Identification of Two Novel Mutations of ABCD1 Gene in Pedigrees with X-Linked Adrenoleukodystrophy and Review of the Literature by Bingzi Dong, Wenshan Lv, Lili Xu, Yuhang Zhao, Xiaofang Sun, Zhongchao Wang, Bingfei Cheng, Zhengju Fu, Yangang Wang

“…X-ALD is characterized as the childhood, adolescent, adult cerebral ALD, adrenomyeloneuropathy (AMN), adrenal insufficiency, and asymptomatic phenotypes, exhibiting a high variety of clinical neurological manifestations with or without adrenocortical insufficiency. …”
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Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia by Mary Kay Koenig, Vincenzo Leuzzi, Riadh Gouider, Riadh Gouider, Eppie M. Yiu, Eppie M. Yiu, Barbara Pietrucha, Asbjørg Stray-Pedersen, Susan L. Perlman, Steve Wu, Trudy Burgers, Rupam Borgohain, Rukmini Mridula Kandadai, Isabelle Meyts, Giorgia Bucciol, Anaita Udwadia-Hegde, Ravi Yadav, Donna Roberts, Aaron Dane, Maureen Roden, Dirk Thye, Biljana Horn, Howard M. Lederman, William P. Whitehouse

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Association between Polyunsaturated Fatty Acid Profile and Bronchial Inflammation in Bronchiolitis Obliterans by Silvija P. Jerkic, Laura Bächle, Ruth Pia Duecker, Lucia Gronau, Andreas G. Chiocchetti, Stefan Zielen, Ralf Schubert

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Assessment of Factors Affecting the Implementation of Integrated Management of Neonatal and Childhood Illness for Treatment of under Five Children by Health Professional in Health... by Ayele Mamo Abebe, Mesfin Wudu Kassaw, Fikir Alebachew Mengistu

“…The WHO Department of Child and Adolescent Health and Development (CAH), in collaboration with eleven other WHO programmes and UNICEF, has responded to this challenge by developing the Integrated Management of Childhood Illness (IMCI) strategy. …”
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Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis by Fenli Shao, Qianqian Liu, Yuyu Zhu, Zhidan Fan, Wenjun Chen, Shijia Liu, Xiaohui Li, Wenjie Guo, Gen-Sheng Feng, Haiguo Yu, Qiang Xu, Yang Sun

“…It is worth emphasizing that such pathological thickness of growth plates was evident in adolescent humans with enthesitis-related arthritis, which could progress to AS in adulthood. …”
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Comparing apples and oranges in youth depression treatments? A quantitative critique of the evidence base and guidelines by Samuele Cortese, Glyn Lewis, Argyris Stringaris, Georgina Krebs, Marinos Kyriakopoulos, Lucy Foulkes, Carmen Moreno, Charlotte Burman, Raphaelle Delpech, Rudolph Uher, Dayna Bhudia, Despoina Miliou, Ioannis-Marios Rokas

“…In this paper, we test the factors across modalities that may influence comparability between medication and psychotherapy trials.Methods We included 92 randomised controlled trials (RCTs) of psychotherapy and medication for child and adolescent depression (mean age 4–18 years). Using meta-analyses, we compared (a) participant characteristics and (b) trial characteristics in medication and psychotherapy trials. …”
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Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care by Simone Foti Randazzese, Mariarosaria La Rocca, Bruno Bombaci, Alessandra Di Pisa, Elèna Giliberto, Teresa Inturri, Daniel Militi, Fortunato Lombardo, Eloisa Gitto, Giuseppina Salzano, Stefano Passanisi

“…Diabetic ketoacidosis is the most common acute complication in children and adolescents with type 1 diabetes, and contributes significantly to morbidity, mortality, and healthcare burden. …”
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Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

“…Following multidisciplinary discussion, transcervical tracheal resection with limited manubriectomy was successfully performed, without the need for cardiopulmonary bypass, in an adolescent male on ERT with the severe airway manifestations of Morquio A syndrome. …”
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CAN WE PREDICT INCIPIENT DIABETES MELLITUS IN PATIENTS WITH TRANSFUSION DEPENDENT β-THALASSEMIA (β-TDT) REFERRED WITH A HISTORY OF PREDIABETES? by Vincenzo De Sanctis, Ashraf Soliman, Shahina Daar, Ploutarchos Tzoulis, Christos Kattamis

“…Setting: The study was mainly conducted at the Pediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara (Italy) in collaboration with thalassemia referring centers across Italy. …”
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REFERENCE POINTS OF THE PATHOGENESIS OF THE PHENOMENON OF MODEL FORMATION RISKY REPRODUCTIVE BEHAVIOR TEENAGE GIRLS by Ирина Вячеславовна Бабенко-Сорокопуд

