Decreased nitric oxide production is a novel therapeutic target for salt-induced nocturnal polyuria in aging by Takahiro Imanaka, Kentaro Takezawa, Yuma Kujime, Hiroaki Kitakaze, Go Tsujimura, Sohei Kuribayashi, Yosuke Sekii, Norichika Ueda, Shinichiro Fukuhara, Hiroshi Kiuchi, Hiromitsu Negoro, Norio Nonomura

“…In summary, increasing nitric oxide production may serve as a treatment method for salt-induced nocturnal polyuria in older adults.…”
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Epidemiology of snake bites and envenomations in the Bofidji Group – West, Equateur Province, Democratic Republic of the Congo by Blaise Engomba Mokekola, Jean-Paul Koto-Te-Nyiwa Ngbolua, Guy Bayeli Ilumbe, Idrissa Zabo Assumani, Aristarque Mulonda, Monizi Mawunu, Gires Mboyo Engomba, Colette Ashande Masengo, Godefroid Libono Ekamba

“…Results Snakebites were most prevalent among working-age adults, with women being disproportionately affected. …”
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Epidemiology of urinary tract infections in the Middle East and North Africa, 1990–2021 by Fatemeh Amiri, Saeid Safiri, Reza Aletaha, Mark J. M. Sullman, Kamaleddin Hassanzadeh, Ali-Asghar Kolahi, Shahnam Arshi

“…The DALY rate was 41.3 per 100,000 (95% UIs: 36.1–47.2), which was highest among older adults, reaching a peak in the 80–89 age range, and increasing with age, particularly from the 50 + age groups. …”
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Predicting the Health‐Promoting Lifestyle Profile of Pregnant Women Based on Their Health Literacy Levels: A Cross‐Sectional Study by Nastaran Rafat, Fatemeh Bakouei, Hajar Adib‐Rad, Hossein‐Ali Nikbakht, Sareh Bakouei

“…Methods This study surveyed 308 pregnant women in 2022 using questionnaires, including the Health Promoting Lifestyle Profile II (HPLP II) and the Health Literacy for Iranian Adults (HELIA). Descriptive and inferential statistics were employed to analyse the data by IBM SPSS 23.0 statistics package program. …”
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Occurrence and Assessment of Human Exposure to Microplastic Particles in Bottled Water From Southwest, Nigeria by Oluwatosin Shokunbi, Ebunoluwa Akinbile, David Jegede, Oluwawapelumi Oyedele, Olutayo Shokunbi

“…The concentrations of MPs in the bottled water were strongly correlated (r = 0.789, P < 0.01) with the pH of the water samples. Adults had an estimated EDI of 0.31 to 0.66 particles/kg bw/day, while children’s EDI ranged from 1.13 to 2.36 particles/kg bw/day. …”
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Transcranial brain atlas based on photon measurement density function in a triple-parameter standard channel space by Lijiang Wei, Yang Zhao, Farui Liu, Yuanyuan Chen, Yilong Xu, Zheng Li, Chaozhe Zhu

“…To overcome these limitations, this study proposes a continuous standard channel space for fNIRS and constructs a PMDF-based transcranial brain atlas (PMDF-TBA) by calculating PMDFs using MRI data from 48 adults. The PMDF-TBA contains group-averaged sensitivities of channels to gray matter and brain regions as defined in 3 atlases: Brodmann, AAL2, and LPBA40. …”
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Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study by Yuan-Zhuo Du, Jia-Qing Yang, Ji-Ming Yao, Chi-Teng Zhang, Yi-Fu Liu

