Prediction of CD4 T-Lymphocyte Count Using WHO Clinical Staging among ART-Naïve HIV-Infected Adolescents and Adults in Northern Ethiopia: A Retrospective Study by Abraham Desta Aregay, Kibriti Mehari Kidane, Asfawosen Berhe Aregay, Kiros Ajemu Fenta, Ataklti Gebretsadik Woldegebriel, Hagos Godefay, Tewolde Wubayehu Woldearegay

“…However, correlation between CD4 count and WHO clinical staging is not known in an Ethiopian setting, and hence, the main aim of this study was to assess predictability of CD4 T-lymphocyte count using WHO clinical staging among ART-naïve HIV-infected adolescents and adults in northern Ethiopia. Methods. A retrospective cross-sectional study was done in the Tigray Region, Ethiopia, from April 2015 to January 2019 from a secondary database of 19525 HIV-infected patients on antiretroviral treatment. …”
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Life threatening scorpion sting on adult complicated by: acute toxic myocarditis, cardiogenic shock, pulmonary edema, acute kidney injury and toxic hepatitis: a case report by Filmon Tesfay, Okbu Frezgi, Meron Asheber, Lidia Mussie

“…Abstract Background Occurrence of life-threatening scorpion sting in adults is a rare entity compared with children. Different cases of organ failure following scorpion sting have been reported but complications, such as acute toxic myocarditis, cardiogenic shock, pulmonary edema, acute kidney injury and toxic hepatitis occurring simultaneously in adult patients is exceedingly rare with no prior documented similar report. …”
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Use of screens, books and adults' interactions on toddler's language and motor skills: A cross-cultural study among 19 Latin American countries from different SES. by Lucas G Gago-Galvagno, Angel M Elgier, Angel J Tabullo, Edson J Huaire-Inacio, Angela M Herrera-Alvarez, Carmen Zambrano-Villalba, Frania R López, Emmanuel Herrera-González, Olivia Morán-Núñez, Neyra J Ochoa-Vega, Chrissie Ferreira de Carvalho, Rosario Spencer, Juan José Giraldo-Huertas, Perla Del Carpio, Erika Robles, Carla Fernández, Silvia Requena, Pilar Rodríguez, Yoysy Rondón, Alexis L Ruiz, Ada Tibisay-Echenique, Gris Hidalgo, Carlos R Hernández, Mirna Lacayo, Esther Angeriz, Gabriela Etchebehere, Fernando José Mena, Delia Magaña de Ávila, Susana C Azzollini, Stephanie E Miller

“…Also, most of the screen time was shared with an adult. These results were consistent across parent-reported SES and nationality. …”
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Alteration in Oxidative Stress Enzymes and Proteins by Datura metel Stramonium Hydroethanolic Root Extract Promotes Hippocampus and Cerebral Cortex Neurons Damage in Adult Sprague Dawley Rats by oboma YI, Eberechukwu GC

“…Yibala Ibor oboma,1,2 God’sman C Eberechukwu1,3 1Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University Wilberforce Island Bayelsa State, Amassoma, Nigeria; 2Department of Medical Laboratory Science, School of Allied Health Sciences, Kampala International University, Ishaka Municipal, Uganda; 3Department of Histopathology and Cytopathology, Faculty of Medical Laboratory Science, Federal University, Otuoke, Bayelsa State, NigeriaCorrespondence: Yibala Ibor oboma, Department of Medical Laboratory Science, School of Allied Health Sciences, Kampala International University, Western Campus, Bushenyi District, Ishaka Municipal, Uganda, Tel +256740059020, Email yibaaoboma@kiu.ac.ugBackground: Datura metel is reported to induce hallucinations and mental disorders.Objective: This study investigates the neurotoxic effects of Datura metel stramonium hydroethanolic root extract on the hippocampus and cerebral cortex of adult rats using biochemical, histological and immunohistochemical techniques.Methodology: Twenty five adult rats were assigned to 5 groups (n = 5 each). …”
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Effectiveness of Different Intervention Modes in Lifestyle Intervention for the Prevention of Type 2 Diabetes and the Reversion to Normoglycemia in Adults With Prediabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yachen Wang, Xin Chai, Yueqing Wang, Xuejun Yin, Xinying Huang, Qiuhong Gong, Juan Zhang, Ruitai Shao, Guangwei Li

“…This review included randomized controlled trials (RCTs) that studied the effectiveness of lifestyle interventions in adults with prediabetes. The overall intervention effect was synthesized using a random-effects model. …”
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The first experience with sodium‐glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure by Anastasia D. Egorova, Marieke Nederend, Laurens F. Tops, Hubert W. Vliegen, Monique R.M. Jongbloed, Philippine Kiès

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Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis of randomized controlled studies by Yining Lu, Julien S. Baker, Shanshan Ying, Yichen Lu

