Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…Pheochromocytomas (PCC) are rare tumors that arise in chromaffin tissue of the adrenal gland. PCC are frequently inherited through predisposing mutations in genes such as the von Hippel-Lindau (VHL) tumor suppressor. …”
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A Peculiar Cause of Shock: Analysing Two Clinical Cases by João Oliveira, Alberto Costa-Silva, Luís Vale, Daniel Costa, Rui Almeida-Pinto, Carlos Martins-Silva, Tiago Antunes-Lopes, João Silva

“…Additionally, and incidentally, it revealed a 60 mm nodule on the right adrenal gland. Piperacillin/tazobactam was started immediately, and the patient was submitted to urgent upper urinary tract drainage. …”
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Immunohistochemistry for (Pro)renin Receptor in Humans by Satoshi Morimoto, Noriko Morishima, Daisuke Watanabe, Yoichiro Kato, Noriyuki Shibata, Atsuhiro Ichihara

“…It was observed in thyroid follicular epithelial cells, hepatic cells, pancreatic duct epithelial cells, zona glomerulosa and zona reticularis of the cortex and medulla of the adrenal gland, proximal and distal tubules and collecting ducts of the kidney, cardiomyocytes, and skeletal muscle cells. …”
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False Positive Radioiodinated Metaiodobenzylguanidine (123I-MIBG) Uptake in Undifferentiated Adrenal Malignant Tumor by Hee Soo Jung, Seok Jun Moon, Yun Mi Kim, Hye Rim Kang, Seok Mo Lee, Soo Jin Jung, Seok Jin Choi, Tae Kyoon Kim, Min Jeong Kwon, Jeong Hyun Park, Soon Hee Lee

“…Abdominal computed tomography (CT) revealed a heterogeneous left adrenal mass 6 cm in diameter; following hormone testing, 123I-MIBG scintigraphy was performed to determine the presence of pheochromocytoma, which confirmed eccentric uptake by a large left adrenal gland mass. Chest CT and PET-CT confirmed metastatic lymphadenopathy; therefore, endobronchial ultrasound transbronchial needle aspiration was performed. …”
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An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor by Sanjivini V. Jacob, John D. Reith, Angerika Y. Kojima, William D. Williams, Chen Liu, Lizette Vila Duckworth

“…PET/CT scan revealed abnormal activity in the liver, adrenal gland, and pancreas. MRI of the abdomen demonstrated two 6-7 cm masses in the liver. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

“…A 18F-fluorodeoxyglucose positron emission tomography showed no significant metabolic activity in the left adrenal gland but intense uptake in the supra- and subdiaphragmatic brown adipose tissue, probably due to noradrenergic-stimulated glucose uptake. …”
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Role of radiologists in the diagnosis and management of adrenal disorders by Sota Oguro, Hiromitsu Tannai, Hideki Ota, Kazumasa Seiji, Hiroki Kamada, Yoshitaka Toyama, Kei Omata, Yuta Tezuka, Yoshikiyo Ono, Fumitoshi Satoh, Sadayoshi Ito, Tetsuhiro Tanaka, Hideki Katagiri, Kei Takase

“…Collaborative approaches across clinical departments are required to enhance patient management in medical care involving the adrenal gland.…”
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Primary Aldosteronism Associated with Multiple Adrenocortical Micronodules in a Patient with Renal Cell Carcinoma by Kazuhito Oba, Yuko Chiba, Yoko Matsuda, Takeshi Kumakawa, Rie Aoyama, Miho Akahoshi, Seiji Hashimoto, Aya Tachibana, Koichi Toyoshima, Remi Kodera, Kenji Toyoshima, Yoshiaki Tamura, Takashi Nagata, Yuto Yamazaki, Hironobu Sasano, Atsushi Araki

“…However, the adrenocorticotrophic hormone stimulation test was positive; considering the possibility of slight aldosterone overproduction from the right adrenal gland, the administration of spironolactone was started. …”
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THE RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH ADRENAL TUMORS by A. A. Kostin, N. V. Vorobyev, A. O. Tolkachev, A. G. Muradyan, S. V. Popov

“…Currently, the main objective is the identification and operative treatment of malignant tumors of the adrenal glands in the early stages of the disease, which allows to improve the results of relapse-free and  overall survival. …”
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Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure by A. R. Tejeda-Martínez, J. M. Viveros-Paredes, G. V. Hidalgo-Franco, E. Pardo-González, V. Chaparro-Huerta, R. E. González-Castañeda, M. E. Flores-Soto

“…Alterations at the HPA axis level were analyzed using the relative weight of adrenal glands and serum corticosterone levels. Oxidative stress and brain-derived neurotrophic factor (BDNF) were also evaluated. …”
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Genetic Nurture Effects on Type 2 Diabetes Among Chinese Han Adults: A Family-Based Design by Xiaoyi Li, Zechen Zhou, Yujia Ma, Kexin Ding, Han Xiao, Tao Wu, Dafang Chen, Yiqun Wu