“…This study explores the relationship of the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) with the risk of kidney stones in U.S. adults.MethodsThe analysis involved 24,532 participants with available NHR and kidney stone data from the 2007–2018 NHANES period. …”
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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials by Myra Happe, Amelia R. Hofstetter, Jing Wang, Galina V. Yamshchikov, LaSonji A. Holman, Laura Novik, Larisa Strom, Francis Kiweewa, Salim Wakabi, Monica Millard, Colleen F. Kelley, Sarah Kabbani, Srilatha Edupuganti, Allison Beck, Florence Kaltovich, Tamar Murray, Susanna Tsukerman, Derick Carr, Carl Ashman, Daphne A. Stanley, Aurélie Ploquin, Robert T. Bailer, Richard Schwartz, Fatim Cham, Allan Tindikahwa, Zonghui Hu, Ingelise J. Gordon, Nadine Rouphael, Katherine V. Houser, Emily E. Coates, Barney S. Graham, Richard A. Koup, John R. Mascola, Nancy J. Sullivan, Merlin L. Robb, Julie A. Ake, Kirsten E. Lyke, Mark J. Mulligan, Julie E. Ledgerwood, Hannah Kibuuka, the VRC 208 and RV 422 study team

“…We investigated the safety and immunogenicity of a heterologous prime-boost regimen involving a chimpanzee adenovirus 3 vectored Ebola vaccine [either monovalent (cAd3-EBOZ) or bivalent (cAd3-EBO)] prime followed by a recombinant modified vaccinia virus Ankara EBOV vaccine (MVA-EbolaZ) boost in two phase 1/1b randomized open-label clinical trials in healthy adults in the United States (US) and Uganda (UG). …”
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Scaling up of parenting support to prevent violence against children in Tanzania: insights from policymakers and service providers by Sabine van Tuyll van Serooskereken Rakotomalala, Kija Nyalali, Joyce Wamoyi, Onduru Gervas Onduru, Gerry Mshana, F. Marijn Stok, Mara A. Yerkes, John B. F. De Wit

“…Current factors hindering the scale-up include the lack of a common understanding of what evidence-based parenting programmes entail, inadequate provision of human and financial capital to implement the programmes using community resources and deeply engrained social norms around adultism and gender. Conclusion Daly’s analytical framework allowed us to examine barriers and facilitators to scale-up the provision of parenting support to prevent violence against children, based on the viewpoints of policymakers and service providers. …”
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Impact of synthetic insecticides on the life table parameters of Trichogramma chilonis under laboratory conditions by Muhammad Salim, Arsalan Arif, Muhammad Ayaz, Ahmad Ur Rahman Saljoqi, Ayhan Gökçe, Haroon Khan, Shahid Sattar, Bashir Ahmad, Shah Alam Khan

“…The results showed that the insecticides Imidacloprid and Chlorantraniliprole led to low mean fecundity, minimum number of male and female adults emergence and prolonged the total pre-oviposition period of T. chilonis as compared to Bifenthrin and Novaluron. …”
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Playful brains: a possible neurobiological pathway to cognitive health in aging by Yulia Golland, Yulia Golland, Boaz M. Ben-David, Boaz M. Ben-David, Boaz M. Ben-David, Mara Mather, Mara Mather, Mara Mather, Shoshi Keisari, Shoshi Keisari, Shoshi Keisari

“…Importantly, the collaborative and safe environment of playfulness transforms this uncertainty-driven noradrenergic activation into an engaging and rewarding experience, enhancing focus, positive affect, and flexibility. In older adults, where LC-NA functionality may decline with age, social playfulness could counteract cognitive decline by upregulating this system. …”
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High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis by Soon Sang Park, Tae Hoon Roh, Yoshiaki Tanaka, Young Hwa Kim, So Hyun Park, Tae-Gyu Kim, So Yeong Eom, Tae Jun Park, In-Hyun Park, Se-Hyuk Kim, Jang-Hee Kim

“…Glioblastoma, isocitrate dehydrogenase (IDH)-wildtype (GBM), is the most malignant brain tumor in adults, with limited therapeutic intervention. Previous studies have identified a few prognostic markers for GBM, including the methylation status of O6-methylguanine-DNA methyltransferase (MGMT) promoter, TERT promoter mutation, EGFR amplification, and CDKN2A/2B deletion. …”
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Efficacy of Wii-Fit on Static and Dynamic Balance in Community Dwelling Older Veterans: A Randomized Controlled Pilot Trial by Kalpana P. Padala, Prasad R. Padala, Shelly Y. Lensing, Richard A. Dennis, Melinda M. Bopp, Christopher M. Parkes, Mark K. Garrison, Patricia M. Dubbert, Paula K. Roberson, Dennis H. Sullivan