“…The inclusion criteria required glucose and insulin resistance markers to be evaluated pre- and post-intervention among adults who were not trained athletes.ResultsAs a result, twenty studies were included, and meta-analyses were conducted using sixteen studies employing HIIT protocols. …”
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Association of a novel nutritional index with cognitive impairment in middle-aged and elderly Chinese adults: a cross-sectional analysis from the China Health and Retirement Longitudinal Study by Guotao Liu, Jianyuan Zhang

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Dietary intake of tomato and lycopene, blood levels of lycopene, and risk of total and specific cancers in adults: a systematic review and dose–response meta-analysis of prospective cohort studies by Arghavan Balali, Kimia Fathzadeh, Gholamreza Askari, Omid Sadeghi, Omid Sadeghi

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Socioeconomic status moderate the relationship between mental health literacy, social participation, and active aging among Chinese older adults: evidence from a moderated network analysis by Yalian Huang, Aibao Zhou, Ping Tang, Xufeng Ma

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A Comparison of Urine Dilution Ability between Adult Dominant Polycystic Kidney Disease, Other Chronic Kidney Diseases, and Healthy Control Subjects: A Case-Control Study by M. H. Malmberg, F. H. Mose, E. B. Pedersen, J. N. Bech

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CIHR Canadian HIV Trials Network Co-Infection and Concurrent Diseases Core: Updated Canadian Guidelines for the Treatment of Hepatitis C Infection in HIV-hepatitis C Coinfected Adults by Mark Hull, Stephen Shafran, Alice Tseng, Pierre Giguère, Marina B Klein, Curtis Cooper

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Effect of Moderate Red Meat Intake Compared With Plant-Based Meat Alternative on Psychological Well-Being: A 10-Wk Cluster Randomized Intervention in Healthy Young Adults by Tamlin S Conner, Nicola A Gillies, Anna Worthington, Emma N Bermingham, Jillian J Haszard, Scott O Knowles, Daniel R Bernstein, David Cameron-Smith, Andrea J Braakhuis

“…Eighty healthy omnivorous young adults were clustered as 40 cohabitating household pairs. …”
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Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C by Xi-yu Liu, Hong Li

“…Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. …”
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Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and Functional Foods in Treatment and Prevention of Gastroenterological Diseases in Children and Adults by V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, S. A. Alekseenko, A. V. Gorelov, I. N. Zakharova, O. Yu. Zolnikova, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammayev, E. A. Poluektova, A. S. Trukhmanov, D. V. Usenko, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, I. V. Berezhnaya, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, S. V. Nikolaeva, N. G. Sugyan, A. I. Ulyanin

“…The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and general internists to advance the treatment and prevention of gastroenterological diseases in adults and children in therapies with probiotics, prebiotics, synbiotics and their enriched functional foods.Key points. …”
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Personalized screening strategies for TP53 R337H carriers: a retrospective cohort study of tumor spectrum in Li-Fraumeni syndrome adult carriersResearch in context by Pedro A.F. Galante, Gabriela D.A. Guardia, Janina Pisani, Renata L. Sandoval, Mateus C. Barros-Filho, Ana Carolina Leite Vieira Costa Gifoni, Diogo F.C. Patrão, Patricia Ashton-Prolla, Vitor Fiorin de Vasconcellos, Claire Freycon, Arnold Levine, Pierre Hainaut, Maria Isabel Achatz

“…Here, we assessed tumor patterns and temporal trends, cancer risk, and sex differences of adult R337H carriers and carriers of other LFS-associated variants. …”
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Determinants of Active Tuberculosis Occurrences after ART Initiation among Adult HIV-Positive Clients in West Showa Zone Public Hospitals, Ethiopia: A Case-Control Study by Gerbaba Guta Nugus, Mergitu Eliyas Irena

“…A total of 406 participants (203 cases and 203 controls) were included in the study. Cases were adult HIV patients who developed tuberculosis after ART initiation while controls were adult HIV patients who did not develop tuberculosis after ART initiation. …”
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Relationships between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults: A study based on the China health and retirement longitudinal study (CHARLS) by Yixuan Ma, Xinze Wu, Yinjiao Zhao, Weihao Hong, Yisheng Luan, Peiyu Song, Bing Zhang

“…This study aims to analyze the interaction between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults, providing a theoretical basis for better prevention of cognitive decline. …”
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Impact of <i>Saccharomyces cerevisiae</i> DSM 34246 (Canobios-BL) var. <i>boulardii</i> Supplementation on Nutritional Status and Fecal Parameters in Healthy Breeding Adult Cats by Nicolò Lonigro, Elisa Martello, Natascia Bruni, Mauro Bigliati, Annalisa Costale, Ilaria Lippi, Giorgia Meineri, Francesca Perondi

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Overall quit in triple users of conventional cigarette, e-cigarette and heated tobacco product among healthy adults: a Korea Medical Institute health check-up study by Sun Ha Jee, Heejin Kimm, Keum Ji Jung, Hye Won Yun

“…We aimed to analyse overall quit in triple users of CC, EC and HTP among healthy adults.Methods A questionnaire was conducted on 89 360 adults who visited the Korea Medical Institute health check-ups in Seoul, Korea, from May 2018 to September 2019. …”
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