Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis by Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

“…This shift in Cdx2 binding facilitates Ctcf and Hnf4 recruitment, establishing super-enhancers during development and homeostatic enhancers in adult cells, respectively. Induced DNA methylation in adult mouse epithelium or cultured cells recruits Cdx2 to developmental targets, promoting corecruitment of partner transcription factors. …”
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Interactive Crossword Puzzles as an Adjunct Tool in Teaching Undergraduate Dental Students by Abubaker Qutieshat, Nutayla Al-Harthy, Gurdeep Singh, Viresh Chopra, Rayhana Aouididi, Rayan Arfaoui, Sapna Dileesh, Ahmed Alsadoon, Omaima Al-Nadhiri, Shima Al-Busaidi, Sumaiya Al-Rashdi, Mohammad S Alrashdan

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Nouvelles données sur les caractéristiques morphologiques immatures du crâne chez les Homo erectus asiatiques by Antoine Balzeau

“…It is critical to be able to recognize the juvenile specimens within the fossil record in order to determine the adult variability of the different taxa and to approach their ontogenetic and phylogenetic characteristics. …”
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Stress during Lactation Induces Insulin Resistance Associated with an Increase in Type 1 Cannabinoid Receptors in Liver and Adipose Tissue by Liza Fonseca, Valeska Castillo, Carolina Aguirre, Paulo Silva, Ana M. Ronco, Miguel Llanos

“…Adult NS animals also had low plasmatic adiponectin and, although nonsignificant, had a sustained trend to a greater LPL activity associated with epididymal fat. …”
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Famine Exposure in Early Life and Risk of Metabolic Syndrome in Adulthood: Comparisons of Different Metabolic Syndrome Definitions by Feng Ning, Jie Ren, Xin Song, Dong Zhang, Li Liu, Lei Zhang, Jianping Sun, Dongfeng Zhang, Zengchang Pang, Qing Qiao, on behalf of Qingdao Diabetes Prevention Program

“…Two cross-sectional surveys involving randomly selected Chinese adults aged 35–74 years in the Qingdao area were conducted. …”
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Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice: Effects of Deprived Rearing and Voluntary Running by Andrea T. U. Schaefers, Keren Grafen, Gertraud Teuchert-Noodt, York Winter

“…We examined if a similar epigenetic effect of rearing environment on adult neuroplastic responses can be found in mice (Mus musculus). …”
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Emerging Stem Cell Therapies: Treatment, Safety, and Biology by Joel Sng, Thomas Lufkin

“…There is also increasing interest in the therapeutic potential of other adult stem cells such as neural, mammary, intestinal, inner ear, and testicular stem cells. …”
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Mesenchymal Stem Cells Isolated from Adipose and Other Tissues: Basic Biological Properties and Clinical Applications by Hakan Orbay, Morikuni Tobita, Hiroshi Mizuno

“…Mesenchymal stem cells (MSCs) are adult stem cells that were initially isolated from bone marrow. …”
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Determinants of Preeclampsia among Women Attending Delivery Services in Public Hospitals of Central Tigray, Northern Ethiopia: A Case-Control Study by Teklehaimanot Gereziher Haile, Nega Assefa, Tadesse Alemayehu, Teklewoini Mariye, Gebreamlak Gebremedhn Geberemeskel, Degena Bahrey, Guesh Mebrahtom, Biniyam Demisse, Hailemikael Gebrekidan, Tamirat Getachew

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TLR4 Inhibition Attenuated LPS‐Induced Proinflammatory Signaling and Cytokine Release in Mouse Hearts and Cardiomyocytes by Christine W. Wiger, Trine Ranheim, Henriette Arnesen, Jarle Vaage, Søren E. Pischke, Arne Yndestad, Kåre‐Olav Stensløkken, May‐Kristin Torp

“…LPS activated the nuclear‐factor κ‐light‐chain‐enhancer of activated B cells signaling pathway (NF‐κB) in primary adult cardiomyocytes. Moreover, TLR4 inhibition reduced LPS‐induced mRNA expression and release of IL‐6 in primary adult cardiomyocytes. …”
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Ascending Aorta Diameter Changes after Aortic Valve Replacement in Elderly Patients with Aortic Valve Stenosis by Jiamiao Gong, Kang An, Hongyuan Lin, Jianfeng Hou

