Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry by Frederick L Locke, Grant Schofield, Marcelo Pasquini, Matthew J Frigault, Cameron J Turtle, Stephen Lim, Brian Hill, Samantha Jaglowski, Caron A Jacobson, Gunjan Shah, Daniel J Landsburg, Michael Heim, Stephen Ronan Foley, Ron Ram, Peter A Riedell, Leslie L Popplewell, Ranjan Tiwari, Marta Majdan, Aisha Masood

“…Background Tisagenlecleucel, a CD19 chimeric antigen receptor T-cell therapy, is approved for adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) or high-grade B-cell lymphoma (HGBCL) after ≥2 lines of therapy. …”
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Connecting the uninsured to care: Engaging new primary care patients at a new York City safety net system by Caroline Cooke, Christine Zhang, Jonathan Jiménez, Remle Newton-Dame

“…Methods: We reviewed demographics and diagnoses for 14,953 NYC Care adults who first visited primary care between November 1, 2020 and October 31, 2021, along with their total primary care visits, referrals, specialty visits, and acute visits one year following care initiation. …”
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Association Between Surgeon Sex and Days Alive at Home Following Surgery: A Population-Based Cohort Study by Kiyan Heybati, BHSc, Raj Satkunasivam, MD, MS, Khatereh Aminoltejari, MD, MSc, FRCSC, Hannah S. Thomas, MBChB, MS, Arghavan Salles, MD, PhD, Natalie Coburn, MD, MPH, Frances C. Wright, MD, Med, FRCSC, Lesley Gotlib Conn, PhD, Amy N. Luckenbaugh, MD, Sanjana Ranganathan, MD, Carlos Riveros, MD, Colin McCartney, MBChB, PhD, FRCA, FFARCSI, FRCPC, Kathleen Armstrong, MD, MSc, FRCSC, Barbara Bass, MD, Allan S. Detsky, MD, PhD, CM, Angela Jerath, MD, MSc, Christopher J. D. Wallis, MD, PhD

“…We conducted a retrospective study of adults (≥18 years of age) undergoing common surgeries between January 01, 2007 and December 31, 2019 in Ontario, Canada. …”
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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…Methods: This retrospective study compared surgical and systemic non-surgical treatments (except targeted therapy) among adults diagnosed with stage IIIA NSCLC 2017–2021. …”
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Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol by Alison B Rushton, Nicola R Heneghan, Taweewat Wiangkham, Uchukarn Boonyapo, Piyameth Dilokthornsakul, Nattawan Phungwattanakul

“…However, optimal management specifically for those who are middle-aged or older adults (≥45 years) is not available; and important considering our ageing population.Methods and analysis A systematic review with network meta-analysis (NMA) will be conducted following the Cochrane guidelines. …”
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Usefulness of Routine Terminal Ileoscopy and Biopsy during Colonoscopy in a Tropical Setting: A Retrospective Record-Based Study by Hasitha Srimal Wijewantha, Arjuna Priyadarsin de Silva, Madunil Anuk Niriella, Nethini Wijesinghe, Prabahvi Waraketiya, Ravindu Sujeewa Kumarasena, Anuradha Supun Dassanayake, Janaki de Silva Hewawisenthi, Hithanadura Janaka de Silva

“…Materials and Methods. All consenting adults undergoing colonoscopy had routine TI and biopsy. …”
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Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study by Lian-Zhen Huang, Ze-Bin Ni, Wei-Feng Huang, Li-Ping Sheng, Yan-Qing Wang, Jin-Yan Zhang

“…This study aimed to investigate the association between CVH and MASLD. Methods 5680 adults aged ≥ 20 years from the National Health and Nutrition Examination Survey 2017-March 2020 were included. …”
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High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor? by Stian Magnus Staurung Orlien, Tekabe Abdosh Ahmed, Nejib Yusuf Ismael, Nega Berhe, Trine Lauritzen, Svein Gunnar Gundersen, Asgeir Johannessen

“…The aims of the present study were (i) to assess the prevalence of autoantibodies typical for autoimmune liver diseases in a healthy population in Ethiopia and (ii) to explore the hypothesis that khat usage triggers autoimmunity. Methods. Consenting adults (≥18 years) without known autoimmune disease or manifest liver disease were included. …”
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Mobile health van as an intervention to provide clinical support and health promotion to street children and marginalised populations in the National Capital Region of Delhi: a mix... by Shanti Raman, Rajeev Seth, Yawar Qaiyum, Tanu Girotra Girotra, Id Mohammad, Indra Taneja

“…Qualitative data were provided by two recent focus group discussions carried out in the community; one with 18 mothers and another with a mixed group of 12 adults—all had used MHV clinics for children in their families. …”
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Changes in serum sodium concentration during hemodialysis is a predictor of mortality and cardio-cerebrovascular event by Qixing Liu, Ke Zheng, Haiyun Wang, Dan Song, Xuemei Li

“…However, few studies have focused on the change in SNa (ΔSNa = post-HD SNa – pre-HD SNa) during an HD session.Methods In a retrospective cohort of maintenance HD adults, all-cause mortality and cardio-cerebrovascular event (CCVE) were followed up for a medium of 82 months. …”
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Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis by Mohamed A. Shebl, Eman Toraih, Menna Shebl, Ahmed Mosaad Tolba, Parisa Ahmed, Harshdeep Singh Banga, Mohab Orz, Mahmoud Tammam, Keroles Saadalla, Mohamed Elsayed, Mennatallah Kamal, Mohamed Abdulla, Ahmed Ibrahim Eldessouky, Yousef Tarek Moustafa, Omar Ahmed Mohamed, Hani Aiash

