, Tadashi Toyama, Hikaru Samuta, Kohei Hirako, Tomoya Itatani, Shiori Nakagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Tomoyuki Takura, Takashi Wada, Yasunori Iwata

“…Methods This study of community-dwelling adults residing in Hakui City, Ishikawa Prefecture, Japan used data from the National Health Insurance database between 2012 and 2022. …”
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The association of lifestyle with cardiovascular and all-cause mortality based on machine learning: a prospective study from the NHANES by Xinghong Guo, Mingze Ma, Lipei Zhao, Jian Wu, Yan Lin, Fengyi Fei, Clifford Silver Tarimo, Saiyi Wang, Jingyi Zhang, Xinya Cheng, Beizhu Ye

“…Method A prospective cohort study was conducted using a nationally representative sample of adults aged 40 years or older, drawn from the US National Health and Nutrition Examination Survey from 2007 to 2010. …”
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Superstition in Surgery: A Population-Based Cohort Study to Assess the Association Between Surgery on Friday the 13th and Postoperative Outcomes by Sanjana Ranganathan, MBE, Carlos Riveros, MD, Michael Geng, BS, Courtney Chang, MD, Yusuke Tsugawa, MD, MPH, PhD, Bheeshma Ravi, MD, PhD, Zachary Melchiode, MD, Siqi Hu, MD, PhD, Kathleen Kobashi, MD, MBA, Brian J. Miles, MD, Zachary Klaassen, MD, MSc, Avery Nathens, MD, MPH, PhD, Natalie Coburn, MD, MPH, Allan S. Detsky, MD, PhD, CM, Angela Jerath, MD, MSc, FRCPC, FANZCA, Christopher J. D. Wallis, MD, PhD, FRCSC, Raj Satkunasivam, MD, MS

“…A retrospective, population-based cohort study of 19,747 adults undergoing 1 of 25 common surgical procedures on Friday the 13th or flanking control Fridays (Friday the 6th and Friday the 20th) between January 1, 2007, and December 31, 2019, with 1 year of follow-up. …”
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Pre-gestational diabetes in a young woman with a pathogenic INSR missense mutation, p.(Met1180Lys) by Emma L Prehn, Mairéad Crowley, David Fennell, Brendan T Kinsley, Kevin Colclough, Maria M Byrne

“…The phenotype is variable, ranging from neonatal hyperinsulinaemic hypoglycaemia to fasting or post-prandial hypoglycaemia in adults to diabetes. We report a 29-year-old woman presenting at 13 weeks gestation in her second pregnancy. …”
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Harnessing national data systems to understand circumstances surrounding veteran suicide: linking Department of Veterans Affairs and National Violent Death Reporting System Data by Claire A. Hoffmire, Alexandra L. Schneider, Laurel A. Gaeddert, Joseph Logan, Julie A. Kittel, Ryan Holliday, Lindsey L. Monteith

“…Abstract Background Veterans are at elevated risk for suicide compared to non-Veteran U.S. adults. Data sources and analyses to inform prevention efforts, especially for those who do not use Department of Veterans Affairs (VA) healthcare services, are needed. …”
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Age-stratified trends and outcomes of inpatient cholecystectomy for acute cholecystitis in the United States by Ayesha P. Ng, Joseph E. Hadaya, Sara Sakowitz, Zihan Gao, James Wu, Peyman Benharash

“…We aimed to characterize trends in utilization and outcomes of inpatient cholecystectomy across the United States stratified by age. Methods: All adults undergoing nonelective, laparoscopic cholecystectomy for acute cholecystitis in the 2012–2021 National Inpatient Sample were identified. …”
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Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democrati... by Oliver Cumming, Andrew S Azman, Espoir Bwenge Malembaka, Jackie Knee, Placide Okitayemba Welo, Aimé Cikomola, Aybüke Koyuncu, Patrick Musole Bugeme, Juan Dent, Chloe Hutchins, Hanmeng Xu, Karin Gallandat, Joseph Matundanya, Delphin Rukakiza, Merveille Nkombo, Jaime Saidi Mufitini, Baron Bashige Rumedeka, Laurent Akilimali, Elizabeth C Lee

