Bifidobacterium adolescentis-derived nicotinic acid improves host skeletal muscle mitochondrial function to ameliorate sarcopenia by Zeng Zhang, Quan Guo, Zhihan Yang, Yukai Sun, Shuaiming Jiang, Yangli He, Jiahe Li, Jiachao Zhang

“…Summary: Sarcopenia significantly diminishes quality of life and increases mortality risk in older adults. While the connection between the gut microbiome and muscle health is recognized, the underlying mechanisms are poorly understood. …”
Get full text

A Rare Case of Glioblastoma Multiforme with Osseous Metastases by Rubens Barros Costa, Ricardo Costa, Jason Kaplan, Marcelo Rocha Cruz, Hiral Shah, Maria Matsangou, Benedito Carneiro

“…Glioblastoma multiforme is the most common malignant primary central nervous system neoplasm in adults. It has a very aggressive natural history with a median overall survival estimated at 14.6 months despite multimodality treatment. …”
Get full text

Gesture sonification for enhancing agency: an exploratory study on healthy participants by Felix Schoeller, Felix Schoeller, Parham Ashur, Joseph Larralde, Clement Le Couedic, Rajeev Mylapalli, Karthikeyan Krishnanandan, Anna Ciaunica, Anna Ciaunica, Adam Linson, Mark Miller, Nicco Reggente, Vladimir Adrien, Vladimir Adrien

“…., wearable technology transforming body movements into sounds, to enhance proprioception, BA, and thus the SA.MethodsIn this within-subjects design, 17 healthy adults (mean age = 25.5 years) with varying dance expertise (novice, amateur, expert) improvised movements to match sounds with and without auditory feedback from motion sensors on wrists/ankles modulated by their gestures. …”
Get full text

Grinspan’s Syndrome: A Rare Case with Malignant Transformation by Numan Kökten, Lokman Uzun, Ayşe Serap Karadağ, Tülay Zenginkinet, M. Tayyar Kalcıoğlu

“…Oral lichen planus (OLP) is one of the common chronic inflammatory, noninfectious, and precancerous oral mucosal diseases that affect the stratified squamous epithelium in adults. Grinspan et al. reported an association of OLP with diabetes mellitus and vascular hypertension and called that Grinspan’s syndrome in 1966. …”
Get full text

Safety and immunogenicity in humans of enterotoxigenic Escherichia coli double mutant heat-labile toxin administered intradermally by Marcela F. Pasetti, Patricia L. Milletich, Jessica A. White, Jessica Butts, Rebecca C. Brady, Michelle D. Dickey, Cassandra Ballou, Nicole Maier, Marcelo B. Sztein, Shahida Baqar, A. Louis Bourgeois, David I. Bernstein

“…A Phase 1, double-blind, dose-escalation (0.1-2.0 µg) study was conducted to evaluate the safety and immunogenicity of double mutant heat-labile toxin LTR192G/L211A (dmLT) delivered intradermally (ID) to healthy adults. Subjects received up to three immunizations at three-week intervals. …”
Get full text

Spiradenoma: A Case Report and Review of the Literature by Jia-Ying Chang, Yen-Chang Chen, Dah-Ching Ding

“…<b>Background and Clinical Significance:</b> Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. <b>Case Presentation:</b> A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. …”
Get full text

Loading and Skeletal Development and Maintenance by P. Bergmann, J. J. Body, S. Boonen, Y. Boutsen, J. P. Devogelaer, S. Goemaere, J. Kaufman, J. Y. Reginster, S. Rozenberg

“…Exercise programs in adults and seniors have barely significant effects on bone mass and geometry at least at short term. …”
Get full text

Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report by Preema J. Mehta, Sherita Chapman, Annapurni Jayam-Trouth, Mohankumar Kurukumbi

“…Thus, we suggest a possible relationship between IDA and ischemic stroke in young adults. Considering IDA as one of the risk factors for ischemic stroke and treating with timely transfusions would be an important step one can take to prevent stroke.…”
Get full text

Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function: The Multiethnic Study of Athero... by Jennifer S. Anderson, Jennifer A. Nettleton, W. Gregory Hundley, Michael Y. Tsai, Lyn M. Steffen, Rozenn N. Lemaitre, David Siscovick, João Lima, Martin R. Prince, David Herrington

“…Associations of plasma phospholipid fatty acid levels (arachidonic acid, linoleic acid, eicosapentaenoic acid, docosahexaenoic acid (DHA), and alpha-linolenic acid) with cardiac magnetic resonance imaging measures of left ventricular (LV) mass, LV volume, ejection fraction, stroke volume, and aortic distensibility were investigated in 1,274 adults. Results. Results of multivariate analysis showed no statistically significant associations of plasma omega-6 or omega-3 levels with cardiac magnetic resonance imaging measures. …”
Get full text

Molecular Detection and Genotyping of Chlamydia psittaci in Captive Psittacines from Costa Rica by Jessica Sheleby-Elías, Ántony Solórzano-Morales, Juan José Romero-Zuñiga, Gaby Dolz

“…The positive samples belonged to birds presented at veterinary clinics; three of them were Ara macao and one Amazona ochrocephala. Three birds were adults; all positive birds showed no symptoms of illness and lived in homes with other birds, two in San José and two in Heredia. …”
Get full text