“…Balance problems are well-established modifiable risk factors for falls, which are common in older adults. The objective of this study was to establish the efficacy of a Wii-Fit interactive video-game-led physical exercise program to improve balance in older Veterans. …”
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Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana by Jacob Plange-Rhule, Sally M. Kerry, John B. Eastwood, Frank B. Micah, Sampson Antwi, Francesco P. Cappuccio

“…Weight, height, BP, and whole blood indices of viscosity (Hb, haematocrit, RBC count, and MCV) were measured in 921 adults (340 men, 581 women; aged 40–75) in 12 communities in Ghana. …”
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Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus by Shreya Mukhopadhyay, Ioannis Manolaridis, Christopher Warren, Aimin Tang, Gregory O’Donnell, Bin Luo, Ryan P. Staupe, Kalpit A. Vora, Zhifeng Chen

“…<b>Background/Objectives:</b> The respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children and adults. With nearly everyone infected by the age of five, there is an opportunity to develop booster vaccines that enhance B-cell immunity, promoting potent and broadly neutralizing antibodies. …”
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Outcomes of anterior cruciate ligament reconstruction surgery from private and public healthcare services in AustraliaKey points by Thomas J. West, Andrea M. Bruder, Kay M. Crossley, Michael A. Girdwood, Laura K. To, Jamon L. Couch, Mark J. Scholes, Sebastian C.S. Evans, Melissa J. Haberfield, Christian J. Barton, Ewa M. Roos, Alysha De Livera, Adam G. Culvenor

“…Conclusions: Australian young adults who underwent ACLR using private healthcare (compared to public healthcare) services reported better knee-related QoL post-operatively in this cross-sectional cohort. …”
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Patient and Physician Satisfaction with Analgesic Treatment: Findings from the Analgesic Treatment for Cancer Pain in Southeast Asia (ACE) Study by Dang Huy Quoc Thinh, Wimonrat Sriraj, Marzida Mansor, Kian Hian Tan, Cosphiadi Irawan, Johan Kurnianda, Yen Phi Nguyen, Annielyn Ong-Cornel, Yacine Hadjiat, Hanlim Moon, Francis O. Javier

“…This cross-sectional observational study involved 465 adults prescribed analgesics for cancer-related pain from 22 sites across Indonesia, Malaysia, Philippines, Singapore, Thailand, and Vietnam. …”
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Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study by Farshad Teymoori, Mahdi Akbarzadeh, Niloufar Saber, Mitra Kazemi Jahromi, Ebrahim Mokhtari, Parisa Riahi, Hossein Farhadnejad, Hamid Ahmadirad, Asiyeh Sadat Zahedi, Sajedeh Masjoudi, Danial Habibi, Maryam Zarkesh, Mohammadreza Vafa, Parvin Mirmiran, Maryam S. Daneshpour, Fereidoun Azizi

“…Our first analysis was conducted on adults (n = 748) who had four complete dietary and familial data on the third to sixth surveys of the Tehran Lipid and Glucose Study. …”
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Impaired Growth during Childhood in Patients with Primary Ciliary Dyskinesia by Tamara Svobodová, Jana Djakow, Daniela Zemková, Adam Cipra, Petr Pohunek, Jan Lebl

“…We analyzed longitudinal data on body length/height and body mass index (BMI) for 29 children and young adults with PCD aging 1.5–24 years (median, 14.5) who had been diagnosed at the age of 0.5–17 years (median, 8). …”
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Application of optical coherence tomography angiography to study retinal and choroidal vascular changes in patients with first-time coronary artery stenosis by Rongrong Guan, Shuyan Qin, Yezhu Chi, Zhen Tang, Haiyang Liu

“…Methods: A total of 100 subjects were enrolled in this study and divided into two groups: the observation group consisted of 50 patients with angina who were first diagnosed with coronary artery stenosis, and the control group consisted of 50 healthy adults without angina symptoms. All of the subjects underwent OCTA to investigate changes in retinochoroidal vessel density in patients with a first diagnosis of coronary artery stenosis. …”
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