“…Vaccine refusal was associated with a lack of confidence in the vaccine’s safety, and 29% of unvaccinated adults reported it was unlikely they would accept kOCVs if an additional mass vaccination campaign was conducted in their area. …”
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Gastrointestinal symptoms and bowel habits in 53 046 healthy Danish blood donors: a nationwide cross-sectional study by Christian Erikstrup, Ole Birger Pedersen, Henrik Hjalgrim, Erik Sørensen, Jens Frederik Dahlerup, Klaus Rostgaard, Mikkel Steen Petersen, Sisse Rye Ostrowski, Susan Mikkelsen, Khoa Manh Dinh, Thorsten Brodersen, Janna Nissen, Anne Karmisholt Grosen, Jens Kjærgaard Boldsen, Simon Mark Dahl Baunwall, Mie Topholm Bruun, Bitten Aagaard, Christina Mikkelsen, Christian Lodberg Hvas

“…The acid regurgitation and/or heartburn only phenotype associated with obesity, and the remaining symptomatic phenotypes were associated with female sex, decreasing age, and an irregular defaecation pattern, even after excluding individuals with self-reported irritable bowel syndrome, lactose intolerance, or gluten intolerance.Conclusion Most healthy adults, especially women younger than 50 years, experience gastrointestinal symptoms. …”
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Exploring avocado consumption and health: a scoping review and evidence map by Stephen A. Fleming, Tristen L. Paul, Rachel A. F. Fleming, Alison K. Ventura, Megan A. McCrory, Corrie M. Whisner, Paul A. Spagnuolo, Louise Dye, Jana Kraft, Jana Kraft, Nikki A. Ford

“…Studies were largely conducted in the United States or Latin America and generally included adults, with overweight/obesity, frequently with elevated lipid concentrations. …”
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Strategies to mitigate the impact of the COVID-19 pandemic on child and youth well-being: a scoping review protocol by Jeanna Parsons Leigh, Henry T Stelfox, Perri R Tutelman, Diane L Lorenzetti, Melanie C Anglin, Kirsten M Fiest, Stephana Julia Moss, Emily A FitzGerald, Stacie Smith, Micaela Harley, Kathryn Birnie, Sara J Mizen

“…Introduction Children and youth are often more vulnerable than adults to emotional impacts of trauma. Wide-ranging negative effects (eg, social isolation, lack of physical activity) of the COVID-19 pandemic on children and youth are well established. …”
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Brief Warm and Aldo-Keto Reductase Family <i>AspiAKR1B1</i> Contribute to Cold Adaptation of <i>Aleurocanthus spiniferus</i> by Zhi-Fei Jia, Yan-Ge Cui, Meng-Yuan Liu, Jeremiah Joe Kabissa, Yong-Yu Xu, Zhi-Wei Kang, Zhen-Zhen Chen

“…<i>Aleurocanthus spiniferus</i> not only damages plant leaves directly but also causes a sooty blotch due to the honeydew secreted by the nymphs and adults. This pest is widespread and seems to be spreading from low latitude to higher latitude areas where winters are typically colder, indicating an increase in its cold tolerance. …”
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Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation by Hermine Counil, Rummenigge Oliveira Silva, Jean‐Michel Rabanel, Charlotte Zaouter, Mohamed Haddad, Mohamed Raâfet Ben Khedher, Davide Brambilla, Tamas Fülöp, Shunmoogum A. Patten, Charles Ramassamy

“…The objective of our study was to compare the passage of pEVs from adults, cognitively healthy elderly, and AD patients through the blood‐brain barrier (BBB), to evaluate their uptake in the brain and to assess their impact on the microglia activity using in vitro and in vivo models. …”
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DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

