A longitudinal study to COVID-19 infection among university students: Physical fitness changes and psychological responses by Yuning Hao, Jay Lee, Water Soi Po Wong, Frankie U. Kei Wong, Walter Heung Chin Hui, Gasper Chi Hong Leong, Zhaowei Kong

“…Background: The impact of COVID-19 infection on physical and mental health of young adults remains unclear. This study aimed to investigate the changes in the physical fitness three months after recovering from acute COVID-19 infection, and examine if the infection could also influence the mental health of university students. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Background: Osteoarthritis of the knee joint (OAK) represents a leading cause of pain, functional limitation, and diminished quality of life, particularly among older adults. The association between metabolic syndrome (MetS) and OAK is of growing interest due to the potential impact of MetS components on joint health. …”
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Parents’ Experiences and Sexual Topics Discussed with Adolescents in the Accra Metropolis, Ghana: A Qualitative Study by Elizabeth AKu Baku, Isaac Agbemafle, Agnes Millicent Kotoh, Richard M. K. Adanu

“…Traditionally, discussion about sexuality is subdued in proverbs and is earmarked for adults. However, adolescents also need information about their sexuality to make informed choices regarding sexual behaviours. …”
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Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers by Aketilieke Nusufujiang, Mulalibieke Heizhati, Nanfang Li, Ling Yao, Wenbo Yang, Hui Wang, Mei Li, Lin Gan, Adalaiti Maitituersun, Miaomiao Liu, Qiaolifanayi Nuermaimaiti, Li Cai, Xiayire Aierken, Xiufang Li, Qin Luo, Jing Hong

“…Therefore, we aimed to explore whether PAC is associated with cognitive performance in this population.MethodsWe cross-sectionally enrolled adults using multistage random sampling from Emin, China in 2019. …”
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Protocol for a meta-review of interventions to prevent and manage ICU delirium by Andrew Booth, Maria Pufulete, Ben Gibbison, Burak Kundakci, Katherine Louise Jones

“…We will include all critically ill adults (aged≥18 years) and any ICU delirium prevention or management intervention (pharmacological or non-pharmacological). …”
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

“…ABSTRACT Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine capable of protecting adults from pulmonary TB. The bacterial surface is a critical interface that shapes host-pathogen interactions. …”
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Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma by Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly

“…Erdafitinib is an oral fibroblast growth factor receptor (FGFR) kinase inhibitor approved by the FDA for the treatment of adults with la/mUC harboring FGFR alterations whose disease progressed following at least 1 prior line of therapy, including a PD-1 or PD-L(1) inhibitor, based on the phase 3, randomized THOR trial (NCT03390504, Cohort 1). …”
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Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study by Songfeng Zhao, Yangbin Cao, Hongyi Liu, Aihua Liu

“…Methods and results This study included 16,190 adults with hypertension from the National Health and Nutrition Examination Survey (NHANES) 1999–2018. …”
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Correlation between salivary ANG-2 level and inflammation activity of oral lichen planus by XIANG Yuanyi, LUO Jingjing, LI Haiyang, WU Zhongting, ZHOU Hongmei

“…Methods Eighty-nine OLP patients were included, and divided into four subgroups as non-erosive asymptomatic (NEA), non-erosive symptomatic (NES), minor-erosive (MIE) and major-erosive (MAE) groups. Fifteen healthy adults were recruited as controls. Whole unstimulated saliva was collected from each participant, and the salivary ANG-2 level was measured by chemiluminescence immunoassays (CLIA) for analysis. …”
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Spicy food intake and overweight/obesity in rural Southwest China: findings from a cross-sectional study by Huali Xiong, Huali Xiong, Peng Zhao, Fengxun Ma, Dayi Tang, Daiqiang Liu

“…Subgroup analyses stratified by gender and age group, as well as sensitivity analyses, have consistently revealed a similar association between spicy food intake/the frequency of spicy food intake and overweight/obesity.ConclusionThis study could provide additional evidence for overweight and the obesity epidemic among rural adults in southwest China. Reducing spicy food intake might benefit from weight management.…”
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Evaluation of Neutralizing Capacity of Tixagevimab plus Cilgavimab (AZD7442) against Different SARS-CoV-2 Variants: A Case Report Study with Comparison to a Vaccinated Population by Constant Gillot, Jean-Louis Bayart, Vincent Maloteau, Jean-Michel Dogné, Jonathan Douxfils, Julien Favresse

“…AZD7442 (150 mg of tixagevimab plus 150 mg of cilgavimab) has been approved for the preexposure prophylaxis of COVID-19 and for the treatment of adults and adolescents with COVID-19 who do not require supplemental oxygen and who are at increased risk of severe COVID-19. …”
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Saffron therapy for the ongoing treatment of age-related macular degeneration by Peter J McCluskey, Thomas Hong, Andrew A Chang, John Grigg, Geoffrey K Broadhead, Timothy E Schlub, Eugenia Chu