“…Protection of the reproductive health of teenage girls and women is one of the priority medical and social tasks in the whole world, including the Donetsk region The aim of the research – to expand and supplement the understanding of the main links in the phenomenon of the formation of a model of risky reproductive behavior in adolescent girls with menstrual disorders in modern socio-demographic conditions. …”
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Pubertal Pathways in Girls Enrolled in a Contemporary British Cohort by Krista Yorita Christensen, Mildred Maisonet, Carol Rubin, Adrianne Holmes, W. Dana Flanders, Jon Heron, Jean Golding, Michael A. McGeehin, Michele Marcus

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The Role of Immersive Experience in Anxiety Reduction: Evidence from Virtual Reality Sessions by Dominika Wilczyńska, Tamara Walczak-Kozłowska, David Alarcón, María José Arenilla, Jose Carlos Jaenes, Marcelina Hejła, Mariusz Lipowski, Joanna Nestorowicz, Henryk Olszewski

“…We assessed immersion in VR using the Polish adaptation of the Immersion Questionnaire and anxiety using the Polish adaptations of the State–Trait Anxiety Inventory (STAI-X1) and its early adolescent version, the State–Trait Anxiety Inventory–Children (STAI-C1). …”
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Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta by Ahmed Younis, Yogesh N.V. Reddy, William R. Miranda, Ahmed T. Abdelhalim, Barry A. Borlaug, Heidi M. Connolly, Alexander C. Egbe

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Evaluation of anxiety in children diagnosed with chronic urticaria by Ugur Altas, Halil Alkaya, Seda Cevik, Mehmetcan Sezer, Firat Oz, Zeynep Meva Altas, Mehmet Yasar Ozkars

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Interleukin-15 (IL-15) and Anti-C1q Antibodies as Serum Biomarkers for Ectopic Pregnancy and Missed Abortion by Alexandros Daponte, Efthimios Deligeoroglou, Spyros Pournaras, Christos Hadjichristodoulou, Antonios Garas, Foteini Anastasiadou, Ioannis E. Messinis

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Insights From Diverse Perspectives on Social Media Messages to Inform Young Adults With Cancer About Clinical Trials: Focus Group Study by Melissa P Beauchemin, Desiree Walker, Allison Rosen, Maria Frazer, Meital Eisenberger, Rhea K Khurana, Edward Bentlyewski, Victoria Fedorko, Corey H Basch, Grace C Hillyer

“… Abstract BackgroundLow rates of adolescent and young adult (YA; aged 15-39 y) clinical trial enrollment (CTE), particularly among underserved groups, have resulted in a lack of standardized cancer treatments and follow-up guidelines for this group that may limit improvement in cancer treatments and survival outcomes for YAs. …”
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Early Maternal Deprivation Enhances Voluntary Alcohol Intake Induced by Exposure to Stressful Events Later in Life by Sara Peñasco, Virginia Mela, Jose Antonio López-Moreno, María-Paz Viveros, Eva M. Marco

“…In the present study, we aimed to assess the impact of early life stress, in the form of early maternal deprivation (MD, 24 h on postnatal day, pnd, 9), on voluntary alcohol intake in adolescent male and female Wistar rats. During adolescence, from pnd 28 to pnd 50, voluntary ethanol intake (20%, v/v) was investigated using the two-bottle free choice paradigm. …”
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Exercise interventions to improve bone mineral density in athletes participating in low-impact sports: a scoping review by Anders Gulbrandsen Florvåg, Øyvind Angelshaug Berg, Ola Drange Røksund, Gøril Tvedten Jorem, Bård Erik Bogen

“…Five populations were explored; one cohort of adolescent swimmers (both sexes), one cohort of female Olympic artistic swimmers, one cohort of elite road cyclists (both sexes), one cohort of male competitive amateur cyclists, and one cohort of trained to well-trained cyclists (both sexes). …”
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Overweight and Obesity Based on Four Reference Systems in 18,382 Paediatric Patients with Type 1 Diabetes from Germany and Austria by M. Flechtner-Mors, K. O. Schwab, E. E. Fröhlich-Reiterer, T. M. Kapellen, T. Meissner, J. Rosenbauer, R. Stachow, R. W. Holl

“…Using WHO, IOTF, AGA (German pediatric obesity), and KiGGS (German Health Interview and Examination Survey for Children and Adolescents) reference populations, prevalence of overweight (≥90th percentile) and obesity (≥97th percentile) and time trend between 2000 (n = 9,461) and 2013 (n = 18,382) were determined in 2–18-year-old T1D patients documented in the German/Austrian DPV database. …”
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Association of food security with cardiometabolic health during young adulthood: cross-sectional comparison of American Indian adults with other racial/ethnic groups by Cassandra J Nikolaus, Anna Zamora-Kapoor, Luciana E Hebert, Ka'imi Sinclair

“…Objectives Our aim was to assess the cross-sectional associations between food insecurity and cardiometabolic health indicators in American Indian young adults compared with non-Hispanic white, black, Asian or Pacific Islander and Hispanic young adults.Design Data from the fourth wave of the National Longitudinal Study of Adolescent to Adult Health (Add Health) were used. Variables included a self-assessed measure of risk of food insecurity, indicators of cardiometabolic health (body mass index, haemoglobin A1c, blood pressure) and sociodemographic characteristics. …”
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