“…This protocol describes a study to evaluate the effectiveness of a PPI deprescribing intervention in comparison to usual care in the Swiss primary care setting.Design An open-label, cluster randomised controlled trial.Setting Swiss primary care settings.Participants Included participants will be adults with inappropriate PPI treatment and will be recruited by general practitioners (GPs). …”
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Pathogenetic Treatment of Gastritis as a Basis for the Prevention of Gastric Cancer in the Countries of the Commonwealth of Independent States: Literature Review and the Resolution... by V. T. Ivashkin, I. V. Maev, J. V. Gorgun, K. S. Kaliaskarova, M. M. Karimov, A. V. Kononov, T. L. Lapina, N. A. Markaryan, M. S. Moldobaeva, S. I. Pimanov, A. A. Sheptulin

“…The proportion of infected adults in the population ranges from 60 % to over 90 %. …”
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Exploring the boundaries of anastomotic leak: experience in a high-volume center by Carolina Riscanevo Bobadilla, Gloria Flórez Dussan, Jorge Vargas, Liliana Suarez, German Jimenez, Carlos Gonzalez, Andrea Carolina Córdoba, Wilmar Martín, Diego Olivera, Raúl Guevara

“…Materials and methods A retrospective cohort study reviewed adults undergoing total gastrectomy for gastric cancer who developed esophagojejunal anastomotic leaks. …”
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Polycyclic Aromatic Hydrocarbons in Atmospheric PM2.5 during Winter Haze in Huang-gang, Central China: Characteristics, Sources and Health Risk Assessment by Mingming Shi, Tianpeng Hu, Yao Mao, Cheng Cheng, Weijie Liu, Qian Tian, Zhanle Chen, Xinli Xing, Shihua Qi

“…BaPeq concentration combined with ILCR values was used to evaluate health risk and the results showed this haze had potential health risk to both adults and children.…”
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PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle by Hiroki Iida, Minako Kawai-Takaishi, Yoshihiro Miyagawa, Yasuhiko Takegami, Akiyoshi Uezumi, Takeshi Honda, Shiro Imagama, Tohru Hosoyama

“…Since ectopic fat accumulation is frequently found in the skeletal muscles of older adults and also muscular dystrophy patients, PDZRN3 and its related pathways may represent a novel therapeutic target for these muscle pathologies.…”
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Evaluation of Inflammatory, Cardiac and Hematological Parameters in Hospitalized Children with COVID-19 by Damla Geçkalan, Rahmi Özdemir, Zülal Yılmaz, Onur Sivas, Yasin Yılmaz, Cemile Hilal Çelik

“…Objective: The relationship between clinical symptoms such as inflammatory and coagulation parameters, which are very common in adults, is still unclear in children with coronavirus disease-2019 (COVID-19). …”
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Considering Comorbidities and Individual Differences in Testing a Gaming Behavioral Activation App for Perinatal Depression and Anxiety: Open Trial Pilot Intervention Study by Gabriella E Hamlett, Chloe Schrader, Craig Ferguson, Lauren A Kobylski, Rosalind Picard, Joseph J Locascio, Richard J McNally, Lee S Cohen, Rachel Vanderkruik

“…ObjectiveWe assessed whether there were differences in symptom trajectories in pregnant participants with CAD as compared to those with depression only (ie, major depressive disorder [MDD]) during intervention with a BA mobile gaming app. MethodsPregnant adults with either CAD (n=10) or MDD (n=7) used a BA app for 10 weeks and completed biweekly symptom severity questionnaires for depression and anxiety. …”
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Breast Cancer Survivors’ Diet and Physical Activity Preferences and Barriers: How COVID-19 Changed the Intervention Landscape by Xin Chen, Chungyi Chiu, Helen Hoi Ting Cheung, Sylvia L Crowder, Xi Chen, Linda Trinh, Anna E Arthur

“…Methods: A cross-sectional survey was administered to adults diagnosed with ductal carcinoma in situ or stage I–IV breast cancer (BC) from 2019 to 2021 regarding interest, preferences, and barriers to participating in diet and exercise interventions. …”
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