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Methotrexate for the Treatment of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation by Amr Nassar, Ghada Elgohary, Tusneem Elhassan, Zubeir Nurgat, Said Y. Mohamed, Mahmoud Aljurf

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Frequency and Prognostic Relevance of FLT3 Mutations in Saudi Acute Myeloid Leukemia Patients by Ghaleb Elyamany, Mohammad Awad, Kamal Fadalla, Mohamed Albalawi, Mohammad Al Shahrani, Abdulaziz Al Abdulaaly

“…The frequency of FLT3 mutations in our study (18.56%) was lower than many of the reported studies, FLT3-ITD mutations were observed in 14.4%, and FLT3-TKD in 4.1%, of 97 newly diagnosed AML patients (82 adult and 15 pediatric). Our data show significant increase of FLT3 mutations in male more than female (13 male, 5 female). …”
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Measles neutralising antibody levels in patients receiving intravenous immunoglobulin treatment - a sub-analysis of a randomized, cross-over bioequivalence trial. by Vatsala Rajendram, Martyn Paddick, John More

“…Eligible adult patients received five infusions of Gammaplex® 5% followed by five infusions of Gammaplex® 10%, or vice versa, on either a 21- or 28-day dosing regimen. …”
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Epidemiological analysis of Leishmaniasis prevalence in Pakistan during 2016-2023 by R. Uppal, U. Saeed, M. E. Khattak, A. A. Khan, M. R. Uppal, Z. Z. Piracha, M. N. Khan, D. Shaikh, U. Tariq, A. R. Mahmood, S. S. Ali, B. Muhammad, M. N. Tariq, S. S. Gilani, D. U. Ozsahin, B. Uzun, I. Ozsahin

“…Initially, from 2016 to 2020, a positivity rate of 27% was observed exclusively among pediatric patients in Islamabad, with no adult cases. Subsequently, from 2017 to 2022, the positivity rate increased to 42%, affecting both pediatric and adult populations in Islamabad, Rawalpindi, and Swat. …”
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Effects of Macromolecular Crowding on Human Adipose Stem Cell Culture in Fetal Bovine Serum, Human Serum, and Defined Xeno-Free/Serum-Free Conditions by Mimmi Patrikoski, Michelle Hui Ching Lee, Laura Mäkinen, Xiu Min Ang, Bettina Mannerström, Michael Raghunath, Susanna Miettinen

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ZD7288 Enhances Long-Term Depression at Early Postnatal Medial Perforant Path-Granule Cell Synapses by Xiati Guli, Tursonjan Tokay, Marco Rohde, Roland A. Bender, Rüdiger Köhling, Timo Kirschstein

“…HCN channels in adult tissue hence lose their modulatory effect. …”
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Quality of Life and Events in the First Year of Life. Results from the Prospective Copenhagen Birth Cohort 1959?61 by Søren Ventegodt, Trine Flensborg-Madsen, Niels Jørgen Andersen, Mohammed Morad, Joav Merrick

“…adult child? 31–33 years later. The results showed that a mother's attitude towards her pregnancy, unsuccessful abortions, and/or institutionalization left a permanent trace on the child, since these children, as adults, have a quality of life 3% below the average. …”
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Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats by Mirko Rehberg, Timo Kirschstein, Xiati Guli, Steffen Müller, Marco Rohde, Denise Franz, Tursonjan Tokay, Rüdiger Köhling

“…Spatial memory training significantly reduced subsequent CA1-LTP in vitro in the adolescent control group yet enhanced CA1-LTP in the adult pilocarpine-treated group. Such training in the adolescent pilocarpine-treated and adult control groups resulted in intermediate changes. …”
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Perspectives for Clinical Translation of Adipose Stromal/Stem Cells by Mimmi Patrikoski, Bettina Mannerström, Susanna Miettinen

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