Sex-Specific Differences in the Pathophysiology of Hypertension by Hannah Zhang, Pawan K. Singal, Amir Ravandi, Inna Rabinovich-Nikitin

“…Hypertension is one of the most common comorbidities in cardiometabolic diseases, affecting nearly one third of adults. As a result, its pathophysiological mechanisms have been studied extensively and are focused around pressure natriuresis, the renin–angiotensin system (RAS), the sympathetic nervous system, oxidative stress, and endothelial dysfunction. …”
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Triglycerides mediate the relationships of per- and poly-fluoroalkyl substance (PFAS) exposure with nonalcoholic fatty liver disease (NAFLD) risk in US participants by Wenying Qiao, Jiashuo Li, Lijia Luo, Wenjuan Peng, Xi Wang, Ronghua Jin, Junnan Li

“…Several clinical studies have investigated the associations between Per- and poly-fluoroalkyl substances (PFAS) compounds with the risk of NAFLD in general adults, but the mediating effect of triglycerides (TG) was remained unexplored. …”
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Reading between the lines: exploring the discriminative ability of the Short-Story Task in identifying autistic individuals within autism outpatient services by Irina Jarvers, Monika Sommer, Monika Sommer, Manuela Ullmann, Verena Simmel, Lore Blaas, Stefanie Gorski, Saskia Krüger-Lassen, Matthias Vogel, Berthold Langguth

“…While the short-story task (SST), a task measuring fiction-based mentalizing, has demonstrated promise in differentiating between autistic and non-autistic adults, its discriminative ability has not been investigated in a sample of individuals seeking autism diagnostics at outpatient services.MethodsThis study aimed to evaluate the utility of the SST in individuals seeking autism diagnostics between 2016 and 2022 at the Clinic and Polyclinic for Psychiatry & Psychotherapy of the University of Regensburg at medbo District Hospital Regensburg. …”
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The Polymorphism rs2725220 Is Associated with Hyperuricemia in the Korean Population by Jae Woong Sull, Seung-Ju Yang, Soriul Kim, Sun Ha Jee

“…This study clearly demonstrates that genetic variations in ABCG2 influence uric acid levels in Korean adults.…”
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The Bidimensional Model of Mental Health: an empirical approach in a general population sample by Manuel González, Mario González, Lastenia Hernández, Laureano Lorenzo

“…Methods: In a sample of 290 adults from the community, with 55.2% women and a mean age of 28.6 (Dt = 12.0). …”
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Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy by Julia Uffenorde, Mehran Hariri, Eleftherios Papalanis, Annika Staffas, Josefine Berg, Bo Stenerlöw, Hanna Berglund, Christer Malmberg, Diana Spiegelberg, Diana Spiegelberg

“…BackgroundGlioblastoma (GBM) is the deadliest form of brain cancer, impacting both adults and children, marked by exceptionally high morbidity and mortality rates, even with current standard treatments such as surgery, radiation therapy, and chemotherapy. …”
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No Modulatory Effects when Stimulating the Right Inferior Frontal Gyrus with Continuous 6 Hz tACS and tRNS on Response Inhibition: A Behavioral Study by Hannah Brauer, Navah Ester Kadish, Anya Pedersen, Michael Siniatchkin, Vera Moliadze

“…In this study, we intend to examine whether the boosting of theta activity by electrical stimulation over rIFG reduces the number of errors and the reaction times in a response inhibition task (Go/NoGo paradigm) during and after stimulation. 23 healthy right-handed adults participated in the study. In three separate sessions, theta tACS at 6 Hz, transcranial random noise (tRNS) as a second stimulation condition, and sham stimulation were applied for 20 minutes. …”
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‘‘Near Miss’’ Obstetric Cases: 4 Years Experience of a Tertiary Center by Hüseyin Cengiz, Cihan Kaya, Ramazan Ateş, Yusuf Ziya Yener, Murat Ekin, Levent Yaşar

“…RESULTS: During the study period, 6833 adults required ICU admission; 41 (0.60%) of them were obstetric patients. …”
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Explainable machine learning models for identifying mild cognitive impairment in older patients with chronic pain by Xiaoang Zhang, Yuping Liao, Daying Zhang, Weichen Liu, Zhijian Wang, Yaxin Jin, Shushu Chen, Jianmei Wei

“…Abstract Background Mild cognitive impairment (MCI) is prevalent in older adults with chronic pain, making early detection crucial for dementia prevention and healthy aging. …”
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A pilot randomized controlled study of integrated kidney palliative care and chronic kidney disease care implemented in a safety-net hospital: Protocol for a pilot study of feasibi... by Jennifer S. Scherer, Wenbo Wu, Chen Lyu, Keith S. Goldfeld, Abraham A. Brody, Joshua Chodosh, David Charytan

“…The inclusion criteria are adults 18 or older, who are either Spanish or English speakers, have an estimated Glomerular Filtration Rate (eGFR) of ≤30 mL/min/1.73 m2, and are receiving care at our safety net hospital. …”
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Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response by Michal Holub, Alžběta Stráníková, Pavel Chalupa, Simona Arientová, Kateřina Roubalová, Ondřej Beran