“…Objective To assess the long-term efficacy and safety of oral saffron, a natural antioxidant, in treating mild/moderate age-related macular degeneration (AMD).Methods and analysis Open-label, extension trial of 93 adults (>50 years) with mild/moderate AMD and vision >20/70 Snellen equivalent in at least 1 eye. …”
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Area deprivation and premature cardiovascular mortality: a nationwide population-based study in South Korea by Hyeon Chang Kim, Hokyou Lee, Eunji Kim, Donald Lloyd-Jones, Young Gyu Ko, Byoung Gwon Kim

“…Mortality rates for CVD and its subtypes, namely ischaemic heart diseases, other heart diseases and cerebrovascular diseases, in adults under 65 years were directly standardised by sex and age, referencing the total population structure. …”
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Epidemiological analysis of reported acute glyphosate poisoning in Malaysia: identifying risk factors and high-risk groups (2006–2023) by Yin-Hui Leong, Noor Afiza Abdul Rani, Mohd Fadhli Razali, Nurul Iffah Amir Shah Ruddin, Fahim Mohamed, Nurul Izzah Ahmad

“…From 2013 to 2023, 73.7% of cases were minor, 11.5% moderate, 0.8% severe and 0.1% fatal.Conclusions In Malaysia, the reported intentional glyphosate poisoning most commonly affects young adults, resulting in generally minor to moderate symptoms. …”
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Formulation and In Vitro Evaluation of Oral Capsules from Liquid Herbal Antimalarials Marketed in Ghana by Christina Osei-Asare, Fredrick William Akuffo Owusu, Philomena Entsie, Ama Kwansima Annan, Rita Akosua Gyamaa, Edem Makafui Amenuke

“…In Sub-Saharan and tropical regions of Africa, malaria continues to claim the life of one out of every twenty children below the age of five years. In adults, mortality rates are lower, but frequent debilitating attacks reduce the quality of life for chronic sufferers. …”
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Effectiveness of dry needling combined with eccentric strength training in lateral epicondylalgia with trigger points by Sukumar Shanmugam, Lawrence Mathias, Ramprasad Muthukrishnan, Praveen Kumar Kandakurti, Satheeskumar Durairaj

“…Introduction Lateral epicondylalgia (LE) is commonly presented with myofascial trigger points (MTrPs) among adults. Dry needling (DN) is used less frequently as a first-line treatment in LE with trigger points, and the short and long-term effectiveness of DN in these populations were not studied. …”
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Adverse childhood experiences and perceived body size across the life course: a longitudinal study using data from the Canadian Longitudinal Study on Aging (CLSA) by Jean-Eric Tarride, Laura N Anderson, Lauren Griffith, Andrea Gonzalez, Vanessa De Rubeis

“…Objectives of this study were to define trajectories of body size across the life course and to evaluate the association between adverse childhood experiences (ACEs) and perceived life course body size trajectories.Methods A longitudinal study using data from the Canadian Longitudinal Study on Aging (CLSA) was conducted (n=11 830). Adults aged 49–93 were asked to recall eight ACEs and their perceived body size at ages 25, 45, 55, 65 and current using pictograms. …”
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Assessment of Health Risks in Wheat Crop Irrigated by Manka Canal, Dera Ghazi Khan, Pakistan by Muhammad Anwar ul Hassan, Sabiha Javied, Umair Riaz, Muneera A. Saleh, Khalid H. Alamer, Naila Siddique, Ambreen Aslam, Nabeela Noor, Qamar uz Zaman

“…The local community faces an elevated health risk index for both children and adults due to the consumption of wheat crop as HRI is greater than 1 for nonessential elements like Cd and Pb. …”
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MAO-B Polymorphism Associated with Progression in a Chinese Parkinson’s Disease Cohort but Not in the PPMI Cohort by Shi-Shuang Cui, Ling-Yu Wu, Gen Li, Juan-Juan Du, Pei Huang, Jin Liu, Yun Ling, Kang Ren, Zhong-Lue Chen, Sheng-Di Chen

“…The PARK16 haplotype was associated with Geriatric Depression Scale and the State-Trait Anxiety Inventory for Adults progression, and the SNCA haplotype was associated with the Hoehn-Yahr staging progression and motor PC1 progression. …”
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Effect of Rosiglitazone and Insulin Combination Therapy on Inflammation Parameters and Adipocytokine Levels in Patients with Type 1 DM by Metin Guclu, Ozen Oz Gul, Soner Cander, Oguzkaan Unal, Guven Ozkaya, Emre Sarandol, Canan Ersoy

“…Material and Methods. A total of 61 adults with type 1 DM were randomly and prospectively assigned in open-label fashion to take insulin and rosiglitazone 4 mg/day (n=30) or insulin alone (n=31) for a period of 18 weeks while undergoing insulin therapy without acute metabolic complications. …”
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