Hepatocellular Carcinoma with Both Fibrolamellar and Classical Components: An Unusual Morphological Pattern by Diana Castro-Villabón, Luis E. Barrera-Herrera, Paula A. Rodríguez-Urrego, Rachel Hudacko, Alonso Vera, Johanna Álvarez, Rafael Andrade, Rocío López

“…It is usually seen in young adults without underlying liver disease. Histologically, it shows large cells with abundant eosinophilic cytoplasm, large vesicular nuclei, prominent nucleoli, and lamellar type fibrosis. …”
Get full text

Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters by Nina Kemala Sari, Stepvia Stepvia, Muhana Fawwazy Ilyas, Siti Setiati, Siti Setiati, Kuntjoro Harimurti, Ika Fitriana

“…Aging-related laboratory biomarkers were defined as those indicating physiological aging processes.ResultsThe study revealed a significant association between handgrip strength and several aging-related laboratory parameters, including leukocyte count, absolute neutrophil count, absolute lymphocyte count, neutrophil/lymphocyte ratio, and erythrocyte sedimentation rate.DiscussionThese findings suggest that handgrip strength could serve as a cost-effective, non-invasive predictor of aging-related health status in older adults. Its practical utility highlights its potential for guiding health interventions targeting the elderly population.…”
Get full text

Clozapine-Induced Microseizures, Orofacial Dyskinesia, and Speech Dysfluency in an Adolescent with Treatment Resistant Early Onset Schizophrenia on Concurrent Lithium Therapy by Vivekananda Rachamallu, Ayman Haq, Michael M. Song, Manish Aligeti

“…In addition, numerous case reports have described clozapine-induced stuttering in adults. However, there has been only one previous case report describing it in the adolescent population. …”
Get full text

DETEC-ADHD: A Data-Driven Web App for Early ADHD Detection Using Machine Learning and Electroencephalography by Ismael Santarrosa-López, Giner Alor-Hernández, Maritza Bustos-López, Jonathan Hernández-Capistrán, Laura Nely Sánchez-Morales, José Luis Sánchez-Cervantes, Humberto Marín-Vega

“…The case studies demonstrated DETEC-ADHD’s effectiveness, achieving 100% accuracy in children and 90% in adults. By integrating diverse data sources with real-time EEG analysis, DETEC-ADHD provides a scalable, cost-effective, and accessible solution for ADHD detection and subtype identification, addressing diagnostic challenges and supporting healthcare providers, particularly in resource-limited environments.…”
Get full text

The Dader Method in pharmaceutical attention of hypertensive patients at Pontal do Araguaia/MT, Brazil by Maria Fernanda Spegiorin Sala Brune, Ellen Eliane Ferreira, Carlos Kusano Bucalen Ferrari

“…The objective of this study was to investigate the control of hypertension in adults according to the Dader Method of Pharmacotherapy Monitoring. …”
Get full text

The mediating role of peritraumatic stress in the relationship between childhood psychological maltreatment and optimism and pessimism among earthquake survivors in Turkey by Zafer Güney ÇAĞIŞ, İslam AKÇE, Izaddin Ahmad AZİZ, Amelia RIZZO, Gabriella NUCERA, Nicola BRAGAZZI, Lukasz SZARPAK, Francesco CHIRICO, Arash ZIAPOUR, Mehmet Emin ŞAKAR, Şoreş Hakı ÇELİK, Murat YILDIRIM

“…Methods: Using a snowball sampling technique with a cross-sectional research design, the sample comprised 311 adults who survived earthquake survivors in Turkey. …”
Get full text

Cecum Volvulus. Presentation of a Case and Literature Review by Ernesto Pérez Quintana, José Alberto Puerto Lorenzo, Lidia Torres Aja

“…Cecum volvulus is a rare clinical condition and represents only between 2 and 3 % of cases of intestinal occlusion in adults. We present the case of a 56-year-old female patient with a history of high blood pressure, diabetes mellitus and chronic constipation, who attended the surgery ward at the Dr. …”
Get full text

Cardiovascular Risk Factors in a Suburban Community in Nigeria by Titilope Modupe Dokunmu, Omolara Faith Yakubu, Abiodun Humphrey Adebayo, Grace Iyabo Olasehinde, Shalom Nwodo Chinedu

“…This study evaluated blood pressure (BP) in healthy adults to determine their risk of developing hypertension and to reduce associated morbidity of the disease. …”
Get full text

Early growth response 1 transcription factor and its context-dependent functions in glioblastoma by Saleh Rasras, Esma’il Akade, Seyed Ehsan Mohammadianinejad, Maedeh Barahman, Mohammad Bahadoram

“…Glioblastoma is the most aggressive form of primary brain tumour in adults. This tumour employs numerous transcription factors to advance and sustain its progression. …”
Get full text

Rhinitis medicamentosa: a nationwide survey of Canadian otolaryngologists by James Fowler, Christopher J. Chin, Emad Massoud

“…This condition commonly affects young adults and treatment is not trivial. We aimed to survey Canadian Otolaryngologists to determine practice patterns and their opinions regarding this under-studied condition. …”
Get full text