“…T cell responses to HSV-1 and HSV-2 native antigens and the expression of HLA-DR and CD38 molecules on circulating CD8+ T cells were analysed in adults with high frequency of GH recurrences (19 patients) and low frequency of GH recurrences (7 patients) and 12 HSV-2 seronegative healthy controls. …”
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Evaluating the Carcinogenic and Non-Carcinogenic Health Risks of Heavy Metals Contamination in Drinking Water, Vegetables, and Soil from Gilgit-Baltistan, Pakistan by Nafeesa Khatoon, Sartaj Ali, Azhar Hussain, Jia Huang, Zengli Yu, Hongyan Liu

“…The lifetime cancer risk (LCR) by drinking water for Cd, Cr, and Ni in Gilgit (0.0087, 0.55, and 0.0048) and Skardu (0.071, 0.21, and 0.014) indicated a considerable cancer risk (>1 × 10⁻⁴) for adults. The cancer risk for vegetable intake was observed within the safe limit, while LCR_ingetsion > LCR_dermal and LCR_inhalation for the soil samples in both regions. …”
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Bioelectrical Impedance and Dual-Energy X-Ray Absorptiometry Assessments of Changes in Body Composition Following Exercise in Patients with Type 2 Diabetes Mellitus by Masae Miyatani, Pearl Yang, Scott Thomas, B. Catharine Craven, Paul Oh

“…We aimed to compare the level of agreement between leg-to-leg bioelectrical impedance analysis (LBIA) and dual-energy X-ray absorptiometry (DXA) for assessing changes in body composition following exercise intervention among individuals with Type 2 diabetes mellitus (T2DM). Forty-four adults with T2DM, age 53.2±9.1 years; BMI 30.8±5.9 kg/m2 participated in a 6-month exercise program with pre and post intervention assessments of body composition. …”
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Schistosoma japonicum Infection in Treg-Specific USP21 Knockout Mice by Youxiang Zhang, De-Hui Xiong, Yangyang Li, Guina Xu, Baoxin Zhang, Yang Liu, Shan Zhang, Qing Huang, Simin Chen, Fansheng Zeng, Jingyi Guo, Bin Li, Zhiqiang Qin, Zuping Zhang

“…Using a murine model infected with Schistosoma japonicum, we observed that there were more cercariae developed into adults and more eggs deposited in the livers of the USP21fl/flFOXP3Cre (KO) mice. …”
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Comparison of sagittal measurements of cervical spine in spondylosis patients between Magnetic Resonance Imaging and Radiograph [version 1; peer review: 2 approved] by Rajagopal Kadavigere, Saikiran Pendem, Varsha R, Tancia Pires, Surbhi Gupta Aggarwal, Shailesh S Nayak, Priyanka -, Maria Nicolet

“…Background Cervical spondylosis is the common degenerative disease of the vertebrae in adults which can lead to change in sagittal alignment of cervical spine. …”
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Nurture-U student mental health longitudinal survey: a study protocol by Kate E Saunders, Samuel R Chamberlain, Jemima Dooley, Edward R Watkins, Liz Forty, Sarah Rees, Anne C Duffy, Anthony Quinn, Ellen Marshall, Lucy Dorey, Kevin A Matlock, Alexandra Newbold, Lucy J Robinson

“…Introduction University life represents a critical period for young adults, providing opportunities for personal growth and development of coping skills but also posing significant mental health challenges. …”
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The trend of suicide and self-harm in the Chinese population from 2018 to 2022 based on ambulance medical emergency cases: a retrospective study by Ruizhe Yang, Jinsu Zhou, Francis Manyori Bigambo, Wu Yan, Xu Wang, Haibo Yang

“…The study emphasizes the need for targeted prevention strategies, particularly focusing on drug-related suicides among adults and adolescents, as well as the prevalence of various self-harming behaviors.ConclusionTo reduce self-harm and suicide, interventions must be strengthened for women, who experience higher rates. …”
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Turkish suicide patterns: Longitudinal analysis of suicide trends in Turkiye (2000 -2022) by Ayhan Tabur, Feruza Turan Sonmez

“…These findings highlight the urgent need for targeted public health interventions in Turkiye, particularly for young adults and women. Emergency departments play a pivotal role in identifying at-risk individuals, emphasizing the importance of enhanced screening protocols and mental health assessments. …”
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Gamification Application for Promoting and Encouraging Physical Activity in the Elderly by Narmin Mohammed Noori, Awaz Naaman Saleem, Muhammed Anwar

“…Despite a growing body of research on this topic, there is still a lack of consensus regarding the nature and extent of older adults' knowledge and healthcare professionals about gamification applications and physical health outcomes among this demographic group. …”
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Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme—An In Vivo Safety, Persistence, and Efficacy Study by Jasmine L. King, Alain Valdivia, Shawn D. Hingtgen, S. Rahima Benhabbour

“…Background/Objectives: Glioblastoma multiforme (GBM) is the most common high-grade primary brain cancer in adults. Despite efforts to advance treatment, GBM remains treatment resistant and inevitably progresses after first-line therapy. …”
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