“…Preoperative anxiety was associated with postoperative delirium in adults (OR = 1.90, 95% CI: 1.11–3.26), unlike the pediatric population. …”
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The Utah Population Database. A Model for Linking Medical and Genealogical Records for Population Health Research by Ken R. Smith, Alison Fraser, Diana Lane Reed, Jahn Barlow, Heidi A. Hanson, Jennifer West, Stacey Knight, Navina Forsythe, Geraldine P. Mineau

“…Demographers and other social scientists are increasingly using the UPDB to study issues such as trends in fertility transitions and shifts in mortality patterns for both infants and adults. A central component of the UPDB is an extensive set of Utah family histories, in which family members are linked to demographic and medical information. …”
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Surveillance of tick-borne encephalitis virus foci in Slovakia: A seroprevalence study in ruminants combined with virus detection in ticks by Martina Ličková, Bronislava Víchová, Markéta Derdáková, Monika Sláviková, Sabína Fumačová Havlíková, Dana Zubriková, Diana Selyemová, Michal Chvostáč, Lucia Blaňarová, Viktória Čabanová, Veronika Vaňová, Lucia Šulejová, Jana Kerlik, Tomáš Szemes, Katarína Šoltys, Boris Klempa

“…The estimated prevalence in adults was lower (2.15 %) than in nymphs (2.9 %). …”
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Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021 by Linmin Zhuge, Xiaowu Lin, Ziwei Fan, Mengxian Jia, Chaowei Lin, Minyu Zhu, Honglin Teng, Guoliang Chen

“…MM primarily affects older adults, with the highest incidence observed in the 70–74 age group and the highest mortality rate recorded in the same age range.ConclusionMM presents an escalating global health challenge. …”
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Real-world enrollment for a prospective clinico-genomic database using a pragmatic technology-enabled platform by Alexia Exarchos, Ariel B. Bourla, Maneet Kaur, Katja Schulze, Sophia Maund, Yi Cao, Yihua Zhao, Elizabeth H. Williams, Sarah C. Gaffey, Richard Zuniga, Shaily Lakhanpal, Vladan Antic, Michelle Doral, Johanna Sy, Neal J. Meropol, Anne C. Chiang

“…The objective was to evaluate the feasibility of a pragmatic, technology-enabled platform at community-based research sites for development of a prospective clinico-genomic database supported by centralized electronic health record (EHR)–based patient ascertainment and data processing. Methods: Adults with stage IV or recurrent metastatic non-small cell lung cancer or extensive-stage small-cell lung cancer were enrolled at 23 US sites upon initiating a standard line of therapy. …”
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Treatable traits in idiopathic pulmonary fibrosis: focus on respiratory tract infections—a systematic review and a meta-analysisResearch in context by Zsombor Matics, Anna Bardóczi, Csongor Galkó, Bence Szabó, Noémi Gede, Zsolt Molnár, Gábor Duray, Caner Turan, Péter Hegyi, Gábor Horváth, Veronika Müller

“…Only randomized controlled trials of drugs intended for IPF treatment in adults and reporting RTI incidence were included. …”
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Diagnostics and treatment of exocrine pancreatic insufficiency: clinical guidelines of the Russian gastroenterological Association by V. T. Ivashkin, I. V. Mayev, A. V. Okhlobystin, S. A. Alekseyenko, Ye. V. Beloborodova, Yu. A. Kucheryavy, T. L. Lapina, A. S. Trukhmanov, I. B. Khlynov, M. V. Chikunova, A. A. Sheptulin, O. S. Shifrin

“…The starting dose of pancreatic enzymes for adults is 25 000 units of lipase per meal, which should be subsequently increased up to achievement of complete response confirmed by both clinical and laboratory scores. …”
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Characterization of the Effects of a Six-Month Dancing as Approach for Successful Aging by Maria Grazia Vaccaro, Giulia Izzo, Alessandro Ilacqua, Silvia Migliaccio, Carlo Baldari, Laura Guidetti, Andrea Lenzi, Aldo Quattrone, Antonio Aversa, Gian Pietro Emerenziani

“…Positive effects of dance practice on several health issues have been evaluated in young adults, while the effects of regular social dance practice on physical fitness, sexual health, and cognitive functions have not been studied yet in older experienced dancers. …”
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May Measurement Month 2020: An Analysis of Blood Pressure Screening Results From China by Xin Chen, Li‐Ping Zhang, Xiao‐Long Wang, Ning‐Ru Zhang, Jing Yu, Li‐Ying Xu, Tong‐She Li, Hong Luan, Juan Zhang, Ya‐Min Hu, Dan Liu, Qi‐Dong Zheng, Yan Li, Ji‐Guang Wang

“…The study participants were adults (≥ 18 years), ideally in whom blood pressure had not been measured in the previous year. …”
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Comparing acceptance of smoking cessation and smoke-free home intervention offers and associated factors among people with low income in the USA: baseline results of a randomised c... by Matthew W Kreuter, Michelle C Kegler, Jennifer Wolff, Amy McQueen, Lauren Grimes, Enguday Teshome, Rachel Garg, Tess Thompson, Kelly Carpenter

“…Whites were less likely, and older adults and those with greater nicotine dependence were more likely, to accept the quitline offer.Conclusions Proactive approaches identified many low-income people who smoke and offering an SFH intervention retained many more of them in tobacco control efforts. …”
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