“…We observed significant gene enrichment in paternal genetic nurture effects in the gallbladder, smooth muscle, and adrenal gland tissues. <b>Conclusions</b>: <i>MRPS33</i>, <i>PIH1D2</i>, and <i>SD1HD</i> are associated with increased T2D risk through the environment influenced by paternal genotype, suggesting a novel perspective on paternal contributions to the T2D predisposition.…”
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Characterization of the C5H11ORF96 gene in chickens: cloning, tissue distribution and investigation of its potential function in stress response regulation by Yiping Wan, Jiannan Zhang, Xiao Zhang, Jiliang He, Ningkun Shi, Yuanyou Li, Juan Li, Yajun Wang

“…Our results showed that: (1) cC5H11ORF96 cDNA encodes a 120 amino acids protein, which shares high sequence identity with that of birds, mammals, reptiles, frogs and fish; (2) cC5H11ORF96 has a fully conserved RFKTQP motif and high proportion of serine, indicating its multiple potential phosphorylation sites; (3) cC5H11ORF96 is widely expressed in various chicken tissues, with high expression levels in the parathyroid gland, adrenal gland, and pituitary; (4) glucocorticoids (GCs) and stress significantly upregulate C5H11ORF96 mRNA and protein expression in the chicken pituitary and hypothalamus, suggesting its involvement in regulating stress response by influencing the negative feedback of GCs on the HPA axis in chickens. …”
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Silent Intravascular Lymphoma Initially Manifesting as a Unilateral Adrenal Incidentaloma by Yoshiko Takahashi, Keiji Iida, Yasuhisa Hino, Takeshi Ohara, Toshifumi Kurahashi, Takashi Tashiro, Kazuo Chihara

“…Although the involvement of adrenal glands in IVLBCL is often observed, primary adrenal IVLBCL is rare. …”
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Role of hypothalamic-pituitary-adrenal axis and catecholamine factors in independent and primary multiple types of tumor growth by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, Yu. A. Pogorelova, N. D. Cheryarina, L. K. Trepitaki, I. V. Neskubina, A. A. Vereskunova, I. M. Kotieva, K. A. Shumarin, A. I. Shikhlyarova, I. V. Goroshinskaya

“…To study the levels of adrenal axis factors in the hypothalamus, adrenal glands, blood serum of mice and catecholamines in the adrenal glands during the independent growth of B16 melanoma and Lewis lung carcinoma (LLC) and their combined growth in female mice, and in males – with independent growth of B16 and combined growth of B16 and LLC.Materials and methods. …”
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Relapse of Multiple Myeloma Presenting as Extramedullary Plasmacytomas in Multiple Organs by Murat Köse, Ersida Buraniqi, Timur Selçuk Akpinar, Seyit Mehmet Kayacan, Tufan Tükek

“…In addition to renal failure, anemia, hypercalcemia, lytic bone lesions, and immunodeficiency, it also affects multiple organ system, such as pancreas, adrenal glands, kidney, skin, lung, liver, spleen, lymph nodes, and bone. …”
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Rectal Metastases from Squamous Cell Carcinoma: A Case Report and Review of the Literature by S. Cedrés, N. Mulet-Margalef, M. A. Montero, P. Martinez, A. Martínez, E. Felip

“…The most frequent sites of distant metastasis are the liver, adrenal glands, bones and brain. Gastrointestinal metastases are uncommon and rectal metastases are extremely rare. …”
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Bilateral Bulky Adrenal Plasmacytomas with Very Good Response to Daratumumab-Based Therapy by Fang-Yu Wang, Han-Kuang Hsieh, Tso-Fu Wang, Yi-Feng Wu

“…In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy.…”
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Idiopathic Spontaneous Adrenal Hemorrhage in the Third Trimester of Pregnancy by Narin Nasiroglu Imga, Yasemin Tutuncu, Mazhar Muslum Tuna, Berçem Ayçıçek Doğan, Dilek Berker, Serdar Guler

“…Spontaneous adrenal hemorrhage (SAH) is seen in the absence of trauma or adrenal tumor in adrenal glands. The incidence of SAH has been reported from 0.14% to 1.1% and it usually involves the right gland. …”
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Social Isolation Stress Induces Anxious-Depressive-Like Behavior and Alterations of Neuroplasticity-Related Genes in Adult Male Mice by Alessandro Ieraci, Alessandra Mallei, Maurizio Popoli

“…SI mice exhibited reduced plasma corticosterone levels and reduced difference between right and left adrenal glands. SI showed lower mRNA levels of the BDNF-7 splice variant, c-Fos, Arc, and Egr-1 in both hippocampus and prefrontal cortex compared to GH mice. …”
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Extra-Adrenal Retroperitoneal Myelolipoma Resected by Laparoscopy in an Asymptomatic Patient by Gabriel Ambrogi, Maria Madureira Murta, André Silva Guimarães Moeda, Ramon Brandão Barbosa, Israel Rodrigues da Silva, Ana Beatriz Tabosa Negrão Xavier, Matheus Vieira dos Santos, Lucas Martinucci de Oliveira, Bernardo Luiz Campanário Precht, Renato Panhoca, Luis Augusto Seabra Rios

“…Myelolipomas are rare benign neoplasms that commonly develop in the adrenal glands. Less frequently, they can affect other organs such as the liver, stomach, liver, lung, and retroperitoneum. …”
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